NO20073549L - Fremgangsmate for fremstilling av organiske forbindelser - Google Patents

Fremgangsmate for fremstilling av organiske forbindelser

Info

Publication number
NO20073549L
NO20073549L NO20073549A NO20073549A NO20073549L NO 20073549 L NO20073549 L NO 20073549L NO 20073549 A NO20073549 A NO 20073549A NO 20073549 A NO20073549 A NO 20073549A NO 20073549 L NO20073549 L NO 20073549L
Authority
NO
Norway
Prior art keywords
preparation
organic compounds
derivatives
relates
present
Prior art date
Application number
NO20073549A
Other languages
English (en)
Other versions
NO338831B1 (no
Inventor
Bernhard Riss
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20073549L publication Critical patent/NO20073549L/no
Publication of NO338831B1 publication Critical patent/NO338831B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Den foreliggende oppfinnelsen vedrører en fremgangsmåte for fremstilling av N-subsituert salisylamider eller derivater derav og deres derivater, for eksempel deres salter. I særdeleshet vedrører den foreliggende oppfinnelsen en fremgangsmåte for fremstilling av N-(5-kIorsaIicyIoyI)-8-aminokaprylsyre (5-CNAQ) og dens tilsvarende dinatrium monohydrat.
NO20073549A 2004-12-16 2007-07-09 Fremgangsmåte for fremstilling av N-substituerte salisylamider NO338831B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0427600.2A GB0427600D0 (en) 2004-12-16 2004-12-16 Organic compounds
PCT/EP2005/013452 WO2006063819A2 (en) 2004-12-16 2005-12-14 Manufacture process of n-substituted salicylamides

Publications (2)

Publication Number Publication Date
NO20073549L true NO20073549L (no) 2007-09-07
NO338831B1 NO338831B1 (no) 2016-10-24

Family

ID=34090173

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073549A NO338831B1 (no) 2004-12-16 2007-07-09 Fremgangsmåte for fremstilling av N-substituerte salisylamider

Country Status (23)

Country Link
US (1) US8013184B2 (no)
EP (1) EP1828103B1 (no)
JP (1) JP5122297B2 (no)
KR (1) KR101277393B1 (no)
CN (1) CN101080381B (no)
AR (1) AR052268A1 (no)
AU (1) AU2005315848B2 (no)
BR (1) BRPI0519599A2 (no)
CA (1) CA2587428C (no)
ES (1) ES2555510T3 (no)
GB (1) GB0427600D0 (no)
GT (1) GT200500350A (no)
IL (1) IL183597A0 (no)
MA (1) MA29089B1 (no)
MX (1) MX2007007273A (no)
NO (1) NO338831B1 (no)
PE (1) PE20060741A1 (no)
PL (1) PL1828103T3 (no)
PT (1) PT1828103E (no)
RU (1) RU2411234C2 (no)
TN (1) TNSN07228A1 (no)
TW (1) TW200633955A (no)
WO (1) WO2006063819A2 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105641686A (zh) 2005-09-19 2016-06-08 爱密斯菲尔科技公司 N-(5-氯水杨酰基)-8-氨基辛酸的二钠盐的晶形
AU2008318423B2 (en) 2007-11-02 2013-12-05 Emisphere Technologies, Inc. Method of treating vitamin B12 deficiency
CN108689876B (zh) * 2018-06-28 2020-11-27 苏州东南药业股份有限公司 一种8-(2-羟基苯甲酰胺基)辛酸钠的制备方法
US20220339668A1 (en) * 2019-09-27 2022-10-27 Honda Motor Co., Ltd. Metal coating method
CN113620832B (zh) * 2020-05-07 2024-08-13 鲁南制药集团股份有限公司 一种非布司他中间体的制备方法
CN113861062A (zh) * 2021-10-28 2021-12-31 郑州大明药物科技有限公司 一种n-（8-[2-羟基苯甲酰基]-氨基）辛酸钠的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659826A (en) * 1983-11-28 1987-04-21 Lever Brothers Company Synthesis of salicylamides with improved yield and purity
HU211995B (en) * 1992-06-30 1996-01-29 Gyogyszerkutato Intezet Process to prepare novel benzoyl amino acid derivs. and pharmaceutical compns. contg.them
US5773647A (en) * 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
ES2267283T3 (es) * 1998-08-07 2007-03-01 Emisphere Technologies, Inc. Compuestos y composiciones para la administracion de agentes activos.
CA2369591C (en) * 1999-04-05 2011-06-14 Emisphere Technologies, Inc. Disodium salts, monohydrate, and ethanol solvates
ES2386263T3 (es) * 2000-03-21 2012-08-14 Emisphere Technologies, Inc. Método de preparación de salicilamidas alquiladas mediante un producto intermedio de dicarboxilato
CA2411754C (en) * 2000-06-29 2009-05-26 Emisphere Technologies, Inc. 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoic acid and compositions for delivering active agents
WO2003015822A1 (en) 2001-08-17 2003-02-27 Novartis Ag 5-cnac as oral delivery agent for parathyroid hormone fragments
CA2471144C (en) * 2002-01-09 2011-06-07 Emisphere Technologies, Inc. Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate
CN1446795A (zh) 2003-01-16 2003-10-08 华东理工大学 N－水杨酰－8－氨基辛酸钠的合成方法

