DK1049372T3 - Full-term udvikling af dyr fra enukleerede oocyter rekonstitueret med adulte somatiske cellekerner - Google Patents
Full-term udvikling af dyr fra enukleerede oocyter rekonstitueret med adulte somatiske cellekernerInfo
- Publication number
- DK1049372T3 DK1049372T3 DK99902382T DK99902382T DK1049372T3 DK 1049372 T3 DK1049372 T3 DK 1049372T3 DK 99902382 T DK99902382 T DK 99902382T DK 99902382 T DK99902382 T DK 99902382T DK 1049372 T3 DK1049372 T3 DK 1049372T3
- Authority
- DK
- Denmark
- Prior art keywords
- adult somatic
- animals
- cell nuclei
- somatic cell
- nucleus
- Prior art date
Links
- 210000004940 nucleus Anatomy 0.000 title abstract 5
- 210000000287 oocyte Anatomy 0.000 title abstract 5
- 241001465754 Metazoa Species 0.000 title abstract 3
- 210000001082 somatic cell Anatomy 0.000 title abstract 2
- 238000000520 microinjection Methods 0.000 abstract 2
- 230000003213 activating effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000002759 chromosomal effect Effects 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 210000001161 mammalian embryo Anatomy 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000392 somatic effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
- C12N15/8775—Murine embryos
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Environmental Sciences (AREA)
- Cell Biology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Farming Of Fish And Shellfish (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7200298P | 1998-01-21 | 1998-01-21 | |
| US8994098P | 1998-06-19 | 1998-06-19 | |
| US09/132,104 US6331659B1 (en) | 1998-01-21 | 1998-08-10 | Cumulus cells as nuclear donors |
| PCT/US1999/001144 WO1999037143A2 (en) | 1998-01-21 | 1999-01-20 | Full term development of animals from enucleated oocytes reconstituted with adult somatic cell nuclei |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1049372T3 true DK1049372T3 (da) | 2009-06-08 |
Family
ID=27372005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99902382T DK1049372T3 (da) | 1998-01-21 | 1999-01-20 | Full-term udvikling af dyr fra enukleerede oocyter rekonstitueret med adulte somatiske cellekerner |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6331659B1 (da) |
| EP (1) | EP1049372B1 (da) |
| JP (1) | JP3739652B2 (da) |
| KR (1) | KR20010040370A (da) |
| CN (1) | CN1200107C (da) |
| AT (1) | ATE424108T1 (da) |
| AU (1) | AU765170B2 (da) |
| BR (1) | BR9907193A (da) |
| CA (1) | CA2318070A1 (da) |
| DE (1) | DE69940498D1 (da) |
| DK (1) | DK1049372T3 (da) |
| ES (1) | ES2323560T3 (da) |
| IL (1) | IL137298A0 (da) |
| NZ (1) | NZ505728A (da) |
| WO (1) | WO1999037143A2 (da) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6664044B1 (en) * | 1997-06-19 | 2003-12-16 | Toyota Jidosha Kabushiki Kaisha | Method for conducting PCR protected from evaporation |
| US7241617B2 (en) * | 1998-07-03 | 2007-07-10 | Dnavec Research, Inc. | Sendai viral vectors comprising foreign genes inserted between the R1 and R2 Loci |
| US6781030B1 (en) * | 1998-11-02 | 2004-08-24 | Trustee Of Tufts College, Ballou Hall | Methods for cloning mammals using telophase oocytes |
| KR100417566B1 (ko) * | 1999-11-19 | 2004-02-05 | 한국생명공학연구원 | 체세포 핵치환 복제수정란의 대량생산방법 |
| WO2002000013A2 (en) * | 2000-06-23 | 2002-01-03 | Women And Infants Hospital Of Rhode Island | Meiotic spindle imaging in oocytes and uses therefor in in vitro fertilization |
| US6879713B1 (en) | 2000-06-23 | 2005-04-12 | Women & Infants Hospital Of Rhode Island | Meiotic spindle imaging in oocytes and uses therefor in in vitro fertilization |
| NZ524523A (en) | 2000-08-03 | 2006-02-24 | Therapeutic Human Polyclonals | Production of humanized antibodies in transgenic animals |
