NO309305B1 - Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater - Google Patents

Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater Download PDF

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Publication number
NO309305B1
NO309305B1 NO990814A NO990814A NO309305B1 NO 309305 B1 NO309305 B1 NO 309305B1 NO 990814 A NO990814 A NO 990814A NO 990814 A NO990814 A NO 990814A NO 309305 B1 NO309305 B1 NO 309305B1
Authority
NO
Norway
Prior art keywords
glucopyranose
deoxy
benzylidene
hydroxybenzylidene
galactopyranose
Prior art date
Application number
NO990814A
Other languages
English (en)
Norwegian (no)
Other versions
NO990814D0 (no
NO990814L (no
Inventor
Bernt Boerretzen
Vidar Moen
Rolf Olaf Larsen
Erik Olai Pettersen
Camilla Bruno Dunsaed
Geir Sagvolden
Original Assignee
Norsk Hydro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro As filed Critical Norsk Hydro As
Priority to NO990814A priority Critical patent/NO309305B1/no
Publication of NO990814D0 publication Critical patent/NO990814D0/no
Priority to EP00906781A priority patent/EP1150689A1/en
Priority to HU0105280A priority patent/HUP0105280A2/hu
Priority to AU28341/00A priority patent/AU2834100A/en
Priority to PCT/NO2000/000060 priority patent/WO2000048610A1/en
Priority to PL00350520A priority patent/PL350520A1/xx
Priority to BR0008302-0A priority patent/BR0008302A/pt
Priority to HU0105281A priority patent/HUP0105281A2/hu
Priority to JP2000599401A priority patent/JP2002537264A/ja
Priority to IL14489500A priority patent/IL144895A0/xx
Priority to JP2000599400A priority patent/JP2002537263A/ja
Priority to BR0008297-0A priority patent/BR0008297A/pt
Priority to CZ20012965A priority patent/CZ20012965A3/cs
Priority to CA002362306A priority patent/CA2362306A1/en
Priority to AU28342/00A priority patent/AU2834200A/en
Priority to PCT/NO2000/000059 priority patent/WO2000048609A1/en
Priority to SK1161-2001A priority patent/SK11612001A3/sk
Priority to CN00806488A priority patent/CN1347323A/zh
Priority to EP00906782A priority patent/EP1150690A1/en
Priority to SK1160-2001A priority patent/SK11602001A3/sk
Priority to MXPA01008346A priority patent/MXPA01008346A/es
Priority to PL00350519A priority patent/PL350519A1/xx
Priority to MXPA01008347A priority patent/MXPA01008347A/es
Priority to RU2001123124/15A priority patent/RU2001123124A/ru
Priority to CZ20012966A priority patent/CZ20012966A3/cs
Priority to CA002363670A priority patent/CA2363670A1/en
Priority to RU2001123035/14A priority patent/RU2001123035A/ru
Priority to CN00806338A priority patent/CN1347322A/zh
Priority to IL14489600A priority patent/IL144896A0/xx
Publication of NO990814L publication Critical patent/NO990814L/no
Publication of NO309305B1 publication Critical patent/NO309305B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO990814A 1999-02-19 1999-02-19 Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater NO309305B1 (no)

Priority Applications (29)

