NO20076465L - PIGG YBAC som et verktoy for genetisk manipulasjon og analyser i vertebrater - Google Patents

PIGG YBAC som et verktoy for genetisk manipulasjon og analyser i vertebrater

Info

Publication number
NO20076465L
NO20076465L NO20076465A NO20076465A NO20076465L NO 20076465 L NO20076465 L NO 20076465L NO 20076465 A NO20076465 A NO 20076465A NO 20076465 A NO20076465 A NO 20076465A NO 20076465 L NO20076465 L NO 20076465L
Authority
NO
Norway
Prior art keywords
vertebrates
ybac
pigg
tool
analysis
Prior art date
Application number
NO20076465A
Other languages
English (en)
Norwegian (no)
Inventor
Tian Xu
Min Han
Yuan Zhuang
Xiaohui Wu
Sheng Ding
Gang Li
Original Assignee
Univ Fudan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Fudan filed Critical Univ Fudan
Publication of NO20076465L publication Critical patent/NO20076465L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO20076465A 2005-05-14 2007-12-14 PIGG YBAC som et verktoy for genetisk manipulasjon og analyser i vertebrater NO20076465L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2005/000674 WO2006122442A1 (en) 2005-05-14 2005-05-14 Piggybac as a tool for genetic manipulation and analysis in vertebrates

Publications (1)

Publication Number Publication Date
NO20076465L true NO20076465L (no) 2008-02-04

Family

ID=37430916

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076465A NO20076465L (no) 2005-05-14 2007-12-14 PIGG YBAC som et verktoy for genetisk manipulasjon og analyser i vertebrater

Country Status (11)

Country Link
US (1) US20100154070A1 (pt)
EP (1) EP1896578A4 (pt)
JP (1) JP2008545375A (pt)
CN (1) CN101297031B (pt)
AU (1) AU2005331864A1 (pt)
BR (1) BRPI0520212A2 (pt)
CA (1) CA2608481A1 (pt)
IL (1) IL187348A0 (pt)
MX (1) MX2007014139A (pt)
NO (1) NO20076465L (pt)
WO (1) WO2006122442A1 (pt)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10087463B2 (en) * 2000-10-31 2018-10-02 University Of Notre Dame Du Lac Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac
WO2008027384A1 (en) * 2006-08-28 2008-03-06 University Of Hawaii Methods and compositions for transposon-mediated transgenesis
WO2008098181A2 (en) 2007-02-09 2008-08-14 University Of Utah Research Foundation In vivo genome-wide mutagenesis
US20090042297A1 (en) * 2007-06-01 2009-02-12 George Jr Alfred L Piggybac transposon-based vectors and methods of nucleic acid integration
EP3255144A1 (en) 2007-08-10 2017-12-13 E. R. Squibb & Sons, L.L.C. Recombineering construct for preparing transgenic mice capable of producing human immunoglobulin
EP3184632B1 (en) 2009-02-26 2024-04-03 Poseida Therapeutics, Inc. Hyperactive piggybac transposases
DK3028565T3 (da) 2009-07-08 2017-11-13 Kymab Ltd Dyremodeller og terapeutiske molekyler
US9445581B2 (en) 2012-03-28 2016-09-20 Kymab Limited Animal models and therapeutic molecules
CN101851637B (zh) * 2010-01-15 2011-12-14 中国农业科学院北京畜牧兽医研究所 一种制备同时表达多个基因的转基因动物的方法
US20130045492A1 (en) 2010-02-08 2013-02-21 Regeneron Pharmaceuticals, Inc. Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
US9796788B2 (en) 2010-02-08 2017-10-24 Regeneron Pharmaceuticals, Inc. Mice expressing a limited immunoglobulin light chain repertoire
MX2012009168A (es) 2010-02-08 2012-08-31 Regeneron Pharma Raton de cadena ligera comun.
HRP20241480T1 (hr) 2011-08-05 2025-01-03 Regeneron Pharmaceuticals, Inc. Humanizirani miševi univerzalnog lakog lanca
CN103945689B (zh) 2011-09-19 2016-10-19 科马布有限公司 免疫球蛋白基因多样性的操纵及多抗体治疗剂
EP2761008A1 (en) 2011-09-26 2014-08-06 Kymab Limited Chimaeric surrogate light chains (slc) comprising human vpreb
US9253965B2 (en) 2012-03-28 2016-02-09 Kymab Limited Animal models and therapeutic molecules
US10251377B2 (en) 2012-03-28 2019-04-09 Kymab Limited Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies
GB2502127A (en) 2012-05-17 2013-11-20 Kymab Ltd Multivalent antibodies and in vivo methods for their production
CN102943092B (zh) * 2012-11-20 2014-12-10 西北农林科技大学 一种通用型PiggyBac转座子转基因载体及其制备方法
US9788534B2 (en) 2013-03-18 2017-10-17 Kymab Limited Animal models and therapeutic molecules
US9783618B2 (en) 2013-05-01 2017-10-10 Kymab Limited Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics
US11707056B2 (en) 2013-05-02 2023-07-25 Kymab Limited Animals, repertoires and methods
US9783593B2 (en) 2013-05-02 2017-10-10 Kymab Limited Antibodies, variable domains and chains tailored for human use
WO2014196931A1 (en) * 2013-06-06 2014-12-11 Agency For Science, Technology And Research A transposon for genome manipulation
US9840718B2 (en) 2013-07-12 2017-12-12 University Of South Alabama Minimal piggyBac vectors for genome integration
SG11201602236SA (en) 2013-10-01 2016-04-28 Kymab Ltd Animal models and therapeutic molecules
EP3071689A1 (en) 2013-11-18 2016-09-28 Yale University Compositions and methods of using transposons
EP3094729A1 (en) * 2014-01-14 2016-11-23 Lam Therapeutics, Inc. Mutagenesis methods
RU2016141307A (ru) 2014-03-21 2018-04-24 Регенерон Фармасьютикалз, Инк. Отличные от человека животные, которые вырабатывают однодоменные связывающие белки
LT3129487T (lt) * 2014-04-09 2020-12-28 Dna Twopointo Inc. Patobulinti nukleorūgščių konstruktai, skirti eukariotinio geno raiškai
