DE69424310D1 - Pulverinhalator - Google Patents

Pulverinhalator

Info

Publication number
DE69424310D1
DE69424310D1 DE69424310T DE69424310T DE69424310D1 DE 69424310 D1 DE69424310 D1 DE 69424310D1 DE 69424310 T DE69424310 T DE 69424310T DE 69424310 T DE69424310 T DE 69424310T DE 69424310 D1 DE69424310 D1 DE 69424310D1
Authority
DE
Germany
Prior art keywords
pct
airway
container
compartment
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69424310T
Other languages
English (en)
Other versions
DE69424310T2 (de
Inventor
William Eason
Patrick Catterall
William Clarke
Joy Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939325835A external-priority patent/GB9325835D0/en
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of DE69424310D1 publication Critical patent/DE69424310D1/de
Publication of DE69424310T2 publication Critical patent/DE69424310T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/005—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a cylindrical surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Disintegrating Or Milling (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Steroid Compounds (AREA)
  • Packages (AREA)
  • Separation Of Particles Using Liquids (AREA)
  • Cyclones (AREA)
DE69424310T 1993-12-18 1994-12-09 Pulverinhalator Expired - Fee Related DE69424310T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939325835A GB9325835D0 (en) 1993-12-18 1993-12-18 Device for administering single doses of a medicament
GB9409841A GB9409841D0 (en) 1993-12-18 1994-05-17 Device for administering single doses of a particulate material
PCT/GB1994/002716 WO1995016483A1 (en) 1993-12-18 1994-12-09 Powder inhalator

Publications (2)

Publication Number Publication Date
DE69424310D1 true DE69424310D1 (de) 2000-06-08
DE69424310T2 DE69424310T2 (de) 2001-01-04

Family

ID=26304040

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69424310T Expired - Fee Related DE69424310T2 (de) 1993-12-18 1994-12-09 Pulverinhalator

Country Status (22)