Application Number Priority Date Filing Date Title
NO990814A NO309305B1 (no) 1999-02-19 1999-02-19 Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater
IL14489600A IL144896A0 (en) 1999-02-19 2000-02-18 Pharmaceutical compositions comprising benzaldehyde derivatives and several such new compounds
AU28342/00A AU2834200A (en) 1999-02-19 2000-02-18 Chemical compounds
SK1161-2001A SK11612001A3 (sk) 1999-02-19 2000-02-18 Deriváty benzaldehydu vhodné ako protinádorové prostriedky
HU0105280A HUP0105280A2 (hu) 1999-02-19 2000-02-18 Benzaldehidszármazékok és gyógyászati alkalmazásuk és a vegyületeket tartalmazó gyógyszerkészítmények
PCT/NO2000/000060 WO2000048610A1 (en) 1999-02-19 2000-02-18 Chemical compounds
PL00350520A PL350520A1 (en) 1999-02-19 2000-02-18 Chemical compounds
BR0008302-0A BR0008302A (pt) 1999-02-19 2000-02-18 Uso de um derivado de benzaldeìdo, derivado de benzaldeìdo, composição farmacêutica, e, processo para a fabricação da mesma
HU0105281A HUP0105281A2 (hu) 1999-02-19 2000-02-18 Rákellenes hatású benzaldehidszármazékok és gyógyászati alkalmazásuk
JP2000599401A JP2002537264A (ja) 1999-02-19 2000-02-18 ベンズアルデヒド誘導体
IL14489500A IL144895A0 (en) 1999-02-19 2000-02-18 Pharmaceutical compositions comprising benzaldehyde derivatives and several such new compounds
JP2000599400A JP2002537263A (ja) 1999-02-19 2000-02-18 化学物質
BR0008297-0A BR0008297A (pt) 1999-02-19 2000-02-18 Uso de 4,6-o-(benzilideno-d1) -d-glucopiranose, 4,6-o-benzilideno-l-glucopiranose, e/ou 4,6-o-(benzilideno-d1) -l-glucopiranose, ou um sal farmacêutico aceitável dos mesmos, derivado de benzaldeìdo composição farmacêutica, e, processo para a fabricação da mesma
CZ20012965A CZ20012965A3 (cs) 1999-02-19 2000-02-18 Deriváty benzaldehydu vhodné jako protinádorové prostředky
CA002362306A CA2362306A1 (en) 1999-02-19 2000-02-18 Chemical compounds
EP00906781A EP1150689A1 (en) 1999-02-19 2000-02-18 Chemical compounds
PCT/NO2000/000059 WO2000048609A1 (en) 1999-02-19 2000-02-18 Chemical compounds
AU28341/00A AU2834100A (en) 1999-02-19 2000-02-18 Chemical compounds
CN00806488A CN1347323A (zh) 1999-02-19 2000-02-18 化合物
EP00906782A EP1150690A1 (en) 1999-02-19 2000-02-18 Chemical compounds
SK1160-2001A SK11602001A3 (sk) 1999-02-19 2000-02-18 Deriváty benzaldehydu vhodné ako protinádorové prostriedky
MXPA01008346A MXPA01008346A (es) 1999-02-19 2000-02-18 Compuestos quimicos.
PL00350519A PL350519A1 (en) 1999-02-19 2000-02-18 Chemical compounds
MXPA01008347A MXPA01008347A (es) 1999-02-19 2000-02-18 Compuestos quimicos.
RU2001123124/15A RU2001123124A (ru) 1999-02-19 2000-02-18 Химические соединения
CZ20012966A CZ20012966A3 (cs) 1999-02-19 2000-02-18 Deriváty benzaldehydu vhodné jako protinádorové prostředky
CA002363670A CA2363670A1 (en) 1999-02-19 2000-02-18 Chemical compounds
RU2001123035/14A RU2001123035A (ru) 1999-02-19 2000-02-18 Химические соединения
CN00806338A CN1347322A (zh) 1999-02-19 2000-02-18 化合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO990814A NO309305B1 (no) 1999-02-19 1999-02-19 Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater

Publications (3)

Publication Number Publication Date
NO990814D0 NO990814D0 (no) 1999-02-19
NO990814L NO990814L (no) 2000-08-21
NO309305B1 true NO309305B1 (no) 2001-01-15

Family

ID=19902986

Family Applications (1)

Application Number Title Priority Date Filing Date
NO990814A NO309305B1 (no) 1999-02-19 1999-02-19 Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater

Country Status (15)

