NO20065609L - Piperazinderivater av alkyloksindoler. - Google Patents
Piperazinderivater av alkyloksindoler.Info
- Publication number
- NO20065609L NO20065609L NO20065609A NO20065609A NO20065609L NO 20065609 L NO20065609 L NO 20065609L NO 20065609 A NO20065609 A NO 20065609A NO 20065609 A NO20065609 A NO 20065609A NO 20065609 L NO20065609 L NO 20065609L
- Authority
- NO
- Norway
- Prior art keywords
- alkyloxindoles
- piperazine derivatives
- derivatives
- prophylaxis
- therapy
- Prior art date
Links
- 150000004885 piperazines Chemical class 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Det tilveiebringes nye indol-2-onderivater med Formel (I). Forbindelsene har en gunstig aktivitetsprofil for profylakse og terapi av forstyrrelser i sentralnervesystemet eller det kardiovaskulære system.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0400953A HUP0400953A3 (en) | 2004-05-11 | 2004-05-11 | Piperazine derivatives of alkyl-oxindoles, pharmaceutical compositions containing them, process for producing them and their use |
PCT/HU2005/000050 WO2005108364A1 (en) | 2004-05-11 | 2005-05-11 | Piperazine derivatives of alkyl oxindoles |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20065609L true NO20065609L (no) | 2007-02-05 |
Family
ID=89982207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20065609A NO20065609L (no) | 2004-05-11 | 2006-12-05 | Piperazinderivater av alkyloksindoler. |
Country Status (27)
Country | Link |
---|---|
US (1) | US7910591B2 (no) |
EP (1) | EP1751105B1 (no) |
JP (1) | JP2007537227A (no) |
CN (1) | CN101010296B (no) |
AT (1) | ATE412633T1 (no) |
AU (1) | AU2005240843B2 (no) |
BG (1) | BG109769A (no) |
CA (1) | CA2566096A1 (no) |
CZ (1) | CZ2006779A3 (no) |
DE (1) | DE602005010693D1 (no) |
DK (1) | DK1751105T3 (no) |
EA (1) | EA010789B1 (no) |
ES (1) | ES2319795T3 (no) |
HR (1) | HRP20060420A2 (no) |
HU (1) | HUP0400953A3 (no) |
IL (1) | IL179028A (no) |
MX (1) | MXPA06013068A (no) |
NO (1) | NO20065609L (no) |
NZ (1) | NZ551545A (no) |
PL (2) | PL381615A1 (no) |
PT (1) | PT1751105E (no) |
RS (1) | RS20060621A (no) |
SI (1) | SI1751105T1 (no) |
SK (1) | SK51102006A3 (no) |
UA (1) | UA84927C2 (no) |
WO (1) | WO2005108364A1 (no) |
ZA (1) | ZA200610345B (no) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0400953A3 (en) * | 2004-05-11 | 2008-02-28 | Egis Gyogyszergyar Nyilvanosan | Piperazine derivatives of alkyl-oxindoles, pharmaceutical compositions containing them, process for producing them and their use |
CN104163813B (zh) * | 2013-05-16 | 2017-02-01 | 广东东阳光药业有限公司 | 取代的吲哚化合物及其使用方法和用途 |
CN106243088B (zh) | 2015-06-03 | 2019-01-04 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4452808A (en) * | 1982-12-07 | 1984-06-05 | Smithkline Beckman Corporation | 4-Aminoalkyl-2(3H)-indolones |
MX173362B (es) * | 1987-03-02 | 1994-02-23 | Pfizer | Compuestos de piperazinil heterociclicos y procedimiento para su preparacion |
FR2635104B1 (fr) * | 1988-08-03 | 1992-04-30 | Synthelabo | Derives d'indolone, leur preparation et leur application en therapeutique |
GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
WO1998008816A1 (fr) * | 1996-08-26 | 1998-03-05 | Meiji Seika Kaisha, Ltd. | Derives d'indoxyle et psychotropes |
HUP0400953A3 (en) * | 2004-05-11 | 2008-02-28 | Egis Gyogyszergyar Nyilvanosan | Piperazine derivatives of alkyl-oxindoles, pharmaceutical compositions containing them, process for producing them and their use |
-
2004
- 2004-05-11 HU HU0400953A patent/HUP0400953A3/hu unknown
-
2005
- 2005-05-11 EA EA200602084A patent/EA010789B1/ru not_active IP Right Cessation
- 2005-05-11 AU AU2005240843A patent/AU2005240843B2/en not_active Expired - Fee Related
- 2005-05-11 CN CN2005800148934A patent/CN101010296B/zh not_active Expired - Fee Related
- 2005-05-11 SI SI200530564T patent/SI1751105T1/sl unknown
- 2005-05-11 NZ NZ551545A patent/NZ551545A/en unknown
- 2005-05-11 CZ CZ20060779A patent/CZ2006779A3/cs unknown
- 2005-05-11 MX MXPA06013068A patent/MXPA06013068A/es active IP Right Grant
- 2005-05-11 DK DK05745440T patent/DK1751105T3/da active
- 2005-05-11 PL PL381615A patent/PL381615A1/pl unknown
- 2005-05-11 SK SK5110-2006A patent/SK51102006A3/sk not_active Application Discontinuation
- 2005-05-11 PL PL05745440T patent/PL1751105T3/pl unknown
- 2005-05-11 ZA ZA200610345A patent/ZA200610345B/en unknown
- 2005-05-11 EP EP05745440A patent/EP1751105B1/en active Active
- 2005-05-11 DE DE602005010693T patent/DE602005010693D1/de active Active
- 2005-05-11 PT PT05745440T patent/PT1751105E/pt unknown
- 2005-05-11 AT AT05745440T patent/ATE412633T1/de active
- 2005-05-11 RS RSP-2006/0621A patent/RS20060621A/sr unknown
- 2005-05-11 UA UAA200613076A patent/UA84927C2/ru unknown
- 2005-05-11 JP JP2007512357A patent/JP2007537227A/ja not_active Ceased
- 2005-05-11 ES ES05745440T patent/ES2319795T3/es active Active
- 2005-05-11 US US11/596,465 patent/US7910591B2/en not_active Expired - Fee Related
- 2005-05-11 CA CA002566096A patent/CA2566096A1/en not_active Abandoned
- 2005-05-11 WO PCT/HU2005/000050 patent/WO2005108364A1/en active Application Filing
-
2006
- 2006-11-02 IL IL179028A patent/IL179028A/en not_active IP Right Cessation
- 2006-12-04 HR HR20060420A patent/HRP20060420A2/xx not_active Application Discontinuation
- 2006-12-05 NO NO20065609A patent/NO20065609L/no not_active Application Discontinuation
- 2006-12-11 BG BG109769A patent/BG109769A/bg unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20080981L (no) | Nitrocatechol-derivater som COMT-inhibitorer | |
DE60319158D1 (de) | Pyrazoloisoquinolinenderivaten als kinase inhibitoren | |
NO20056130L (no) | Nye substituerte 3-svovelindoler | |
NO20090166L (no) | Amino-imidazoloner og deres anvendelse som et medikament for behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerering og demens | |
NO20083214L (no) | Pyrimidinylarylurea-derivater som omdannes til FGF-inhibitorer | |
NO20090755L (no) | Amino-imidazoloner og deres anvendelse som et medikament for behandling av kognitiv svekkelse, Alzheimers sykdom, neurodegenerering og demens | |
NO20091590L (no) | Heterocykliske amidforbindelser anvendbare som kinaseinhibitorer | |
NZ598242A (en) | Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor and erythropoietin production inducer | |
NO20064599L (no) | Substituerte morfolin- og tiomorfolinderivater | |
CY1111206T1 (el) | Βενζοθειοφαινια υποκατεστημενα με πιπεραζινη για την αγωγη διανοητικων διαταραχων | |
NO20075624L (no) | Nye histamin H3-reseptorligander og deres terapeutiske anvendelser | |
NO20080445L (no) | Nye azetidinderivater som neurokininreseptorantagonister for behandling av gastrointestinale sykdommer | |
NO20052487L (no) | 1-(4-benzyl-piperazin-1-yl)-3-fenyl-propenonderivater. | |
NO20064895L (no) | 6,6-Bisykliske ring-substituerte heterobisykliske protein-kinase inhibitorer | |
CO5700748A2 (es) | Derivados de 4-(2-fenilsulfanil-fenil)-piperidina como inhibidores de recaptacion de serotonina | |
NO20075406L (no) | Pyrimidindionerivater som prokineticin-2-reseprorantagonister | |
NO20071504L (no) | Pyrimidinderivanter. | |
NO20070855L (no) | Arylidener for behandling av estrogenrelaterte reseptor-alfamedierte sykdommer. | |
NO20065456L (no) | Substituerte morfolinforbindelser for behandling av sykdommer i sentralnervesystemet | |
ATE494926T1 (de) | Neuartige p2x7r-antagonisten und ihre verwendung | |
NI200700032A (es) | Derivados arilsulfonilestilbeno para tratamiento de insomnio y afecciones relacionadas | |
ATE413392T1 (de) | Kondensierte heteroyralderivate und deren verwendung als p38-kinase-inhibitoren | |
NO20081804L (no) | Pyrazolforbindelser egnet til behandling av inflammasjon | |
CO5640133A2 (es) | Derivados de 4-(2-feniloxifenil)-piperidina o 1,2,3,6-tetrahidropiridina como inhibidores de la recaptacion de la serotonina | |
NO20065609L (no) | Piperazinderivater av alkyloksindoler. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |