NO20063920L - Koblingsreaksjoner som er nyttige i fremstillingen av (1H-tetrazol-5-yl)-bifenylderivater - Google Patents

Koblingsreaksjoner som er nyttige i fremstillingen av (1H-tetrazol-5-yl)-bifenylderivater

Info

Publication number
NO20063920L
NO20063920L NO20063920A NO20063920A NO20063920L NO 20063920 L NO20063920 L NO 20063920L NO 20063920 A NO20063920 A NO 20063920A NO 20063920 A NO20063920 A NO 20063920A NO 20063920 L NO20063920 L NO 20063920L
Authority
NO
Norway
Prior art keywords
tetrazol
preparation
coupling reactions
biphenyl derivatives
reactions useful
Prior art date
Application number
NO20063920A
Other languages
English (en)
Inventor
Hans Hirt
Christoph Krell
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20063920L publication Critical patent/NO20063920L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Den foreliggende oppfinnelsen vedrører en prosess for produksjonen av intermediater som kan anvendes for produksjonen av ARBer også kalt angiotension II reseptor-antagonister eller AT1 reseptorantagonister) som omfatter som et felles strukturelt trekk en (IH-etrazol-5-yl)-bifenylring.
NO20063920A 2004-02-02 2006-09-01 Koblingsreaksjoner som er nyttige i fremstillingen av (1H-tetrazol-5-yl)-bifenylderivater NO20063920L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0402262.0A GB0402262D0 (en) 2004-02-02 2004-02-02 Process for the manufacture of organic compounds
PCT/EP2005/000978 WO2005075462A1 (en) 2004-02-02 2005-02-01 Coupling reactions useful in the preparation of (1h-tetrazol-5-yl)-biphenyl derivatives

Publications (1)

Publication Number Publication Date
NO20063920L true NO20063920L (no) 2006-10-30

Family

ID=31985494

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063920A NO20063920L (no) 2004-02-02 2006-09-01 Koblingsreaksjoner som er nyttige i fremstillingen av (1H-tetrazol-5-yl)-bifenylderivater

Country Status (19)

Country Link
US (2) US7700784B2 (no)
EP (2) EP2246348A1 (no)
JP (1) JP2007519684A (no)
KR (1) KR20060128993A (no)
CN (1) CN100528868C (no)
AU (1) AU2005211500B2 (no)
BR (1) BRPI0507352A (no)
CA (1) CA2553246A1 (no)
CO (1) CO5700717A2 (no)
EC (1) ECSP066727A (no)
GB (1) GB0402262D0 (no)
IL (2) IL176904A0 (no)
MA (1) MA28427B1 (no)
NO (1) NO20063920L (no)
NZ (1) NZ548690A (no)
RU (2) RU2426728C2 (no)
TN (1) TNSN06238A1 (no)
WO (1) WO2005075462A1 (no)
ZA (1) ZA200605462B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0222056D0 (en) * 2002-09-23 2002-10-30 Novartis Ag Process for the manufacture of organic compounds
JP5023720B2 (ja) * 2006-08-04 2012-09-12 東ソー株式会社 ハロゲン化ビフェニル類の製造方法
SI3067043T1 (sl) * 2007-11-06 2023-04-28 Novartis Ag Farmacevtski sestavki na osnovi superstruktur antagonista/blokatorja angiotenzinskega receptorja (ARB) in zaviralca nevtralne endopeptidaze (NEP)
PE20091364A1 (es) 2008-01-17 2009-10-13 Novartis Ag Proceso para la preparacion de inhibidores de nep
JP5203144B2 (ja) * 2008-11-07 2013-06-05 東ソー株式会社 スチレン類の製造方法
JP5261140B2 (ja) * 2008-11-07 2013-08-14 東ソー株式会社 ビニル芳香族化合物の製造方法
KR101476937B1 (ko) 2010-08-23 2014-12-24 노파르티스 아게 Ｎｅｐ 억제제의 제조를 위한 중간체의 제조 방법
ES2589977T3 (es) * 2010-08-27 2016-11-17 Teijin Pharma Limited Método para la producción de derivados heterocíclicos sustituidos con fenilos mediante medios de método de acoplamiento utilizando un compuesto de palladio
CN103467341B (zh) * 2013-08-29 2015-02-25 河南师范大学 一种沙坦联苯的制备方法
CN104987327A (zh) * 2015-07-13 2015-10-21 朱绍清 一种四唑类衍生物的催化合成方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
US4874867A (en) * 1987-05-22 1989-10-17 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
ATE250587T1 (de) 1989-06-14 2003-10-15 Smithkline Beecham Corp Imidazoalkensäure
DE122007000050I1 (de) 1990-02-19 2007-11-08 Novartis Ag Acylverbindungen
GB9005354D0 (en) * 1990-03-09 1990-05-02 Glaxo Group Ltd Chemical compounds
NZ237476A (en) 1990-03-20 1994-01-26 Sanofi Sa N-substituted heterocyclic compounds and pharmaceutical compositions.
US5196444A (en) 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
IS1756B (is) 1991-02-21 2000-12-28 Sankyo Company Limited Hliðstæðuaðferð til framleiðslu 1-Biphenylmethylimidazole afleiða
TW226375B (no) 1991-10-24 1994-07-11 American Home Prod
US5310928A (en) * 1991-11-18 1994-05-10 E. I. Du Pont De Nemours And Company Process for preparing biphenyltetrazole compounds
US5206374A (en) * 1991-11-18 1993-04-27 E. I. Du Pont De Nemours And Company Process for preparing tetrazolylphenylboronic acid intermediates
EP0550313A1 (fr) 1991-12-30 1993-07-07 Synthelabo Nouveaux dérivés de 2-(tétrazol-5-yl)-(1,1'-biphényle), leur préparation et leur utilisation comme intermédiaires de synthèse
FR2688503B1 (fr) * 1992-03-16 1994-05-06 Synthelabo Procede de preparation de derives de 2-(tetrazol-5-yl)-[1,1'-biphenyle].
US5468867A (en) * 1994-05-27 1995-11-21 Syntex (U.S.A.) Inc. Process for preparing1-butyl-2-[2'-(2H-tetrazol-5-yl)biphenyl-4-ylmethyl1-1H-indole-3-carboxylic acid
EP0788487B1 (en) 1994-10-27 2001-07-25 Novartis AG Process for the preparation of tetrazoles
JP3763869B2 (ja) * 1994-12-26 2006-04-05 東ソー・ファインケム株式会社 ビフェニル化合物の製造方法
US5922898A (en) * 1997-04-08 1999-07-13 Catalytica Pharmaceuticals, Inc. Process for preparing biaryl compounds
DE10057679A1 (de) * 2000-11-21 2002-05-29 Forschungszentrum Juelich Gmbh Brennstoffzellenstapel mit Kreislaufführung
BR0313000A (pt) * 2002-07-19 2005-07-12 Memory Pharm Corp Compostos, composição farmacêutica e método para efetuar a inibição da enzima pde4, realçar a cognição e/ou tratar a psicose em um paciente
GB0222056D0 (en) * 2002-09-23 2002-10-30 Novartis Ag Process for the manufacture of organic compounds
US7038060B2 (en) * 2003-02-05 2006-05-02 Teva Pharmaceutical Industries Ltd. Synthesis of 2-butyl-3-(2′-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspiro[4.4]-non-ene-4-one
KR20060027801A (ko) 2003-06-05 2006-03-28 제넨테크, 인크. Ｂ 세포 장애에 대한 조합 요법

Also Published As

Publication number Publication date
GB0402262D0 (en) 2004-03-10
RU2426728C2 (ru) 2011-08-20
KR20060128993A (ko) 2006-12-14
ZA200605462B (en) 2009-06-24
AU2005211500A1 (en) 2005-08-18
CA2553246A1 (en) 2005-08-18
US20070129413A1 (en) 2007-06-07
TNSN06238A1 (en) 2007-12-03
EP2246348A1 (en) 2010-11-03
MA28427B1 (fr) 2007-02-01
US20100152458A1 (en) 2010-06-17
ECSP066727A (es) 2006-10-31
AU2005211500B2 (en) 2009-04-02
JP2007519684A (ja) 2007-07-19
RU2006131460A (ru) 2008-03-10
EP1716140A1 (en) 2006-11-02
CN1914197A (zh) 2007-02-14
NZ548690A (en) 2009-08-28
CO5700717A2 (es) 2006-11-30
CN100528868C (zh) 2009-08-19
US7700784B2 (en) 2010-04-20
BRPI0507352A (pt) 2007-07-03
IL176904A0 (en) 2006-12-10
WO2005075462A1 (en) 2005-08-18
IL208409A0 (en) 2011-08-01
RU2010136996A (ru) 2012-03-20

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