NO307256B1 - Tiadiazoler, farmasoeytisk preparat inneholdende slike forbindelser og deres anvendelse - Google Patents
Tiadiazoler, farmasoeytisk preparat inneholdende slike forbindelser og deres anvendelseInfo
- Publication number
- NO307256B1 NO307256B1 NO964773A NO964773A NO307256B1 NO 307256 B1 NO307256 B1 NO 307256B1 NO 964773 A NO964773 A NO 964773A NO 964773 A NO964773 A NO 964773A NO 307256 B1 NO307256 B1 NO 307256B1
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- hydroxyalkyl
- alkoxy
- thiadiazolyl
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000004867 thiadiazoles Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 3
- -1 nitro, carboxy Chemical group 0.000 abstract 3
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000001028 difluoromethyl group Chemical group [H]C(F)(F)* 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000001113 thiadiazolyl group Chemical group 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000006002 1,1-difluoroethyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000278 alkyl amino alkyl group Chemical group 0.000 abstract 1
- 125000004687 alkyl sulfinyl alkyl group Chemical group 0.000 abstract 1
- 125000004688 alkyl sulfonyl alkyl group Chemical group 0.000 abstract 1
- 125000006350 alkyl thio alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 125000004541 benzoxazolyl group Chemical group O1C(=NC2=C1C=CC=C2)* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
- 125000003709 fluoroalkyl group Chemical group 0.000 abstract 1
- 125000004216 fluoromethyl group Chemical group [H]C([H])(F)* 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000001786 isothiazolyl group Chemical group 0.000 abstract 1
- 125000000842 isoxazolyl group Chemical group 0.000 abstract 1
- 125000001715 oxadiazolyl group Chemical group 0.000 abstract 1
- 125000002971 oxazolyl group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 125000000335 thiazolyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/242,529 US5453433A (en) | 1994-05-13 | 1994-05-13 | Thiadiazoles and antipicornaviral compositions |
| PCT/US1995/005790 WO1995031198A1 (en) | 1994-05-13 | 1995-05-10 | Thiadiazoles and their use as antipicornaviral agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO964773L NO964773L (no) | 1996-11-11 |
| NO964773D0 NO964773D0 (no) | 1996-11-11 |
| NO307256B1 true NO307256B1 (no) | 2000-03-06 |
Family
ID=22915137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO964773A NO307256B1 (no) | 1994-05-13 | 1996-11-11 | Tiadiazoler, farmasoeytisk preparat inneholdende slike forbindelser og deres anvendelse |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US5453433A (pl) |
| EP (1) | EP0759755B1 (pl) |
| JP (1) | JP4158946B2 (pl) |
| KR (1) | KR100383495B1 (pl) |
| CN (1) | CN1095664C (pl) |
| AT (1) | ATE247112T1 (pl) |
| AU (1) | AU691923B2 (pl) |
| CA (1) | CA2190130C (pl) |
| CZ (1) | CZ289061B6 (pl) |
| DE (1) | DE69531491D1 (pl) |
| NO (1) | NO307256B1 (pl) |
| NZ (1) | NZ285910A (pl) |
| PL (1) | PL181099B1 (pl) |
| RU (1) | RU2140916C1 (pl) |
| WO (1) | WO1995031198A1 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5514679A (en) * | 1994-05-13 | 1996-05-07 | Sterling Winthrop Inc. | Therapeutic phenoxyalklpyridazines and intermediates therefor |
| AR004012A1 (es) | 1995-10-10 | 1998-09-30 | Basf Ag | Derivados de acido fenilacetico, procedimientos para su obtencion, su uso para preparar composiciones para combatir animales u hongos nocivos, lascomposiciones asi obtenidas y los procedimientos de aplicacion de dichas composiciones. |
| AUPQ105499A0 (en) | 1999-06-18 | 1999-07-08 | Biota Scientific Management Pty Ltd | Antiviral agents |
| AUPR213700A0 (en) * | 2000-12-18 | 2001-01-25 | Biota Scientific Management Pty Ltd | Antiviral agents |
| US6887462B2 (en) | 2001-04-09 | 2005-05-03 | Chiron Corporation | HSA-free formulations of interferon-beta |
| WO2003020712A1 (en) * | 2001-08-29 | 2003-03-13 | Viropharma Incorporated | Oxadiazolyl-phenoxyalkylthiadiazoles, compositions thereof and methods for their use as anti-picornaviral agents |
| CA2641616A1 (en) * | 2006-02-09 | 2007-08-23 | Schering Corporation | Pharmaceutical formulations |
| CN103102348B (zh) * | 2011-11-14 | 2016-06-08 | 上海交通大学 | 噁二唑类化合物及其制备方法、药物组合物及其用途 |
| WO2017050969A1 (en) * | 2015-09-24 | 2017-03-30 | Universite Paris Est Creteil Val De Marne | Heterocyclic ho-1 inducers, their use in the treatment of inflammatory or cardiovascular diseases and their process of preparation |
| BR112021002515A2 (pt) * | 2018-08-21 | 2021-07-27 | Kyorin Pharmaceutical Co., Ltd. | derivado de anel heteroaromático bicíclico |
| CN114014824B (zh) * | 2020-12-09 | 2023-06-13 | 上海科技大学 | 一种杂环化合物的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1437781A (en) * | 1972-04-04 | 1976-06-03 | Beecham Group Ltd | Pyridine derivatives having hypoglycaemic activity |
| NZ209209A (en) * | 1983-08-29 | 1988-02-12 | Sterling Drug Inc | Substituted phenyl-aliphatic isoxazole derivatives and pharmaceutical compositions |
| ZA858493B (en) * | 1984-11-12 | 1986-07-30 | Yamanouchi Pharma Co Ltd | Heterocyclic compounds and process of producing them |
| CA1280753C (en) * | 1985-07-02 | 1991-02-26 | Philip Michael Carabateas | Process for preparing heterocyclic substituted- phenoxyalkyl isoxazoles and-furans |
| EP0229501B1 (en) * | 1985-12-16 | 1990-12-27 | Eli Lilly And Company | Thiadiazole antiviral agents |
| JP2504438B2 (ja) * | 1986-03-25 | 1996-06-05 | 三菱化学株式会社 | チアジアゾ−ル誘導体及びこれを有効成分とする殺虫殺ダニ剤 |
| JPH07116183B2 (ja) * | 1987-03-31 | 1995-12-13 | 三菱化学株式会社 | チアジアゾ−ル誘導体及びこれを有効成分とする殺虫殺ダニ剤 |
| GB8807275D0 (en) * | 1988-03-26 | 1988-04-27 | Synphar Lab Inc | Chemical compounds |
| JPH01249768A (ja) * | 1988-03-30 | 1989-10-05 | Nippon Tokushu Noyaku Seizo Kk | Ｎ−置換フエニル−ヘテロ環式化合物及び除草剤 |
| DE3914337A1 (de) * | 1989-04-29 | 1990-10-31 | Basf Ag | 3(2h)-pyridazinonderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen |
| NZ233503A (en) * | 1989-05-15 | 1991-06-25 | Janssen Pharmaceutica Nv | Substituted (thio)morpholinyl and piperazinyl alkylphenol ethers |
| NZ234760A (en) * | 1989-08-18 | 1991-09-25 | Sterling Drug Inc | Antiviral oxazole compounds and compositions |
| US4942241A (en) * | 1989-08-21 | 1990-07-17 | Sterling Drug Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
| US5552420A (en) * | 1994-05-13 | 1996-09-03 | Sterling Winthrop Inc. | Therapeutic phenoxyalkylazoles and phenoxyalkylazines |
| AU2547895A (en) * | 1994-05-13 | 1995-12-05 | Sanofi Winthrop, Inc. | Therapeutic phenoxyalkylheterocycles |
| US5514679A (en) * | 1994-05-13 | 1996-05-07 | Sterling Winthrop Inc. | Therapeutic phenoxyalklpyridazines and intermediates therefor |
-
1994
- 1994-05-13 US US08/242,529 patent/US5453433A/en not_active Expired - Lifetime
-
1995
- 1995-05-10 AU AU25458/95A patent/AU691923B2/en not_active Expired
- 1995-05-10 WO PCT/US1995/005790 patent/WO1995031198A1/en not_active Ceased
- 1995-05-10 DE DE69531491T patent/DE69531491D1/de not_active Expired - Lifetime
- 1995-05-10 CN CN95193048A patent/CN1095664C/zh not_active Expired - Lifetime
- 1995-05-10 EP EP95919773A patent/EP0759755B1/en not_active Expired - Lifetime
- 1995-05-10 CZ CZ19963332A patent/CZ289061B6/cs not_active IP Right Cessation
- 1995-05-10 JP JP52972095A patent/JP4158946B2/ja not_active Expired - Lifetime
- 1995-05-10 RU RU96123713A patent/RU2140916C1/ru active
- 1995-05-10 KR KR1019960706400A patent/KR100383495B1/ko not_active Expired - Lifetime
- 1995-05-10 PL PL95317259A patent/PL181099B1/pl unknown
- 1995-05-10 AT AT95919773T patent/ATE247112T1/de not_active IP Right Cessation
- 1995-05-10 CA CA002190130A patent/CA2190130C/en not_active Expired - Lifetime
- 1995-05-10 NZ NZ285910A patent/NZ285910A/en not_active IP Right Cessation
- 1995-06-07 US US08/477,040 patent/US5567719A/en not_active Expired - Lifetime
-
1996
- 1996-08-30 US US08/706,108 patent/US5650419A/en not_active Expired - Lifetime
- 1996-11-11 NO NO964773A patent/NO307256B1/no not_active IP Right Cessation
-
1997
- 1997-05-27 US US08/863,388 patent/US5750527A/en not_active Expired - Lifetime
-
1998
- 1998-03-31 US US09/052,178 patent/US5821257A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69531491D1 (de) | 2003-09-18 |
| EP0759755A4 (en) | 1997-05-07 |
| CZ333296A3 (en) | 1997-08-13 |
| AU2545895A (en) | 1995-12-05 |
| EP0759755B1 (en) | 2003-08-13 |
| ATE247112T1 (de) | 2003-08-15 |
| AU691923B2 (en) | 1998-05-28 |
| CZ289061B6 (cs) | 2001-10-17 |
| KR100383495B1 (ko) | 2004-05-20 |
| KR970702722A (ko) | 1997-06-10 |
| CN1148339A (zh) | 1997-04-23 |
| US5750527A (en) | 1998-05-12 |
| MX9605513A (es) | 1998-05-31 |
| NO964773L (no) | 1996-11-11 |
| RU2140916C1 (ru) | 1999-11-10 |
| CN1095664C (zh) | 2002-12-11 |
| NO964773D0 (no) | 1996-11-11 |
| EP0759755A1 (en) | 1997-03-05 |
| PL181099B1 (pl) | 2001-05-31 |
| US5821257A (en) | 1998-10-13 |
| CA2190130C (en) | 2003-06-10 |
| JP4158946B2 (ja) | 2008-10-01 |
| US5567719A (en) | 1996-10-22 |
| US5650419A (en) | 1997-07-22 |
| PL317259A1 (en) | 1997-04-01 |
| US5453433A (en) | 1995-09-26 |
| WO1995031198A1 (en) | 1995-11-23 |
| JPH10500136A (ja) | 1998-01-06 |
| NZ285910A (en) | 1997-11-24 |
| CA2190130A1 (en) | 1995-11-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |