NO307999B1 - Salter av 3-(2-(4-(4-amino-imino-metyl)-fenyl)-4-metyl-2,5- diokso-imidazolidin-1-yl(-acetylamino)-3-fenyl-propionsyre- etylestere, anvendelse av forbindelsene samt farmasøytiske preparater inneholdende disse - Google Patents
Salter av 3-(2-(4-(4-amino-imino-metyl)-fenyl)-4-metyl-2,5- diokso-imidazolidin-1-yl(-acetylamino)-3-fenyl-propionsyre- etylestere, anvendelse av forbindelsene samt farmasøytiske preparater inneholdende disseInfo
- Publication number
- NO307999B1 NO307999B1 NO972506A NO972506A NO307999B1 NO 307999 B1 NO307999 B1 NO 307999B1 NO 972506 A NO972506 A NO 972506A NO 972506 A NO972506 A NO 972506A NO 307999 B1 NO307999 B1 NO 307999B1
- Authority
- NO
- Norway
- Prior art keywords
- phenyl
- methyl
- imidazolidin
- acetylamino
- dioxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19622489A DE19622489A1 (de) | 1996-06-05 | 1996-06-05 | Salze des 3-(2-(4-(4-(Amino-imino-methyl)-phenyl)-4- methyl-2,5-dioxo-imidazolidin-1-yl)-acetylamino)-3- phenyl-propionsäure-ethylesters |
Publications (3)
Publication Number | Publication Date |
---|---|
NO972506D0 NO972506D0 (no) | 1997-06-02 |
NO972506L NO972506L (no) | 1997-12-08 |
NO307999B1 true NO307999B1 (no) | 2000-07-03 |
Family
ID=7796165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO972506A NO307999B1 (no) | 1996-06-05 | 1997-06-02 | Salter av 3-(2-(4-(4-amino-imino-metyl)-fenyl)-4-metyl-2,5- diokso-imidazolidin-1-yl(-acetylamino)-3-fenyl-propionsyre- etylestere, anvendelse av forbindelsene samt farmasøytiske preparater inneholdende disse |
Country Status (24)
Country | Link |
---|---|
US (1) | US6294562B1 (no) |
EP (1) | EP0811616B1 (no) |
JP (1) | JP4249277B2 (no) |
KR (1) | KR980002029A (no) |
CN (1) | CN1104420C (no) |
AR (1) | AR008993A1 (no) |
AT (1) | ATE294783T1 (no) |
AU (1) | AU717106B2 (no) |
BR (1) | BR9703459A (no) |
CA (1) | CA2206748C (no) |
CZ (1) | CZ292672B6 (no) |
DE (2) | DE19622489A1 (no) |
ES (1) | ES2241016T3 (no) |
HK (1) | HK1006359A1 (no) |
HR (1) | HRP970309B1 (no) |
HU (1) | HUP9700998A3 (no) |
IL (1) | IL120984A (no) |
MX (1) | MX9704128A (no) |
NO (1) | NO307999B1 (no) |
PL (1) | PL320355A1 (no) |
RU (1) | RU2174119C2 (no) |
SK (1) | SK70897A3 (no) |
TR (1) | TR199700457A2 (no) |
ZA (1) | ZA974912B (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19647380A1 (de) * | 1996-11-15 | 1998-05-20 | Hoechst Ag | 5-Ring-Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten |
US7544681B2 (en) | 2001-09-27 | 2009-06-09 | Ramot At Tel Aviv University Ltd. | Conjugated psychotropic drugs and uses thereof |
AU2004277464B2 (en) * | 2003-10-02 | 2010-07-08 | Pharmacia & Upjohn Company Llc | Salts and polymorphs of a pyrrole-substituted indolinone compound |
JP5284779B2 (ja) * | 2005-06-07 | 2013-09-11 | ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド | コンジュゲート化された向精神薬の新規な塩およびその調製方法 |
AU2007274583B2 (en) | 2006-07-17 | 2012-11-01 | Bar-Ilan University | Conjugates comprising a psychotropic drug or a GABA agonist and an organic acid and their use in treating pain and other CNS disorders |
WO2009101616A1 (en) | 2008-02-11 | 2009-08-20 | Ramot At Tel Aviv University Ltd. | Novel conjugates for treating neurodegenerative diseases and disorders |
US8975251B2 (en) | 2009-12-09 | 2015-03-10 | Bar-Ilan University | Methods of improving cognitive functions |
CN102858345A (zh) | 2010-02-24 | 2013-01-02 | 雷蒙特亚特特拉维夫大学有限公司 | 奋乃静-gaba的三甲磺酸盐的晶型及其制备方法 |
WO2012038963A1 (en) | 2010-09-22 | 2012-03-29 | Ramot At Tel-Aviv University Ltd. | An acid addition salt of a nortriptyline-gaba conjugate and a process of preparing same |
CN112312910A (zh) | 2018-04-12 | 2021-02-02 | 莫菲克医疗股份有限公司 | 人整合素α4β7拮抗剂 |
TW202332675A (zh) | 2019-10-16 | 2023-08-16 | 美商莫菲克醫療股份有限公司 | 抑制人類整合素α4β7 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4126277A1 (de) * | 1991-08-08 | 1993-02-11 | Cassella Ag | Hydantoinderivate |
DE4213634A1 (de) * | 1992-04-24 | 1993-10-28 | Cassella Ag | 2,4-Dioxo-imidazolidin-Derivate |
DE4224414A1 (de) | 1992-07-24 | 1994-01-27 | Cassella Ag | Phenylimidazolidin-derivate, ihre Herstellung und ihre Verwendung |
DE4308034A1 (de) | 1993-03-13 | 1994-09-15 | Cassella Ag | Neue Heterocyclen, ihre Herstellung und ihre Verwendung |
DE4309867A1 (de) | 1993-03-26 | 1994-09-29 | Cassella Ag | Neue Harnstoffderivate, ihre Herstellung und Verwendung |
DE4427979A1 (de) | 1993-11-15 | 1996-02-15 | Cassella Ag | Substituierte 5-Ring-Heterocyclen, ihre Herstellung und ihre Verwendung |
DE19515177A1 (de) * | 1995-04-28 | 1996-10-31 | Cassella Ag | Hydantoinderivate als Zwischenprodukte für pharmazeutische Wirkstoffe |
-
1996
- 1996-06-05 DE DE19622489A patent/DE19622489A1/de not_active Withdrawn
-
1997
- 1997-05-28 EP EP97108569A patent/EP0811616B1/de not_active Expired - Lifetime
- 1997-05-28 DE DE59712294T patent/DE59712294D1/de not_active Expired - Lifetime
- 1997-05-28 ES ES97108569T patent/ES2241016T3/es not_active Expired - Lifetime
- 1997-05-28 AT AT97108569T patent/ATE294783T1/de not_active IP Right Cessation
- 1997-06-02 NO NO972506A patent/NO307999B1/no not_active IP Right Cessation
- 1997-06-03 IL IL12098497A patent/IL120984A/xx not_active IP Right Cessation
- 1997-06-03 JP JP14561797A patent/JP4249277B2/ja not_active Expired - Fee Related
- 1997-06-03 TR TR97/00457A patent/TR199700457A2/xx unknown
- 1997-06-03 AR ARP970102405A patent/AR008993A1/es unknown
- 1997-06-03 AU AU24674/97A patent/AU717106B2/en not_active Ceased
- 1997-06-03 CN CN97105465A patent/CN1104420C/zh not_active Expired - Fee Related
- 1997-06-04 ZA ZA9704912A patent/ZA974912B/xx unknown
- 1997-06-04 HR HR970309A patent/HRP970309B1/xx not_active IP Right Cessation
- 1997-06-04 PL PL97320355A patent/PL320355A1/xx unknown
- 1997-06-04 SK SK708-97A patent/SK70897A3/sk unknown
- 1997-06-04 CA CA002206748A patent/CA2206748C/en not_active Expired - Fee Related
- 1997-06-04 CZ CZ19971729A patent/CZ292672B6/cs unknown
- 1997-06-04 HU HU9700998A patent/HUP9700998A3/hu unknown
- 1997-06-04 KR KR1019970022995A patent/KR980002029A/ko not_active Application Discontinuation
- 1997-06-04 MX MX9704128A patent/MX9704128A/es not_active IP Right Cessation
- 1997-06-05 RU RU97109041/04A patent/RU2174119C2/ru not_active IP Right Cessation
- 1997-06-05 BR BR9703459A patent/BR9703459A/pt not_active IP Right Cessation
-
1998
- 1998-06-18 HK HK98105621A patent/HK1006359A1/xx not_active IP Right Cessation
-
1999
- 1999-04-29 US US09/301,907 patent/US6294562B1/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI933804A0 (fi) | Monohydrat av 5-(2-(4-(1,2-bensisotiazol-3-yl)-1-piperazinyl)etyl-6-klor-1,3-dihydro-2h-indol-2-onkhydroklorid | |
NO903925L (no) | Fremgangsmaate for fremstilling av 3-(1-substituert-4-piperazinyl)-1h-indazoler samt anvendelse som legemidler. | |
DE58904042D1 (en) | Substituierte 4-(chinolin-2-yl-methoxy)phenyl-essigsaeure-derivate. | |
CL2003002336A1 (es) | Procedimiento de preparacion del acido (e)-(6-{2[4-(4-fluorofenil)-6-isopropil-2-[n-metil-n-metilsulfonil-amino]pirimidina-5-il]vinilo}-(4r,6s)-diol-4-il)-acetico o su sal, los intermediarios que se usan y la preparacion de uno de ellos. | |
NO307999B1 (no) | Salter av 3-(2-(4-(4-amino-imino-metyl)-fenyl)-4-metyl-2,5- diokso-imidazolidin-1-yl(-acetylamino)-3-fenyl-propionsyre- etylestere, anvendelse av forbindelsene samt farmasøytiske preparater inneholdende disse | |
DK46489A (da) | Anvendelse af 4-(1-(2,3-dimetylfenyl)-aetyl)-1h-imidazol til fremstilling af laegemidler til perioperativ anvendelse | |
ATE196141T1 (de) | Heterocyclisch substituierte phenyl-cyclohexan- carbonsäurederivate als angiotensin ii antagonisten | |
FI960278A0 (fi) | Anataasititaanidioksidin valmistusmenetelmä | |
NO932791L (no) | Fremgangsmaate for fremstilling av titandioksyd | |
NO893270D0 (no) | Fremgangsmaate for fremstilling av terapeutisk aktive tetrahydropyridineddiksyrederivater. | |
HUP0102401A3 (en) | Novel intermediates and processes for the preparation of optically active octanoic acid derivatives | |
DE59709030D1 (de) | Verwendung von Reinigungsmitteln enthaltend 3-(N-Butylacetamino)-propionsäureethylester als insektiziden Wirstoff. | |
AU5647199A (en) | Carboxylic acid derivatives and drugs containing the same as the active ingredient | |
NO951147D0 (no) | Substituerte heterocykliske karboksylsyreamidestere, deres fremstilling og deres anvendelse som legemiddel | |
NO930829D0 (no) | Fremgangsmaate for fremstilling av klavulansyresalter | |
HUP9900344A3 (en) | Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof | |
EE9700186A (et) | Klavulaanhappe soolad | |
AU7550391A (en) | Pharmaceutical aqueous solution of 4-{2-(benzolsulphonylamino)-ethyl}-phenoxyacetic acid | |
DK0888340T3 (da) | 4-(benzo-1,3-dioxolyl)-pyrrolidin-3-carboxylsyre-derivater som antagonister for enodthelin | |
HUP9800511A3 (en) | Phosphorylized derivatives of 4-{4-[4-(hydroxy-diphenyl)-1-pipe | |
NO971583L (no) | Fremgangsmåte for fremstilling av 2-£2-£4-£4-klorfenyl)fenylmetyl|-1-piperazinyl|etoksy|eddiksyre og dens salter | |
NO920313D0 (no) | Fremgangsmaate for fremstilling av rasemisk og optisk aktiv 1,2,3,4-tetrahydroisokinolin-3-karbonsyre samt forprodukter derav | |
AU6471800A (en) | 4-(substituted phenyl)-5-halopyrimidine derivatives and herbicides containing the same as the active ingredient | |
ATE289195T1 (de) | Verwendung von substituierten 4-amino-1- phenylbutan-2-ol-verbindungen als arzneimittel | |
NO981499D0 (no) | Fremgangsmåte for fremstilling av titandioksyd |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |