NO20084753L - Fremgangsmate for fremstilling av et taksanderivat - Google Patents

Fremgangsmate for fremstilling av et taksanderivat

Info

Publication number
NO20084753L
NO20084753L NO20084753A NO20084753A NO20084753L NO 20084753 L NO20084753 L NO 20084753L NO 20084753 A NO20084753 A NO 20084753A NO 20084753 A NO20084753 A NO 20084753A NO 20084753 L NO20084753 L NO 20084753L
Authority
NO
Norway
Prior art keywords
preparing
taxane derivative
carbonate
group
isobutylserinyl
Prior art date
Application number
NO20084753A
Other languages
English (en)
Other versions
NO334210B1 (no
Inventor
Daniele Ciceri
Bruno Gabetta
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of NO20084753L publication Critical patent/NO20084753L/no
Publication of NO334210B1 publication Critical patent/NO334210B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Det er beskrevet en forbedret fremgangsmåte for syntese av 13-(N-Boc-ß-isobutylserinyl) 14ß-hydroksybaccatin-III-1,14-karbonat (I) hvor karbonering a 1,14-hyroksygruppene a baccatinstammen utføres med bis(triklormetyl)karbonat og 7-hydroksygruppen blir beskyttet md en trikloracetylgruppe.
NO20084753A 2006-05-12 2008-11-11 Produkter og fremgangsmåte for fremstilling av et taksanderivat NO334210B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06009813A EP1854799B1 (en) 2006-05-12 2006-05-12 Process for the preparation of a taxane derivative
PCT/EP2007/003643 WO2007131601A1 (en) 2006-05-12 2007-04-25 A process for the preparation of a taxane derivative

Publications (2)

Publication Number Publication Date
NO20084753L true NO20084753L (no) 2008-11-11
NO334210B1 NO334210B1 (no) 2014-01-13

Family

ID=37708167

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084753A NO334210B1 (no) 2006-05-12 2008-11-11 Produkter og fremgangsmåte for fremstilling av et taksanderivat

Country Status (20)

Country Link
EP (1) EP1854799B1 (no)
JP (1) JP5154546B2 (no)
KR (1) KR101402122B1 (no)
CN (1) CN101448839B (no)
AR (1) AR061088A1 (no)
AT (1) ATE507231T1 (no)
BR (1) BRPI0711805B8 (no)
CA (1) CA2652008C (no)
DE (1) DE602006021546D1 (no)
DK (1) DK1854799T3 (no)
ES (1) ES2363524T3 (no)
HK (1) HK1111985A1 (no)
IL (1) IL195220A (no)
MX (1) MX2008014447A (no)
NO (1) NO334210B1 (no)
PE (1) PE20080398A1 (no)
RU (1) RU2434014C2 (no)
UY (1) UY30341A1 (no)
WO (1) WO2007131601A1 (no)
ZA (1) ZA200809613B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2080764B1 (en) 2008-01-18 2012-08-22 INDENA S.p.A. Solid forms of ortataxel
CN105985353B (zh) 2015-02-11 2020-07-21 中国科学院上海药物研究所 一种化合物的a晶型及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3269190D1 (en) * 1982-09-03 1986-03-27 Wieland Werke Ag Finned tube with internal projections and method and apparatus for its manufacture
DE3440141A1 (de) * 1984-11-02 1986-05-07 Heiner Dipl.-Chem. Dr. 8000 München Eckert Verwendung von kohlensaeure-bis-trichlormethylester als proreagens fuer phosgen
KR100225535B1 (ko) * 1996-08-27 1999-10-15 정지석 파클리탁셀의 제조방법
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
IT1319682B1 (it) * 2000-12-06 2003-10-23 Indena Spa Procedimento di sintesi del paclitaxel.

Also Published As

Publication number Publication date
HK1111985A1 (en) 2008-08-22
RU2008144391A (ru) 2010-05-20
EP1854799B1 (en) 2011-04-27
NO334210B1 (no) 2014-01-13
BRPI0711805A2 (pt) 2011-12-06
KR101402122B1 (ko) 2014-05-30
PE20080398A1 (es) 2008-05-26
CA2652008A1 (en) 2007-11-22
WO2007131601A1 (en) 2007-11-22
UY30341A1 (es) 2007-11-30
KR20090015923A (ko) 2009-02-12
ZA200809613B (en) 2010-02-24
ATE507231T1 (de) 2011-05-15
IL195220A0 (en) 2009-08-03
BRPI0711805B1 (pt) 2020-09-24
CN101448839B (zh) 2011-09-21
ES2363524T3 (es) 2011-08-08
CN101448839A (zh) 2009-06-03
EP1854799A1 (en) 2007-11-14
BRPI0711805B8 (pt) 2021-05-25
CA2652008C (en) 2014-12-30
JP5154546B2 (ja) 2013-02-27
DK1854799T3 (da) 2011-07-18
DE602006021546D1 (de) 2011-06-09
MX2008014447A (es) 2008-11-26
AR061088A1 (es) 2008-08-06
JP2009536928A (ja) 2009-10-22
RU2434014C2 (ru) 2011-11-20
IL195220A (en) 2014-03-31

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