NO313034B1 - Innretning for å dispensere enkeltdoser av et partikkelformet materiale - Google Patents
Innretning for å dispensere enkeltdoser av et partikkelformet materiale Download PDFInfo
- Publication number
- NO313034B1 NO313034B1 NO19962562A NO962562A NO313034B1 NO 313034 B1 NO313034 B1 NO 313034B1 NO 19962562 A NO19962562 A NO 19962562A NO 962562 A NO962562 A NO 962562A NO 313034 B1 NO313034 B1 NO 313034B1
- Authority
- NO
- Norway
- Prior art keywords
- container
- housing
- chambers
- airway
- cartridge
- Prior art date
Links
- 239000011236 particulate material Substances 0.000 title claims description 6
- 239000003814 drug Substances 0.000 claims abstract description 27
- 239000000463 material Substances 0.000 claims abstract description 21
- 229940079593 drug Drugs 0.000 claims description 24
- 239000000843 powder Substances 0.000 claims description 11
- 238000007789 sealing Methods 0.000 claims description 7
- 239000012528 membrane Substances 0.000 claims description 4
- 230000009471 action Effects 0.000 claims description 3
- 230000000694 effects Effects 0.000 claims description 2
- 239000012190 activator Substances 0.000 claims 1
- 239000012254 powdered material Substances 0.000 abstract description 4
- 230000007246 mechanism Effects 0.000 abstract description 2
- 239000011888 foil Substances 0.000 description 15
- 238000000034 method Methods 0.000 description 5
- 208000006673 asthma Diseases 0.000 description 4
- 238000005096 rolling process Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 230000004913 activation Effects 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000005801 respiratory difficulty Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/005—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a cylindrical surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Disintegrating Or Milling (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicinal Preparation (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Packages (AREA)
- Steroid Compounds (AREA)
- Cyclones (AREA)
- Separation Of Particles Using Liquids (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939325835A GB9325835D0 (en) | 1993-12-18 | 1993-12-18 | Device for administering single doses of a medicament |
| GB9409841A GB9409841D0 (en) | 1993-12-18 | 1994-05-17 | Device for administering single doses of a particulate material |
| PCT/GB1994/002716 WO1995016483A1 (en) | 1993-12-18 | 1994-12-09 | Powder inhalator |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO962562D0 NO962562D0 (no) | 1996-06-17 |
| NO962562L NO962562L (no) | 1996-06-17 |
| NO313034B1 true NO313034B1 (no) | 2002-08-05 |
Family
ID=26304040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19962562A NO313034B1 (no) | 1993-12-18 | 1996-06-17 | Innretning for å dispensere enkeltdoser av et partikkelformet materiale |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5769073A (pl) |
| EP (1) | EP0732952B1 (pl) |
| JP (1) | JP3597196B2 (pl) |
| CN (1) | CN1133470C (pl) |
| AT (1) | ATE192341T1 (pl) |
| AU (1) | AU687489B2 (pl) |
| BR (1) | BR9408333A (pl) |
| CA (1) | CA2179202C (pl) |
| CZ (1) | CZ286060B6 (pl) |
| DE (1) | DE69424310T2 (pl) |
| DK (1) | DK0732952T3 (pl) |
| EE (1) | EE03225B1 (pl) |
| ES (1) | ES2148477T3 (pl) |
| FI (1) | FI109404B (pl) |
| GR (1) | GR3034071T3 (pl) |
| HU (1) | HU219215B (pl) |
| NO (1) | NO313034B1 (pl) |
| NZ (1) | NZ277290A (pl) |
| PL (1) | PL177038B1 (pl) |
| PT (1) | PT732952E (pl) |
| SK (1) | SK282117B6 (pl) |
| WO (1) | WO1995016483A1 (pl) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA26230A (uk) * | 1990-03-02 | 1999-07-19 | Глексо Груп Лімітед | Іhгалятор для спільhого використаhhя з лікувальhим блоком і лікувальhий блок |
| GB9004781D0 (en) * | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| US6536427B2 (en) | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
| SK280968B6 (sk) | 1990-03-02 | 2000-10-09 | Glaxo Group Limited | Balenie medikamentu na použite v inhalačnom prístroji |
| GB9409851D0 (en) * | 1994-05-17 | 1994-07-06 | Cambridge Consultants | Improvements in and relating to containers of particulate material |
| GB9409852D0 (en) * | 1994-05-17 | 1994-07-06 | Cambridge Consultants | Device for administering single doses of a medicament |
| US6672304B1 (en) | 1995-06-08 | 2004-01-06 | Innovative Devices, Llc | Inhalation actuated device for use with metered dose inhalers (MDIs) |
| US20040237961A1 (en) * | 1995-06-08 | 2004-12-02 | Snow John Medlin | Inhalation actuated device for use with metered dose inhalers (MDIs) |
| CA2212430A1 (en) * | 1997-08-07 | 1999-02-07 | George Volgyesi | Inhalation device |
| US6237590B1 (en) * | 1997-09-18 | 2001-05-29 | Delsys Pharmaceutical Corporation | Dry powder delivery system apparatus |
| US6014972A (en) * | 1997-12-11 | 2000-01-18 | Thayer Medical Corporation | Dry drug particle delivery system and method for ventilator circuits |
| US6164275A (en) * | 1999-01-19 | 2000-12-26 | Van Iderstine; Lois | Inhaler carrier |
| ATE306291T1 (de) | 1999-01-22 | 2005-10-15 | Glaxo Group Ltd | Inhalationsvorrichtung |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6606992B1 (en) | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
| ATE271400T1 (de) * | 1999-10-12 | 2004-08-15 | Shl Medical Ab | Inhalateur |
| US7304750B2 (en) | 1999-12-17 | 2007-12-04 | Nektar Therapeutics | Systems and methods for non-destructive mass sensing |
| DE19961300A1 (de) * | 1999-12-18 | 2001-06-21 | Asta Medica Ag | Vorratssystem für Arzneimittel in Pulverform und damit ausgestatteter Inhalator |
| AR028746A1 (es) † | 2000-06-23 | 2003-05-21 | Norton Health Care Ltd | Cartucho de dosis previamente medidas para inhalador de polvo seco accionado por la respiracion, el inhalador y un metodo de provision de dosis previamente medidas de polvo seco |
| GB0023653D0 (en) * | 2000-09-27 | 2000-11-08 | Cambridge Consultants | Device for dispensing particulate material |
| GB0025749D0 (en) * | 2000-10-20 | 2000-12-06 | Glaxo Group Ltd | Inhaler |
| WO2002085281A1 (en) * | 2001-04-19 | 2002-10-31 | Technology Innovation Limited | Medicament container |
| UA88863C2 (ru) * | 2001-06-15 | 2009-12-10 | Оцука Фармасьютікал Ко., Лтд. | Система для ингаляции сухим порошком, лиофилизированный состав, ингалятор сухого порошка (варианты), способ изготовления сухого порошкообразного препарата для транспульмонарного применения, способ транспульмонарного применения, применение лиофилизированного состава для транспульмонарного применения при помощи ингаляции (варианты) |
| GB0130055D0 (en) | 2001-12-14 | 2002-02-06 | Technology Innovation Ltd | Medicament packaging |
| US7258118B2 (en) * | 2002-01-24 | 2007-08-21 | Sofotec Gmbh & Co, Kg | Pharmaceutical powder cartridge, and inhaler equipped with same |
| SI1494732T1 (sl) * | 2002-03-20 | 2008-08-31 | Mannking Corp | Inhalacijski aparat |
| DE10300032B3 (de) * | 2003-01-03 | 2004-05-27 | E. Braun Gmbh | Pulverinhalator |
| WO2004082557A2 (en) | 2003-03-15 | 2004-09-30 | Brin Tech International Limited | Package for and formulation of medicaments |
| EP1522325B1 (en) * | 2003-10-06 | 2007-06-13 | Bang & Olufsen Medicom A/S | Inhaler |
| GB2407042B (en) * | 2003-10-17 | 2007-10-24 | Vectura Ltd | Inhaler |
| WO2005044173A1 (en) * | 2003-10-27 | 2005-05-19 | Oriel Therapeutics, Inc. | Blister packages and associated methods of fabricating dry powder drug containment systems |
| EP1786784B1 (en) | 2004-08-20 | 2010-10-27 | MannKind Corporation | Catalysis of diketopiperazine synthesis |
| MX2007002189A (es) | 2004-08-23 | 2008-01-11 | Mannkind Corp | Sales de dicetopiperazina, sales de dicetomorfolina o sales de dicetodioxano para suministro de farmacos. |
