NO307255B1 - Nye forbindelser og antitumormidler - Google Patents

Nye forbindelser og antitumormidler

Info

Publication number
NO307255B1
NO307255B1 NO965305A NO965305A NO307255B1 NO 307255 B1 NO307255 B1 NO 307255B1 NO 965305 A NO965305 A NO 965305A NO 965305 A NO965305 A NO 965305A NO 307255 B1 NO307255 B1 NO 307255B1
Authority
NO
Norway
Prior art keywords
hydrogen atom
group
lower alkyl
alkyl group
new compounds
Prior art date
Application number
NO965305A
Other languages
English (en)
Norwegian (no)
Other versions
NO965305L (no
NO965305D0 (no
Inventor
Kyoji Tomita
Katsumi Chiba
Shigeki Kashimoto
Koh-Ichiro Shibamori
Yasunori Tsuzuki
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of NO965305D0 publication Critical patent/NO965305D0/no
Publication of NO965305L publication Critical patent/NO965305L/no
Publication of NO307255B1 publication Critical patent/NO307255B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO965305A 1994-06-14 1996-12-11 Nye forbindelser og antitumormidler NO307255B1 (no)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP15657894 1994-06-14
JP19792194 1994-07-28
JP30691494 1994-11-15
JP33995694 1994-12-28
JP8170595 1995-03-13
PCT/JP1995/001110 WO1995034559A1 (en) 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent

Publications (3)

Publication Number Publication Date
NO965305D0 NO965305D0 (no) 1996-12-11
NO965305L NO965305L (no) 1997-02-04
NO307255B1 true NO307255B1 (no) 2000-03-06

Family

ID=27524935

Family Applications (1)

Application Number Title Priority Date Filing Date
NO965305A NO307255B1 (no) 1994-06-14 1996-12-11 Nye forbindelser og antitumormidler

Country Status (27)

Country Link
US (1) US5817669A (oth)
EP (1) EP0787726B1 (oth)
JP (1) JP3391796B2 (oth)
KR (1) KR100350921B1 (oth)
CN (1) CN1053668C (oth)
AT (1) ATE209645T1 (oth)
AU (1) AU679859B2 (oth)
BR (1) BR9508037A (oth)
CA (1) CA2192824C (oth)
CZ (1) CZ292631B6 (oth)
DE (1) DE69524251T2 (oth)
DK (1) DK0787726T3 (oth)
ES (1) ES2163512T3 (oth)
FI (1) FI112485B (oth)
HK (1) HK1000495A1 (oth)
HU (1) HU220072B (oth)
MX (1) MX9606331A (oth)
NO (1) NO307255B1 (oth)
NZ (1) NZ287139A (oth)
PL (1) PL181867B1 (oth)
PT (1) PT787726E (oth)
RO (1) RO117793B1 (oth)
RU (1) RU2151770C1 (oth)
SI (1) SI0787726T1 (oth)
SK (1) SK281341B6 (oth)
TW (1) TW319769B (oth)
WO (1) WO1995034559A1 (oth)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20040309A2 (en) 2001-09-26 2006-05-31 Bayer Pharmaceuticals Corporation 1,6-nafthyridine derivatives as antidiabetics
US6802423B2 (en) * 2002-02-20 2004-10-12 Trans Global Foods, Inc. Disposable food delivery apparatus
WO2004091627A2 (en) * 2003-04-07 2004-10-28 Cylene Pharmaceuticals, Inc. Heterocyclic substituted 1,4-dihydro-4-oxo-1,8-naphthpyridine analogs
PT1666477E (pt) * 2003-09-10 2013-08-28 Kyorin Seiyaku Kk Derivado de 7-(4-substituído-3-ciclopropilaminometil-1- pirrolidinil) quinolonecarboxílico
DE10352979A1 (de) * 2003-11-13 2005-06-09 Merck Patent Gmbh Pyridopyrimidinone
AU2013201203C1 (en) * 2004-03-15 2015-04-23 Sumitomo Dainippon Pharma Co., Ltd. Sns-595 and methods of using the same
ES2334802T3 (es) * 2004-03-15 2010-03-16 Sunesis Pharmaceuticals, Inc. Sns-595 y metodos de uso del mismo.
EP1805174A1 (en) * 2004-10-14 2007-07-11 F.Hoffmann-La Roche Ag 1,5-naphthyridine azolidinones having cdk1 antiproliferative activity
RU2405782C2 (ru) * 2004-10-14 2010-12-10 Ф.Хоффманн-Ля Рош Аг Хиназолинилметилентиазолиноны в качестве cdk-1 ингибиторов
RU2420524C2 (ru) * 2005-05-19 2011-06-10 Дайити Санкио Компани, Лимитед Производные три- или тетра-замещенного-3-аминопирролидина
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
EP1926372A2 (en) * 2005-08-19 2008-06-04 Cylene Pharmaceuticals, Inc. HUMAN RIBOSOMAL DNA(rDNA) AND RIBOSOMAL RNA (rRNA) NUCLEIC ACIDS AND USES THEREOF
US8580814B2 (en) * 2006-04-03 2013-11-12 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
AU2013219242C1 (en) * 2005-09-02 2016-09-22 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
RU2428983C2 (ru) * 2005-09-02 2011-09-20 Санесис Фармасьютикалз, Инк. Способы применения (+)-1,4-дигидро-7-[(3s,4s)-3-метокси-4-(метиламино)-1-пирролидинил]-4-оксо-1-(2-тиазолил)-1,8-нафтиридин-3-карбоновой кислоты для лечения рака
CN104873502A (zh) * 2005-09-02 2015-09-02 逊尼希思制药公司 使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸治疗癌症的方法
KR20170118936A (ko) * 2005-09-02 2017-10-25 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한 (＋)-1,4-디히드로-7-［(3ｓ,4ｓ)-3-메톡시-4-(메틸아미노)-1-피롤리디닐］-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
KR20080041298A (ko) * 2005-09-02 2008-05-09 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한(＋)-1,4-디히드로-7-[(3ｓ,4ｓ)-3-메톡시-4-(메틸아미노)-1-피롤리디닐]-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
US7642270B2 (en) 2005-09-14 2010-01-05 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
CA2622725A1 (en) * 2005-09-14 2007-03-22 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase
TW200800983A (en) 2005-09-14 2008-01-01 Janssen Pharmaceutica Nv 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase
CN104027333B (zh) 2006-06-12 2017-05-17 逊尼希思制药公司 治疗癌症的化合物和组合物
US20100048609A1 (en) * 2006-08-01 2010-02-25 Jacobs Jeffrey W Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
EP3025712A1 (en) 2006-08-02 2016-06-01 Sunesis Pharmaceuticals, Inc. Combined use of (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid and cytarabine (ara-c) for the treatment of leukemia
EP3141250A1 (en) * 2007-10-22 2017-03-15 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid in combination therapy
CA2708264C (en) * 2007-12-10 2018-07-03 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
RU2015106671A (ru) 2008-12-31 2015-06-27 Санесис Фармасьютикалз, Инк. Способ получения (+)-1,4-дигидро-7-[(3s,4s)-3-метокси-4-(метиламино)-1-пирролидинил]-4-оксо-1-(2-тиазолил)-1,8-нафтиридин-3-карбоновой кислоты
SG173855A1 (en) 2009-02-27 2011-09-29 Sunesis Pharmaceuticals Inc Methods of using sns-595 for treatment of cancer subjects with reduced brca2 activity
UA110465C2 (en) 2009-09-04 2016-01-12 Sunesis Pharmaceutecals Inc Stable sns-595 composition
WO2011056566A2 (en) * 2009-10-26 2011-05-12 Sunesis Pharmaceuticals, Inc. Compounds and methods for treatment of cancer
RS55582B1 (sr) * 2011-05-13 2017-06-30 Array Biopharma Inc Jedinjenja pirolidinil uree, pirolidinil tiouree i pirolidinil guanidina kao inhibitori trka kinaze
CN103497186B (zh) * 2013-09-24 2015-02-25 浙江司太立制药股份有限公司 含有烷氧亚氨基取代的萘啶酮羧酸衍生物及其制备方法
WO2018174266A1 (ja) * 2017-03-24 2018-09-27 湧永製薬株式会社 新規ピリドンカルボン酸誘導体又はその塩

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988463A (en) * 1974-05-06 1976-10-26 Merck & Co., Inc. Method of preventing metastasis of H. Ep. No. 3
US4384001A (en) * 1978-12-21 1983-05-17 Gosalvez Mario Treatment of tumors with thiazolidine-4-carboxylic acid
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
DE3577089D1 (de) * 1984-01-26 1990-05-17 Abbott Lab Antibakterielle chinolinderivate.
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
JPS61152682A (ja) * 1984-12-27 1986-07-11 Dainippon Pharmaceut Co Ltd ピリドンカルボン酸誘導体、そのエステルおよびその塩
JPS61251667A (ja) * 1985-04-30 1986-11-08 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環化合物
GR861530B (en) * 1985-06-13 1986-12-31 Schering Corp Preparation process for polycyclic quinoline of naphthyridine and pyrazinopyridine
US4851425A (en) * 1985-06-14 1989-07-25 The Upjohn Company Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents
JPS6233176A (ja) * 1985-08-05 1987-02-13 Toyama Chem Co Ltd １，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩
JP2704428B2 (ja) * 1988-06-15 1998-01-26 富山化学工業株式会社 キノロンカルボン酸誘導体またはその塩
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
JPH06233176A (ja) * 1993-01-29 1994-08-19 Sony Corp ビデオカメラ

Also Published As

Publication number Publication date
AU679859B2 (en) 1997-07-10
MX9606331A (es) 1997-03-29
FI965020A0 (fi) 1996-12-13
HU9603455D0 (en) 1997-02-28
EP0787726B1 (en) 2001-11-28
DE69524251D1 (de) 2002-01-10
CZ292631B6 (cs) 2003-11-12
FI965020A7 (fi) 1996-12-16
RU2151770C1 (ru) 2000-06-27
SI0787726T1 (en) 2002-04-30
CN1053668C (zh) 2000-06-21
US5817669A (en) 1998-10-06
RO117793B1 (ro) 2002-07-30
WO1995034559A1 (en) 1995-12-21
JP3391796B2 (ja) 2003-03-31
DK0787726T3 (da) 2002-02-11
KR100350921B1 (ko) 2002-11-18
EP0787726A4 (oth) 1997-08-06
HU220072B (hu) 2001-10-28
CZ364396A3 (en) 1997-06-11
SK281341B6 (sk) 2001-02-12
DE69524251T2 (de) 2002-07-11
NO965305L (no) 1997-02-04
ATE209645T1 (de) 2001-12-15
ES2163512T3 (es) 2002-02-01
NZ287139A (en) 1997-07-27
BR9508037A (pt) 1997-09-16
FI112485B (fi) 2003-12-15
CA2192824A1 (en) 1995-12-21
HUT75777A (en) 1997-05-28
CN1158614A (zh) 1997-09-03
NO965305D0 (no) 1996-12-11
PL317726A1 (en) 1997-04-28
EP0787726A1 (en) 1997-08-06
PT787726E (pt) 2002-04-29
SK157496A3 (en) 1997-08-06
AU2576795A (en) 1996-01-05
PL181867B1 (pl) 2001-09-28
TW319769B (oth) 1997-11-11
CA2192824C (en) 2006-11-07
HK1000495A1 (en) 2002-07-19

Similar Documents

Publication Publication Date Title
NO307255B1 (no) Nye forbindelser og antitumormidler
NO992549D0 (no) Sukkerforbindelse, geleringsmiddel og fremgangsmÕte for fremstilling derav
EP0256503A3 (en) Pyridinecarboxamide derivatives and their use as fungicide
DK0474243T3 (da) 1-methylcarbapenemderivater og fremgangsmåde til fremstilling deraf
HUT59378A (en) Process for producing urea derivatives and pharmaceutical compositions comprising such compounds
NO912462D0 (no) Fremstilling og anvendelse av bisfosfonsyrederivater.
NZ221699A (en) Pyridazinone derivatives; pharmaceutical compositions and intermediates
YU165791A (sh) Postupak za pripremanje derivata 8-hlorohinolona
DK0812838T3 (da) Pyridoncarboxylsyrederivater substitueret med bicyclisk aminogruppe, estere og salte deraf og bicyclisk amin som mellemprodukt
DE3667788D1 (de) Diphenyletherherbizide.
ATE122683T1 (de) Epoxybernsteinsäurederivate, verwendbar als spezifische hemmer von cathepsin b.
DE69828087D1 (de) Aminderivate
MY104164A (en) Heterocyclic compounds.

Legal Events

Date Code Title Description
MK1K Patent expired