Country Link
US (1) US5769073A (de)
EP (1) EP0732952B1 (de)
JP (1) JP3597196B2 (de)
CN (1) CN1133470C (de)
AT (1) ATE192341T1 (de)
AU (1) AU687489B2 (de)
BR (1) BR9408333A (de)
CA (1) CA2179202C (de)
CZ (1) CZ286060B6 (de)
DE (1) DE69424310T2 (de)
DK (1) DK0732952T3 (de)
EE (1) EE03225B1 (de)
ES (1) ES2148477T3 (de)
FI (1) FI109404B (de)
GR (1) GR3034071T3 (de)
HU (1) HU219215B (de)
NO (1) NO313034B1 (de)
NZ (1) NZ277290A (de)
PL (1) PL177038B1 (de)
PT (1) PT732952E (de)
SK (1) SK282117B6 (de)
WO (1) WO1995016483A1 (de)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
UA26230A (uk) * 1990-03-02 1999-07-19 Глексо Груп Лімітед Іhгалятор для спільhого використаhhя з лікувальhим блоком і лікувальhий блок
SK280967B6 (sk) 1990-03-02 2000-10-09 Glaxo Group Limited Inhalačný prístroj
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
GB9409851D0 (en) * 1994-05-17 1994-07-06 Cambridge Consultants Improvements in and relating to containers of particulate material
GB9409852D0 (en) * 1994-05-17 1994-07-06 Cambridge Consultants Device for administering single doses of a medicament
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
CA2212430A1 (en) * 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US6237590B1 (en) * 1997-09-18 2001-05-29 Delsys Pharmaceutical Corporation Dry powder delivery system apparatus
US6014972A (en) * 1997-12-11 2000-01-18 Thayer Medical Corporation Dry drug particle delivery system and method for ventilator circuits
US6164275A (en) * 1999-01-19 2000-12-26 Van Iderstine; Lois Inhaler carrier
JP2002535048A (ja) 1999-01-22 2002-10-22 グラクソ グループ リミテッド 吸入装置
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
EP1220698B1 (de) * 1999-10-12 2004-07-21 SHL Medical AB Inhalateur
US7304750B2 (en) 1999-12-17 2007-12-04 Nektar Therapeutics Systems and methods for non-destructive mass sensing
DE19961300A1 (de) 1999-12-18 2001-06-21 Asta Medica Ag Vorratssystem für Arzneimittel in Pulverform und damit ausgestatteter Inhalator
PE20020066A1 (es) † 2000-06-23 2002-02-23 Norton Healthcare Ltd Deposito de dosis medidas previamente para inhalador de polvo seco accionado por la respiracion
GB0023653D0 (en) * 2000-09-27 2000-11-08 Cambridge Consultants Device for dispensing particulate material
GB0025749D0 (en) * 2000-10-20 2000-12-06 Glaxo Group Ltd Inhaler
ATE452617T1 (de) * 2001-04-19 2010-01-15 Technology Innovation Ltd Arzneimittelbehälter
CN101366989B (zh) * 2001-06-15 2012-03-21 大塚制药株式会社 经肺给药用干燥粉末吸入系统
GB0130055D0 (en) 2001-12-14 2002-02-06 Technology Innovation Ltd Medicament packaging
US7258118B2 (en) * 2002-01-24 2007-08-21 Sofotec Gmbh & Co, Kg Pharmaceutical powder cartridge, and inhaler equipped with same
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
DE10300032B3 (de) * 2003-01-03 2004-05-27 E. Braun Gmbh Pulverinhalator
DE602004028585D1 (de) 2003-03-15 2010-09-23 Brin Tech Internat Ltd Verpackung für Arzneimittel
DE60314422T2 (de) * 2003-10-06 2008-02-21 Bang & Olufsen Medicom A/S Inhalator
GB2407042B (en) * 2003-10-17 2007-10-24 Vectura Ltd Inhaler
WO2005041848A2 (en) * 2003-10-27 2005-05-12 Oriel Therapeutics, Inc. Dry powder drug containment system packages with tabs, inhalers and associated methods
DE602005024413D1 (de) 2004-08-20 2010-12-09 Mannkind Corp Katalyse der diketopiperazinsynthese
ES2540886T3 (es) 2004-08-23 2015-07-14 Mannkind Corporation Sales de dicetopiperazina para la administración de fármacos
US8210171B2 (en) 2004-09-13 2012-07-03 Oriel Therapeutics, Inc. Tubular dry powder drug containment systems, associated inhalers and methods
US7216622B2 (en) * 2004-10-01 2007-05-15 Federal-Mogul World Wide, Inc. Wiring harness with integrated component heat shield
GB0507711D0 (en) * 2005-04-15 2005-05-25 Vectura Group Plc Improved blister piercing
US20090042843A1 (en) * 2005-05-04 2009-02-12 Boehringer Ingelheim International Gmbh Inhalation Device Containing Plural Doses of a Pharmaceutical Composition
AU2006283113B2 (en) * 2005-08-25 2011-12-01 Oriel Therapeutics, Inc. Drug containment systems with sticks, related kits, dry powder inhalers and methods
KR101557502B1 (ko) 2005-09-14 2015-10-06 맨카인드 코포레이션 결정질 미립자 표면에 대한 활성제의 친화력의 증가를기반으로 하는 약물 제제의 방법
EP1986722B1 (de) 2006-01-31 2018-10-24 Oriel Therapeutics, Inc. Trockenpulverinhalatoren mit spiralförmigen verabreichungswegen für mikrokartuschen mit trockenpulver
AU2007216966C1 (en) 2006-02-22 2014-03-20 Mannkind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
DE102006029753A1 (de) * 2006-03-10 2007-09-13 Alfred Von Schuckmann Inhalator für pulverförmige Substanzen
EP1925295A1 (de) 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
US20080142007A1 (en) * 2006-12-15 2008-06-19 Norton Healthcare Ltd Medicament dispenser for an inhaler
AU2008269282A1 (en) 2007-06-28 2008-12-31 Inhalation Sciences Sweden Ab Exposure system
EP2534957B1 (de) 2007-12-14 2015-05-27 AeroDesigns, Inc Abgabe von Aerosol-sprühbaren Produkten
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
PL2293833T3 (pl) 2008-06-13 2016-08-31 Mannkind Corp Inhalator proszkowy i układ do dostarczania leku
EP2609954B1 (de) 2008-06-20 2021-12-29 MannKind Corporation Interaktives Gerät für die Echtzeit-Profilierung von Inhalationsversuchen
WO2010014340A1 (en) * 2008-07-26 2010-02-04 Hewlett-Packard Development Company, L.P. Fluid supply contact
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
SI2346556T1 (sl) 2008-09-26 2015-02-27 Oriel Therapeutics, Inc. Inhalatorji za suhi prah z elementi za dvojno prebadanje in z njimi povezane naprave in postopki
ES2550309T3 (es) * 2008-09-26 2015-11-06 Oriel Therapeutics, Inc. Mecanismos inhaladores con perforadores predispuestos radialmente y métodos relacionados
ES2570128T3 (es) * 2008-09-26 2016-05-17 Oriel Therapeutics Inc Inhaladores con discos que tienen conductos de aire equipados con canales discretos de conductos de aire y discos y métodos relacionados
US9050427B2 (en) * 2008-09-30 2015-06-09 Oriel Therapeutics, Inc. Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods
EP2328645B1 (de) * 2008-10-01 2015-11-11 Oriel Therapeutics, Inc. Trockenpulverinhalatoren mit rotierenden einstichmechanismen sowie entsprechende vorrichtungen und verfahren
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2405963B1 (de) 2009-03-11 2013-11-06 MannKind Corporation Gerät, system und verfahren zur messung von widerstand in einem inhaliergerät
KR20180079458A (ko) 2009-06-12 2018-07-10 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
US9016147B2 (en) 2009-11-03 2015-04-28 Mannkind Corporation Apparatus and method for simulating inhalation efforts
USD635246S1 (en) 2010-03-26 2011-03-29 Oriel Therapeutics, Inc. Dose disk for dry powder inhalers
USD641076S1 (en) 2010-03-26 2011-07-05 Oriel Therapeutics, Inc. Dry powder inhaler
CA2801936C (en) 2010-06-21 2021-06-01 Mannkind Corporation Dry powder drug delivery system and methods
EP2694402B1 (de) 2011-04-01 2017-03-22 MannKind Corporation Blisterverpackung für pharmakartuschen
WO2012171443A1 (zh) * 2011-06-13 2012-12-20 上海秀新臣邦医药科技有限公司 一种干粉给药装置
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
EP2776053A1 (de) 2011-10-24 2014-09-17 MannKind Corporation Verfahren und zusammensetzungen zur schmerzbehandlung
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
GB201301192D0 (en) 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
KR102499439B1 (ko) 2013-03-15 2023-02-13 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
MX2020009878A (es) 2013-07-18 2022-07-27 Mannkind Corp Composiciones farmaceuticas en polvo seco estables al calor y metodos.
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
CN106794323B (zh) * 2014-08-26 2020-06-16 阿斯麦迪克有限公司 药物递送装置
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
USD771242S1 (en) * 2015-04-10 2016-11-08 Enmodes Gmbh Cannula
KR102573471B1 (ko) 2017-07-21 2023-09-01 필립모리스 프로덕츠 에스.에이. 가열을 위한 나선형 이동을 갖는 에어로졸 발생 장치
US20220022544A1 (en) * 2018-12-07 2022-01-27 Philip Morris Products S.A. Aerosol-generating system and cartridge with leakage protection

