NO20090726L - N-(aminoheteroaryl)-1H-indol-2-karboksamidderivater, fremstilling derav og terapeutisk anvendelse derav - Google Patents
N-(aminoheteroaryl)-1H-indol-2-karboksamidderivater, fremstilling derav og terapeutisk anvendelse deravInfo
- Publication number
- NO20090726L NO20090726L NO20090726A NO20090726A NO20090726L NO 20090726 L NO20090726 L NO 20090726L NO 20090726 A NO20090726 A NO 20090726A NO 20090726 A NO20090726 A NO 20090726A NO 20090726 L NO20090726 L NO 20090726L
- Authority
- NO
- Norway
- Prior art keywords
- cycloalkyl
- aryl
- alkylene
- alkyl
- heteroaryl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Det beskrives forbindelser med den generelle formel (I) der X1 er et hydrogen eller halogenatom eller en C1-C6-alkyl, C3-C7-sykloalkyl, C3-C7sykloalkyl-C1-C3-alkylen, C1-C6-fluoralkyl, cyano, C(O)NR1R2, nitro, C1-C6-tioalkyl, S(O)-C1-C6-alkyI, -S(O)2-C1-C6-alkyl, SO2NR1R2, aryl-C1-C6-alkylen, aryl eller heteroarylgruppe der aryl og heteroaryl eventuelt er substituert ; X2 er et hydrogen eller halogenatom eller en C1-C6-alkyl, C3-C7-sykloalkyl, C3-C7-sykloalkyl-C1-C3-alkylen, C1-C6-fluoralkyl, C1-C6-alkoksyl, C3-C7-sykloalkyl-C1-C6-alkylen-O-, C1-C6fluoralkoksyl, cyano, C(O)NR1R2, C1-C6-tioalkyl, -S(O)-C1-C6-alkyl, -S(O)2-C1-C6alkyl, SO2NR1R2, aryl-C1-C6-alkylen, aryl eller heteroarylgruppe der aryl og heteroaryl eventulet er substituert; X3 og X4 uavhengig av hverandre er et hydrogen eller halogenatom eller en C1-C6-alkyl, C3-C7-sykloalkyl, C3-C7-sykloalkyl-C1-C3-alkylen, C1-C6-fluoralkyl, C1-C6-alkoksyl, C3-C7-sykloalkyl-C1-C6-alkylen-O-, C1-C6 fluoralkoksyl, cyano, C(O)NR1R2, nitro, NR1R2, C1-C6-tioalkyl, -S(O)-C1-C6-alkyl, S(O)2-C1-C6-alkyl, SO2NR1R2, NR3COR4, NR3SO2R5, aryl-C1-C6-alkylen, aryl eller heteroarylgruppe der aryl og heteroaryl eventuelt er substituert ; Z1, Z2, Z3, Z4 uavhengig av hverandre er et nitrogenatom eller en C(R6) gruppe; n er lik 0, 1, 2 eller 3; Y er eventuelt substituert aryl eller heteroaryl; Ra og Rb uavhengig av hverandre er et hydrogenatom eller en C1-C6-alkyl, C3-C7-sykloalkyl, C3-C7-sykloalkyl-C1-C3-alkylen, C1-C6-fluoralkyl, hydroksyl, C1-C6-alkoksyl, C3-C7-sykloalkyl-C1-C6-alkylen-O-, C1-C6-fluoalkoksyl, aryl eller heteroarylgruppe, der Ra og Rb eventuelt er substituert; i form av en base eller et addisjonssalt med en syre, eller i form av et hydrat eller et solvat. Videre beskrives forbindelsenes fremstilling og deres terapeutiske bruk.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0606742A FR2903985B1 (fr) | 2006-07-24 | 2006-07-24 | Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique |
| PCT/FR2007/001250 WO2008012418A1 (fr) | 2006-07-24 | 2007-07-20 | Derives de n- (amino-heteroaryl) - 1h-indole-2 -carboxamides comme antagonistes des recepteurs de type trpv1 ou vr1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20090726L true NO20090726L (no) | 2009-02-25 |
Family
ID=37734283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20090726A NO20090726L (no) | 2006-07-24 | 2009-02-13 | N-(aminoheteroaryl)-1H-indol-2-karboksamidderivater, fremstilling derav og terapeutisk anvendelse derav |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US8227489B2 (no) |
| EP (1) | EP2046775B1 (no) |
| JP (1) | JP5265541B2 (no) |
| KR (1) | KR20090042239A (no) |
| CN (1) | CN101495469B (no) |
| AR (1) | AR061946A1 (no) |
| AU (1) | AU2007279166C1 (no) |
| BR (1) | BRPI0714559A2 (no) |
| CA (1) | CA2656716C (no) |
| CO (1) | CO6150146A2 (no) |
| CY (1) | CY1113470T1 (no) |
| DK (1) | DK2046775T3 (no) |
| EA (1) | EA016829B1 (no) |
| ES (1) | ES2393630T3 (no) |
| FR (1) | FR2903985B1 (no) |
| IL (1) | IL196113A0 (no) |
| MA (1) | MA30694B1 (no) |
| ME (1) | ME00584A (no) |
| MX (1) | MX2009000649A (no) |
| MY (1) | MY147465A (no) |
| NO (1) | NO20090726L (no) |
| NZ (1) | NZ574265A (no) |
| PE (1) | PE20080947A1 (no) |
| PL (1) | PL2046775T3 (no) |
| PT (1) | PT2046775E (no) |
| SI (1) | SI2046775T1 (no) |
| TW (1) | TWI388554B (no) |
| WO (1) | WO2008012418A1 (no) |
| ZA (1) | ZA200900228B (no) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2926553B1 (fr) * | 2008-01-23 | 2010-02-19 | Sanofi Aventis | Derives d'indole-2-carboxamides et d'azaindole-2- carboxamides substitues par un groupe silanyle, leur preparation et leur application en therapeutique |
| CA2857344C (en) | 2011-12-21 | 2019-02-12 | Novira Therapeutics, Inc. | Hepatitis b antiviral agents |
| SG10201605291WA (en) | 2012-08-28 | 2016-08-30 | Janssen Sciences Ireland Uc | Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b |
| HUE034820T2 (en) | 2013-02-28 | 2018-02-28 | Janssen Sciences Ireland Uc | Sulphamoyl arylamides and their use as medicaments for the treatment of hepatitis B |
| EA027068B1 (ru) | 2013-04-03 | 2017-06-30 | Янссен Сайенсиз Айрлэнд Юси | Производные n-фенилкарбоксамида и их применение в качестве лекарственных препаратов для лечения гепатита b |
| WO2014184365A1 (en) | 2013-05-17 | 2014-11-20 | Janssen R&D Ireland | Sulphamoylthiophenamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| JO3603B1 (ar) | 2013-05-17 | 2020-07-05 | Janssen Sciences Ireland Uc | مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي |
| TR201807090T4 (tr) | 2013-07-25 | 2018-06-21 | Janssen Sciences Ireland Uc | Glioksamid sübstitüeli pirrolamid deriveleri ve bunun hepatitin tedavisine yönelik ilaçlar olarak kullanımı. |
| WO2015059212A1 (en) | 2013-10-23 | 2015-04-30 | Janssen R&D Ireland | Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| US10392349B2 (en) | 2014-01-16 | 2019-08-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| US9169212B2 (en) | 2014-01-16 | 2015-10-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| AU2015214096B2 (en) | 2014-02-05 | 2021-02-11 | Novira Therapeutics, Inc. | Combination therapy for treatment of HBV infections |
| CN110483484A (zh) | 2014-02-06 | 2019-11-22 | 爱尔兰詹森科学公司 | 氨磺酰基吡咯酰胺衍生物及其作为药物用于治疗乙型肝炎的用途 |
| JP2018510159A (ja) | 2015-03-19 | 2018-04-12 | ノヴィラ・セラピューティクス・インコーポレイテッド | アゾカン及びアゾナン誘導体及びｂ型肝炎感染症の治療法 |
| US10875876B2 (en) | 2015-07-02 | 2020-12-29 | Janssen Sciences Ireland Uc | Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B |
| PL3319959T3 (pl) | 2015-07-06 | 2022-02-14 | Alkermes, Inc. | Hetero-haloinhibitory deacetylazy histonowej |
| WO2017007755A1 (en) | 2015-07-06 | 2017-01-12 | Rodin Therapeutics, Inc. | Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase |
| CN105295896B (zh) * | 2015-09-11 | 2017-12-29 | 浙江大学 | 一种特异性标记的辣椒素荧光探针及其合成方法和应用 |
| CA3000197A1 (en) | 2015-09-29 | 2017-04-06 | Novira Therapeutics, Inc. | Crystalline forms of a hepatitis b antiviral agent |
| EP3848026A1 (en) | 2016-04-15 | 2021-07-14 | Novira Therapeutics Inc. | Combinations and methods comprising a capsid assembly inhibitor |
| EP3568135B1 (en) | 2017-01-11 | 2021-04-07 | Alkermes, Inc. | Bicyclic inhibitors of histone deacetylase |
| JP7152471B2 (ja) | 2017-08-07 | 2022-10-12 | ロダン・セラピューティクス，インコーポレーテッド | ヒストン脱アセチル化酵素の二環阻害剤 |
| MA52019A (fr) | 2018-03-14 | 2021-01-20 | Janssen Sciences Ireland Unlimited Co | Schéma posologique de modulateur d'assemblage de capside |
| JP2022521081A (ja) | 2019-02-22 | 2022-04-05 | ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー | Ｈｂｖ感染若しくはｈｂｖ誘導性疾患の治療において有用なアミド誘導体 |
| CN113795486A (zh) | 2019-05-06 | 2021-12-14 | 爱尔兰詹森科学公司 | 用于治疗hbv感染或hbv诱发的疾病的酰胺衍生物 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL248308A (no) | 1958-09-30 | |||
| US4104385A (en) | 1976-08-19 | 1978-08-01 | Sterling Drug Inc. | Cyclic alkylidenyl N-[6-(amino)-3-pyridazinyl]aminomethylenemalonates |
| JPS609062B2 (ja) * | 1977-08-03 | 1985-03-07 | 広栄化学工業株式会社 | 新規な２−置換アミノ−５−γ−ピコリン類またはこれらの塩およびそれらの製造法とそれらを含有する角質繊維用染料 |
| ES2249384T3 (es) | 2000-12-12 | 2006-04-01 | Neurogen Corporation | Espiro(isobenzofuran-1,4'-piperadin)-3-onas y 3h-espirobenzofuran-1,4-piperidinas. |
| DE10147672A1 (de) * | 2001-09-27 | 2003-04-10 | Bayer Ag | Substituierte 2,5-Diamidoindole und ihre Verwendung |
| PE20040801A1 (es) | 2002-12-12 | 2004-11-25 | Hoffmann La Roche | Derivados de pirazina y piridina 5-sustituidos como activadores de glucoquinasa |
| CA2510811A1 (en) * | 2002-12-20 | 2004-07-08 | Bayer Healthcare Ag | Use of substituted 2,5-diamidoindoles for the treatment of urological diseases |
| WO2004062665A1 (en) | 2003-01-16 | 2004-07-29 | Sb Pharmco Puerto Rico Inc | Heteroaryl- substituted pyrrolo` 2, 3- b! pyridine derivatives as crf receptor antagonists |
| EP1438956A1 (en) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
| GB0314136D0 (en) | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| TWI341838B (en) | 2003-09-17 | 2011-05-11 | Ono Pharmaceutical Co | Carboxylic acid compound and pharmaceutical composition containg same as active ingredient |
| GB0322016D0 (en) * | 2003-09-19 | 2003-10-22 | Merck Sharp & Dohme | New compounds |
| EP1673355A1 (en) | 2003-09-22 | 2006-06-28 | Pfizer Limited | Substituted triazole derivatives as oxytocin antagonists |
| WO2005035526A1 (en) | 2003-10-09 | 2005-04-21 | Argenta Discovery Ltd. | Bicyclic compounds and their therapeutic use |
| WO2006040522A1 (en) | 2004-10-12 | 2006-04-20 | Astrazeneca Ab | Quinoline derivatives |
| FR2880625B1 (fr) * | 2005-01-07 | 2007-03-09 | Sanofi Aventis Sa | Derives de n-(heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique |
| US20080221107A1 (en) | 2005-07-15 | 2008-09-11 | Astrazeneca Ab | Therapeutic Agents |
| WO2007060140A2 (en) | 2005-11-28 | 2007-05-31 | F. Hoffmann-La Roche Ag | Inhibitors of diacyglycerol acyltransferase (dgat) |
-
2006
- 2006-07-24 FR FR0606742A patent/FR2903985B1/fr not_active Expired - Fee Related
-
2007
- 2007-07-19 TW TW096126382A patent/TWI388554B/zh not_active IP Right Cessation
- 2007-07-20 AR ARP070103239A patent/AR061946A1/es not_active Application Discontinuation
- 2007-07-20 ES ES07823311T patent/ES2393630T3/es active Active
- 2007-07-20 JP JP2009521291A patent/JP5265541B2/ja not_active Expired - Fee Related
- 2007-07-20 NZ NZ574265A patent/NZ574265A/en not_active IP Right Cessation
- 2007-07-20 MY MYPI20090316A patent/MY147465A/en unknown
- 2007-07-20 MX MX2009000649A patent/MX2009000649A/es active IP Right Grant
- 2007-07-20 EP EP07823311A patent/EP2046775B1/fr active Active
- 2007-07-20 ME MEP-18/09A patent/ME00584A/xx unknown
- 2007-07-20 PL PL07823311T patent/PL2046775T3/pl unknown
- 2007-07-20 AU AU2007279166A patent/AU2007279166C1/en not_active Ceased
- 2007-07-20 PT PT07823311T patent/PT2046775E/pt unknown
- 2007-07-20 CA CA2656716A patent/CA2656716C/fr not_active Expired - Fee Related
- 2007-07-20 CN CN200780028161XA patent/CN101495469B/zh not_active Expired - Fee Related
- 2007-07-20 PE PE2007000947A patent/PE20080947A1/es not_active Application Discontinuation
- 2007-07-20 KR KR1020097001656A patent/KR20090042239A/ko not_active Application Discontinuation
- 2007-07-20 WO PCT/FR2007/001250 patent/WO2008012418A1/fr active Application Filing
- 2007-07-20 DK DK07823311.1T patent/DK2046775T3/da active
- 2007-07-20 SI SI200731056T patent/SI2046775T1/sl unknown
- 2007-07-20 BR BRPI0714559-4A2A patent/BRPI0714559A2/pt not_active IP Right Cessation
- 2007-07-20 ZA ZA200900228A patent/ZA200900228B/xx unknown
- 2007-07-20 EA EA200970149A patent/EA016829B1/ru not_active IP Right Cessation
-
2008
- 2008-12-22 IL IL196113A patent/IL196113A0/en not_active IP Right Cessation
-
2009
- 2009-01-15 CO CO09002769A patent/CO6150146A2/es unknown
- 2009-01-23 US US12/358,639 patent/US8227489B2/en not_active Expired - Fee Related
- 2009-02-13 NO NO20090726A patent/NO20090726L/no not_active Application Discontinuation
- 2009-02-13 MA MA31637A patent/MA30694B1/fr unknown
-
2012
- 2012-06-22 US US13/530,261 patent/US8481745B2/en not_active Expired - Fee Related
- 2012-11-08 CY CY20121101063T patent/CY1113470T1/el unknown
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