NO20075758L - Polymorfer av 3-0-(3',3'-dimetylsuccinyl) betulin syre di-N-metyl-D-glukamin - Google Patents

Polymorfer av 3-0-(3',3'-dimetylsuccinyl) betulin syre di-N-metyl-D-glukamin

Info

Publication number
NO20075758L
NO20075758L NO20075758A NO20075758A NO20075758L NO 20075758 L NO20075758 L NO 20075758L NO 20075758 A NO20075758 A NO 20075758A NO 20075758 A NO20075758 A NO 20075758A NO 20075758 L NO20075758 L NO 20075758L
Authority
NO
Norway
Prior art keywords
dimethylsuccinyl
methyl
betulinic acid
glucamine
polymorphs
Prior art date
Application number
NO20075758A
Other languages
English (en)
Inventor
Michael O'neil
Gary G Sweetapple
Randall M Walker
Arndt Err
Gunter Koch
David E Martin
Original Assignee
Panacos Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacos Pharmaceuticals Inc filed Critical Panacos Pharmaceuticals Inc
Publication of NO20075758L publication Critical patent/NO20075758L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Den foreliggende oppfinnelsen er relatert til krystallinske polymorfer av 3-O-(3',3'-dimetylsuccinyl) betulinsyre di-N-metyl-D-glukamin, farmasøytiske sammensetninger av den samme og anvendelse av det samme som et aktivt farmasøytisk middel i behandlingen av HIV relaterte lidelser.
NO20075758A 2005-04-12 2007-11-09 Polymorfer av 3-0-(3',3'-dimetylsuccinyl) betulin syre di-N-metyl-D-glukamin NO20075758L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67022705P 2005-04-12 2005-04-12
PCT/US2006/013640 WO2006110810A2 (en) 2005-04-12 2006-04-12 Polymorphs of 3-o-(3',3'-dimethylsuccinyl) betulinic acid di-n-methyl-d-glucamine

Publications (1)

Publication Number Publication Date
NO20075758L true NO20075758L (no) 2008-01-10

Family

ID=37087667

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20075758A NO20075758L (no) 2005-04-12 2007-11-09 Polymorfer av 3-0-(3',3'-dimetylsuccinyl) betulin syre di-N-metyl-D-glukamin

Country Status (14)

Country Link
US (1) US7799768B2 (no)
EP (1) EP1868613B1 (no)
JP (1) JP2008535923A (no)
CN (1) CN101160132A (no)
AT (1) ATE548043T1 (no)
AU (1) AU2006235486A1 (no)
BR (1) BRPI0610668A2 (no)
CA (1) CA2604720A1 (no)
ES (1) ES2383534T3 (no)
IL (1) IL186058A0 (no)
MX (1) MX2007011981A (no)
NO (1) NO20075758L (no)
RU (1) RU2007141631A (no)
WO (1) WO2006110810A2 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR063546A1 (es) 2006-11-03 2009-01-28 Panacos Pharmaceuticals Inc DERIVADOS DE TRITERPENO, METODOS PARA SU PREPARACION, COMPOSICIONES FARMACEUTICAS QUE LOS COMPRENDEN Y SU USO EN LA FABRICACION DE MEDICAMENTOS PARA EL TRATAMIENTO DE INFECCIoN POR EL VIRUS VIH.
WO2008091532A1 (en) * 2007-01-19 2008-07-31 Panacos Pharmaceuticals, Inc. Salts of 3-o-(3',3'-dimethylsuccinyl)betulinic acid and solid state forms thereof
US20080294107A1 (en) * 2007-05-22 2008-11-27 Convergent Medical Solutions, Inc. Multiple robotic injections of prenatal medications based on scanned image
US20080294115A1 (en) * 2007-05-22 2008-11-27 Chen Raymond H Microscopic Tumor Injection Treatment
US20080294141A1 (en) * 2007-05-22 2008-11-27 Convergent Medical Solutions, Inc. Multiple robotic injections of immunosuppressive drugs based on scanned image
US20080294106A1 (en) * 2007-05-22 2008-11-27 Convergent Medical Solutions, Inc. Multiple robotic injections of anesthesia based on scanned image
WO2009146240A1 (en) * 2008-05-27 2009-12-03 Convergent Medical Solutions, Inc. Multiple robotic injections based on scanned image

Family Cites Families (25)

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Publication number Priority date Publication date Assignee Title
GB1415601A (en) 1973-03-14 1975-11-26 Biorex Laboratories Ltd Dihydrobetulinic acid derivatives
JPH01143832A (ja) 1987-12-01 1989-06-06 Toa Nenryo Kogyo Kk 制癌剤
EP0610295A1 (en) 1991-10-16 1994-08-17 Schering Corporation Lipophilic oligosaccharide antibiotic salt compositions
FR2683531B1 (fr) 1991-11-13 1993-12-31 Rhone Poulenc Rorer Sa Nouveaux derives du lupane, leur preparation et les compositions pharmaceutiques qui les contiennent.
US5643884A (en) 1993-08-09 1997-07-01 Glycomed Incorporated Lupane triterpenoid derivatives
US5679828A (en) 1995-06-05 1997-10-21 Biotech Research Labs, Inc. Betulinic acid and dihydrobetulinic acid derivatives and uses therefor
US5648888A (en) * 1995-12-27 1997-07-15 Hydro-Quebec Power distribution substation
US5776912A (en) 1996-12-20 1998-07-07 Schering Corporation Lipophilic oligosaccharide antibiotic compositions
US6043245A (en) 1997-09-25 2000-03-28 Schering Corporation Tetrahydrofuran antifungal phosphate
US6670345B1 (en) 1997-09-30 2003-12-30 Dabur Research Foundation Betulinic acid derivatives for inhabiting cancer growth and process for the manufacture of betulinic acid
CA2322868C (en) 1998-03-02 2009-02-03 The University Of North Carolina At Chapel Hill Acylated betulin and dihydrobetulin derivatives, preparation thereof and use thereof
US6043254A (en) * 1998-04-03 2000-03-28 Boehringer Ingelheim Pharma Kg Indolinones having kinase-inhibiting activity
WO2000059492A2 (en) 1999-04-07 2000-10-12 Washington State University Research Foundation Anti-tumor activity of vitamin e, cholesterol, taxol and betulinic acid derivatives
US6147077A (en) 1999-04-29 2000-11-14 Sepracor Inc. 2R,4S-hydroxyitraconazole isomers
RU2174982C2 (ru) 1999-11-05 2001-10-20 Институт органической химии Уфимского научного центра РАН 3,28-ди-о-никотинат бетулина, проявляющий гепатопротекторную и анти-вич активность
WO2001085700A2 (en) * 2000-05-08 2001-11-15 Janssen Pharmaceutica N.V. Hiv replication inhibiting pyrimidines and triazines
CA2424013A1 (en) 2000-09-29 2002-04-04 Regents Of The University Of Minnesota Triterpenes having fungicidal activity against yeast
JP4179768B2 (ja) 2001-10-01 2008-11-12 ポーラ化成工業株式会社 トリテルペン誘導体及びそれを含有する化合物
US7365221B2 (en) 2002-09-26 2008-04-29 Panacos Pharmaceuticals, Inc. Monoacylated betulin and dihydrobetulin derivatives, preparation thereof and use thereof
NZ538896A (en) 2002-09-26 2007-10-26 Niigata University Of Pharmacy Monoacylated betulin and dihydrobetulin derivatives, preparation thereof and use thereof
WO2005030790A1 (en) 2003-09-26 2005-04-07 Panacos Pharmaceuticals, Inc. Novel triterpene derivatives, preparation thereof and use thereof
JP2007529544A (ja) 2004-03-17 2007-10-25 パナコス ファーマシューティカルズ， インコーポレイテッド ３−ｏ−（３’，３’−ジメチルスクシニル）ベツリン酸の製薬的な塩
TW200628161A (en) 2004-11-12 2006-08-16 Panacos Pharmaceuticals Inc Novel betulin derivatives, preparation thereof and use thereof
ZA200805703B (en) 2005-12-16 2009-10-28 Panacos Pharmaceuticals Inc Preparation of pharmaceutical salts of 3-0-(3',3'-dimethyl-succinyl) betulinic acid
US8180205B2 (en) 2007-01-12 2012-05-15 Guoning Yao Electrothermal oil radiator

Also Published As

Publication number Publication date
AU2006235486A1 (en) 2006-10-19
BRPI0610668A2 (pt) 2010-07-13
IL186058A0 (en) 2008-08-07
RU2007141631A (ru) 2009-05-20
CA2604720A1 (en) 2006-10-19
JP2008535923A (ja) 2008-09-04
ES2383534T3 (es) 2012-06-22
WO2006110810A2 (en) 2006-10-19
EP1868613A2 (en) 2007-12-26
MX2007011981A (es) 2007-12-05
EP1868613B1 (en) 2012-03-07
US7799768B2 (en) 2010-09-21
ATE548043T1 (de) 2012-03-15
US20060252704A1 (en) 2006-11-09
EP1868613A4 (en) 2008-04-30
CN101160132A (zh) 2008-04-09
WO2006110810A3 (en) 2007-03-29

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