NO306113B1 - Adhesjonsreseptorantagonister, farmasöytiske preparater som inneholder slike forbindelser, samt anvendelse av forbindelsene til fremstilling av legemidler - Google Patents
Adhesjonsreseptorantagonister, farmasöytiske preparater som inneholder slike forbindelser, samt anvendelse av forbindelsene til fremstilling av legemidlerInfo
- Publication number
- NO306113B1 NO306113B1 NO954458A NO954458A NO306113B1 NO 306113 B1 NO306113 B1 NO 306113B1 NO 954458 A NO954458 A NO 954458A NO 954458 A NO954458 A NO 954458A NO 306113 B1 NO306113 B1 NO 306113B1
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- drugs
- manufacture
- receptor antagonists
- pharmaceutical preparations
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 102000019997 adhesion receptor Human genes 0.000 title 1
- 108010013985 adhesion receptor Proteins 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4439846A DE4439846A1 (de) | 1994-11-08 | 1994-11-08 | Adhäsionsrezeptor-Antagonisten |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO954458D0 NO954458D0 (no) | 1995-11-07 |
| NO954458L NO954458L (no) | 1996-05-09 |
| NO306113B1 true NO306113B1 (no) | 1999-09-20 |
Family
ID=6532768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO954458A NO306113B1 (no) | 1994-11-08 | 1995-11-07 | Adhesjonsreseptorantagonister, farmasöytiske preparater som inneholder slike forbindelser, samt anvendelse av forbindelsene til fremstilling av legemidler |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5776937A (ru) |
| EP (1) | EP0711770A1 (ru) |
| JP (1) | JPH08208629A (ru) |
| KR (1) | KR100384978B1 (ru) |
| CN (1) | CN1069640C (ru) |
| AR (1) | AR002245A1 (ru) |
| AU (1) | AU704184B2 (ru) |
| BR (1) | BR9505109A (ru) |
| CA (1) | CA2162223A1 (ru) |
| CO (1) | CO4520229A1 (ru) |
| CZ (1) | CZ291049B6 (ru) |
| DE (1) | DE4439846A1 (ru) |
| FI (1) | FI955351A (ru) |
| HU (1) | HU217085B (ru) |
| NO (1) | NO306113B1 (ru) |
| PL (1) | PL183595B1 (ru) |
| RU (1) | RU2155762C2 (ru) |
| SK (1) | SK281815B6 (ru) |
| TR (1) | TR199501389A2 (ru) |
| TW (1) | TW316903B (ru) |
| UA (1) | UA41928C2 (ru) |
| ZA (1) | ZA959434B (ru) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0710657T3 (da) * | 1994-11-02 | 1999-05-25 | Merck Patent Gmbh | Adhæsionsreceptor-antagonister |
| US6046331A (en) * | 1998-12-17 | 2000-04-04 | Synaptic Pharmaceutical Corporation | Imidazolones and their use in treating benign prostatic hyperplasia and other disorders |
| AU2713500A (en) | 1998-12-23 | 2000-07-31 | G.D. Searle & Co. | Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| JP2002535680A (ja) | 1999-01-27 | 2002-10-22 | ファルマシア・アンド・アップジョン・カンパニー | 延長因子ｐ活性モジュレーターのアッセイ方法 |
| AU2003275480A1 (en) * | 2002-10-07 | 2004-05-04 | Smithkline Beecham Corporation | Compounds |
| CN102796091A (zh) * | 2011-05-24 | 2012-11-28 | 北大方正集团有限公司 | 取代的噁唑烷酮化合物及其制备方法和应用 |
| IN2015DN00961A (ru) * | 2012-10-29 | 2015-06-12 | Hoffmann La Roche | |
| CN104230915B (zh) * | 2014-08-29 | 2016-08-17 | 南京大学 | 含噻唑烷二酮的苯基哌嗪衍生物及其制备方法与用途 |
| JP2020527133A (ja) | 2017-06-20 | 2020-09-03 | インブリア ファーマシューティカルズ， インコーポレイテッド | 心臓代謝の効率を高めるための組成物および方法 |
| US11530184B2 (en) | 2020-06-30 | 2022-12-20 | Imbria Pharmaceuticals, Inc. | Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11780811B2 (en) | 2020-06-30 | 2023-10-10 | Imbria Pharmaceuticals, Inc. | Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11883396B2 (en) | 2021-05-03 | 2024-01-30 | Imbria Pharmaceuticals, Inc. | Methods of treating kidney conditions using modified forms of trimetazidine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3723797A1 (de) * | 1987-07-18 | 1989-01-26 | Merck Patent Gmbh | Oxazolidinone |
