NO20091793L - 2-pyridinkarboksamidderivat med GK-aktiverende virkning - Google Patents
2-pyridinkarboksamidderivat med GK-aktiverende virkningInfo
- Publication number
- NO20091793L NO20091793L NO20091793A NO20091793A NO20091793L NO 20091793 L NO20091793 L NO 20091793L NO 20091793 A NO20091793 A NO 20091793A NO 20091793 A NO20091793 A NO 20091793A NO 20091793 L NO20091793 L NO 20091793L
- Authority
- NO
- Norway
- Prior art keywords
- nitrogen
- activating effect
- lower alkyl
- independently represent
- alkyl group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Child & Adolescent Psychology (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
eller et farmasøytisk akseptabelt salt derav som har glukokinase-aktiverende aktivitet og som følgelig er anvendbar for behandling av diabetes eller fedme. (I) hvori R1 og R2 uavhengig av hverandre står for en lavere alkylgruppe, og Xi står for en gruppe representert ved formel (II-l) : hvori R11 og R12 uavhengig av hverandre står for et hydrogenatom eller en lavere alkylgruppe, eller R11 og R12 sammen med nitrogenatomet som R11 og R12 er bundet til, kan danne en nitrogenholdig, alifatisk ring med 4 til 7 medlemmer (hvori ett av karbonatomene som inngår i den nitrogenholdige, alifatiske
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006275824 | 2006-10-06 | ||
PCT/JP2007/070014 WO2008044777A1 (en) | 2006-10-06 | 2007-10-05 | 2-pyridinecarboxamide derivative having gk-activating activity |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20091793L true NO20091793L (no) | 2009-05-05 |
Family
ID=39282963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20091793A NO20091793L (no) | 2006-10-06 | 2009-05-05 | 2-pyridinkarboksamidderivat med GK-aktiverende virkning |
Country Status (22)
Country | Link |
---|---|
US (1) | US8338460B2 (no) |
EP (1) | EP2077266B1 (no) |
JP (1) | JP5292100B2 (no) |
KR (1) | KR20090060426A (no) |
CN (1) | CN101522673A (no) |
AR (1) | AR063028A1 (no) |
AU (1) | AU2007307560B2 (no) |
BR (1) | BRPI0716590A2 (no) |
CA (1) | CA2667068C (no) |
CL (1) | CL2007002890A1 (no) |
CO (1) | CO6180507A2 (no) |
CR (1) | CR10673A (no) |
GT (1) | GT200900065A (no) |
IL (1) | IL197714A0 (no) |
MA (1) | MA30813B1 (no) |
MX (1) | MX2009003073A (no) |
NO (1) | NO20091793L (no) |
PE (1) | PE20081195A1 (no) |
RU (1) | RU2009117209A (no) |
SV (1) | SV2009003196A (no) |
TW (1) | TW200831504A (no) |
WO (1) | WO2008044777A1 (no) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ540791A (en) * | 2003-02-13 | 2009-09-25 | Banyu Pharma Co Ltd | Novel 2-pyridinecarboxamide derivatives |
AR063028A1 (es) | 2006-10-06 | 2008-12-23 | Banyu Pharma Co Ltd | Derivados heterociclicos de piridin-2-carboxamida activadores de glucoquinasas, utiles para el tratamiento de diabetes y obesidad y composiciones farmaceuticas que los contienen. |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
CA2705370C (en) | 2007-11-12 | 2015-10-13 | Banyu Pharmaceutical Co., Ltd. | Heteroaryloxy quinazoline derivatives |
AU2009280579A1 (en) | 2008-08-15 | 2010-02-18 | Banyu Pharmaceutical Co.,Ltd. | Acetyl pyrrolidinyl indole derivative |
US8609699B2 (en) * | 2008-08-29 | 2013-12-17 | Msd K.K. | Oxotetrahydrofuran-2-yl-benzimidazole derivative |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
US9527838B2 (en) | 2012-12-17 | 2016-12-27 | Merck Sharp & Dohme Corp. | 2-pyridinecarboxamide derivatives, compositions containing such compounds, and methods of treatment |
CN113045546A (zh) * | 2021-03-25 | 2021-06-29 | 浙江天宇药业股份有限公司 | 一种吡咯替尼杂质、其制备方法及用途 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
US3630200A (en) | 1969-06-09 | 1971-12-28 | Alza Corp | Ocular insert |
US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
GB2277930A (en) | 1993-05-11 | 1994-11-16 | Shell Int Research | Herbicidal picolinamide derivatives |
US6022884A (en) | 1997-11-07 | 2000-02-08 | Amgen Inc. | Substituted pyridine compounds and methods of use |
SE0102300D0 (sv) | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
SE519859C2 (sv) | 2001-08-17 | 2003-04-15 | Novacast Ab | Anordning för behandling av järnlegeringar i ett kärl |
