AR055007A1 - Proceso de fabricacion de salicilamidas n-sustituidas - Google Patents

Proceso de fabricacion de salicilamidas n-sustituidas

Info

Publication number
AR055007A1
AR055007A1 ARP050105245A ARP050105245A AR055007A1 AR 055007 A1 AR055007 A1 AR 055007A1 AR P050105245 A ARP050105245 A AR P050105245A AR P050105245 A ARP050105245 A AR P050105245A AR 055007 A1 AR055007 A1 AR 055007A1
Authority
AR
Argentina
Prior art keywords
substituted
salicilamids
manufacturing process
refers
preparation
Prior art date
Application number
ARP050105245A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34090175&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR055007(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR055007A1 publication Critical patent/AR055007A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La presente se refiere a un método para la preparacion de salicilamidas N-sustituidas o sus derivados, y sus sales, hidratos y solvatos. En particular, la presente se refiere a un método para la preparacion del ácido N-(5-cloro-saliciloil)-8-amino- caprílico (5-CNAC) y su monohidrato disodico correspondiente.
ARP050105245A 2004-12-16 2005-12-14 Proceso de fabricacion de salicilamidas n-sustituidas AR055007A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0427603.6A GB0427603D0 (en) 2004-12-16 2004-12-16 Organic compounds

Publications (1)

Publication Number Publication Date
AR055007A1 true AR055007A1 (es) 2007-08-01

Family

ID=34090175

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050105245A AR055007A1 (es) 2004-12-16 2005-12-14 Proceso de fabricacion de salicilamidas n-sustituidas

Country Status (24)

Country Link
US (1) US8461385B2 (es)
EP (2) EP2955171A1 (es)
JP (1) JP5224816B2 (es)
KR (1) KR101287233B1 (es)
CN (1) CN101080384B (es)
AR (1) AR055007A1 (es)
AU (1) AU2005315850B2 (es)
BR (1) BRPI0519327A2 (es)
CA (1) CA2587213C (es)
ES (1) ES2547349T3 (es)
GB (1) GB0427603D0 (es)
GT (1) GT200500353A (es)
IL (1) IL183366A0 (es)
MA (1) MA29092B1 (es)
MX (1) MX2007007211A (es)
NO (1) NO338969B1 (es)
PE (1) PE20060740A1 (es)
PL (1) PL1838664T3 (es)
PT (1) PT1838664E (es)
RU (1) RU2404158C2 (es)
TN (1) TNSN07229A1 (es)
TW (1) TW200635880A (es)
WO (1) WO2006063821A1 (es)
ZA (1) ZA200703826B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007035718A2 (en) * 2005-09-19 2007-03-29 Emisphere Technologies, Inc. Crystalline forms of the di-sodium salt of n-(5-chlorosalicyloyl)-8-aminocaprylic acid
BRPI0817396C8 (pt) 2007-11-02 2021-05-25 Emisphere Tech Inc composição farmacêutica para tratar deficiência de vitamina b¹²
CN109473182B (zh) * 2018-11-12 2021-10-19 北京北排科技有限公司 一种基于深度信念网络的mbr膜透水率智能检测方法
ES2952567T3 (es) * 2019-05-20 2023-11-02 Lonza Guangzhou Pharmaceutical Ltd Método para la preparación de Carsalam
CN115260116B (zh) * 2022-08-19 2024-04-12 株洲壹诺生物技术有限公司 8-(2-羟基苯甲酰胺基)辛酸钠及苯并噁嗪-2,4-二酮和8-溴辛酸乙酯的制法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60017888T2 (de) * 1999-04-05 2006-01-19 Emisphere Technologies, Inc. Dinatrium-salze, monohydrate und ethanol-solvate
JP2003503381A (ja) * 1999-06-25 2003-01-28 ザ インスティテューツ フォア ファーマスーティカル ディスカヴァリー エルエルシー 置換フェノキシ酢酸
JP4799794B2 (ja) * 2000-03-21 2011-10-26 エミスフェアー・テクノロジーズ・インク ジカルボキシル化中間体を介してアルキル化サリチルアミドを調製する方法。
US7262325B2 (en) 2000-06-02 2007-08-28 Emisphere Technologies, Inc. Method of preparing salicylamides
MXPA02012855A (es) * 2000-06-29 2004-04-20 Emisphere Tech Inc Compuestos y composiciones para suministrar agentes activos.
EP1322595B1 (en) * 2000-09-06 2008-05-28 Emisphere Technologies, Inc. (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents
US7049283B2 (en) * 2000-12-06 2006-05-23 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents
JP4508646B2 (ja) * 2002-01-09 2010-07-21 エミスフェアー・テクノロジーズ・インク ４−［（４−クロロ−２−ヒドロキシベンゾイル）アミノ］ブタン酸ナトリウムの多形体
ES2614603T3 (es) * 2002-02-20 2017-06-01 Emisphere Technologies, Inc. Procedimiento de administración de moléculas GLP-1
US20050054557A1 (en) 2002-05-09 2005-03-10 Goldberg Michael M. Compositions for delivering parathyroid hormone and calcitonin

Also Published As

Publication number Publication date
EP1838664B1 (en) 2015-07-15
CA2587213C (en) 2015-05-19
MX2007007211A (es) 2007-08-15
GT200500353A (es) 2006-07-17
CA2587213A1 (en) 2006-06-22
RU2007126972A (ru) 2009-01-27
KR101287233B1 (ko) 2013-07-17
JP5224816B2 (ja) 2013-07-03
NO20073548L (no) 2007-09-17
US20090253811A1 (en) 2009-10-08
CN101080384A (zh) 2007-11-28
ZA200703826B (en) 2008-08-27
PE20060740A1 (es) 2006-09-04
IL183366A0 (en) 2007-09-20
US8461385B2 (en) 2013-06-11
NO338969B1 (no) 2016-11-07
BRPI0519327A2 (pt) 2009-01-13
AU2005315850B2 (en) 2009-11-05
EP2955171A1 (en) 2015-12-16
PL1838664T3 (pl) 2016-04-29
MA29092B1 (fr) 2007-12-03
CN101080384B (zh) 2011-06-15
JP2008524142A (ja) 2008-07-10
KR20070086276A (ko) 2007-08-27
PT1838664E (pt) 2015-10-16
GB0427603D0 (en) 2005-01-19
WO2006063821A1 (en) 2006-06-22
AU2005315850A1 (en) 2006-06-22
TW200635880A (en) 2006-10-16
RU2404158C2 (ru) 2010-11-20
ES2547349T3 (es) 2015-10-05
EP1838664A1 (en) 2007-10-03
TNSN07229A1 (en) 2008-11-21

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Legal Events

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FA Abandonment or withdrawal