| WO2006031712A2 (en) * | 2004-09-13 | 2006-03-23 | Oriel Therapeutics, Inc. | Tubular dry powder drug containment systems, associated inhalers and methods |
| US7216622B2 (en) * | 2004-10-01 | 2007-05-15 | Federal-Mogul World Wide, Inc. | Wiring harness with integrated component heat shield |
| GB0507711D0 (en) * | 2005-04-15 | 2005-05-25 | Vectura Group Plc | Improved blister piercing |
| JP2008539839A (ja) * | 2005-05-04 | 2008-11-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 複数回投与量の医薬組成物を含有する吸入装置 |
| AU2006283113B2 (en) * | 2005-08-25 | 2011-12-01 | Oriel Therapeutics, Inc. | Drug containment systems with sticks, related kits, dry powder inhalers and methods |
| CN102614131A (zh) | 2005-09-14 | 2012-08-01 | 曼金德公司 | 以提高结晶微粒表面对活性试剂的亲和力为基础的药物配制方法 |
| US7987845B2 (en) * | 2006-01-31 | 2011-08-02 | Oriel Therapeutics, Inc. | Dry powder inhalers having spiral travel paths, unit dose microcartridges with dry powder, related devices and methods |
| BRPI0707991B8 (pt) | 2006-02-22 | 2021-05-25 | Mannkind Corp | métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco |
| DE102006029753A1 (de) * | 2006-03-10 | 2007-09-13 | Alfred Von Schuckmann | Inhalator für pulverförmige Substanzen |
| EP1925295A1 (de) | 2006-11-22 | 2008-05-28 | Boehringer Ingelheim Pharma GmbH & Co. KG | Stabile Pulverformulierung enthaltend ein Anticholinergikum |
| US20080142007A1 (en) * | 2006-12-15 | 2008-06-19 | Norton Healthcare Ltd | Medicament dispenser for an inhaler |
| AU2008269282A1 (en) | 2007-06-28 | 2008-12-31 | Inhalation Sciences Sweden Ab | Exposure system |
| DK2230934T3 (da) | 2007-12-14 | 2012-11-26 | Aerodesigns Inc | Afgivelse af aerosoliserbare næringsmiddelprodukter |
| KR101629154B1 (ko) | 2008-06-13 | 2016-06-21 | 맨카인드 코포레이션 | 건조 분말 흡입기 및 약물 투여 시스템 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| CA2728523C (en) | 2008-06-20 | 2020-03-10 | Mannkind Corporation | An interactive apparatus and method for real-time profiling of inhalation efforts |
| WO2010014340A1 (en) * | 2008-07-26 | 2010-02-04 | Hewlett-Packard Development Company, L.P. | Fluid supply contact |
| TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
| JP5470393B2 (ja) | 2008-09-26 | 2014-04-16 | オリエル・セラピューティクス，インコーポレイテッド | ドライパウダー吸入器 |
| WO2010036839A2 (en) | 2008-09-26 | 2010-04-01 | Oriel Therapeutics, Inc. | Inhalers with airway disks having discrete airway channels and related disks and methods |
| MX2011003232A (es) * | 2008-09-26 | 2011-04-21 | Oriel Therapeutics Inc | Mecanismos inhaladaores con perforadores radialmente desviados y métodos relacionados. |
| WO2010039201A2 (en) * | 2008-09-30 | 2010-04-08 | Oriel Therapeutics, Inc. | Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods |
| MX2011003245A (es) * | 2008-10-01 | 2011-04-26 | Oriel Therapeutics Inc | Inhaladores de polvo seco con mecanismos de perforacion giratorios y dispositivos y metodos relacionados. |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| WO2010105094A1 (en) | 2009-03-11 | 2010-09-16 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| JP5859433B2 (ja) | 2009-06-12 | 2016-02-10 | マンカインド コーポレイション | 規定された比表面積を有するジケトピペラジン微粒子 |
| US9016147B2 (en) | 2009-11-03 | 2015-04-28 | Mannkind Corporation | Apparatus and method for simulating inhalation efforts |
| USD641076S1 (en) | 2010-03-26 | 2011-07-05 | Oriel Therapeutics, Inc. | Dry powder inhaler |
| USD635246S1 (en) | 2010-03-26 | 2011-03-29 | Oriel Therapeutics, Inc. | Dose disk for dry powder inhalers |
| JP6385673B2 (ja) | 2010-06-21 | 2018-09-05 | マンカインド コーポレイション | 乾燥粉末薬物送達システム |
| US8925726B2 (en) | 2011-04-01 | 2015-01-06 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2012171443A1 (zh) * | 2011-06-13 | 2012-12-20 | 上海秀新臣邦医药科技有限公司 | 一种干粉给药装置 |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| BR112014009686A2 (pt) | 2011-10-24 | 2018-08-07 | Mannkind Corp | composição analgésica inalável, pó seco e método para tratar dor |
| ES2624294T3 (es) | 2012-07-12 | 2017-07-13 | Mannkind Corporation | Sistemas de suministro de fármacos en polvo seco |
| US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
| GB201301192D0 (en) | 2013-01-23 | 2013-03-06 | Vectura Delivery Devices Ltd | A blister piercing element for a dry powder inhaler |
| CN108578372B (zh) | 2013-03-15 | 2021-07-06 | 曼金德公司 | 微晶二酮哌嗪组合物以及方法 |
| MX2020009878A (es) | 2013-07-18 | 2022-07-27 | Mannkind Corp | Composiciones farmaceuticas en polvo seco estables al calor y metodos. |
| EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
| WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10933207B2 (en) | 2014-08-26 | 2021-03-02 | Asmedic Ltd. | Drug delivery apparatus |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| USD771242S1 (en) * | 2015-04-10 | 2016-11-08 | Enmodes Gmbh | Cannula |
| RU2768358C2 (ru) | 2017-07-21 | 2022-03-23 | Филип Моррис Продактс С.А. | Генерирующее аэрозоль устройство со спиральным перемещением для нагрева и генерирующая аэрозоль система |
| WO2020115306A1 (en) * | 2018-12-07 | 2020-06-11 | Philip Morris Products S.A. | Aerosol-generating system and cartridge with leakage protection |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0407028B2 (en) * | 1989-05-31 | 1999-07-07 | FISONS plc | Medicament inhalation device and formulation |
| DK544589D0 (da) * | 1989-11-01 | 1989-11-01 | Novo Nordisk As | Manuel betjent apparat til dispensering af en forudbestemt maengde af et pulverformet stof |
| GB9015522D0 (en) * | 1990-07-13 | 1990-08-29 | Braithwaite Philip W | Inhaler |
| US5492112A (en) * | 1991-05-20 | 1996-02-20 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| US5337740A (en) * | 1991-08-01 | 1994-08-16 | New England Pharmaceuticals, Inc. | Inhalation devices |
| DE4211475A1 (de) * | 1991-12-14 | 1993-06-17 | Asta Medica Ag | Pulverinhalator |
| WO1993024166A2 (en) * | 1992-06-04 | 1993-12-09 | Glaxo Group Limited | Inhalation device |
| US5388572A (en) * | 1993-10-26 | 1995-02-14 | Tenax Corporation (A Connecticut Corp.) | Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same |
-
1994
- 1994-12-09 NZ NZ277290A patent/NZ277290A/en unknown
- 1994-12-09 EE EE9600059A patent/EE03225B1/xx not_active IP Right Cessation
- 1994-12-09 EP EP95903413A patent/EP0732952B1/en not_active Expired - Lifetime
- 1994-12-09 CZ CZ961732A patent/CZ286060B6/cs not_active IP Right Cessation
- 1994-12-09 CA CA002179202A patent/CA2179202C/en not_active Expired - Fee Related
- 1994-12-09 DK DK95903413T patent/DK0732952T3/da active
- 1994-12-09 PL PL94314957A patent/PL177038B1/pl not_active IP Right Cessation
- 1994-12-09 ES ES95903413T patent/ES2148477T3/es not_active Expired - Lifetime
- 1994-12-09 AU AU12470/95A patent/AU687489B2/en not_active Ceased
- 1994-12-09 PT PT95903413T patent/PT732952E/pt unknown
- 1994-12-09 JP JP51659695A patent/JP3597196B2/ja not_active Expired - Fee Related
- 1994-12-09 WO PCT/GB1994/002716 patent/WO1995016483A1/en active IP Right Grant
- 1994-12-09 BR BR9408333A patent/BR9408333A/pt not_active IP Right Cessation
- 1994-12-09 CN CNB941945200A patent/CN1133470C/zh not_active Expired - Fee Related
- 1994-12-09 US US08/663,245 patent/US5769073A/en not_active Expired - Fee Related
- 1994-12-09 DE DE69424310T patent/DE69424310T2/de not_active Expired - Fee Related
- 1994-12-09 AT AT95903413T patent/ATE192341T1/de not_active IP Right Cessation
- 1994-12-09 SK SK797-96A patent/SK282117B6/sk unknown
- 1994-12-09 HU HU9601647A patent/HU219215B/hu not_active IP Right Cessation
-
1996
- 1996-06-17 NO NO19962562A patent/NO313034B1/no unknown
- 1996-06-17 FI FI962520A patent/FI109404B/fi not_active IP Right Cessation
-
2000
- 2000-07-31 GR GR20000401763T patent/GR3034071T3/el not_active IP Right Cessation
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