NO308856B1 - Dermatansulfater og salter av disse - Google Patents

Dermatansulfater og salter av disse

Info

Publication number
NO308856B1
NO308856B1 NO952137A NO952137A NO308856B1 NO 308856 B1 NO308856 B1 NO 308856B1 NO 952137 A NO952137 A NO 952137A NO 952137 A NO952137 A NO 952137A NO 308856 B1 NO308856 B1 NO 308856B1
Authority
NO
Norway
Prior art keywords
agents
salts
dermatane
sulphates
combined
Prior art date
Application number
NO952137A
Other languages
English (en)
Norwegian (no)
Other versions
NO952137L (no
NO952137D0 (no
Inventor
Akikazu Takada
Junichi Onaya
Mikio Arai
Satoshi Miyauchi
Mamoru Kyogashima
Keiichi Yoshida
Original Assignee
Seikagaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Co Ltd
Publication of NO952137D0 publication Critical patent/NO952137D0/no
Publication of NO952137L publication Critical patent/NO952137L/no
Publication of NO308856B1 publication Critical patent/NO308856B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
NO952137A 1993-09-30 1995-05-30 Dermatansulfater og salter av disse NO308856B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26975893 1993-09-30
PCT/JP1994/001643 WO1995009188A1 (fr) 1993-09-30 1994-09-30 Antithrombotique

Publications (3)

Publication Number Publication Date
NO952137D0 NO952137D0 (no) 1995-05-30
NO952137L NO952137L (no) 1995-07-26
NO308856B1 true NO308856B1 (no) 2000-11-06

Family

ID=17476745

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952137A NO308856B1 (no) 1993-09-30 1995-05-30 Dermatansulfater og salter av disse

Country Status (17)

Country Link
US (1) US5801162A (de)
EP (2) EP0671414B1 (de)
JP (1) JP3813169B2 (de)
KR (1) KR950704362A (de)
CN (1) CN1115182A (de)
AT (1) ATE211487T1 (de)
CA (1) CA2150552C (de)
DE (1) DE69429576T2 (de)
DK (1) DK0671414T3 (de)
ES (1) ES2173124T3 (de)
FI (1) FI952593A (de)
HU (1) HU219339B (de)
NO (1) NO308856B1 (de)
PL (2) PL177218B1 (de)
RU (1) RU2153506C2 (de)
SG (1) SG67928A1 (de)
WO (1) WO1995009188A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1274351B (it) * 1994-10-06 1997-07-17 Alfa Wassermann Spa Uso di alcuni glicosaminoglicani nella dialisi peritoneale.
CA2232527C (en) * 1995-09-19 2008-09-02 Seikagaku Corporation Anti-inflammatory agent
US6413931B1 (en) 1999-05-10 2002-07-02 The Texas A&M University System Peptide inhibitor of fibrinogen blood clotting
JP2001151680A (ja) * 1999-11-24 2001-06-05 Seikagaku Kogyo Co Ltd 鎮痒剤
JP2001187740A (ja) * 2000-01-05 2001-07-10 Seikagaku Kogyo Co Ltd 創傷治療剤
JP4633232B2 (ja) * 2000-06-22 2011-02-16 生化学工業株式会社 成長因子誘導剤
JP2002080371A (ja) * 2000-06-23 2002-03-19 Seikagaku Kogyo Co Ltd プラスミノーゲンアクチベーター活性促進剤
CA2493509C (en) * 2002-06-03 2010-03-09 Massachusetts Institute Of Technology Rationally designed polysaccharide lyases derived from chondroitinase b
CN100384884C (zh) * 2006-05-29 2008-04-30 南京健友生物化学制药有限公司 肝素钠副产物中分离提纯硫酸皮肤素和低分子硫酸乙酰肝素的方法
JP4524296B2 (ja) * 2007-03-30 2010-08-11 生化学工業株式会社 発毛促進剤
JP4881246B2 (ja) * 2007-07-13 2012-02-22 生化学工業株式会社 発毛効果増強剤
IT1401253B1 (it) * 2010-04-23 2013-07-18 Uni Degli Studi Carlo Bo Urbino Uso del sulodexide per la riduzione delle metalloproteinasi di matrice.
WO2013006906A1 (en) * 2011-07-11 2013-01-17 Commonwealth Scientific And Industrial Research Organisation Dermatan sulphate, pharmaceutical compositions and process for producing same
CN109596742B (zh) * 2018-12-25 2022-04-26 深圳市格利科生物科技有限公司 一种检测硫酸乙酰肝素成品中主要成分含量的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2535324A1 (fr) * 1982-10-27 1984-05-04 Choay Sa Station perfectionnee pour l'epuration d'eaux usees
DE3382389D1 (de) * 1982-12-14 1991-10-02 South African Inventions Plasminogenaktivator.
JPS59138202A (ja) * 1983-01-27 1984-08-08 Rikagaku Kenkyusho 新規な硫酸化アミノ糖含有多糖及びその製造法
IT1208509B (it) * 1985-03-13 1989-07-10 Mediolanum Farmaceutici Srl Processo per la produzione di eparan solfato e dermatan solfato naturali sostanzialmente puri eloro impiego farmaceutico.
DE3512909A1 (de) * 1985-04-11 1986-10-23 Behringwerke Ag, 3550 Marburg Verfahren zur bestimmung von plasminogenaktivatoren (pa)
IT1214609B (it) * 1985-05-17 1990-01-18 Opocrin Spa Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono.
FR2584728B1 (fr) * 1985-07-12 1987-11-20 Choay Sa Procede de sulfatation de glycosaminoglycanes et de leurs fragments
IT1189085B (it) * 1986-03-25 1988-01-28 Mediolanum Farmaceutici Srl Processo per la preparazione di dermatan solfato ad alta purezza e composizioni farmaceutiche che lo contengono
JPH069042B2 (ja) * 1986-09-10 1994-02-02 日本電気株式会社 共用記憶媒体の順次アクセス制御装置
JP2667469B2 (ja) * 1988-10-06 1997-10-27 日本放送協会 撮像管用偏向ヨーク
DK0421508T3 (da) * 1989-10-04 1994-04-11 Akzo Nobel Nv Sulfateret glycosaminoglycuronan med antithrombotisk aktivitet
US5118793A (en) * 1989-10-20 1992-06-02 Washington University Modified heparin cofactor II
US5382570A (en) * 1990-04-23 1995-01-17 Akzo, N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
FR2663639B1 (fr) * 1990-06-26 1994-03-18 Rhone Poulenc Sante Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.
EP0509086B1 (de) * 1990-11-05 1995-04-12 Dade Produktions AG Verfahren zur bestimmung der konzentration von antikoagulantien
IT1245761B (it) * 1991-01-30 1994-10-14 Alfa Wassermann Spa Formulazioni farmaceutiche contenenti glicosaminoglicani assorbibili per via orale.
IT1251183B (it) * 1991-08-28 1995-05-04 Opocrin Spa Dermatan solfato ad alto titolo, dotato di elevata attivita' trombolitica, e forme farmaceutiche che lo contengono.

Also Published As

Publication number Publication date
PL177218B1 (pl) 1999-10-29
FI952593A (fi) 1995-07-28
RU95112534A (ru) 1997-03-20
PL309218A1 (en) 1995-10-02
EP0671414A4 (de) 1995-11-15
SG67928A1 (en) 1999-10-19
NO952137L (no) 1995-07-26
ATE211487T1 (de) 2002-01-15
US5801162A (en) 1998-09-01
JP3813169B2 (ja) 2006-08-23
EP0671414A1 (de) 1995-09-13
CN1115182A (zh) 1996-01-17
HU219339B (en) 2001-03-28
EP1125977A1 (de) 2001-08-22
AU699371B2 (en) 1998-12-03
WO1995009188A1 (fr) 1995-04-06
NO952137D0 (no) 1995-05-30
DK0671414T3 (da) 2002-04-22
PL177245B1 (pl) 1999-10-29
KR950704362A (ko) 1995-11-20
RU2153506C2 (ru) 2000-07-27
FI952593A0 (fi) 1995-05-29
ES2173124T3 (es) 2002-10-16
HU9501542D0 (en) 1995-07-28
CA2150552C (en) 1999-12-21
DE69429576D1 (de) 2002-02-07
HUT73245A (en) 1996-07-29
AU7708594A (en) 1995-04-18
EP0671414B1 (de) 2002-01-02
DE69429576T2 (de) 2002-08-22

Similar Documents

Publication Publication Date Title
NO308856B1 (no) Dermatansulfater og salter av disse
SE9404196D0 (sv) New antithrombotic formulation
BR9811825A (pt) Uso de lactobacillus para redução do nìvel de fibrinogênio no sangue
SE8903914D0 (sv) Oral composition for the treatment of inflammatory bowel diseases
SE8803472A (de)
PL316449A1 (en) Combinations of thrombolytically active proteins and coagulants and their application
DE69116380T2 (de) Pharmazeutische zubereitung zur behandlung verlängerter gerinnungszeit
NO994165L (no) Anvendelse av deskarboetoksyloratadin for fremstilling av et medikament for behandling av urininkontinens, reisesyke og svimmelhet
DK0856312T3 (da) Anvendelse af trospiumchlorid til fremstilling af et lægemiddel til behandling af blæresygdomme
WO2004037208A3 (en) Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
CA2033249A1 (en) Cytostatic or cytotoxic combination of active substances for use in therapeutic procedures
MD1521F2 (en) Methods of thrombus forming inhibition, methods of treatment of thrombotic states, pharmaceutical compositions and kit for treatment of thrombotic states
CO5280202A1 (es) Metodos de tratamiento y metodos de rastreo de farmacos
PL354961A1 (en) Prevention and treatment of diseases associated with blood coagulation
Francis et al. Thrombin activity associated with indwelling central venous catheters
PT711163E (pt) Utilizacao de benzidamina no tratamento de estados patologicos provocados por tnf
RU95116161A (ru) Способ лечения синдрома диссеминированного внутрисосудистого микротромбоза при тяжелой изолированной и сочетанной черепно-мозговой травме
SCHULMAN Optimal duration of anticoagulation therapy after venous thromboembolism
RU97107531A (ru) Способ лечения послеоперационных остаточных костно-мягкотканных полостей у больных с гнойными заболеваниями длинных трубчатых костей
RU97119966A (ru) Способ лечения жировой эмболии при переломах длинных трубчатых костей конечностей
ITMI910114U1 (it) Struttura di calza ortopedica in particolare per la cura e la prevenzi one del valgismo dell'alluce
IT8819879A0 (it) Composizioni farmaceutiche atte all'impiego nella terapia dell'ipotensione arteriosa.

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN MARCH 2002