NO312810B1 - Multilamell¶r liposomal arachidonsyre metabolitt formuleringer og en fremgangsmåte for fremstilling av etmedikament derav - Google Patents

Multilamell¶r liposomal arachidonsyre metabolitt formuleringer og en fremgangsmåte for fremstilling av etmedikament derav Download PDF

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Publication number
NO312810B1
NO312810B1 NO19961779A NO961779A NO312810B1 NO 312810 B1 NO312810 B1 NO 312810B1 NO 19961779 A NO19961779 A NO 19961779A NO 961779 A NO961779 A NO 961779A NO 312810 B1 NO312810 B1 NO 312810B1
Authority
NO
Norway
Prior art keywords
liposome
lipid
pgei
arachidonic acid
prostaglandin
Prior art date
Application number
NO19961779A
Other languages
English (en)
Norwegian (no)
Other versions
NO961779L (no
NO961779D0 (no
Inventor
Robert P Lenk
Michelle L Tomsho
Robert L Suddith
Robert J Klimchak
Andrew Stuart Janoff
Sharma R Minchey
Marc J Ostro
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of NO961779L publication Critical patent/NO961779L/no
Publication of NO961779D0 publication Critical patent/NO961779D0/no
Publication of NO312810B1 publication Critical patent/NO312810B1/no

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • A61K9/1278Post-loading, e.g. by ion or pH gradient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Saccharide Compounds (AREA)
NO19961779A 1993-11-04 1996-05-02 Multilamell¶r liposomal arachidonsyre metabolitt formuleringer og en fremgangsmåte for fremstilling av etmedikament derav NO312810B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US14789893A 1993-11-04 1993-11-04
US15285293A 1993-11-16 1993-11-16
US18008994A 1994-01-11 1994-01-11
PCT/US1994/012710 WO1995012389A1 (en) 1993-11-04 1994-11-03 Multilamellar liposomal arachidonic acid metabolite formulations

Publications (3)

Publication Number Publication Date
NO961779L NO961779L (no) 1996-05-02
NO961779D0 NO961779D0 (no) 1996-05-02
NO312810B1 true NO312810B1 (no) 2002-07-08

Family

ID=27386612

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19961779A NO312810B1 (no) 1993-11-04 1996-05-02 Multilamell¶r liposomal arachidonsyre metabolitt formuleringer og en fremgangsmåte for fremstilling av etmedikament derav
NO19961778A NO312809B1 (no) 1993-11-04 1996-05-02 Fremgangsmåter for fremstilling av en farmasöytisk sammensetning ved anvendelse av unilamell¶re liposomalearachidonsyremetabolitt formuleringer samt anvendelse derav

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO19961778A NO312809B1 (no) 1993-11-04 1996-05-02 Fremgangsmåter for fremstilling av en farmasöytisk sammensetning ved anvendelse av unilamell¶re liposomalearachidonsyremetabolitt formuleringer samt anvendelse derav

Country Status (13)

