NO20060231L - Difenylureaderivater og deres anvendelse som kloridkanalblokkere - Google Patents

Difenylureaderivater og deres anvendelse som kloridkanalblokkere

Info

Publication number
NO20060231L
NO20060231L NO20060231A NO20060231A NO20060231L NO 20060231 L NO20060231 L NO 20060231L NO 20060231 A NO20060231 A NO 20060231A NO 20060231 A NO20060231 A NO 20060231A NO 20060231 L NO20060231 L NO 20060231L
Authority
NO
Norway
Prior art keywords
channel blockers
chloride channel
diphenylurea derivatives
derivatives
diphenylurea
Prior art date
Application number
NO20060231A
Other languages
English (en)
Inventor
Palle Christophersen
Bjarne H Dahl
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of NO20060231L publication Critical patent/NO20060231L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Den foreliggende oppfinnelse vedrører nye difenylureaderivater som kan anvendes som kloridkanalblokkere. Ved andre aspekter vedrører oppfinnelsen anvendelsen av disse forbindelsene ved en fremgangsmåte for terapi, og farmasøytiske preparater som omfatter forbindelsene ifølge oppfinnelsen.
NO20060231A 2003-06-17 2006-01-16 Difenylureaderivater og deres anvendelse som kloridkanalblokkere NO20060231L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200300898 2003-06-17
PCT/EP2004/051111 WO2004111017A1 (en) 2003-06-17 2004-06-15 Diphenylurea derivatives and their use as chloride channel blockers

Publications (1)

Publication Number Publication Date
NO20060231L true NO20060231L (no) 2006-01-16

Family

ID=33547538

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060231A NO20060231L (no) 2003-06-17 2006-01-16 Difenylureaderivater og deres anvendelse som kloridkanalblokkere

Country Status (20)

Country Link
US (1) US7691891B2 (no)
EP (1) EP1638948B1 (no)
JP (1) JP2006527735A (no)
KR (1) KR20060059901A (no)
CN (1) CN1805942B (no)
AT (1) ATE411301T1 (no)
AU (1) AU2004247429B2 (no)
BR (1) BRPI0410576A (no)
CA (1) CA2529806A1 (no)
DE (1) DE602004017175D1 (no)
DK (1) DK1638948T3 (no)
HK (1) HK1091816A1 (no)
IS (1) IS8211A (no)
MX (1) MXPA05013269A (no)
NO (1) NO20060231L (no)
NZ (1) NZ543595A (no)
RU (1) RU2350607C2 (no)
UA (1) UA81664C2 (no)
WO (1) WO2004111017A1 (no)
ZA (1) ZA200508828B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101287456A (zh) * 2004-12-17 2008-10-15 神经研究公司 用作钾通道激活剂的二苯基脲衍生物
KR20080103106A (ko) 2006-03-14 2008-11-26 뉴로서치 에이/에스 디페닐우레아 유도체 및 클로라이드 채널 차단제 또는 ＢＫＣａ 채널 조정자로서의 이의 용도
US20100292283A1 (en) * 2007-11-28 2010-11-18 Antonio Nardi Novel phenyl-acetamide and phenyl-propionamide derivatives useful as potassium channel modulators
US9834537B2 (en) 2013-11-27 2017-12-05 Korea Institute Of Science And Technology Compounds as chloride channel blocking agent
SI3622953T1 (sl) * 2016-05-17 2021-05-31 Scandion Oncology A/S Kombinirano zdravljenje raka
CN117229258B (zh) * 2022-06-07 2024-07-19 杭州壹瑞医药科技有限公司 N-四唑基芳基脲类衍生物及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4073489B2 (ja) * 1996-05-24 2008-04-09 ニューロサーチ・アクティーゼルスカブ 酸性基を有するフエニル誘導体、その製造方法及びそれをクロライドチャンネル遮断剤として使用する方法
TR199902593T2 (xx) * 1997-04-22 2000-03-21 Neurosearch A/S �kame edilmi� fenil t�revleri, bunlar�n haz�rlanmas� ve kullan�m�.
US6696475B2 (en) * 1997-04-22 2004-02-24 Neurosearch A/S Substituted phenyl derivatives, their preparation and use
AU5727899A (en) 1998-10-02 2000-04-26 Neurosearch A/S Diaminocyclobutene-3,4-dione derivatives, their preparation and use
BR9914638A (pt) 1998-10-22 2001-07-03 Neurosearch As Composto, método para a preparação do mesmo, composição farmacêutica, uso de um composto, e, método para o tratamento de um distúrbio ou doença de um corpo de animal vivo
AU2002223492A1 (en) * 2000-11-14 2002-05-27 Neurosearch A/S Use of malaria parasite anion channel blockers for treating malaria
US20050080112A1 (en) * 2001-06-22 2005-04-14 Madsen Lars Siim Compounds for use in disorders associated with mast cell or basophil acitvity
PL375318A1 (en) * 2002-08-01 2005-11-28 Neurosearch A/S Compounds useful for the treatment of diseases responsive to antiangiogenetic therapy
US20060160856A1 (en) * 2002-09-05 2006-07-20 Dahl Bjarne H Diarylurea derivatives and their use as chloride channel blockers
CN101287456A (zh) * 2004-12-17 2008-10-15 神经研究公司 用作钾通道激活剂的二苯基脲衍生物

Also Published As

Publication number Publication date
AU2004247429A1 (en) 2004-12-23
RU2005136532A (ru) 2006-07-27
WO2004111017A1 (en) 2004-12-23
ATE411301T1 (de) 2008-10-15
AU2004247429B2 (en) 2010-01-28
JP2006527735A (ja) 2006-12-07
DE602004017175D1 (de) 2008-11-27
US20060178413A1 (en) 2006-08-10
NZ543595A (en) 2009-01-31
RU2350607C2 (ru) 2009-03-27
DK1638948T3 (da) 2009-02-02
HK1091816A1 (en) 2007-01-26
IS8211A (is) 2005-12-30
KR20060059901A (ko) 2006-06-02
BRPI0410576A (pt) 2006-06-20
CN1805942A (zh) 2006-07-19
EP1638948A1 (en) 2006-03-29
US7691891B2 (en) 2010-04-06
EP1638948B1 (en) 2008-10-15
ZA200508828B (en) 2008-01-30
UA81664C2 (ru) 2008-01-25
MXPA05013269A (es) 2006-03-17
CN1805942B (zh) 2010-06-02
CA2529806A1 (en) 2004-12-23

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