Country Link
EP (2) EP1150690A1 (es)
JP (2) JP2002537263A (es)
CN (2) CN1347323A (es)
AU (2) AU2834200A (es)
BR (2) BR0008302A (es)
CA (2) CA2362306A1 (es)
CZ (2) CZ20012965A3 (es)
HU (2) HUP0105281A2 (es)
IL (2) IL144895A0 (es)
MX (2) MXPA01008346A (es)
NO (1) NO309305B1 (es)
PL (2) PL350519A1 (es)
RU (2) RU2001123035A (es)
SK (2) SK11602001A3 (es)
WO (2) WO2000048609A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002096921A1 (fr) * 2001-05-30 2002-12-05 Nisshin Seifun Group Inc. Nouveau derive glucose induisant l'apoptose, procede de production et utilisation comme medicament
DE10261807A1 (de) 2002-12-19 2004-07-01 Turicum Drug Development Ag Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel
CN102134232B (zh) * 2005-07-26 2012-11-21 奈科明有限责任公司 同位素取代的质子泵抑制剂
AR054583A1 (es) * 2005-07-26 2007-06-27 Altana Pharma Ag Pantoprazol isotopicamente sustituido
WO2007041630A1 (en) * 2005-10-06 2007-04-12 Auspex Pharmaceuticals, Inc. Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties
CN101157711B (zh) * 2007-09-28 2010-12-08 西安交通大学 一种具有抗肿瘤活性的化合物及其用途
MX339451B (es) * 2008-04-03 2016-05-27 Cognate 3 Llc Composiciones y metodos para inmunoterapia.
CN101735284B (zh) * 2008-11-24 2012-05-23 上海医药工业研究院 一种4,6-o-苄叉-d-吡喃葡萄糖的制备方法
CN114366741A (zh) 2013-12-03 2022-04-19 细胞内治疗公司 新方法
US10077267B2 (en) 2014-04-04 2018-09-18 Intra-Cellular Therapies, Inc. Organic compounds
JP6898072B2 (ja) * 2015-08-27 2021-07-07 秀行 佐谷 14−3−3タンパク質活性調節剤
ES2879888T3 (es) 2016-03-25 2021-11-23 Intra Cellular Therapies Inc Compuestos orgánicos y su uso en el tratamiento o prevención de trastornos del sistema nervioso central
JP7013454B2 (ja) 2016-10-12 2022-02-15 イントラ-セルラー・セラピーズ・インコーポレイテッド アモルファス固体分散体
BR112019019875A2 (pt) 2017-03-24 2020-04-22 Intra Cellular Therapies Inc novas composições e métodos
BR112021003655A2 (pt) 2018-08-31 2021-05-18 Intra-Cellular Therapies, Inc. métodos novos
US10695345B2 (en) 2018-08-31 2020-06-30 Intra-Cellular Therapies, Inc. Pharmaceutical capsule compositions comprising lumateperone mono-tosylate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB811510A (en) * 1954-12-20 1959-04-08 Gyogyszeripari Ki New nitrogen-containing derivatives of polyhydroxy compounds and process for the preparation thereof
JPS6112623A (ja) * 1984-06-28 1986-01-21 Kaken Pharmaceut Co Ltd エンケフアリナ−ゼ阻害剤
JPS6256423A (ja) * 1985-09-06 1987-03-12 Kaken Pharmaceut Co Ltd 悪液質治療改善剤
GB8705780D0 (en) * 1987-03-11 1987-04-15 Norsk Hydro As Anticancer compounds
JPH07145191A (ja) * 1993-11-24 1995-06-06 Japan Tobacco Inc ガラクトシルホスフォネート誘導体

Also Published As

Publication number Publication date
HUP0105280A2 (hu) 2002-04-29
JP2002537263A (ja) 2002-11-05
NO990814D0 (no) 1999-02-19
IL144895A0 (en) 2002-06-30
MXPA01008346A (es) 2003-06-06
RU2001123124A (ru) 2004-02-20
CA2363670A1 (en) 2000-08-24
CN1347323A (zh) 2002-05-01
MXPA01008347A (es) 2004-03-10
PL350519A1 (en) 2002-12-16
IL144896A0 (en) 2002-06-30
WO2000048610A1 (en) 2000-08-24
CN1347322A (zh) 2002-05-01
CA2362306A1 (en) 2000-08-24
AU2834200A (en) 2000-09-04
WO2000048609A1 (en) 2000-08-24
HUP0105281A2 (hu) 2002-05-29
AU2834100A (en) 2000-09-04
RU2001123035A (ru) 2004-03-20
NO990814L (no) 2000-08-21
CZ20012965A3 (cs) 2002-03-13
JP2002537264A (ja) 2002-11-05
PL350520A1 (en) 2002-12-16
BR0008302A (pt) 2002-08-27
SK11612001A3 (sk) 2002-04-04
CZ20012966A3 (cs) 2002-03-13
SK11602001A3 (sk) 2002-02-05
EP1150690A1 (en) 2001-11-07
BR0008297A (pt) 2002-05-28
EP1150689A1 (en) 2001-11-07

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