NO303119B1 - 2-substituerte sakkarinderivater med proteolytisk enzyminhiberende aktivitet, farmas÷ytisk preparat inneholdende disse derivatene, samt anvendelse derav - Google Patents
2-substituerte sakkarinderivater med proteolytisk enzyminhiberende aktivitet, farmas÷ytisk preparat inneholdende disse derivatene, samt anvendelse derav Download PDFInfo
- Publication number
- NO303119B1 NO303119B1 NO924401A NO924401A NO303119B1 NO 303119 B1 NO303119 B1 NO 303119B1 NO 924401 A NO924401 A NO 924401A NO 924401 A NO924401 A NO 924401A NO 303119 B1 NO303119 B1 NO 303119B1
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- Norway
- Prior art keywords
- isopropyl
- oxymethyl
- methoxysaccharin
- phenyl
- isopropylsaccharin
- Prior art date
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- JRMUNVKIHCOMHV-UHFFFAOYSA-M tetrabutylammonium bromide Chemical compound [Br-].CCCC[N+](CCCC)(CCCC)CCCC JRMUNVKIHCOMHV-UHFFFAOYSA-M 0.000 description 1
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- AXZWODMDQAVCJE-UHFFFAOYSA-L tin(II) chloride (anhydrous) Chemical compound [Cl-].[Cl-].[Sn+2] AXZWODMDQAVCJE-UHFFFAOYSA-L 0.000 description 1
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- 125000005270 trialkylamine group Chemical group 0.000 description 1
- 125000005034 trifluormethylthio group Chemical group FC(S*)(F)F 0.000 description 1
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- 125000001889 triflyl group Chemical group FC(F)(F)S(*)(=O)=O 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
- C07F9/6541—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/793,033 US5236917A (en) | 1989-05-04 | 1991-11-15 | Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof |
Publications (3)
Publication Number | Publication Date |
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NO924401D0 NO924401D0 (no) | 1992-11-13 |
NO924401L NO924401L (no) | 1993-05-18 |
NO303119B1 true NO303119B1 (no) | 1998-06-02 |
Family
ID=25158880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO924401A NO303119B1 (no) | 1991-11-15 | 1992-11-13 | 2-substituerte sakkarinderivater med proteolytisk enzyminhiberende aktivitet, farmas÷ytisk preparat inneholdende disse derivatene, samt anvendelse derav |
Country Status (17)
Country | Link |
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US (5) | US5236917A (ja) |
EP (1) | EP0542372A1 (ja) |
JP (1) | JPH05194444A (ja) |
KR (1) | KR930010015A (ja) |
AU (1) | AU654581B2 (ja) |
CA (1) | CA2079822A1 (ja) |
CZ (1) | CZ339092A3 (ja) |
FI (1) | FI925167A (ja) |
HU (2) | HUT66873A (ja) |
IL (1) | IL103748A (ja) |
MX (1) | MX9206008A (ja) |
MY (1) | MY107740A (ja) |
NO (1) | NO303119B1 (ja) |
NZ (1) | NZ244446A (ja) |
RU (1) | RU2101281C1 (ja) |
SG (1) | SG55181A1 (ja) |
TW (1) | TW221433B (ja) |
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US5250696A (en) * | 1990-11-01 | 1993-10-05 | Sterling Winthrop Inc. | 2-saccharinylmethyl aryl carboxylate |
US5187173A (en) * | 1991-12-27 | 1993-02-16 | Sterling Winthrop Inc. | 2-saccharinylmethyl and 4,5,6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates useful as proteolytic enzyme inhibitors and compositions and method of use thereof |
JPH07200419A (ja) * | 1993-12-28 | 1995-08-04 | Nec Corp | バスインタフェース装置 |
-
1991
- 1991-11-15 US US07/793,033 patent/US5236917A/en not_active Expired - Fee Related
-
1992
- 1992-09-23 TW TW081107529A patent/TW221433B/zh active
- 1992-09-25 AU AU25340/92A patent/AU654581B2/en not_active Ceased
- 1992-10-05 CA CA002079822A patent/CA2079822A1/en not_active Abandoned
- 1992-10-19 MX MX9206008A patent/MX9206008A/es unknown
- 1992-11-12 EP EP92203469A patent/EP0542372A1/en not_active Withdrawn
- 1992-11-13 NZ NZ244446A patent/NZ244446A/en unknown
- 1992-11-13 RU RU92004381A patent/RU2101281C1/ru active
- 1992-11-13 IL IL10374892A patent/IL103748A/xx not_active IP Right Cessation
- 1992-11-13 NO NO924401A patent/NO303119B1/no unknown
- 1992-11-13 HU HU9203566A patent/HUT66873A/hu unknown
- 1992-11-13 FI FI925167A patent/FI925167A/fi unknown
- 1992-11-13 CZ CS923390A patent/CZ339092A3/cs unknown
- 1992-11-14 KR KR1019920021437A patent/KR930010015A/ko not_active Application Discontinuation
- 1992-11-14 MY MYPI92002080A patent/MY107740A/en unknown
- 1992-11-16 JP JP4305295A patent/JPH05194444A/ja not_active Withdrawn
- 1992-12-11 SG SG1996008996A patent/SG55181A1/en unknown
-
1993
- 1993-05-24 US US08/067,637 patent/US5371074A/en not_active Expired - Fee Related
-
1994
- 1994-07-05 US US08/270,964 patent/US5650422A/en not_active Expired - Fee Related
-
1995
- 1995-05-24 US US08/449,152 patent/US5596012A/en not_active Expired - Fee Related
- 1995-06-30 HU HU95P/P00637P patent/HU211663A9/hu unknown
-
1997
- 1997-02-20 US US08/803,297 patent/US5874432A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5650422A (en) | 1997-07-22 |
US5371074A (en) | 1994-12-06 |
US5236917A (en) | 1993-08-17 |
MX9206008A (es) | 1993-11-01 |
US5874432A (en) | 1999-02-23 |
TW221433B (ja) | 1994-03-01 |
EP0542372A1 (en) | 1993-05-19 |
CA2079822A1 (en) | 1993-05-16 |
JPH05194444A (ja) | 1993-08-03 |
IL103748A (en) | 1997-02-18 |
FI925167A0 (fi) | 1992-11-13 |
SG55181A1 (en) | 1998-12-21 |
HU211663A9 (en) | 1995-12-28 |
NO924401L (no) | 1993-05-18 |
FI925167A (fi) | 1993-05-16 |
HU9203566D0 (en) | 1993-01-28 |
NZ244446A (en) | 1994-09-27 |
KR930010015A (ko) | 1993-06-21 |
IL103748A0 (en) | 1993-04-04 |
RU2101281C1 (ru) | 1998-01-10 |
AU654581B2 (en) | 1994-11-10 |
CZ339092A3 (en) | 1993-06-16 |
US5596012A (en) | 1997-01-21 |
HUT66873A (en) | 1995-01-30 |
NO924401D0 (no) | 1992-11-13 |
MY107740A (en) | 1996-05-30 |
AU2534092A (en) | 1993-05-20 |
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