Country Link
EP (2) EP0726764B1 (ko)
JP (2) JPH09511216A (ko)
KR (2) KR100355246B1 (ko)
AT (2) ATE191141T1 (ko)
AU (2) AU687921B2 (ko)
CA (2) CA2175896A1 (ko)
DE (2) DE69423773T2 (ko)
DK (2) DK0726763T3 (ko)
ES (2) ES2136271T3 (ko)
GR (2) GR3032006T3 (ko)
NO (2) NO312810B1 (ko)
PT (1) PT726763E (ko)
WO (2) WO1995012389A1 (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6747027B1 (en) 1996-07-22 2004-06-08 Pharmacia Corporation Thiol sulfonamide metalloprotease inhibitors
ATE233552T1 (de) * 1996-07-22 2003-03-15 Monsanto Co Thiol-sulfonen als metalloproteinaseinhibitoren
US6362183B1 (en) 1997-03-04 2002-03-26 G. D. Searle & Company Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds
WO1998039316A1 (en) 1997-03-04 1998-09-11 Monsanto Company N-hydroxy 4-sulfonyl butanamide compounds
WO1998039315A1 (en) 1997-03-04 1998-09-11 Monsanto Company Aromatic sulfonyl alpha-cycloamino hydroxamic acid compounds
WO1999025687A1 (en) 1997-11-14 1999-05-27 G.D. Searle & Co. Aromatic sulfone hydroxamic acid metalloprotease inhibitor
US20010039287A1 (en) 1997-11-14 2001-11-08 Thomas E Barta Aromatic sulfone hydroxamic acid metalloprotease inhibitor
US6750228B1 (en) 1997-11-14 2004-06-15 Pharmacia Corporation Aromatic sulfone hydroxamic acid metalloprotease inhibitor
KR20010102000A (ko) 1999-02-08 2001-11-15 윌리암스 로저 에이 술파마토 히드록삼산 메탈로프로테아제 억제제
US6583299B1 (en) 1999-05-20 2003-06-24 G.D. Searle & Co. α-amino-β-sulfonyl hydroxamic acid compounds
US6683078B2 (en) 2001-07-19 2004-01-27 Pharmacia Corporation Use of sulfonyl aryl or heteroaryl hydroxamic acids and derivatives thereof as aggrecanase inhibitors
JP2003342196A (ja) * 2002-05-31 2003-12-03 Mukku:Kk 静脈注射用組成物、その製造法およびその製剤
WO2013039851A1 (en) 2011-09-12 2013-03-21 Mallinckrodt Llc Optical agents for imaging and visualization of matrix metalloproteinase enzymes
CN111053743B (zh) * 2018-10-16 2023-07-14 石药集团中奇制药技术(石家庄)有限公司 一种前列地尔脂质体及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262168A (en) * 1987-05-22 1993-11-16 The Liposome Company, Inc. Prostaglandin-lipid formulations
WO1988009170A1 (en) * 1987-05-22 1988-12-01 The Liposome Company, Inc. Prostaglandin-lipid formulations
JPH0395118A (ja) * 1989-09-07 1991-04-19 Green Cross Corp:The プロスタグランジン含有脂肪小体製剤
JPH04356421A (ja) * 1991-03-06 1992-12-10 Green Cross Corp:The プロスタグランジン類含有脂肪小体組成物
ES2128343T3 (es) * 1991-05-07 1999-05-16 Liposome Co Inc Formulaciones de prostaglandina liposomica.
JPH05139977A (ja) * 1991-05-17 1993-06-08 Green Cross Corp:The プロスタグランジン類リポソーム複合体を充填した注射器

Also Published As

Publication number Publication date
AU687921B2 (en) 1998-03-05
GR3033817T3 (en) 2000-10-31
DE69423773T2 (de) 2000-07-20
WO1995012389A1 (en) 1995-05-11
WO1995012388A1 (en) 1995-05-11
JPH09504793A (ja) 1997-05-13
KR960705544A (ko) 1996-11-08
KR100355246B1 (ko) 2003-01-06
AU8130894A (en) 1995-05-23
KR960705543A (ko) 1996-11-08
EP0726764A1 (en) 1996-08-21
DK0726764T3 (da) 1999-12-20
ATE184785T1 (de) 1999-10-15
ES2136271T3 (es) 1999-11-16
KR100355247B1 (ko) 2003-01-24
NO961778D0 (no) 1996-05-02
CA2175057A1 (en) 1995-05-11
NO312809B1 (no) 2002-07-08
EP0726763B1 (en) 2000-03-29
NO961779L (no) 1996-05-02
DE69420859D1 (de) 1999-10-28
GR3032006T3 (en) 2000-03-31
PT726763E (pt) 2000-09-29
AU8132694A (en) 1995-05-23
DK0726763T3 (da) 2000-07-10
ATE191141T1 (de) 2000-04-15
CA2175896A1 (en) 1995-05-11
DE69423773D1 (de) 2000-05-04
EP0726763A1 (en) 1996-08-21
DE69420859T2 (de) 2000-01-05
NO961779D0 (no) 1996-05-02
JPH09511216A (ja) 1997-11-11
ES2144118T3 (es) 2000-06-01
NO961778L (no) 1996-06-25
EP0726764B1 (en) 1999-09-22

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