NO304373B1 - Imidazol-derivater, farmas°ytiske preparater inneholdende dem og anvendelse av dem - Google Patents

Imidazol-derivater, farmas°ytiske preparater inneholdende dem og anvendelse av dem

Info

Publication number
NO304373B1
NO304373B1 NO942374A NO942374A NO304373B1 NO 304373 B1 NO304373 B1 NO 304373B1 NO 942374 A NO942374 A NO 942374A NO 942374 A NO942374 A NO 942374A NO 304373 B1 NO304373 B1 NO 304373B1
Authority
NO
Norway
Prior art keywords
alkyl
phenyl
pct
alkoxy
alkoxycarbonyl
Prior art date
Application number
NO942374A
Other languages
English (en)
Norwegian (no)
Other versions
NO942374L (no
NO942374D0 (ru
Inventor
Lawrence Stephen Clegg
Ian Michael Hunneyball
Colin Gerhart Pryce Jones
Paul Rafferty
Leslie Steele
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of NO942374L publication Critical patent/NO942374L/no
Publication of NO942374D0 publication Critical patent/NO942374D0/no
Publication of NO304373B1 publication Critical patent/NO304373B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Lubricants (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
NO942374A 1991-12-23 1994-06-22 Imidazol-derivater, farmas°ytiske preparater inneholdende dem og anvendelse av dem NO304373B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919127304A GB9127304D0 (en) 1991-12-23 1991-12-23 Therapeutic agents
PCT/EP1992/002899 WO1993013075A1 (en) 1991-12-23 1992-12-12 1-(arylalkyl-aminoalkyl)imidazole derivatives, processes of preparation and use as therapeutical agents
CN93107988A CN1037511C (zh) 1991-12-23 1993-06-22 1－(芳烷基－氨烷基)咪唑化合物的制备方法

Publications (3)

Publication Number Publication Date
NO942374L NO942374L (no) 1994-06-22
NO942374D0 NO942374D0 (ru) 1994-06-22
NO304373B1 true NO304373B1 (no) 1998-12-07

Family

ID=36822309

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942374A NO304373B1 (no) 1991-12-23 1994-06-22 Imidazol-derivater, farmas°ytiske preparater inneholdende dem og anvendelse av dem

Country Status (29)

Country Link
US (1) US5547972A (ru)
EP (1) EP0618907B1 (ru)
JP (1) JP2633087B2 (ru)
CN (1) CN1037511C (ru)
AT (1) ATE179416T1 (ru)
AU (1) AU656839B2 (ru)
BG (1) BG98812A (ru)
CA (1) CA2126177A1 (ru)
CZ (1) CZ153394A3 (ru)
DE (1) DE69229057T2 (ru)
ES (1) ES2131574T3 (ru)
FI (1) FI943020A (ru)
GB (1) GB9127304D0 (ru)
HR (1) HRP921457A2 (ru)
HU (2) HUT67372A (ru)
IL (1) IL104168A (ru)
IN (1) IN174436B (ru)
MX (1) MX9207491A (ru)
NO (1) NO304373B1 (ru)
NZ (1) NZ246336A (ru)
PH (1) PH30660A (ru)
PL (1) PL172497B1 (ru)
RO (1) RO113985B1 (ru)
RU (1) RU2118957C1 (ru)
SI (1) SI9200411A (ru)
SK (1) SK75294A3 (ru)
WO (1) WO1993013075A1 (ru)
YU (1) YU48294B (ru)
ZA (1) ZA929914B (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9312893D0 (en) * 1993-06-22 1993-08-04 Boots Co Plc Therapeutic agents
US5741800A (en) * 1993-06-22 1998-04-21 Knoll Aktiengesellachaft Azolyl-cyclic amine derivates with immunomodulatory activity
AU1891295A (en) * 1994-02-22 1995-09-04 Knoll Aktiengesellschaft Use of 1-(arylalkylaminoalkyl) imidazoles for treating neurological damage
US5700825A (en) * 1995-03-31 1997-12-23 Florida State University Radiosensitizing diamines and their pharmaceutical preparations
US6060604A (en) 1995-03-31 2000-05-09 Florida State University Pharmaceutical compounds comprising polyamines substituted with electron-affinic groups
US5710171A (en) * 1995-05-24 1998-01-20 Merck & Co., Inc. Bisphenyl inhibitors of farnesyl-protein transferase
US6080870A (en) * 1996-04-03 2000-06-27 Merck & Co., Inc. Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US6063930A (en) * 1996-04-03 2000-05-16 Merck & Co., Inc. Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US6358060B2 (en) 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
DE19850301A1 (de) * 1998-10-30 2000-05-04 Basf Ag Verfahren zur Racematspaltung von 2-Hydroxypropionsäuren
EP1741709A1 (en) * 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
WO2016126957A1 (en) * 2015-02-04 2016-08-11 The Board Of Trustees Of The University Of Alabama Gas treating solutions containing imidazole-amine compounds

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
GB1341375A (en) * 1969-11-19 1973-12-19 Smith Kline French Lab Aminoalkylimidazoles and process for their production
DE2107487A1 (de) * 1970-02-26 1971-09-09 CIBA Geigy AG, Basel (Schweiz) Neue Amine und Verfahren zu ihrer Herstellung
DE2041771C3 (de) * 1970-08-22 1979-07-26 Bayer Ag, 5090 Leverkusen derivate
IE47132B1 (en) * 1977-08-19 1983-12-28 Roche Products Ltd Novel nitroimidazoles and pharmaceutical preparations containing these as well as their manufacture
EP0003732B1 (en) * 1978-02-01 1983-10-19 The Wellcome Foundation Limited Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof
JPS55313A (en) * 1978-06-13 1980-01-05 Kissei Pharmaceut Co Ltd Imidazole derivative
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen
US4338453A (en) * 1980-09-17 1982-07-06 The Upjohn Company Aminoalkyl-1,2,4-triazoles
US4404387A (en) * 1980-09-17 1983-09-13 The Upjohn Company Aminoalkyl-substituted imidazoles
JPS5769089A (en) * 1980-10-17 1982-04-27 Fuji Photo Film Co Ltd Desensitizer composition
DK162882A (da) * 1981-04-13 1982-10-14 Searle & Co Imidazolderivater eller syreadditionssalte deraf,deres fremstilling og anvendelse
GB2110663B (en) * 1981-12-04 1985-08-07 Farmos Group Ltd Imidazole derivatives
EP0105575B1 (en) * 1982-07-12 1987-03-04 G.D. Searle & Co. 1-(1h-imidazolyl), 1-n-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them
DE3238006A1 (de) * 1982-10-13 1984-04-19 Bayer Ag, 5090 Leverkusen Azolyl-methylamine, ihre herstellung und verwendung in mikrobiziden mitteln
EP0117462A3 (en) * 1983-02-28 1986-08-20 American Cyanamid Company N-(2-4-(1h-imidazol-1-yl)alkyl)arylamides
US4581370A (en) * 1983-07-12 1986-04-08 Schering A.G. Antiarrhythmic imidazoliums
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
GB8412750D0 (en) * 1984-05-18 1984-06-27 Ici Plc Heterocyclic compounds
US4728663A (en) * 1986-01-13 1988-03-01 American Cyanamid Company N-[(1H-imidazol-1-yl)alkyl]benz[cd]-indol-2-amines and use in inhibiting thromboxane synthetase enzyme
JPH0774205B2 (ja) * 1986-12-04 1995-08-09 三井石油化学工業株式会社 新規イミダゾ−ル誘導体
US4851423A (en) * 1986-12-10 1989-07-25 Schering Corporation Pharmaceutically active compounds
KR920701167A (ko) * 1989-07-07 1992-08-11 에릭 에스. 딕커 약제학적 활성 화합물
FR2656610B1 (fr) * 1989-12-29 1992-05-07 Sanofi Sa Derives d'amino-2 phenyl-4 thiazole, leur procede de preparation et leur application therapeutique.
EP0485890A3 (en) * 1990-11-16 1992-07-08 Hoechst Aktiengesellschaft Use of 2,3-disubstituate 1-azolyl-propane for inhibiting the pathogenic growth phase of dimorph yeast cell
FR2686084B1 (fr) * 1992-01-10 1995-12-22 Bioprojet Soc Civ Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques.

Also Published As

Publication number Publication date
IL104168A0 (en) 1993-05-13
PH30660A (en) 1997-09-16
HUT67372A (en) 1995-03-28
ES2131574T3 (es) 1999-08-01
AU3256393A (en) 1993-07-28
RU2118957C1 (ru) 1998-09-20
FI943020A0 (fi) 1994-06-22
RO113985B1 (ro) 1998-12-30
SK75294A3 (en) 1995-04-12
CN1037511C (zh) 1998-02-25
JPH07502519A (ja) 1995-03-16
HU9401453D0 (en) 1994-08-29
CZ153394A3 (en) 1995-10-18
PL172497B1 (pl) 1997-09-30
DE69229057D1 (de) 1999-06-02
NO942374L (no) 1994-06-22
IL104168A (en) 1999-04-11
AU656839B2 (en) 1995-02-16
HU211598A9 (en) 1995-12-28
NO942374D0 (ru) 1994-06-22
BG98812A (bg) 1995-05-31
EP0618907A1 (en) 1994-10-12
HRP921457A2 (en) 1996-02-29
NZ246336A (en) 1995-12-21
WO1993013075A1 (en) 1993-07-08
YU110592A (sh) 1996-01-08
ATE179416T1 (de) 1999-05-15
YU48294B (sh) 1998-05-15
DE69229057T2 (de) 1999-10-21
IN174436B (ru) 1994-12-03
EP0618907B1 (en) 1999-04-28
ZA929914B (en) 1993-06-23
GB9127304D0 (en) 1992-02-19
US5547972A (en) 1996-08-20
CN1096781A (zh) 1994-12-28
RU94030470A (ru) 1997-04-27
CA2126177A1 (en) 1993-07-08
MX9207491A (es) 1993-07-01
FI943020A (fi) 1994-06-22
JP2633087B2 (ja) 1997-07-23
SI9200411A (en) 1993-09-30

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