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE407028T1 (de) * 1989-05-31 1994-03-17 Fisons Plc Medikament und Inhalationsvorrichtung dafür.
DK544589D0 (da) * 1989-11-01 1989-11-01 Novo Nordisk As Manuel betjent apparat til dispensering af en forudbestemt maengde af et pulverformet stof
GB9015522D0 (en) * 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5337740A (en) * 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
WO1993024166A2 (en) * 1992-06-04 1993-12-09 Glaxo Group Limited Inhalation device
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same

Also Published As

Publication number Publication date
US5769073A (en) 1998-06-23
FI962520A0 (fi) 1996-06-17
FI962520A (fi) 1996-06-17
CZ286060B6 (cs) 1999-12-15
AU687489B2 (en) 1998-02-26
NZ277290A (en) 1998-03-25
SK282117B6 (sk) 2001-11-06
DE69424310T2 (de) 2001-01-04
JPH09510367A (ja) 1997-10-21
CA2179202A1 (en) 1995-06-22
CN1142779A (zh) 1997-02-12
WO1995016483A1 (en) 1995-06-22
HU9601647D0 (en) 1996-08-28
EE03225B1 (et) 1999-10-15
AU1247095A (en) 1995-07-03
CZ173296A3 (en) 1996-10-16
FI109404B (fi) 2002-07-31
NO313034B1 (no) 2002-08-05
SK79796A3 (en) 1997-03-05
HUT74234A (en) 1996-11-28
EP0732952B1 (de) 2000-05-03
GR3034071T3 (en) 2000-11-30
NO962562L (no) 1996-06-17
DK0732952T3 (da) 2000-09-25
PT732952E (pt) 2000-10-31
PL177038B1 (pl) 1999-09-30
PL314957A1 (en) 1996-09-30
JP3597196B2 (ja) 2004-12-02
NO962562D0 (no) 1996-06-17
CN1133470C (zh) 2004-01-07
ES2148477T3 (es) 2000-10-16
EP0732952A1 (de) 1996-09-25
HU219215B (en) 2001-03-28
BR9408333A (pt) 1997-08-19
CA2179202C (en) 2006-06-06
ATE192341T1 (de) 2000-05-15

Similar Documents

Publication Publication Date Title
DE69424310D1 (de) Pulverinhalator
US5533502A (en) Powder inhaler with aerosolization occurring within each individual powder receptacle
JP3570431B2 (ja) 計量装置
EP0640354B1 (de) Wirbelkammer-Pulverinhalator
JPH06503486A (ja) 吸引促進ガスを使用しない吸引装置
DE69722257D1 (de) Arzneiverabreichung und verpackung
CA2225396A1 (en) Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments
GB2340758A (en) Drug dispensing system
GB0205572D0 (en) Medicament delivery and packaging
ATE152920T1 (de) Inhalator
ATE374054T1 (de) Atmungsbetätigter inhalator
GB8914223D0 (en) Medicament container
ATE429944T1 (de) Inhaliervorrichtung
UA50712C2 (uk) Пристрій для дозованого видавання разових доз матеріалу із макрочастинок і змінний патрон для інгалятора
CA2235005A1 (en) Powder inhaler
MX9701196A (es) Aparato inhalador con camara de optimizacion.
CA2197758A1 (en) Inhaler apparatus with optimisation chamber

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee