NO308213B1 - Substituerte indanylidinacetylguanidiner, deres anvendelse og medikamenter inneholdende forbindelsene - Google Patents

Substituerte indanylidinacetylguanidiner, deres anvendelse og medikamenter inneholdende forbindelsene

Info

Publication number
NO308213B1
NO308213B1 NO973486A NO973486A NO308213B1 NO 308213 B1 NO308213 B1 NO 308213B1 NO 973486 A NO973486 A NO 973486A NO 973486 A NO973486 A NO 973486A NO 308213 B1 NO308213 B1 NO 308213B1
Authority
NO
Norway
Prior art keywords
indanylidinacetylguanidines
substituted
compounds
drugs containing
drugs
Prior art date
Application number
NO973486A
Other languages
English (en)
Norwegian (no)
Other versions
NO973486D0 (no
NO973486L (no
Inventor
Nirogi Venkata Sat Ramakrishna
Arun Kumar Jain
Bansi Lal
Roa Venkata Satya Ve Vadlamudi
Anil Vasantrao Ghate
Ravindra Dattatraya Gupte
Andreas Weichert
Jan-Robert Schwark
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO973486D0 publication Critical patent/NO973486D0/no
Publication of NO973486L publication Critical patent/NO973486L/no
Publication of NO308213B1 publication Critical patent/NO308213B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/38Amides of thiocarboxylic acids
    • C07C327/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C327/54Y being a hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO973486A 1996-07-30 1997-07-29 Substituerte indanylidinacetylguanidiner, deres anvendelse og medikamenter inneholdende forbindelsene NO308213B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96112275A EP0837055A1 (en) 1996-07-30 1996-07-30 Substituted Indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic and medicaments containing them

Publications (3)

Publication Number Publication Date
NO973486D0 NO973486D0 (no) 1997-07-29
NO973486L NO973486L (no) 1998-02-02
NO308213B1 true NO308213B1 (no) 2000-08-14

Family

ID=8223055

Family Applications (1)

Application Number Title Priority Date Filing Date
NO973486A NO308213B1 (no) 1996-07-30 1997-07-29 Substituerte indanylidinacetylguanidiner, deres anvendelse og medikamenter inneholdende forbindelsene

Country Status (29)

Country Link
US (1) US5900436A (cs)
EP (2) EP0837055A1 (cs)
JP (1) JP4039589B2 (cs)
KR (1) KR980009236A (cs)
CN (1) CN1064351C (cs)
AR (1) AR008095A1 (cs)
AT (1) ATE207888T1 (cs)
AU (1) AU715187B2 (cs)
BR (1) BR9704131A (cs)
CA (1) CA2211982C (cs)
CZ (1) CZ241197A3 (cs)
DE (1) DE69707777T2 (cs)
DK (1) DK0822182T3 (cs)
ES (1) ES2164283T3 (cs)
HR (1) HRP970424B1 (cs)
HU (1) HUP9701316A3 (cs)
ID (1) ID17565A (cs)
IL (1) IL121407A0 (cs)
MX (1) MX9705737A (cs)
NO (1) NO308213B1 (cs)
NZ (1) NZ328440A (cs)
PL (1) PL321392A1 (cs)
PT (1) PT822182E (cs)
RU (1) RU2176638C2 (cs)
SI (1) SI0822182T1 (cs)
SK (1) SK282128B6 (cs)
TR (1) TR199700704A2 (cs)
TW (1) TW445251B (cs)
ZA (1) ZA976735B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018129556A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
MX2011007024A (es) 2008-12-31 2011-09-27 Aedelyx Inc Compuestos y metodos para inhibir el antiporte mediado por intercambiador de iones de sodio/iones de hidrogeno (nhe) en el tratamiento de trastornos asociados con retencion de fluido o sobrecarga de sal y trastornos del tracto gastrointestinal.
GB0916163D0 (en) * 2009-09-15 2009-10-28 Shire Llc Prodrugs of guanfacine
KR20250026881A (ko) 2013-04-12 2025-02-25 알데릭스, 인코포레이티드 Nhe3-결합 화합물 및 포스페이트 수송을 저해하는 방법
KR20190128626A (ko) 2017-01-09 2019-11-18 알데릭스, 인코포레이티드 Nhe-매개 역수송의 저해제
CN118221656A (zh) 2017-01-09 2024-06-21 阿德利克斯股份有限公司 可用于治疗胃肠道病症的化合物
US20200368223A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Methods for inhibiting phosphate transport
CN116492469A (zh) * 2023-05-22 2023-07-28 遵义医科大学附属医院 一种通道阻滞剂在制备治疗和/或预防肝纤维疾病药物中的应用
CN119118881A (zh) * 2024-07-25 2024-12-13 中国农业大学 含胍基的5-氯茚满化合物及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
DE4421536A1 (de) * 1994-06-20 1995-12-21 Hoechst Ag Perfluoralkylgruppen tragende phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
SI0738712T1 (en) * 1995-04-18 1999-12-31 Hoechst Aktiengesellschaft Anti-arrhythmic and cardioprotective substituted indenoylguanidines

Also Published As

Publication number Publication date
ATE207888T1 (de) 2001-11-15
NO973486D0 (no) 1997-07-29
EP0822182B1 (en) 2001-10-31
SI0822182T1 (en) 2002-04-30
DE69707777T2 (de) 2003-01-16
HRP970424B1 (en) 2002-06-30
HRP970424A2 (en) 1998-06-30
CZ241197A3 (cs) 1998-02-18
KR980009236A (ko) 1998-04-30
US5900436A (en) 1999-05-04
IL121407A0 (en) 1998-01-04
TR199700704A2 (xx) 1998-02-21
JPH1129545A (ja) 1999-02-02
EP0822182A1 (en) 1998-02-04
AR008095A1 (es) 1999-12-09
NO973486L (no) 1998-02-02
CA2211982C (en) 2007-09-18
CN1064351C (zh) 2001-04-11
SK103497A3 (en) 1998-02-04
DK0822182T3 (da) 2002-02-25
HU9701316D0 (en) 1997-09-29
AU3155497A (en) 1998-02-05
ES2164283T3 (es) 2002-02-16
MX9705737A (es) 1998-02-28
BR9704131A (pt) 1998-12-29
ID17565A (id) 1998-01-08
NZ328440A (en) 1997-11-24
PT822182E (pt) 2002-03-28
HUP9701316A2 (hu) 1998-03-02
PL321392A1 (en) 1998-02-02
ZA976735B (en) 1998-01-30
JP4039589B2 (ja) 2008-01-30
SK282128B6 (sk) 2001-11-06
EP0837055A1 (en) 1998-04-22
CN1172104A (zh) 1998-02-04
HUP9701316A3 (en) 1998-07-28
AU715187B2 (en) 2000-01-20
CA2211982A1 (en) 1998-01-30
TW445251B (en) 2001-07-11
DE69707777D1 (de) 2001-12-06
RU2176638C2 (ru) 2001-12-10

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