Also Published As

Publication number Publication date
NO338831B1 (no) 2016-10-24
TNSN07228A1 (en) 2008-11-21
GB0427600D0 (en) 2005-01-19
US20090234010A1 (en) 2009-09-17
GT200500350A (es) 2006-07-17
EP1828103B1 (en) 2015-09-30
AU2005315848B2 (en) 2009-11-26
PE20060741A1 (es) 2006-09-04
PL1828103T3 (pl) 2016-05-31
JP2008524140A (ja) 2008-07-10
WO2006063819A3 (en) 2006-09-14
JP5122297B2 (ja) 2013-01-16
RU2007126973A (ru) 2009-01-27
CA2587428A1 (en) 2006-06-22
CN101080381A (zh) 2007-11-28
CA2587428C (en) 2013-10-08
BRPI0519599A2 (pt) 2009-02-25
KR20070086233A (ko) 2007-08-27
PT1828103E (pt) 2015-12-31
MX2007007273A (es) 2007-07-11
US8013184B2 (en) 2011-09-06
AU2005315848A1 (en) 2006-06-22
KR101277393B1 (ko) 2013-06-20
ES2555510T3 (es) 2016-01-04
EP1828103A2 (en) 2007-09-05
AR052268A1 (es) 2007-03-07
MA29089B1 (fr) 2007-12-03
TW200633955A (en) 2006-10-01
WO2006063819A2 (en) 2006-06-22
IL183597A0 (en) 2007-09-20
CN101080381B (zh) 2011-06-15
RU2411234C2 (ru) 2011-02-10

Similar Documents

Publication Publication Date Title
NO20056010L (no) Biaryloksymetylaren-karboksylsyrer
NO20090628L (no) Pyridizinon derivativater
NO20070432L (no) Pyrimidinureaderivater som kinaseinhibitorer
EA200501061A1 (ru) N-(1-бензил-2-оксо-2-(1-пиперазинил)этил)-1-пиперидинкарбоксамидные производные и родственные соединения в качестве cgrp-антагонистов для лечения головных болей
NO20085064L (no) 4,5-difenyl-pyrimidinyl-oksy eller -merkaptosubstituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter
EA200700096A1 (ru) Производные 2-карбамид-4-фенилтиазола, способ их получения и их применение в терапии
NO20081942L (no) Karbamoylbenzotriazolderivater som inhibitorer av lipaser og fosfolipaser
NO20073549L (no) Fremgangsmate for fremstilling av organiske forbindelser
NO20083708L (no) 4-Fenyl-tiazol-5-karboksylsyre og 4-fenyl-tiazol-5-karboksylmider som PLK1-inhibitorer
EP2336140A3 (en) Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents
NO20076448L (no) Novel piperidine carboxylic acid amide derivatives
NO20080394L (no) N-(arylalkyl)-1H-pyrrolopyridin-2-karboksamidderivater, fremstilling og anvendelse derav
NO20084186L (no) Nye aminer
DK1517890T3 (da) Kationisk substituerede diphenylazetidinoner, fremgangsmåde til deres fremstilling, lægemidler indeholdende disse forbindelser og deres anvendelse
NO20083738L (no) Sekundaere aminer som renininhibitorer
NO20063865L (no) Heterocyklisk substituerte 7-amino-4-kinolon-3-karboksylsyrederivater, fremgangsmate for fremstilling derav og deres anvendelse som medikamenter
UY27618A1 (es) Ésteres hidroxamato de ácido n-(4-fenil-sustituido)-antranílico
EA200701852A1 (ru) Производные аминокислот
DE602006009556D1 (de) Chinolin-derivate zur behandlung von mglur5-rezeptor-vermittelten erkrankungen
EA200600760A1 (ru) Новые соединения фенилпиридилпиперазина, способ их получения и фармацевтические композиции, содержащие их
NO20073548L (no) Fremstillingsprosess for N-substituerte salicylamider
SE0403086D0 (sv) Compounds
SG165397A1 (en) Crystalline forms of the di-sodium salt of n-(5-chlorosalicyloyl)-8- aminocaprylic acid
EA200300272A1 (ru) Новые производные хиназолина, способ их получения и фармацевтические композиции, содержащие их
NO20070869L (no) Fremstilling av hydrokloridsalter av tetrazolderivater

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees