NO20062585L - Steroider med en blandet androgen- og progestagen profil - Google Patents

Steroider med en blandet androgen- og progestagen profil

Info

Publication number
NO20062585L
NO20062585L NO20062585A NO20062585A NO20062585L NO 20062585 L NO20062585 L NO 20062585L NO 20062585 A NO20062585 A NO 20062585A NO 20062585 A NO20062585 A NO 20062585A NO 20062585 L NO20062585 L NO 20062585L
Authority
NO
Norway
Prior art keywords
progestagen
profile
steroids
androgen
mixed
Prior art date
Application number
NO20062585A
Other languages
English (en)
Inventor
Dirk Leysen
Marcel Everet De Gooijer
Arij Jan Grootenhuis
Jaap Van Der Louw
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of NO20062585L publication Critical patent/NO20062585L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Foreliggende oppfinnelse tilveiebringer 19-nor-D-homosteroider, som har en blandet androgen/progestagen-profil, som er oralt aktiv, forhindrer trabekulær benmineraltetthets- (BMD) tap, og som ikke har levertoksisitet, som har en struktur i henhold til formel I: hvor R1 er O, eller NOR, der R er hydrogen, (Ci-6)alkyl eller (Ci-6)acyl, R2 er metyl eller etyl, og R3 er hydrogen eller (Ci-i5)acyl.
NO20062585A 2003-12-22 2006-06-06 Steroider med en blandet androgen- og progestagen profil NO20062585L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03104898 2003-12-22
PCT/EP2004/053475 WO2005061528A2 (en) 2003-12-22 2004-12-15 Steroids having a mixed androgenic and progestagenic profile

Publications (1)

Publication Number Publication Date
NO20062585L true NO20062585L (no) 2006-09-20

Family

ID=34707282

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062585A NO20062585L (no) 2003-12-22 2006-06-06 Steroider med en blandet androgen- og progestagen profil

Country Status (30)

Country Link
US (1) US7582622B2 (no)
EP (1) EP1720895B1 (no)
JP (1) JP2007515455A (no)
KR (1) KR20060123484A (no)
CN (1) CN1898258B (no)
AR (1) AR046966A1 (no)
AT (1) ATE373674T1 (no)
AU (1) AU2004303524A1 (no)
BR (1) BRPI0417781A (no)
CA (1) CA2549148A1 (no)
CY (1) CY1106935T1 (no)
DE (1) DE602004009107T2 (no)
DK (1) DK1720895T3 (no)
EC (1) ECSP066666A (no)
ES (1) ES2294569T3 (no)
HR (1) HRP20070492T3 (no)
IL (1) IL175890A0 (no)
IS (1) IS8488A (no)
MX (1) MXPA06007195A (no)
NO (1) NO20062585L (no)
NZ (1) NZ547772A (no)
PE (1) PE20050677A1 (no)
PL (1) PL1720895T3 (no)
PT (1) PT1720895E (no)
RU (1) RU2357972C2 (no)
SI (1) SI1720895T1 (no)
TW (1) TW200521134A (no)
UA (1) UA84037C2 (no)
WO (1) WO2005061528A2 (no)
ZA (1) ZA200604976B (no)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959322A (en) * 1960-09-22 1976-05-25 Herchel Smith Synthesis of 13-alkyl-gon-4-ones
NL125069C (no) * 1963-12-24
FR1434172A (fr) 1963-12-24 1966-04-08 Ciba Geigy Procédé de préparation de nouvelles oestrones substituées
US4412993A (en) * 1980-01-25 1983-11-01 The Upjohn Company Method of treating pseudopregnancy, galactorrhea and mastitis in mammals
US4788218A (en) * 1984-05-21 1988-11-29 Sri International 17 a β-hydroxy-7 α-methyl-d-homo-19-norandrost-4,16-diene-3-one and the 17-esters thereof: methods of preparation and uses
JPS61502186A (ja) * 1984-05-21 1986-10-02 エス・ア−ル・アイ・インタ−ナシヨナル １７αβ−ヒドロキシ−７α−メチル−Ｄ−ホモ−１９−ノルアンドロスト−４，１６−ジエン−３−オンおよびその１７−エステル、ならびにその製法および使用
CZ293319B6 (cs) 1998-06-19 2004-04-14 Akzo Nobel N. V. Derivát testosteronu a farmaceutický prostředek s jeho obsahem
ATE228143T1 (de) 1999-03-08 2002-12-15 Akzo Nobel Nv 14.beta.,17-alpha-hydroxymethylandrostan derivate als androgene
ATE246703T1 (de) 1999-04-06 2003-08-15 Akzo Nobel Nv Oral wirksame 7-alpha-alkyl androgene
TW548277B (en) 1999-07-16 2003-08-21 Akzo Nobel Nv Orally active androgens

Also Published As

Publication number Publication date
MXPA06007195A (es) 2006-09-04
US20070155836A1 (en) 2007-07-05
AU2004303524A1 (en) 2005-07-07
KR20060123484A (ko) 2006-12-01
UA84037C2 (ru) 2008-09-10
DE602004009107D1 (de) 2007-10-31
IS8488A (is) 2006-05-26
BRPI0417781A (pt) 2007-03-20
CA2549148A1 (en) 2005-07-07
ES2294569T3 (es) 2008-04-01
US7582622B2 (en) 2009-09-01
WO2005061528A3 (en) 2005-09-09
DK1720895T3 (da) 2008-01-14
RU2357972C2 (ru) 2009-06-10
CN1898258B (zh) 2010-06-16
RU2006126632A (ru) 2008-01-27
CN1898258A (zh) 2007-01-17
HRP20070492T3 (en) 2007-12-31
NZ547772A (en) 2009-01-31
PL1720895T3 (pl) 2008-02-29
EP1720895A2 (en) 2006-11-15
WO2005061528A2 (en) 2005-07-07
ZA200604976B (en) 2007-04-25
PT1720895E (pt) 2007-10-09
TW200521134A (en) 2005-07-01
EP1720895B1 (en) 2007-09-19
JP2007515455A (ja) 2007-06-14
CY1106935T1 (el) 2012-09-26
ATE373674T1 (de) 2007-10-15
SI1720895T1 (sl) 2007-12-31
ECSP066666A (es) 2006-10-25
IL175890A0 (en) 2006-10-05
PE20050677A1 (es) 2005-10-04
DE602004009107T2 (de) 2008-06-19
AR046966A1 (es) 2006-01-04

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application