NO20085033L - Rutenium II forbindelser - Google Patents

Rutenium II forbindelser

Info

Publication number
NO20085033L
NO20085033L NO20085033A NO20085033A NO20085033L NO 20085033 L NO20085033 L NO 20085033L NO 20085033 A NO20085033 A NO 20085033A NO 20085033 A NO20085033 A NO 20085033A NO 20085033 L NO20085033 L NO 20085033L
Authority
NO
Norway
Prior art keywords
alkyl
ester
carbocyclic
aryloxy
carboxyl
Prior art date
Application number
NO20085033A
Other languages
English (en)
Inventor
Abraha Habtemariam
Tijana Bugarcic
Peter John Sadler
Original Assignee
Univ Edinburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Edinburgh filed Critical Univ Edinburgh
Publication of NO20085033L publication Critical patent/NO20085033L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00Metallocenes
    • C07F17/02Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

En ruthenium(II) forbindelse av formel (I): eller en solvatform derav for anvendelse i en fremgangsmåte av terapi, hvor: R1, R2, R3, R4, R5 og R6 er uavhengig valgt fra H, C1 -7 alkyl, C5-20 aryl, C3-20 heterosyklyl, halo, ester, amido, acyl, sulfo, sulfonamido, eter, tioeter, azo og amino, eller RI og R2 danner sammen med ringen hvortil de er festet en mettet eller umettet karbosyklisk eller heterosyklisk gruppe inneholdende opp til tre karbosykliske eller heterosykliske ringer med 3 til 8 medlemmer, hvor hver karbosykliske eller heterosykliske ring kan være fusjonert til en eller flere andre karbosykliske eller heterosykliske ringer; * er halo eller en nøytral eller negativt ladet O, N- eller S- donorligand; * er et motion; m er - 1, 0, 1 eller 2; q er 1, 2 eller 3; RC1 og RC2 representerer uavhengig en eller flere eventuelle substituenter valgt fra hydroksyl, C1-7 alkoksy, C5-20 aryloksy, C 1-7 alkyl, karboksyl, C1-7 alkylester og C5-20 arylester; RN1 og RN2 er uavhengig valgt fra hydroksyl, C1-7 alkoksy, C5-20 aryloksy, C1-7 alkyl, karboksyl, C1-7 alkylester og C5-20 arylester; eller RN1 og RN2 danner sammen med pyridinringene hvortil de er bundet en trisyklisk heteroaromatisk halvdel, hvor ringen dannet ved RN1 og RN2 sammen eventuelt kan være substituert ved en eller flere substituenter representert ved RC3 valgt fra: hydroksyl, C1-7 alkoksy, C5-20 aryloksy, C1-7 alkyl, karboksyl, C1-7 alkylester og C5-20 arylester.
NO20085033A 2006-05-19 2008-12-02 Rutenium II forbindelser NO20085033L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0610062.2A GB0610062D0 (en) 2006-05-19 2006-05-19 Ruthenium (ll) compounds
PCT/GB2007/001874 WO2007135410A1 (en) 2006-05-19 2007-05-21 Ruthenium ii compounds

Publications (1)

Publication Number Publication Date
NO20085033L true NO20085033L (no) 2009-02-13

Family

ID=36660553

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20085033A NO20085033L (no) 2006-05-19 2008-12-02 Rutenium II forbindelser

Country Status (13)

Country Link
US (1) US20090186864A1 (no)
EP (1) EP2056801A1 (no)
JP (1) JP2009537503A (no)
KR (1) KR20090024705A (no)
CN (1) CN101489540A (no)
AU (1) AU2007253023A1 (no)
BR (1) BRPI0712715A2 (no)
CA (1) CA2652590A1 (no)
GB (1) GB0610062D0 (no)
MX (1) MX2008014707A (no)
NO (1) NO20085033L (no)
WO (1) WO2007135410A1 (no)
ZA (1) ZA200810499B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2682674C2 (ru) 2013-03-15 2019-03-20 Шерри Энн МАКФАРЛЭНД Координационные комплексы на основе металлов в качестве фотодинамических соединений и их применение
US9751081B2 (en) 2014-12-01 2017-09-05 Clemson University Self-regenerating antioxidant catalysts and methods of using the same
CN108558866A (zh) * 2018-04-11 2018-09-21 苏州科技大学 一种用于制备具有抗肿瘤活性的钌配合物的配体及其制备方法和用途
US10610280B1 (en) 2019-02-02 2020-04-07 Ayad K. M. Agha Surgical method and apparatus for destruction and removal of intraperitoneal, visceral, and subcutaneous fat