| WO2002019811A2 (en) * | 2000-09-06 | 2002-03-14 | Nexia Biotechnologies, Inc. | Generation of transgenic animals using nuclear transfer and oocytes at the germinal vesicle stage |
| FR2814642B1 (fr) | 2000-10-03 | 2005-07-01 | Ass Pour Le Dev De La Rech En | Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee |
| AU2002213033A1 (en) * | 2000-10-06 | 2002-04-15 | Advanced Cell Technology, Inc. | Method for generating cloned animals using chromosome shuffling |
| WO2002045490A2 (en) * | 2000-12-05 | 2002-06-13 | Université de Montréal | Method of cloning animals |
| ATE466089T1 (de) | 2000-12-22 | 2010-05-15 | Agronomique Inst Nat Rech | Positionsunabhängige und gewebespezifische expression eines transgens in der milch eines transgen-tieres |
| US20040040051A1 (en) * | 2001-01-19 | 2004-02-26 | Whitehead Institute For Biomedical Research | Generation of non-human mammals by nuclear cloning |
| US20020116732A1 (en) * | 2001-02-13 | 2002-08-22 | Leandro Christmann | Microinjection assembly and methods for microinjecting and reimplanting avian eggs |
| US7339090B2 (en) | 2001-02-13 | 2008-03-04 | Avigenics, Inc. | Microinjection devices and methods of use |
| US20080124787A1 (en) * | 2001-02-13 | 2008-05-29 | Avigenics, Inc. | Microinjection devices and methods of use |
| CA2438832A1 (en) | 2001-02-23 | 2002-09-06 | Elan Pharmaceuticals, Inc. | Transgenic knockouts of bace-1 |
| JP3842597B2 (ja) * | 2001-08-14 | 2006-11-08 | 家畜受精卵移植技術研究組合 | Ｇ１期細胞の収集方法及び該細胞を用いた核移植方法 |
| US20040006157A1 (en) * | 2002-04-26 | 2004-01-08 | Gloster Daniel F. | Ultra violet curable 100 percent solids inks |
| US7612250B2 (en) * | 2002-07-29 | 2009-11-03 | Trustees Of Tufts College | Nuclear transfer embryo formation method |
| FR2855183B1 (fr) | 2003-05-23 | 2005-08-12 | Agronomique Inst Nat Rech | Procede de clonage du rat par transfert nucleaire |
| PE20081216A1 (es) | 2006-09-01 | 2008-09-04 | Therapeutic Human Polyclonals Inc | Expresion mejorada de la inmunoglobulina humana o humanizada en animales transgenicos no humanos |
| WO2008085891A1 (en) * | 2007-01-05 | 2008-07-17 | Worcester Polytechnic Institute | Oocyte spindle-associated factors improve somatic cell cloning |
| KR100829426B1 (ko) | 2007-01-17 | 2008-05-15 | 재단법인서울대학교산학협력재단 | 복제개의 생산 방법 |
| KR100868245B1 (ko) | 2007-05-29 | 2008-11-11 | 강원대학교산학협력단 | 데메콜친 처리에 의한 효율적인 복제 동물의 생산방법 |
| EP2987498B1 (en) | 2008-05-02 | 2017-07-05 | Laboratoire Français du Fractionnement et des Biotechnologies | Treatment of bleeding with low half-life fibrinogen |
| EP2267153A1 (en) | 2009-05-26 | 2010-12-29 | Université Claude Bernard Lyon 1 | Identification of netrin-1 receptor unc5c gene mutation in solid cancers |
| EP2603581B1 (en) | 2010-08-11 | 2019-07-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Cocultures of cumulus cells and embryos during in vitro fertilization procedures |
| US10017733B2 (en) * | 2013-02-15 | 2018-07-10 | Sung Kwang Medical Foundation | Production of parthenogenetic stem cells and patient-specific human embryonic stem cells using somatic cell nuclear transfer |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4994384A (en) | 1986-12-31 | 1991-02-19 | W. R. Grace & Co.-Conn. | Multiplying bovine embryos |
| US5057420A (en) | 1987-06-05 | 1991-10-15 | Granada Biosciences, Inc. | Bovine nuclear transplantation |
| CA2091052A1 (en) | 1992-03-04 | 1993-09-05 | Steven L. Stice | Procedure for bovine nuclear transfer |
| CA2092258A1 (en) | 1992-12-30 | 1994-07-01 | Steven L. Stice | Synchronized donor cells for bovine nuclear transfer |
| US5480772A (en) | 1993-02-03 | 1996-01-02 | Brandeis University | In vitro activation of a nucleus |
| US5496720A (en) | 1993-02-10 | 1996-03-05 | Susko-Parrish; Joan L. | Parthenogenic oocyte activation |
| AU1439295A (en) | 1993-12-17 | 1995-07-03 | Abs Global, Inc. | Ungulate preblastocyst derived embryonic stem cells and use thereof to produce cloned transgenic and chimeric ungulates |
| WO1995017500A1 (en) | 1993-12-23 | 1995-06-29 | Abs Global, Inc. | Embryonic stem cells as nuclear donors and nuclear transfer techniques to produce chimeric and transgenic animals |
| GB9417831D0 (en) | 1994-09-05 | 1994-10-26 | Biotech & Biolog Scien Res | Biological manipulation |
| GB9517780D0 (en) | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| GB9517779D0 (en) | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| US5905042A (en) | 1996-04-01 | 1999-05-18 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Cultured inner cell mass cell lines derived from bovine or porcine embryos |
| EP0934403A4 (en) | 1996-08-19 | 2001-03-14 | Univ Massachusetts | ROWS OF EMBRYONIC OR STRAIN-LIKE CELLS PRODUCED BY CROSS NUCLEAR TRANSPLANTATION OF SPECIES |
| US5945577A (en) * | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
| US6235969B1 (en) | 1997-01-10 | 2001-05-22 | University Of Massachusetts | Cloning pigs using donor nuclei from non-quiescent differentiated cells |
| NZ337495A (en) * | 1997-03-06 | 2001-06-29 | Infigen Inc | Bovine primordial germ cells and their use in cloning |
| US6011197A (en) * | 1997-03-06 | 2000-01-04 | Infigen, Inc. | Method of cloning bovines using reprogrammed non-embryonic bovine cells |
| CA2294916A1 (en) | 1997-07-03 | 1999-01-14 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth As Represented By Its Amherst Campus | Cloning using donor nuclei from non-serum starved, differentiated cells |
-
1998
- 1998-08-10 US US09/132,104 patent/US6331659B1/en not_active Expired - Lifetime
-
1999
- 1999-01-20 AT AT99902382T patent/ATE424108T1/de active
- 1999-01-20 NZ NZ505728A patent/NZ505728A/xx unknown
- 1999-01-20 ES ES99902382T patent/ES2323560T3/es not_active Expired - Lifetime
- 1999-01-20 CN CNB998039071A patent/CN1200107C/zh not_active Expired - Fee Related
- 1999-01-20 JP JP2000528150A patent/JP3739652B2/ja not_active Expired - Lifetime
- 1999-01-20 KR KR1020007007951A patent/KR20010040370A/ko not_active Application Discontinuation
- 1999-01-20 DE DE69940498T patent/DE69940498D1/de not_active Expired - Lifetime
- 1999-01-20 IL IL13729899A patent/IL137298A0/xx unknown
- 1999-01-20 WO PCT/US1999/001144 patent/WO1999037143A2/en not_active Application Discontinuation
- 1999-01-20 BR BR9907193-2A patent/BR9907193A/pt not_active IP Right Cessation
- 1999-01-20 CA CA002318070A patent/CA2318070A1/en not_active Abandoned
- 1999-01-20 AU AU22377/99A patent/AU765170B2/en not_active Expired
- 1999-01-20 EP EP99902382A patent/EP1049372B1/en not_active Expired - Lifetime
- 1999-01-20 DK DK99902382T patent/DK1049372T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999037143A3 (en) | 2000-02-03 |
| ATE424108T1 (de) | 2009-03-15 |
| NZ505728A (en) | 2003-06-30 |
| JP2002500864A (ja) | 2002-01-15 |
| WO1999037143A2 (en) | 1999-07-29 |
| US6331659B1 (en) | 2001-12-18 |
| AU2237799A (en) | 1999-08-09 |
| EP1049372B1 (en) | 2009-03-04 |
| AU765170B2 (en) | 2003-09-11 |
| CA2318070A1 (en) | 1999-07-29 |
| EP1049372A2 (en) | 2000-11-08 |
| BR9907193A (pt) | 2000-10-17 |
| IL137298A0 (en) | 2001-07-24 |
| KR20010040370A (ko) | 2001-05-15 |
| JP3739652B2 (ja) | 2006-01-25 |
| CN1306390A (zh) | 2001-08-01 |
| DE69940498D1 (de) | 2009-04-16 |
| ES2323560T3 (es) | 2009-07-20 |
| CN1200107C (zh) | 2005-05-04 |
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