NO20082125L - Substituerte benzokondenserte derivater og deres anvendelse som vanilloidreseptorligander - Google Patents
Substituerte benzokondenserte derivater og deres anvendelse som vanilloidreseptorliganderInfo
- Publication number
- NO20082125L NO20082125L NO20082125A NO20082125A NO20082125L NO 20082125 L NO20082125 L NO 20082125L NO 20082125 A NO20082125 A NO 20082125A NO 20082125 A NO20082125 A NO 20082125A NO 20082125 L NO20082125 L NO 20082125L
- Authority
- NO
- Norway
- Prior art keywords
- receptor ligands
- substituted benzo
- fused derivatives
- vanilloid receptor
- methods
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 2
- 102000011040 TRPV Cation Channels Human genes 0.000 title 1
- 108010062740 TRPV Cation Channels Proteins 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
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Abstract
Foreliggende oppfinnelse angår substituerte benzosammensmeltede derivater, som kan anvendes som vaniloidreseptorligander, fremgangsmåter for behandling av sykdommer, tilstander og/eller forstyrrelser modulert av vaniloidreseptorer og fremgangsmåter for fremstilling av dem.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1269MU2005 | 2005-10-07 | ||
US73066005P | 2005-10-26 | 2005-10-26 | |
IN996MU2006 | 2006-06-26 | ||
US80720506P | 2006-07-13 | 2006-07-13 | |
PCT/IB2006/002814 WO2007042906A1 (en) | 2005-10-07 | 2006-10-09 | Substituted benzofused derivatives and their use as vanilloid receptor ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20082125L true NO20082125L (no) | 2008-07-07 |
Family
ID=37603267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082125A NO20082125L (no) | 2005-10-07 | 2008-05-06 | Substituerte benzokondenserte derivater og deres anvendelse som vanilloidreseptorligander |
Country Status (12)
Country | Link |
---|---|
US (4) | US7842703B2 (no) |
EP (1) | EP1931681B1 (no) |
JP (1) | JP2009511465A (no) |
KR (1) | KR20080064972A (no) |
AP (1) | AP2008004432A0 (no) |
AR (1) | AR057543A1 (no) |
CA (1) | CA2624307C (no) |
EA (1) | EA200801013A1 (no) |
IL (1) | IL190587A0 (no) |
NO (1) | NO20082125L (no) |
TW (1) | TW200801013A (no) |
WO (1) | WO2007042906A1 (no) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA200801013A1 (ru) * | 2005-10-07 | 2008-10-30 | Гленмарк Фармасеутикалс С.А. | Производные замещённых соединений, содержащих конденсированные бензольные кольца, и их применение в качестве лигандов ванилоидных рецепторов |
KR20080111144A (ko) | 2006-04-18 | 2008-12-22 | 아보트 러보러터리즈 | 바닐로이드 수용체 서브타입 1(vr1)의 길항제 및 이의 용도 |
EP2032585B1 (de) | 2006-05-24 | 2014-07-23 | Boehringer Ingelheim International GmbH | Substituierte pteridine als therapeutika |
WO2008110863A1 (en) * | 2007-03-15 | 2008-09-18 | Glenmark Pharmaceuticals S.A. | Indazole derivatives and their use as vanilloid receptor ligands |
CA2702455A1 (en) * | 2007-10-16 | 2009-04-23 | Santen Pharmaceutical Co., Ltd. | Therapeutic agent for trpv1-mediated disease |
US8487121B2 (en) | 2007-12-18 | 2013-07-16 | Glenmark Pharmaceuticals S.A. | Chromane derivatives as TRPV3 modulators |
WO2009081219A1 (en) * | 2007-12-20 | 2009-07-02 | Glenmark Pharmaceuticals, S.A. | Quinazoline derivatives as vanilloid receptor modulators |
EA018133B1 (ru) * | 2008-01-11 | 2013-05-30 | Гленмарк Фармасьютикалс, С.А. | Конденсированные пиримидиновые производные как модуляторы trpv3 |
JP5643112B2 (ja) | 2008-01-28 | 2014-12-17 | アモーレパシフィック コーポレイションAmorepacific Corporation | バニロイド受容体としての新規化合物、その異性体または薬剤学的に許容し得る塩、及びこれを含有する医薬組成物 |
WO2009095726A1 (en) * | 2008-01-29 | 2009-08-06 | Glenmark Pharmaceuticals, S.A. | Acrylamide derivatives as vanilloid receptor 1 modulators |
NZ595780A (en) | 2008-06-17 | 2013-07-26 | Glenmark Pharmaceuticals Sa | Chromane derivatives as trpv3 modulators |
CN102137851B (zh) | 2008-07-02 | 2014-08-27 | 株式会社爱茉莉太平洋 | 作为香草素受体拮抗剂的化合物、其异构体或其药学可接受的盐以及包含它们的药物组合物 |
WO2010023512A1 (en) * | 2008-08-28 | 2010-03-04 | Matrix Laboratories Ltd. | Novel vanilloid receptor modulators, process for their preparation and pharmaceutical compositions containing them |
JP2012505908A (ja) * | 2008-10-17 | 2012-03-08 | アボット・ラボラトリーズ | Trpv1アンタゴニスト |
US8604053B2 (en) | 2008-10-17 | 2013-12-10 | Abbvie Inc. | TRPV1 antagonists |
US8318928B2 (en) | 2008-12-15 | 2012-11-27 | Glenmark Pharmaceuticals, S.A. | Fused imidazole carboxamides as TRPV3 modulators |
GEP20146096B (en) | 2008-12-26 | 2014-05-27 | Glenmark Pharmaceuticals Sa | Fused imidazole derivatives as trpv3 antagonists |
US8349852B2 (en) | 2009-01-13 | 2013-01-08 | Novartis Ag | Quinazolinone derivatives useful as vanilloid antagonists |
WO2011092293A2 (en) | 2010-02-01 | 2011-08-04 | Novartis Ag | Cyclohexyl amide derivatives as crf receptor antagonists |
US20120295942A1 (en) | 2010-02-01 | 2012-11-22 | Nicholas James Devereux | Pyrazolo[5,1b]oxazole Derivatives as CRF-1 Receptor Antagonists |
JP5748777B2 (ja) | 2010-02-02 | 2015-07-15 | ノバルティス アーゲー | Crf受容体アンタゴニストとしてのシクロヘキシルアミド誘導体 |
WO2012049555A1 (en) | 2010-10-13 | 2012-04-19 | Lupin Limited | Spirocyclic compounds as voltage-gated sodium channel modulators |
EP2635281B1 (en) * | 2010-11-03 | 2018-03-14 | University Of Hawaii | Methods and compositions for prevention and treatment of cardiac hypertrophy |
TW201302681A (zh) | 2011-03-25 | 2013-01-16 | Abbott Lab | Trpv1拮抗劑 |
US8969325B2 (en) | 2011-12-19 | 2015-03-03 | Abbvie Inc. | TRPV1 antagonists |
US8859584B2 (en) | 2011-12-19 | 2014-10-14 | Abbvie, Inc. | TRPV1 antagonists |
US8796328B2 (en) | 2012-06-20 | 2014-08-05 | Abbvie Inc. | TRPV1 antagonists |
EP3010586A1 (en) | 2013-06-21 | 2016-04-27 | Lupin Limited | Substituted heterocyclic compounds as crac modulators |
CA2914415A1 (en) | 2013-06-24 | 2014-12-31 | Lupin Limited | Chromane and chromene derivatives and their use as crac modulators |
GB201401886D0 (en) | 2014-02-04 | 2014-03-19 | Lytix Biopharma As | Neurodegenerative therapies |
EP3484528B1 (en) | 2016-07-18 | 2020-11-25 | Janssen Pharmaceutica NV | Tau pet imaging ligands |
RU2755206C1 (ru) | 2020-05-20 | 2021-09-14 | Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) | Средство пролонгированного анальгетического действия и лекарственный препарат на его основе |
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FR2661676A1 (fr) | 1990-05-02 | 1991-11-08 | Lipha | Derives d'amino benzocycloalcanes, procedes de preparation et medicaments les contenant. |
AU651105B2 (en) | 1990-06-18 | 1994-07-14 | E.R. Squibb & Sons, Inc. | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents |
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US5869478A (en) | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
DE19808861A1 (de) | 1997-04-09 | 1999-09-16 | H G L Consulting Und Projektma | Verfahren und Vorrichtung zur Reinigung einer WC-Schüssel |
WO2000003681A2 (en) * | 1998-07-16 | 2000-01-27 | Axys Pharmaceuticals, Inc. | Process for the synthesis of benzopyran derivatives |
IL153884A0 (en) | 2000-07-20 | 2003-07-31 | Neurogen Corp | Capsaicin receptor ligands |
US20030153596A1 (en) | 2000-08-21 | 2003-08-14 | Suh Young Ger | Novel thiourea derivatives and the pharmaceutical compositions containing the same |
WO2002016318A1 (en) | 2000-08-21 | 2002-02-28 | Pacific Corporation | Novel thiourea derivatives and the pharmaceutical compositions containing the same |
AU2001278821A1 (en) | 2000-08-21 | 2002-03-04 | Pacific Corporation | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same |
GB0110901D0 (en) | 2001-05-02 | 2001-06-27 | Smithkline Beecham Plc | Novel Compounds |
GB0206876D0 (en) * | 2002-03-22 | 2002-05-01 | Merck Sharp & Dohme | Therapeutic agents |
KR100556158B1 (ko) | 2002-10-17 | 2006-03-06 | (주) 디지탈바이오텍 | 신규 엔-하이드록시 티오우레아, 우레아 및 아미드계화합물 및 이를 함유하는 약제학적 조성물 |
US6933311B2 (en) | 2003-02-11 | 2005-08-23 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
WO2004103281A2 (en) | 2003-05-16 | 2004-12-02 | Georgetown University | Vanilloid receptor antagonists, and methods of making and using them |
WO2004108133A2 (en) | 2003-06-05 | 2004-12-16 | Vertex Pharmaceuticals Incorporated | Modulators of vr1 receptor |
PT2017265E (pt) | 2003-06-12 | 2011-07-29 | Abbott Lab | Compostos condensados que inibem o receptor vanilóide de subtipo 1 (vr1) |
TW200510373A (en) | 2003-07-14 | 2005-03-16 | Neurogen Corp | Substituted quinolin-4-ylamine analogues |
AU2004259712A1 (en) | 2003-07-15 | 2005-02-03 | Neurogen Corporation | Substituted pyrimidin-4-ylamine analogues |
EP1589015A1 (en) * | 2004-02-03 | 2005-10-26 | Université de Liège | Benzopyran derivatives, method of production and use thereof |
EA200801013A1 (ru) * | 2005-10-07 | 2008-10-30 | Гленмарк Фармасеутикалс С.А. | Производные замещённых соединений, содержащих конденсированные бензольные кольца, и их применение в качестве лигандов ванилоидных рецепторов |
KR20080111144A (ko) * | 2006-04-18 | 2008-12-22 | 아보트 러보러터리즈 | 바닐로이드 수용체 서브타입 1(vr1)의 길항제 및 이의 용도 |
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2006
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- 2006-10-09 AP AP2008004432A patent/AP2008004432A0/xx unknown
- 2006-10-09 AR ARP060104442A patent/AR057543A1/es unknown
- 2006-10-09 KR KR1020087011019A patent/KR20080064972A/ko not_active Application Discontinuation
- 2006-10-09 EP EP06808980A patent/EP1931681B1/en active Active
- 2006-10-09 US US12/067,879 patent/US7842703B2/en not_active Expired - Fee Related
- 2006-10-09 JP JP2008534106A patent/JP2009511465A/ja active Pending
- 2006-10-09 WO PCT/IB2006/002814 patent/WO2007042906A1/en active Application Filing
- 2006-10-09 CA CA2624307A patent/CA2624307C/en not_active Expired - Fee Related
- 2006-10-11 TW TW095137319A patent/TW200801013A/zh unknown
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2008
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TW200801013A (en) | 2008-01-01 |
KR20080064972A (ko) | 2008-07-10 |
US20080269253A1 (en) | 2008-10-30 |
IL190587A0 (en) | 2008-11-03 |
US20120277259A1 (en) | 2012-11-01 |
JP2009511465A (ja) | 2009-03-19 |
WO2007042906A1 (en) | 2007-04-19 |
US20110021549A1 (en) | 2011-01-27 |
AP2008004432A0 (en) | 2008-04-30 |
CA2624307A1 (en) | 2007-04-19 |
AR057543A1 (es) | 2007-12-05 |
US20120041011A1 (en) | 2012-02-16 |
AU2006300871A1 (en) | 2007-04-19 |
CA2624307C (en) | 2014-04-29 |
EP1931681A1 (en) | 2008-06-18 |
EP1931681B1 (en) | 2012-11-14 |
US7842703B2 (en) | 2010-11-30 |
EA200801013A1 (ru) | 2008-10-30 |
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