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6936624B2 (en) * 1991-04-27 2005-08-30 Nihon Bayer Agrochem K.K. Agents for preserving technical materials against insects
JP2003512471A (ja) * 1999-10-27 2003-04-02 ユニバーシティ コート, エディンバラ大学 窒素および配位子を含む癌治療用の半サンドイッチ状ルテニウム(ii)化合物
GB0016052D0 (en) * 2000-06-30 2000-08-23 Univ Edinburgh Ruthenium (II) compounds
GB0215526D0 (en) * 2002-07-05 2002-08-14 Univ Edinburgh Anticancer compounds
ATE397003T1 (de) * 2003-04-30 2008-06-15 Univ Edinburgh Ruthenium(ii)-komplexe zur behandlung von tumoren
GB0418613D0 (en) * 2004-08-20 2004-09-22 Pugh Rhoderick Internet security system

Also Published As

Publication number Publication date
GB0610062D0 (en) 2006-06-28
AU2007253023A1 (en) 2007-11-29
CN101489540A (zh) 2009-07-22
MX2008014707A (es) 2009-02-04
WO2007135410A1 (en) 2007-11-29
CA2652590A1 (en) 2007-11-29
KR20090024705A (ko) 2009-03-09
BRPI0712715A2 (pt) 2012-05-15
ZA200810499B (en) 2010-01-27
EP2056801A1 (en) 2009-05-13
US20090186864A1 (en) 2009-07-23
JP2009537503A (ja) 2009-10-29

Similar Documents

Publication Publication Date Title
EA201591703A1 (ru) Замещенные 2-азабициклы и их применение в качестве модуляторов рецепторов орексина
CO6290657A2 (es) Derivados polisustituidos de 2-aril-6-fenil-imidazo[1,2-alfa]piridinas su preparacion y su aplicacion en terapeutica
EA201490580A1 (ru) Пирролбензодиазепины и их конъюгаты
AR063800A1 (es) Derivados de acido nicotinico, composiciones farmaceuticas que las contienen y metodos de uso de los mismos
CR11181A (es) Derivados de ftalazinona
RS54638B1 (en) HCV SERIN PROTEASE INHIBITORS DERIVED FROM MACROCYCLIC PROLINE
EA201591429A1 (ru) 2,3-дизамещенные производные 1-ацил-4-амино-1,2,3,4-тетрагидрохинолинов и их применение в качестве ингибиторов бромодомена
AR067613A1 (es) Inhibidores de adn-pk, uso y sintesis de los mismos
NO20085033L (no) Rutenium II forbindelser
EA201591675A1 (ru) Замещенные 7-азабициклы и их применение в качестве модуляторов рецепторов орексина
RS53133B (en) PIRAZOL DERIVATIVES USED AS CCR4 RECEPTOR ANTAGONISTS
AR047890A1 (es) Derivados de azabiciclo[3.1.0]hexano como moduladores de los receptores de dopamina d3
RS54708B1 (en) ARYLETINYL DERIVATIVES
AR081758A1 (es) Compuestos cefem que tienen un grupo catecol, composiciones farmaceuticas que los contienen y su uso en el tratamiento de enfermedades infecciosas
PE20110397A1 (es) Compuestos que modulan selectivamente el receptor cb2
AR102939A1 (es) 3-oxo-3-(arilamino)propanoatos, proceso para prepararlos, y su uso para preparar pirrolidinonas
CY1113812T1 (el) Ετεροκυκλικη ενωση και φαρμακευτικη συνθεση αυτης
EA201171328A1 (ru) Производное замещенного изохинолина
AR070263A1 (es) Derivados de oxazepinopirimidinona arilamido sustituidos, utiles en el tratamiento y/o prevencion de enfermedades neurodegenerativas y otras, medicamentos que los contienen y proceso de preparacion e intermediarios.
NO20071481L (no) Aren-ruthenium (II)-forbindelser og deres anvendelse i kreftterapi
EA200970911A1 (ru) Хинолины и их терапевтическое применение
AR116464A1 (es) Dioxociclobutenilamino-3-hidroxi-picolinamidas n-sustituidas útiles como inhibidores de ccr6
MX2010012303A (es) Agonista de receptor de glucocorticoide compuesto de derivado de 2,2,4-trimetil-6-fenil-1,2-dihidroquinolina que tiene un grupo oxi sustituido.
PE20120637A1 (es) 5-alquinil-piridinas
CN104356110B (zh) 一种硫诱导3,6‑芳香杂环不对称取代‑1,2,4,5‑四嗪化合物及其合成方法

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application