SE0102764D0 (sv) | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
JP4419571B2 (ja) * | 2002-03-26 | 2010-02-24 | 萬有製薬株式会社 | 新規アミノベンズアミド誘導体 |
NZ540791A (en) | 2003-02-13 | 2009-09-25 | Banyu Pharma Co Ltd | Novel 2-pyridinecarboxamide derivatives |
CA2516407C (en) | 2003-02-26 | 2013-07-09 | Banyu Pharmaceutical Co., Ltd. | Heteroarylcarbamoylbenzene derivatives |
PL2256106T3 (pl) | 2003-07-22 | 2015-08-31 | Astex Therapeutics Ltd | Związki 3,4-pochodne 1h-pirazolu i ich zastosowanie jako kinazy zależne od cyklin (cdk) i modulatory kinazy syntazy glikogenu-3 (gsk-3) |
US20050176767A1 (en) | 2003-10-30 | 2005-08-11 | Laval Chan Chun Kong | Pyridine carboxamide and methods for inhibiting HIV integrase |
US7435831B2 (en) | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
GB0412468D0 (en) | 2004-06-04 | 2004-07-07 | Astrazeneca Ab | Chemical compounds |
KR100716891B1 (ko) | 2005-11-01 | 2007-05-09 | (주)아모레퍼시픽 | 피리딘 티아졸 카복사마이드 유도체, 이의 제조방법 및이를 함유하는 피부 미백용 조성물 |
US7951824B2 (en) | 2006-02-17 | 2011-05-31 | Hoffman-La Roche Inc. | 4-aryl-pyridine-2-carboxyamide derivatives |
EP1849785A1 (en) | 2006-04-28 | 2007-10-31 | Neuropharma, S.A. | N-(2-Thiazolyl)-amide derivatives as GSK-3 inhibitors |
AR063028A1 (es) | 2006-10-06 | 2008-12-23 | Banyu Pharma Co Ltd | Derivados heterociclicos de piridin-2-carboxamida activadores de glucoquinasas, utiles para el tratamiento de diabetes y obesidad y composiciones farmaceuticas que los contienen. |
-
2007
- 2007-09-27 AR ARP070104280A patent/AR063028A1/es not_active Application Discontinuation
- 2007-10-04 PE PE2007001346A patent/PE20081195A1/es not_active Application Discontinuation
- 2007-10-05 MX MX2009003073A patent/MX2009003073A/es active IP Right Grant
- 2007-10-05 BR BRPI0716590-0A patent/BRPI0716590A2/pt not_active IP Right Cessation
- 2007-10-05 CL CL2007002890A patent/CL2007002890A1/es unknown
- 2007-10-05 KR KR1020097006965A patent/KR20090060426A/ko not_active Application Discontinuation
- 2007-10-05 EP EP07829750A patent/EP2077266B1/en active Active
- 2007-10-05 WO PCT/JP2007/070014 patent/WO2008044777A1/ja active Application Filing
- 2007-10-05 US US11/973,240 patent/US8338460B2/en active Active
- 2007-10-05 RU RU2009117209/04A patent/RU2009117209A/ru not_active Application Discontinuation
- 2007-10-05 CN CNA2007800374154A patent/CN101522673A/zh active Pending
- 2007-10-05 JP JP2008538775A patent/JP5292100B2/ja not_active Expired - Fee Related
- 2007-10-05 TW TW096137610A patent/TW200831504A/zh unknown
- 2007-10-05 AU AU2007307560A patent/AU2007307560B2/en not_active Ceased
- 2007-10-05 CA CA2667068A patent/CA2667068C/en not_active Expired - Fee Related
-
2009
- 2009-03-19 CO CO09028706A patent/CO6180507A2/es not_active Application Discontinuation
- 2009-03-19 IL IL197714A patent/IL197714A0/en unknown
- 2009-03-19 CR CR10673A patent/CR10673A/es unknown
- 2009-03-20 GT GT200900065A patent/GT200900065A/es unknown
- 2009-03-20 SV SV2009003196A patent/SV2009003196A/es not_active Application Discontinuation
- 2009-04-24 MA MA31819A patent/MA30813B1/fr unknown
- 2009-05-05 NO NO20091793A patent/NO20091793L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
SV2009003196A (es) | 2009-07-28 |
US20080090799A1 (en) | 2008-04-17 |
MA30813B1 (fr) | 2009-10-01 |
US8338460B2 (en) | 2012-12-25 |
WO2008044777A1 (en) | 2008-04-17 |
JPWO2008044777A1 (ja) | 2010-02-18 |
EP2077266B1 (en) | 2012-07-25 |
EP2077266A1 (en) | 2009-07-08 |
KR20090060426A (ko) | 2009-06-12 |
CO6180507A2 (es) | 2010-07-19 |
AU2007307560A1 (en) | 2008-04-17 |
RU2009117209A (ru) | 2010-11-20 |
IL197714A0 (en) | 2009-12-24 |
CA2667068C (en) | 2012-03-27 |
GT200900065A (es) | 2010-04-28 |
TW200831504A (en) | 2008-08-01 |
JP5292100B2 (ja) | 2013-09-18 |
CR10673A (es) | 2009-09-03 |
CA2667068A1 (en) | 2008-04-17 |
AR063028A1 (es) | 2008-12-23 |
AU2007307560B2 (en) | 2012-10-04 |
CN101522673A (zh) | 2009-09-02 |
EP2077266A4 (en) | 2010-07-07 |
MX2009003073A (es) | 2009-04-02 |
CL2007002890A1 (es) | 2008-01-18 |
BRPI0716590A2 (pt) | 2012-12-25 |
PE20081195A1 (es) | 2008-09-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |