NO972506L - Salter av 3-(2-(4(-amino-imino-metyl)-fenyl)-4-metyl-2,5-diokso-imidazolidin-1-yl(-acetylamino)-3-fenyl-propionsyre-etylestere - Google Patents

Salter av 3-(2-(4(-amino-imino-metyl)-fenyl)-4-metyl-2,5-diokso-imidazolidin-1-yl(-acetylamino)-3-fenyl-propionsyre-etylestere

Info

Publication number
NO972506L
NO972506L NO972506A NO972506A NO972506L NO 972506 L NO972506 L NO 972506L NO 972506 A NO972506 A NO 972506A NO 972506 A NO972506 A NO 972506A NO 972506 L NO972506 L NO 972506L
Authority
NO
Norway
Prior art keywords
phenyl
methyl
imidazolidin
acetylamino
dioxo
Prior art date
Application number
NO972506A
Other languages
English (en)
Other versions
NO307999B1 (no
NO972506D0 (no
Inventor
Hans Ulrich Stilz
Gerhard Beck
Manfred Radau
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO972506D0 publication Critical patent/NO972506D0/no
Publication of NO972506L publication Critical patent/NO972506L/no
Publication of NO307999B1 publication Critical patent/NO307999B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
NO972506A 1996-06-05 1997-06-02 Salter av 3-(2-(4-(4-amino-imino-metyl)-fenyl)-4-metyl-2,5- diokso-imidazolidin-1-yl(-acetylamino)-3-fenyl-propionsyre- etylestere, anvendelse av forbindelsene samt farmasøytiske preparater inneholdende disse NO307999B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19622489A DE19622489A1 (de) 1996-06-05 1996-06-05 Salze des 3-(2-(4-(4-(Amino-imino-methyl)-phenyl)-4- methyl-2,5-dioxo-imidazolidin-1-yl)-acetylamino)-3- phenyl-propionsäure-ethylesters

Publications (3)

Publication Number Publication Date
NO972506D0 NO972506D0 (no) 1997-06-02
NO972506L true NO972506L (no) 1997-12-08
NO307999B1 NO307999B1 (no) 2000-07-03

Family

ID=7796165

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972506A NO307999B1 (no) 1996-06-05 1997-06-02 Salter av 3-(2-(4-(4-amino-imino-metyl)-fenyl)-4-metyl-2,5- diokso-imidazolidin-1-yl(-acetylamino)-3-fenyl-propionsyre- etylestere, anvendelse av forbindelsene samt farmasøytiske preparater inneholdende disse

Country Status (24)

Country Link
US (1) US6294562B1 (no)
EP (1) EP0811616B1 (no)
JP (1) JP4249277B2 (no)
KR (1) KR980002029A (no)
CN (1) CN1104420C (no)
AR (1) AR008993A1 (no)
AT (1) ATE294783T1 (no)
AU (1) AU717106B2 (no)
BR (1) BR9703459A (no)
CA (1) CA2206748C (no)
CZ (1) CZ292672B6 (no)
DE (2) DE19622489A1 (no)
ES (1) ES2241016T3 (no)
HK (1) HK1006359A1 (no)
HR (1) HRP970309B1 (no)
HU (1) HUP9700998A3 (no)
IL (1) IL120984A (no)
MX (1) MX9704128A (no)
NO (1) NO307999B1 (no)
PL (1) PL320355A1 (no)
RU (1) RU2174119C2 (no)
SK (1) SK70897A3 (no)
TR (1) TR199700457A2 (no)
ZA (1) ZA974912B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19647380A1 (de) * 1996-11-15 1998-05-20 Hoechst Ag 5-Ring-Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten
US7544681B2 (en) 2001-09-27 2009-06-09 Ramot At Tel Aviv University Ltd. Conjugated psychotropic drugs and uses thereof
CA2540639C (en) * 2003-10-02 2010-08-31 Pharmacia & Upjohn Company Llc Salts and polymorphs of a pyrrole-substituted indolinone compound
EP1888120B1 (en) * 2005-06-07 2012-12-05 Ramot at Tel Aviv University Ltd. Novel salts of conjugated psychotropic drugs and processes of preparing same
US8222296B2 (en) 2006-07-17 2012-07-17 Ramot At Tel-Aviv University Ltd. Conjugates comprising a GABA- or glycine compound, pharmaceutical compositions and combinations thereof and their use in treating CNS disorders
WO2009101616A1 (en) 2008-02-11 2009-08-20 Ramot At Tel Aviv University Ltd. Novel conjugates for treating neurodegenerative diseases and disorders
CA2782514A1 (en) 2009-12-09 2011-06-16 Biolinerx Ltd. Methods of improving cognitive functions
JP2013520488A (ja) 2010-02-24 2013-06-06 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド ペルフェナジン−ｇａｂａのトリメシラート塩の結晶性形態物及びその製法方法
WO2012038963A1 (en) 2010-09-22 2012-03-29 Ramot At Tel-Aviv University Ltd. An acid addition salt of a nortriptyline-gaba conjugate and a process of preparing same
AR114489A1 (es) * 2018-04-12 2020-09-09 Morphic Therapeutic Inc ANTAGONISTAS DE LA INTEGRINA a4b7 HUMANA
MX2022004406A (es) 2019-10-16 2022-08-25 Morphic Therapeutic Inc INHIBICIÓN DE INTEGRINA A4ß7 HUMANA.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4126277A1 (de) * 1991-08-08 1993-02-11 Cassella Ag Hydantoinderivate
DE4213634A1 (de) * 1992-04-24 1993-10-28 Cassella Ag 2,4-Dioxo-imidazolidin-Derivate
DE4224414A1 (de) 1992-07-24 1994-01-27 Cassella Ag Phenylimidazolidin-derivate, ihre Herstellung und ihre Verwendung
DE4308034A1 (de) 1993-03-13 1994-09-15 Cassella Ag Neue Heterocyclen, ihre Herstellung und ihre Verwendung
DE4309867A1 (de) 1993-03-26 1994-09-29 Cassella Ag Neue Harnstoffderivate, ihre Herstellung und Verwendung
DE4427979A1 (de) 1993-11-15 1996-02-15 Cassella Ag Substituierte 5-Ring-Heterocyclen, ihre Herstellung und ihre Verwendung
DE19515177A1 (de) * 1995-04-28 1996-10-31 Cassella Ag Hydantoinderivate als Zwischenprodukte für pharmazeutische Wirkstoffe

Also Published As

Publication number Publication date
US6294562B1 (en) 2001-09-25
CA2206748A1 (en) 1997-12-05
CA2206748C (en) 2007-05-01
CZ292672B6 (cs) 2003-11-12
RU2174119C2 (ru) 2001-09-27
HUP9700998A3 (en) 1999-03-01
MX9704128A (es) 1997-12-31
DE59712294D1 (de) 2005-06-09
ZA974912B (en) 1997-12-05
SK70897A3 (en) 1999-05-07
PL320355A1 (en) 1997-12-08
HRP970309B1 (en) 2002-06-30
CN1174835A (zh) 1998-03-04
ATE294783T1 (de) 2005-05-15
HUP9700998A1 (hu) 1998-03-30
NO307999B1 (no) 2000-07-03
KR980002029A (ko) 1998-03-30
JPH1059948A (ja) 1998-03-03
JP4249277B2 (ja) 2009-04-02
TR199700457A2 (xx) 1997-12-21
AU717106B2 (en) 2000-03-16
HK1006359A1 (en) 1999-02-26
HRP970309A2 (en) 1998-04-30
IL120984A (en) 2001-08-26
EP0811616A1 (de) 1997-12-10
HU9700998D0 (en) 1997-07-28
DE19622489A1 (de) 1997-12-11
IL120984A0 (en) 1997-11-20
AR008993A1 (es) 2000-03-08
AU2467497A (en) 1997-12-11
CZ172997A3 (en) 1997-12-17
EP0811616B1 (de) 2005-05-04
NO972506D0 (no) 1997-06-02
ES2241016T3 (es) 2005-10-16
BR9703459A (pt) 1998-10-06
CN1104420C (zh) 2003-04-02

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