NO306194B1 - Tolags fosfolipidvesikkel, fremgangsmåte til fremstilling og anvendelse derav, samt farmasöytisk preparat som omfatter vesikkelen - Google Patents

Tolags fosfolipidvesikkel, fremgangsmåte til fremstilling og anvendelse derav, samt farmasöytisk preparat som omfatter vesikkelen Download PDF

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Publication number
NO306194B1
NO306194B1 NO923703A NO923703A NO306194B1 NO 306194 B1 NO306194 B1 NO 306194B1 NO 923703 A NO923703 A NO 923703A NO 923703 A NO923703 A NO 923703A NO 306194 B1 NO306194 B1 NO 306194B1
Authority
NO
Norway
Prior art keywords
membrane
accordance
weight
phospholipid
vesicles
Prior art date
Application number
NO923703A
Other languages
English (en)
Norwegian (no)
Other versions
NO923703L (no
NO923703D0 (no
Inventor
Reinhard Glueck
Peter Klein
Peter Hermann
Original Assignee
Nika Health Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nika Health Products Ltd filed Critical Nika Health Products Ltd
Publication of NO923703D0 publication Critical patent/NO923703D0/no
Publication of NO923703L publication Critical patent/NO923703L/no
Publication of NO306194B1 publication Critical patent/NO306194B1/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6839Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting material from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • A61K47/6913Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome the liposome being modified on its surface by an antibody
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Feedback Control In General (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Fittings On The Vehicle Exterior For Carrying Loads, And Devices For Holding Or Mounting Articles (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Air Conditioning Control Device (AREA)
NO923703A 1991-02-02 1992-09-24 Tolags fosfolipidvesikkel, fremgangsmåte til fremstilling og anvendelse derav, samt farmasöytisk preparat som omfatter vesikkelen NO306194B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP91101414A EP0497997B1 (en) 1991-02-02 1991-02-02 Synthetic membrane vesicles containing functionally active fusion peptides as drug delivery systems
PCT/EP1992/000089 WO1992013525A1 (en) 1991-02-02 1992-01-17 Synthetic membrane vesicles containing functionally active fusion peptides as drug delivery systems

Publications (3)

Publication Number Publication Date
NO923703D0 NO923703D0 (no) 1992-09-24
NO923703L NO923703L (no) 1992-11-26
NO306194B1 true NO306194B1 (no) 1999-10-04

Family

ID=8206362

Family Applications (1)

Application Number Title Priority Date Filing Date
NO923703A NO306194B1 (no) 1991-02-02 1992-09-24 Tolags fosfolipidvesikkel, fremgangsmåte til fremstilling og anvendelse derav, samt farmasöytisk preparat som omfatter vesikkelen

Country Status (22)

Country Link
US (1) US6040167A (fi)
EP (1) EP0497997B1 (fi)
JP (1) JP3404037B2 (fi)
KR (1) KR100205693B1 (fi)
AT (1) ATE125154T1 (fi)
AU (1) AU657730B2 (fi)
BG (1) BG61215B1 (fi)
BR (1) BR9204116A (fi)
CA (1) CA2079685C (fi)
DE (1) DE69111414T2 (fi)
DK (1) DK0497997T3 (fi)
ES (1) ES2077086T3 (fi)
FI (1) FI109969B (fi)
GE (1) GEP20002229B (fi)
GR (1) GR3017490T3 (fi)
HK (1) HK56696A (fi)
HU (1) HU215533B (fi)
NO (1) NO306194B1 (fi)
PL (2) PL296382A1 (fi)
RO (1) RO114736B1 (fi)
RU (1) RU2125868C1 (fi)
WO (1) WO1992013525A1 (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69116144T2 (de) * 1991-02-14 1996-05-09 Baxter Int Bindung substratspezifischer affinitätssubstanzen an liposomen
US5603872A (en) * 1991-02-14 1997-02-18 Baxter International Inc. Method of binding recognizing substances to liposomes
US5879656A (en) * 1993-10-26 1999-03-09 Thomas Jefferson University Methods of treating metastatic colorectal cancer with ST receptor binding compounds
US7097839B1 (en) 1993-10-26 2006-08-29 Thomas Jefferson University ST receptor binding compounds and methods of using the same
EP0762870B1 (en) * 1994-05-31 2002-09-11 INEX Pharmaceutical Corp. Virosome-mediated intracellular delivery of therapeutic agents
US6861053B1 (en) * 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US5908777A (en) * 1995-06-23 1999-06-01 University Of Pittsburgh Lipidic vector for nucleic acid delivery
WO1997004748A2 (en) * 1995-08-01 1997-02-13 Advanced Therapies, Inc. Enhanced artificial viral envelopes for cellular delivery of therapeutic substances
HUP9901790A3 (en) * 1996-05-08 2010-11-29 Nika Health Products Ltd Cationic virosomes as transfer system for genetic material
US7148324B1 (en) 1998-12-14 2006-12-12 Dendreon Corporation Compositions and methods for enhancement of major histocompatibility complex class I restricted antigen presentation
NZ512807A (en) * 1998-12-14 2003-10-31 Dendreon Corp Compositions and methods for enhancement of major histocompatibility complex class 1 restricted antigen presentation by attaching the antigen to a specific peptide
AU762006B2 (en) 1998-12-24 2003-06-19 Ucb Peptidic product, process and composition
SK4782002A3 (en) * 1999-10-08 2002-09-10 Nika Health Products Ltd Lipidic vesicles, a method for the manufacture thereof pharmaceutical composition containing the same and use thereof
WO2001044023A1 (de) * 1999-12-17 2001-06-21 Duerschinger Guenter Induktiv aktivierbare zündkapsel für insassen-rückhaltesysteme und prüfschaltung für diese zündkapsel
US20040028687A1 (en) * 2002-01-15 2004-02-12 Waelti Ernst Rudolf Methods and compositions for the targeted delivery of therapeutic substances to specific cells and tissues
US20040176283A1 (en) * 2002-04-01 2004-09-09 Robinson John A. Methods and compositions for the design of synthetic vaccines
ATE476963T1 (de) * 2002-04-29 2010-08-15 Biotesys Gmbh Polymerisierte peptid-modifizierte lipide als biologische transportsysteme für mikronutrients
EP1447080A1 (en) * 2003-02-13 2004-08-18 Bestewil Holding B.V. Method for producing virosome-like particles
US8658203B2 (en) 2004-05-03 2014-02-25 Merrimack Pharmaceuticals, Inc. Liposomes useful for drug delivery to the brain
ES2967961T3 (es) 2004-05-03 2024-05-06 Ipsen Biopharm Ltd Liposomas útiles en la administración de fármacos
US20070160658A1 (en) * 2005-10-20 2007-07-12 The Penn State Research Foundation Delivery system for diagnostic and therapeutic agents
EP2839837B1 (en) * 2006-09-15 2019-05-08 Children's Hospital of Eastern Ontario Research Institute Inc. Oncolytic farmington rhabdovirus
BR122021024957B1 (pt) 2015-10-16 2023-12-12 Ipsen Biopharm Ltd Processos de produção de uma composição de irinotecano lipossômico estabilizado em armazenamento

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0047480B1 (en) * 1980-09-05 1986-02-05 Institut Armand Frappier Formation of an immunosome exclusively made of viral antigens reconstituted on an artificial membrane
US4871488A (en) * 1985-04-22 1989-10-03 Albany Medical College Of Union University Reconstituting viral glycoproteins into large phospholipid vesicles
US4663161A (en) * 1985-04-22 1987-05-05 Mannino Raphael J Liposome methods and compositions
US4790987A (en) * 1985-11-15 1988-12-13 Research Corporation Viral glycoprotein subunit vaccine
US5000960A (en) * 1987-03-13 1991-03-19 Micro-Pak, Inc. Protein coupling to lipid vesicles
IL86650A0 (en) * 1987-06-30 1988-11-30 Biophor Corp Animal derived cells and liposomes,having an antigenic protein incorporated into their membrane
WO1991003258A1 (en) * 1989-09-01 1991-03-21 Board Of Regents, The University Of Texas System Immunoliposomes for transmittal of activating signals to cells
AU652778B2 (en) * 1990-10-15 1994-09-08 Quest International B.V. Treatment composition

Also Published As

Publication number Publication date
BG61215B1 (en) 1997-03-31
NO923703L (no) 1992-11-26
RU2125868C1 (ru) 1999-02-10
HU215533B (hu) 1999-01-28
NO923703D0 (no) 1992-09-24
WO1992013525A1 (en) 1992-08-20
DE69111414T2 (de) 1996-02-01
DK0497997T3 (da) 1995-11-27
HUT66194A (en) 1994-10-28
PL296382A1 (en) 1993-11-02
EP0497997A1 (en) 1992-08-12
AU657730B2 (en) 1995-03-23
KR100205693B1 (en) 1999-07-01
FI109969B (fi) 2002-11-15
ES2077086T3 (es) 1995-11-16
GR3017490T3 (en) 1995-12-31
CA2079685A1 (en) 1992-08-03
FI924418A (fi) 1993-04-03
BR9204116A (pt) 1993-06-08
HK56696A (en) 1996-04-12
FI924418A0 (fi) 1992-10-01
HU9203141D0 (en) 1992-12-28
ATE125154T1 (de) 1995-08-15
RO114736B1 (ro) 1999-07-30
JP3404037B2 (ja) 2003-05-06
GEP20002229B (en) 2000-09-25
PL170169B1 (en) 1996-10-31
US6040167A (en) 2000-03-21
CA2079685C (en) 2001-11-27
JPH05505406A (ja) 1993-08-12
DE69111414D1 (de) 1995-08-24
BG96928A (bg) 1994-03-24
EP0497997B1 (en) 1995-07-19
AU1169392A (en) 1992-09-07

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