NO20073548L - Fremstillingsprosess for N-substituerte salicylamider - Google Patents

Fremstillingsprosess for N-substituerte salicylamider

Info

Publication number
NO20073548L
NO20073548L NO20073548A NO20073548A NO20073548L NO 20073548 L NO20073548 L NO 20073548L NO 20073548 A NO20073548 A NO 20073548A NO 20073548 A NO20073548 A NO 20073548A NO 20073548 L NO20073548 L NO 20073548L
Authority
NO
Norway
Prior art keywords
preparation process
substituted salicylamides
preparation
substituted
relates
Prior art date
Application number
NO20073548A
Other languages
English (en)
Other versions
NO338969B1 (no
Inventor
Bernhard Riss
Ulrich Meier
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34090175&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20073548(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20073548L publication Critical patent/NO20073548L/no
Publication of NO338969B1 publication Critical patent/NO338969B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Foreliggende oppfinnelse angår en fremgangsmåte for fremstilling av N-substituert salisylamider eller derivater derav, og deres salter, hydrater og solvater. Særlig angår oppfinnelsen en fremgangsmåte for fremstilling av N-(5-klorsalisyloyl)-8aminkaprylsyre (5-CNAQ) og dens korresponderende dinatriummonohydrat.
NO20073548A 2004-12-16 2007-07-09 Fremgangsmåte for fremstilling av N-substituerte salisylamider NO338969B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0427603.6A GB0427603D0 (en) 2004-12-16 2004-12-16 Organic compounds
PCT/EP2005/013454 WO2006063821A1 (en) 2004-12-16 2005-12-14 Manufacture process of n-substituted salicylamides

Publications (2)

Publication Number Publication Date
NO20073548L true NO20073548L (no) 2007-09-17
NO338969B1 NO338969B1 (no) 2016-11-07

Family

ID=34090175

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073548A NO338969B1 (no) 2004-12-16 2007-07-09 Fremgangsmåte for fremstilling av N-substituerte salisylamider

Country Status (24)

Country Link
US (1) US8461385B2 (no)
EP (2) EP1838664B1 (no)
JP (1) JP5224816B2 (no)
KR (1) KR101287233B1 (no)
CN (1) CN101080384B (no)
AR (1) AR055007A1 (no)
AU (1) AU2005315850B2 (no)
BR (1) BRPI0519327A2 (no)
CA (1) CA2587213C (no)
ES (1) ES2547349T3 (no)
GB (1) GB0427603D0 (no)
GT (1) GT200500353A (no)
IL (1) IL183366A0 (no)
MA (1) MA29092B1 (no)
MX (1) MX2007007211A (no)
NO (1) NO338969B1 (no)
PE (1) PE20060740A1 (no)
PL (1) PL1838664T3 (no)
PT (1) PT1838664E (no)
RU (1) RU2404158C2 (no)
TN (1) TNSN07229A1 (no)
TW (1) TW200635880A (no)
WO (1) WO2006063821A1 (no)
ZA (1) ZA200703826B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2507196C2 (ru) * 2005-09-19 2014-02-20 Эмисфире Текнолоджис, Инк. Кристаллические формы динатриевой соли n-(5-хлорсалицилоил)-8-аминокаприловой кислоты
DK2215047T3 (da) 2007-11-02 2014-02-03 Emisphere Tech Inc Fremgangsmåde til behandling af vitamin b12-mangel
CN109473182B (zh) * 2018-11-12 2021-10-19 北京北排科技有限公司 一种基于深度信念网络的mbr膜透水率智能检测方法
CA3141383A1 (en) * 2019-05-20 2020-11-26 Lonza Guangzhou Pharmaceutical Ltd. Method for preparation of carsalam
CN115260116B (zh) * 2022-08-19 2024-04-12 株洲壹诺生物技术有限公司 8-(2-羟基苯甲酰胺基)辛酸钠及苯并噁嗪-2,4-二酮和8-溴辛酸乙酯的制法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2235854T3 (es) * 1999-04-05 2005-07-16 Emisphere Technologies, Inc. Sales disodicas, monohidratos y solvatos etanolicos para aportar agentes activos.
HUP0202384A3 (en) * 1999-06-25 2003-03-28 Inst For Pharm Discovery Inc Substituted phenoxyacetic acids
EP1284724B1 (en) 2000-03-21 2012-04-18 Emisphere Technologies, Inc. Method of preparing alkylated salicylamides via a dicarboxylate intermediate
AU2001275231A1 (en) 2000-06-02 2001-12-11 Emisphere Technologies, Inc. Method of preparing salicylamides
AU2001273153B2 (en) * 2000-06-29 2005-11-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
AU2001296865A1 (en) * 2000-09-06 2002-03-22 Emisphere Technologies, Inc. (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents
US7049283B2 (en) * 2000-12-06 2006-05-23 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents
EP1469827B1 (en) * 2002-01-09 2017-12-27 Emisphere Technologies, Inc. Polymorphs of sodium 4- (4-chloro-2-hydroxybenzoyl)amino butanoate
CN1332711C (zh) 2002-02-20 2007-08-22 埃米球科技有限公司 施用glp－1分子的方法
US20050054557A1 (en) 2002-05-09 2005-03-10 Goldberg Michael M. Compositions for delivering parathyroid hormone and calcitonin

Also Published As

Publication number Publication date
KR20070086276A (ko) 2007-08-27
MX2007007211A (es) 2007-08-15
CN101080384A (zh) 2007-11-28
AR055007A1 (es) 2007-08-01
IL183366A0 (en) 2007-09-20
JP2008524142A (ja) 2008-07-10
PE20060740A1 (es) 2006-09-04
US20090253811A1 (en) 2009-10-08
CA2587213C (en) 2015-05-19
NO338969B1 (no) 2016-11-07
PT1838664E (pt) 2015-10-16
JP5224816B2 (ja) 2013-07-03
AU2005315850B2 (en) 2009-11-05
PL1838664T3 (pl) 2016-04-29
ZA200703826B (en) 2008-08-27
EP1838664A1 (en) 2007-10-03
RU2404158C2 (ru) 2010-11-20
GB0427603D0 (en) 2005-01-19
WO2006063821A1 (en) 2006-06-22
US8461385B2 (en) 2013-06-11
ES2547349T3 (es) 2015-10-05
TW200635880A (en) 2006-10-16
MA29092B1 (fr) 2007-12-03
CN101080384B (zh) 2011-06-15
CA2587213A1 (en) 2006-06-22
EP2955171A1 (en) 2015-12-16
AU2005315850A1 (en) 2006-06-22
EP1838664B1 (en) 2015-07-15
GT200500353A (es) 2006-07-17
RU2007126972A (ru) 2009-01-27
BRPI0519327A2 (pt) 2009-01-13
KR101287233B1 (ko) 2013-07-17
TNSN07229A1 (en) 2008-11-21

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