| US5053393A (en) * | 1988-07-20 | 1991-10-01 | Monsanto Company | Novel platelet-aggregation inhibitor |
| US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
| DE4005371A1 (de) * | 1990-02-21 | 1991-08-22 | Merck Patent Gmbh | Oxazolidinone |
| DE4017211A1 (de) * | 1990-05-29 | 1991-12-05 | Merck Patent Gmbh | Oxazolidinone |
| DE4405633A1 (de) * | 1993-05-01 | 1994-11-03 | Merck Patent Gmbh | Adhäsionsrezeptor-Antagonisten |
| DE4332384A1 (de) * | 1993-09-23 | 1995-03-30 | Merck Patent Gmbh | Adhäsionsrezeptor-Antagonisten III |
-
1994
- 1994-11-08 DE DE4439846A patent/DE4439846A1/de not_active Withdrawn
-
1995
- 1995-10-26 EP EP95116889A patent/EP0711770A1/de not_active Withdrawn
- 1995-11-01 UA UA95114761A patent/UA41928C2/ru unknown
- 1995-11-02 SK SK1368-95A patent/SK281815B6/sk unknown
- 1995-11-02 AU AU36618/95A patent/AU704184B2/en not_active Ceased
- 1995-11-06 TW TW084111748A patent/TW316903B/zh active
- 1995-11-06 CZ CZ19952888A patent/CZ291049B6/cs not_active IP Right Cessation
- 1995-11-06 CA CA002162223A patent/CA2162223A1/en not_active Abandoned
- 1995-11-07 BR BR9505109A patent/BR9505109A/pt not_active IP Right Cessation
- 1995-11-07 FI FI955351A patent/FI955351A/fi not_active IP Right Cessation
- 1995-11-07 HU HU9503191A patent/HU217085B/hu not_active IP Right Cessation
- 1995-11-07 CN CN95118753A patent/CN1069640C/zh not_active Expired - Fee Related
- 1995-11-07 NO NO954458A patent/NO306113B1/no not_active IP Right Cessation
- 1995-11-07 US US08/551,743 patent/US5776937A/en not_active Expired - Fee Related
- 1995-11-07 ZA ZA959434A patent/ZA959434B/xx unknown
- 1995-11-07 KR KR1019950040017A patent/KR100384978B1/ko not_active IP Right Cessation
- 1995-11-07 PL PL95311257A patent/PL183595B1/pl not_active IP Right Cessation
- 1995-11-08 AR ARP950100091A patent/AR002245A1/es unknown
- 1995-11-08 RU RU95119427/04A patent/RU2155762C2/ru not_active IP Right Cessation
- 1995-11-08 CO CO95052761A patent/CO4520229A1/es unknown
- 1995-11-08 JP JP7313684A patent/JPH08208629A/ja active Pending
- 1995-11-08 TR TR95/01389A patent/TR199501389A2/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ288895A3 (en) | 1996-06-12 |
| CA2162223A1 (en) | 1996-05-09 |
| NO954458D0 (no) | 1995-11-07 |
| TW316903B (ru) | 1997-10-01 |
| KR960017663A (ko) | 1996-06-17 |
| CZ291049B6 (cs) | 2002-12-11 |
| AU704184B2 (en) | 1999-04-15 |
| KR100384978B1 (ko) | 2003-09-02 |
| FI955351A (fi) | 1996-05-09 |
| RU2155762C2 (ru) | 2000-09-10 |
| UA41928C2 (ru) | 2001-10-15 |
| HUT76052A (en) | 1997-06-30 |
| SK281815B6 (sk) | 2001-08-06 |
| EP0711770A1 (de) | 1996-05-15 |
| DE4439846A1 (de) | 1996-05-09 |
| AU3661895A (en) | 1996-05-23 |
| ZA959434B (en) | 1996-05-15 |
| PL311257A1 (en) | 1996-05-13 |
| PL183595B1 (pl) | 2002-06-28 |
| JPH08208629A (ja) | 1996-08-13 |
| CN1069640C (zh) | 2001-08-15 |
| TR199501389A2 (tr) | 1996-07-21 |
| CO4520229A1 (es) | 1997-10-15 |
| US5776937A (en) | 1998-07-07 |
| HU217085B (hu) | 1999-11-29 |
| NO954458L (no) | 1996-05-09 |
| FI955351A0 (fi) | 1995-11-07 |
| AR002245A1 (es) | 1998-03-11 |
| BR9505109A (pt) | 1997-09-09 |
| SK136895A3 (en) | 1996-06-05 |
| CN1132201A (zh) | 1996-10-02 |
| HU9503191D0 (en) | 1996-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |