NO20090896L - Farmakokinetisk forbedrede forbindelser - Google Patents

Farmakokinetisk forbedrede forbindelser

Info

Publication number
NO20090896L
NO20090896L NO20090896A NO20090896A NO20090896L NO 20090896 L NO20090896 L NO 20090896L NO 20090896 A NO20090896 A NO 20090896A NO 20090896 A NO20090896 A NO 20090896A NO 20090896 L NO20090896 L NO 20090896L
Authority
NO
Norway
Prior art keywords
improved compounds
pharmacokinetically improved
pharmacokinetically
compounds
stereoisomer
Prior art date
Application number
NO20090896A
Other languages
English (en)
Inventor
Steven Kates
Paul Sweetnam
Stewart Campbell
David Duffy
Michael Grogan
Emanuele Ostuni
Olivier Schueller
Original Assignee
Surface Logix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surface Logix Inc filed Critical Surface Logix Inc
Publication of NO20090896L publication Critical patent/NO20090896L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/08—Six-membered rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Vascular Medicine (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Tilveiebrakt er en forbindelse med formel A som har forbedret uspesifikk bindingskarakteristika og farmakokinetiske egenskaper: (A) eller et farmasøytisk akseptabelt salt, stereoisomer eller hydrat derav.
NO20090896A 2006-08-24 2009-02-26 Farmakokinetisk forbedrede forbindelser NO20090896L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84030606P 2006-08-24 2006-08-24
PCT/US2007/018784 WO2008024494A2 (en) 2006-08-24 2007-08-23 Pharmacokinetically improved compounds

Publications (1)

Publication Number Publication Date
NO20090896L true NO20090896L (no) 2009-03-09

Family

ID=39107450

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090896A NO20090896L (no) 2006-08-24 2009-02-26 Farmakokinetisk forbedrede forbindelser

Country Status (15)

Country Link
US (2) US20100324037A1 (no)
EP (2) EP2705753A1 (no)
JP (2) JP2010501577A (no)
KR (1) KR20090042863A (no)
CN (1) CN101528042A (no)
AU (1) AU2007287024A1 (no)
BR (1) BRPI0716571A2 (no)
CA (1) CA2661483A1 (no)
ES (1) ES2548759T3 (no)
IL (1) IL197224A0 (no)
MX (1) MX2009002073A (no)
NO (1) NO20090896L (no)
TW (1) TW200826944A (no)
WO (1) WO2008024494A2 (no)
ZA (1) ZA200901462B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CR9465A (es) * 2005-03-25 2008-06-19 Surface Logix Inc Compuestos mejorados farmacocineticamente
US9573956B2 (en) 2013-03-01 2017-02-21 Fundación Para La Investigación Médica Aplicada Compounds as dual inhibitors of phosphodiesterases and histone deacetylases
WO2016147659A1 (en) * 2015-03-16 2016-09-22 Sumitomo Dainippon Pharma Co., Ltd. Bicyclic imidazolo derivative
CN114085225A (zh) * 2021-06-04 2022-02-25 广东西捷药业有限公司 一种伐地那非类似物及其合成方法和应用
TWI806144B (zh) * 2021-09-01 2023-06-21 臺灣塑膠工業股份有限公司 纖維預浸布的含浸裝置及其方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
JPH05501611A (ja) 1989-11-13 1993-03-25 アフィマックス　テクノロジーズ　ナームロゼ　ベノートスハップ 表面上への抗リガンドの空間的アドレス可能な固定化
DE69133293T2 (de) 1990-12-06 2004-05-27 Affymetrix, Inc., Santa Clara Verfahren und Reagenzien für immobilisierten Polymersynthese in sehr grossem Masstab
ATE262374T1 (de) 1991-11-22 2004-04-15 Affymetrix Inc Kombinatorische strategien für polymersynthese
US5359115A (en) * 1992-03-26 1994-10-25 Affymax Technologies, N.V. Methods for the synthesis of phosphonate esters
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
JP2857540B2 (ja) 1992-06-22 1999-02-17 ファナック株式会社 カッタパスの自動再作成を行うｃａｄ／ｃａｍ方法及び装置
US5288514A (en) * 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
HUT72495A (en) 1992-10-01 1996-05-28 Cold Spring Harbor Lab Complex combinatorial chemical libraries encoded with tags
US5480971A (en) * 1993-06-17 1996-01-02 Houghten Pharmaceuticals, Inc. Peralkylated oligopeptide mixtures
US5440016A (en) 1993-06-18 1995-08-08 Torrey Pines Institute For Molecular Studies Peptides of the formula (KFmoc) ZZZ and their uses
US5362899A (en) * 1993-09-09 1994-11-08 Affymax Technologies, N.V. Chiral synthesis of alpha-aminophosponic acids
CN100430396C (zh) * 1997-11-12 2008-11-05 拜耳医药保健股份公司 用作磷酸二酯酶抑制剂的2-苯基取代的咪唑并三嗪酮
DE19827640A1 (de) * 1998-06-20 1999-12-23 Bayer Ag 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
US6451807B1 (en) * 1999-04-30 2002-09-17 Lilly Icos, Llc. Methods of treating sexual dysfunction in an individual suffering from a retinal disease, class 1 congestive heart failure, or myocardial infarction using a PDE5 inhibitor
EP1244673A2 (de) * 1999-12-24 2002-10-02 Bayer Aktiengesellschaft Imidazo[1,3,5]triazinone und ihre verwendung
US6699665B1 (en) 2000-11-08 2004-03-02 Surface Logix, Inc. Multiple array system for integrating bioarrays
DE10107639A1 (de) * 2001-02-15 2002-08-22 Bayer Ag 2-Alkoxyphenyl-substituierte Imidazotriazinone
WO2003012392A2 (en) 2001-07-27 2003-02-13 Surface Logix, Inc. Resealable and sealable devices for biochemical assays
CA2458844A1 (en) 2001-08-27 2003-03-06 Surface Logix, Inc. Immobilization of biological molecules onto surfaces coated with monolayers
DE10162435A1 (de) 2001-12-19 2003-07-17 Joerg Lahann Verfahren zur Erzeugung von Oberflächenbeschichtungen, die die Adsorption von Proteinen bzw. die Adhäsion von Bakterien und/oder Zellen vermindern
CA2485984A1 (en) * 2002-05-23 2003-12-04 Pfizer Inc. Pharmaceutical combination of pde5 inhibitors with ace inhibitors
DE102004038328A1 (de) * 2004-08-06 2006-03-16 Bayer Healthcare Ag Neue Verwendungen von 2-Phenyl-substituierten Imidazotriazinon-Derivaten
MX2007010142A (es) * 2005-02-18 2007-12-07 Surface Logix Inc Metodos para fabricar compuestos mejorados farmacocineticamente que comprenden residuos o grupos funcionales y composiciones farmaceuticas que comprenden dichos compuestos.
CR9465A (es) * 2005-03-25 2008-06-19 Surface Logix Inc Compuestos mejorados farmacocineticamente

Also Published As

Publication number Publication date
US8853394B2 (en) 2014-10-07
WO2008024494A3 (en) 2008-04-10
EP2705753A1 (en) 2014-03-12
ZA200901462B (en) 2010-07-28
JP2010501577A (ja) 2010-01-21
CN101528042A (zh) 2009-09-09
IL197224A0 (en) 2009-12-24
US20130096114A1 (en) 2013-04-18
ES2548759T3 (es) 2015-10-20
US20100324037A1 (en) 2010-12-23
TW200826944A (en) 2008-07-01
AU2007287024A1 (en) 2008-02-28
BRPI0716571A2 (pt) 2013-11-05
EP2061322B1 (en) 2015-07-01
CA2661483A1 (en) 2008-02-28
KR20090042863A (ko) 2009-04-30
MX2009002073A (es) 2009-05-25
EP2061322A2 (en) 2009-05-27
JP2014055136A (ja) 2014-03-27
WO2008024494A2 (en) 2008-02-28
EP2061322A4 (en) 2011-01-05
WO2008024494A9 (en) 2009-04-02

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