US10041077B2 (en) 2014-04-09 2018-08-07 Dna2.0, Inc. DNA vectors, transposons and transposases for eukaryotic genome modification
HK1250038A1 (zh) 2015-03-19 2018-11-23 瑞泽恩制药公司 选择结合抗原的轻链可变区的非人动物
CN106521638A (zh) * 2015-09-09 2017-03-22 潘雨堃 一种基因突变大鼠资源库及其制备方法
CN106544359B (zh) * 2015-09-22 2019-07-19 复旦大学 Gpr45基因的用途
EP3359671B1 (en) 2015-10-08 2021-08-18 Dna Twopointo Inc. Dna vectors, transposons and transposases for eukaryotic genome modification
CN108474005B (zh) * 2015-12-14 2022-10-21 先驱生技股份有限公司 转位子系统、试剂盒及其用途
CN108779469A (zh) * 2016-03-25 2018-11-09 基因体先驱生医股份有限公司 用以建构转位子的套组及其用途
FI3556855T3 (fi) * 2016-12-14 2026-03-25 Shinshu Univ Kimeerisen antigeenireseptorin geenimuunneltu lymfosyytti, jolla on sytosidinen vaikutus
JP7203367B2 (ja) * 2017-12-14 2023-01-16 公益財団法人実験動物中央研究所 哺乳動物細胞用遺伝子導入ベクター
WO2019219947A1 (en) * 2018-05-18 2019-11-21 Sorbonne Universite Molecular tools and methods for transgene integration and their transposition dependent expression
KR20210049859A (ko) 2018-08-28 2021-05-06 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 게놈을 조절하는 방법 및 조성물
CN113348248B (zh) 2018-10-24 2024-12-31 思兰克斯有限公司 表达系统、重组细胞及其用途
MY206450A (en) * 2019-04-08 2024-12-17 Dna Twopointo Inc Transposition of nucleic acid constructs into eukaryotic genomes with a transposase from amyelois
AU2020272668B2 (en) * 2019-04-08 2023-07-06 Dna Twopointo Inc. Integration of nucleic acid constructs into eukaryotic cells with a transposase from oryzias
CN111909986B (zh) * 2019-05-10 2024-03-26 潘雨堃 一种基因治疗安全评估与毒副作用预防的方法
JP7769325B2 (ja) 2019-07-23 2025-11-13 株式会社東芝 Ｃａｒ－ｔ細胞の製造方法、核酸導入キャリア及びキット
JP7630904B2 (ja) * 2019-07-23 2025-02-18 株式会社東芝 核酸導入キャリア、核酸導入キャリアセット、核酸導入組成物及び核酸導入方法
WO2021164704A2 (en) * 2020-02-19 2021-08-26 Wuxi Biologics (Shanghai) Co., Ltd. Enhanced expression system and methods of use thereof
CN113584083A (zh) 2020-04-30 2021-11-02 深圳市深研生物科技有限公司 用于逆转录病毒载体的生产细胞和包装细胞及其制备方法
CN111534542A (zh) * 2020-05-07 2020-08-14 西南大学 piggyBac转座子系统介导的真核生物转基因细胞系及构建方法
CN113930446B (zh) * 2020-07-13 2024-06-28 未来模式(苏州)生物科技有限公司 对非人动物基因改造的方法及构建的免疫缺陷动物模型
IL311333A (en) 2021-09-09 2024-05-01 Iovance Biotherapeutics Inc Processes for generating til products using pd-1 talen knockdown
CA3243419A1 (en) 2022-01-28 2023-08-03 Iovance Biotherapeutics, Inc. CYTOKINE-ASSOCIATED TUMOR-INFILTRATING LYMPHOCYTE COMPOSITIONS AND PROCESSES
WO2024112571A2 (en) 2022-11-21 2024-05-30 Iovance Biotherapeutics, Inc. Two-dimensional processes for the expansion of tumor infiltrating lymphocytes and therapies therefrom
WO2024118836A1 (en) 2022-11-30 2024-06-06 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes with shortened rep step
WO2024168311A2 (en) * 2023-02-09 2024-08-15 The Brigham And Women’S Hospital, Inc. Autonomous gene circuits for therapy release
WO2025101484A1 (en) 2023-11-06 2025-05-15 Iovance Biotherapeutics, Inc. Treatment of endometrial cancers with tumor infiltrating lymphocyte therapies
CN118879694A (zh) * 2024-06-12 2024-11-01 扬州大学 一种Buster转座子系统及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218185B1 (en) * 1996-04-19 2001-04-17 The United States Of America As Represented By The Secretary Of Agriculture Piggybac transposon-based genetic transformation system for insects
US20030150007A1 (en) * 2000-03-21 2003-08-07 Charalambos Savakis Method of generating transgenic organisms using transposons
US6962810B2 (en) * 2000-10-31 2005-11-08 University Of Notre Dame Du Lac Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac
DK1465993T3 (da) * 2002-01-09 2010-01-11 Minos Biosystems Ltd Inducerbar transposition hos transgen organisme ved anvendelse af transposonvektor
CN1234871C (zh) * 2003-03-27 2006-01-04 成都天创生物科技有限责任公司 一种解毒酶基因在家蚕中稳定表达系统的构建方法

Also Published As

Publication number Publication date
CN101297031A (zh) 2008-10-29
JP2008545375A (ja) 2008-12-18
EP1896578A4 (en) 2008-11-05
BRPI0520212A2 (pt) 2009-08-18
EP1896578A1 (en) 2008-03-12
CN101297031B (zh) 2013-06-05
CA2608481A1 (en) 2006-11-23
US20100154070A1 (en) 2010-06-17
AU2005331864A1 (en) 2006-11-23
IL187348A0 (en) 2008-04-13
MX2007014139A (es) 2008-10-09
WO2006122442A1 (en) 2006-11-23

Similar Documents

Publication Publication Date Title
NO20076465L (no) PIGG YBAC som et verktoy for genetisk manipulasjon og analyser i vertebrater
Xiang et al. The evolutionary road from wild moth to domestic silkworm
Palaiokostas et al. Accuracy of genomic evaluations of juvenile growth rate in common carp (Cyprinus carpio) using genotyping by sequencing
Bewick et al. Dnmt1 is essential for egg production and embryo viability in the large milkweed bug, Oncopeltus fasciatus
Wells et al. Genome‐editing technologies to improve research, reproduction, and production in pigs
NO20076024L (no) Anti-IL-6 antistoffer, sammensetninger, fremgangsmater og anvendelser
EA200701426A1 (ru) Композиция клещей, её применение, способ разведения хищного клеща - фитосейида amblyseius swirskii, система для разведения указанного хищного клеща и способы биологического контроля вредителей в культуре
Xia et al. Whole genome scanning and association mapping identified a significant association between growth and a SNP in the IFABP-a gene of the Asian seabass
Sandrin et al. Multiple paternity and mating group size in the E uropean earwig, F orficula auricularia
DK1049372T3 (da) Full-term udvikling af dyr fra enukleerede oocyter rekonstitueret med adulte somatiske cellekerner
BRPI0816880A2 (pt) métodos para produzir uma planta com rendimento aumentado em comparação com uma planta do tipo selvagem correspondente, para produzir uma planta transgênica com rendimento aumentado em comparação com uma planta do tipo selvagem não transformada correspondente, para produzir uma composição agrícola, para identificar uma planta com um rendimento aumentado, e para aumentar o rendimento de uma população de plantas, molécula de ácido nucleico isolada, construção de ácido nucléico, vetor, processos para produzir um polipeptídeo, e para identificar um composto, polipeptídeo, anticorpo, núcleo de célula de planta, célula de planta, tecido de planta, material de propagação, pólen, progênie, material colhido ou planta, semente, parte de planta, planta transgênica, planta transgênica, núcleo de célula de planta transgênica, célula de planta transgênica, planta que compreende um ou mais de tais núcleos de célula de planta transgênica ou células de planta, progênie, semente ou pólen derivado de ou produzido por uma planta transgênica, composição, e, uso dos ácidos nucleicos.
EA200701427A1 (ru) Композиция клещей, её применение, способ разведения хищного клеща - фитосейида, система для разведения указанного хищного клеща - фитосейида и способы биологического контроля вредителей в культуре
EP1534066A4 (en) CELLS WITHOUT ALPHA (1,3) -GALACTOSYLTRANSFERASE, METHODS OF SELECTION, AND PORK HAVING ALPHA (1,3) -GALACTOSYLTRANSFERASE THUS OBTAINED
Higuchi et al. Targeted mutagenesis of the ryanodine receptor by Platinum TALENs causes slow swimming behaviour in Pacific bluefin tuna (Thunnus orientalis)
DK1954811T3 (da) Inducerbare ekspressionssystemer
Silva et al. Development and validation of a low-density SNP panel for paternity and kinship analysis and evaluation of genetic variability and structure of commercial Pacific white shrimp (Litopenaeus vannamei) populations from Brazil
NO20074027L (no) DNA markorer for oket melkeproduksjon i storfe
NO20074061L (no) DNA markorer for storfevekst
JP2005538685A5 (pt)
Castellanos et al. The roles of gene duplications in the dynamics of evolutionary conflicts
Wang et al. Mitochondrial complex I deficiency leads to the retardation of early embryonic development in Ndufs4 knockout mice
Brandies et al. Disentangling the mechanisms of mate choice in a captive koala population
CY1112746T1 (el) Κρυοσυντηρηση ηπατοκυτταρων
Feldmeyer et al. Comparative evolutionary genomics in insects
Peng et al. NADPH oxidase 5 is essential for molting and oviposition in a rice planthopper Nilaparvata lugens

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application