NO20082875L - Fremgangsmate for produksjon av forbindelse merket med radioaktivt fluor - Google Patents
Fremgangsmate for produksjon av forbindelse merket med radioaktivt fluorInfo
- Publication number
- NO20082875L NO20082875L NO20082875A NO20082875A NO20082875L NO 20082875 L NO20082875 L NO 20082875L NO 20082875 A NO20082875 A NO 20082875A NO 20082875 A NO20082875 A NO 20082875A NO 20082875 L NO20082875 L NO 20082875L
- Authority
- NO
- Norway
- Prior art keywords
- preparing
- radioactive fluorine
- compound labeled
- producing compound
- tafdg
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B61/00—Other general methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Optics & Photonics (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Det beskrives en fremgangsmåte for fremstilling av l8F-TAFDG som kan gi 18F-TAFDG i et høyt radiofluoreringsutbytte. En fremgangsmåte for fremstilling av en organisk forbindelse merket med radioaktivt fluor omfatter trinnene: fremstilling av en reaksjonsoppløsning inneholdende [18F]fluoridioner, en faseoverføringskatalysator, kaliumioner, l,3,4,6-tetra-0-acetyl-2-0-trifluorometansulfonyl-(3-D-mannopyranose som en merkingsforløperforbindelse og et oppløsningsmiddel; og å tilveiebringe en reaksjonsbetingelse for reaksjonsoppløsningen for å oppnå l,3,4,6-tetra-0-acetyl-2-[18F]fluoro-2-deoksyglukose, der oppløsningsmidlet inneholder vann.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005352464 | 2005-12-06 | ||
PCT/JP2006/323933 WO2007066567A1 (ja) | 2005-12-06 | 2006-11-30 | 放射性フッ素標識有機化合物の製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20082875L true NO20082875L (no) | 2008-08-28 |
Family
ID=38122713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082875A NO20082875L (no) | 2005-12-06 | 2008-06-24 | Fremgangsmate for produksjon av forbindelse merket med radioaktivt fluor |
Country Status (9)
Country | Link |
---|---|
US (1) | US20090281294A1 (no) |
EP (1) | EP1958954A4 (no) |
JP (1) | JP5106118B2 (no) |
KR (1) | KR20080074145A (no) |
CN (1) | CN101346392A (no) |
AU (1) | AU2006322673A1 (no) |
CA (1) | CA2632133A1 (no) |
NO (1) | NO20082875L (no) |
WO (1) | WO2007066567A1 (no) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008029734A1 (fr) * | 2006-09-06 | 2008-03-13 | Nihon Medi-Physics Co., Ltd. | Procédé de fabrication d'un composé organique marqué au fluor radioactif, et appareil et programme de synthèse correspondants |
KR101430422B1 (ko) * | 2010-04-08 | 2014-08-14 | 지멘스 메디컬 솔루션즈 유에스에이, 인크. | 함수 유기 용매에서 18f-표지된 트레이서의 합성 |
WO2016084193A1 (ja) * | 2014-11-27 | 2016-06-02 | 国立大学法人東京工業大学 | 6-デオキシ-6-放射性ヨード-d-グルコースの製造方法、及びその方法に用いる高分子化合物 |
AU2020309307B2 (en) * | 2019-07-09 | 2023-03-30 | F. Hoffmann-La Roche Ag | Process for the deprotection of oligonucleotides |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2738224B2 (ja) | 1992-06-15 | 1998-04-08 | 日本鋼管株式会社 | 18f標識有機化合物の製造法 |
US5264570A (en) * | 1992-08-05 | 1993-11-23 | General Electric Company | Method for making 2-[18 F]fluoro-2-deoxy-D-glucose |
BE1010280A3 (fr) | 1996-05-02 | 1998-05-05 | Coincidence S A | Procede et dispositif de synthese de 2-[18f] fluoro-2-deoxy-d-glucose. |
JP4979945B2 (ja) * | 2003-09-30 | 2012-07-18 | 日本メジフィジックス株式会社 | 放射性フッ素化合物の製造方法 |
GB0425501D0 (en) * | 2004-11-19 | 2004-12-22 | Amersham Plc | Fluoridation process |
-
2006
- 2006-11-30 CA CA002632133A patent/CA2632133A1/en not_active Abandoned
- 2006-11-30 WO PCT/JP2006/323933 patent/WO2007066567A1/ja active Application Filing
- 2006-11-30 JP JP2007549091A patent/JP5106118B2/ja not_active Expired - Fee Related
- 2006-11-30 CN CNA2006800489878A patent/CN101346392A/zh active Pending
- 2006-11-30 EP EP06833736A patent/EP1958954A4/en not_active Withdrawn
- 2006-11-30 AU AU2006322673A patent/AU2006322673A1/en not_active Abandoned
- 2006-11-30 KR KR1020087013012A patent/KR20080074145A/ko not_active Application Discontinuation
- 2006-11-30 US US12/086,147 patent/US20090281294A1/en not_active Abandoned
-
2008
- 2008-06-24 NO NO20082875A patent/NO20082875L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20090281294A1 (en) | 2009-11-12 |
EP1958954A4 (en) | 2009-12-30 |
CA2632133A1 (en) | 2007-06-14 |
CN101346392A (zh) | 2009-01-14 |
JP5106118B2 (ja) | 2012-12-26 |
KR20080074145A (ko) | 2008-08-12 |
EP1958954A1 (en) | 2008-08-20 |
JPWO2007066567A1 (ja) | 2009-05-14 |
AU2006322673A1 (en) | 2007-06-14 |
WO2007066567A1 (ja) | 2007-06-14 |
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Legal Events
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