NO20055206L - 4-(2-fenyloksyfenyl)-piperidin eller -1,2,3,6-tetrahydropyridinderivater som serotonin-reopptaksinhibitorer - Google Patents

4-(2-fenyloksyfenyl)-piperidin eller -1,2,3,6-tetrahydropyridinderivater som serotonin-reopptaksinhibitorer

Info

Publication number
NO20055206L
NO20055206L NO20055206A NO20055206A NO20055206L NO 20055206 L NO20055206 L NO 20055206L NO 20055206 A NO20055206 A NO 20055206A NO 20055206 A NO20055206 A NO 20055206A NO 20055206 L NO20055206 L NO 20055206L
Authority
NO
Norway
Prior art keywords
phenyloxyphenyl
piperidine
serotonin reuptake
reuptake inhibitors
disorder
Prior art date
Application number
NO20055206A
Other languages
English (en)
Norwegian (no)
Inventor
Jan Kehler
Benny Bang-Andersen
Friedrich Kroll
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO20055206L publication Critical patent/NO20055206L/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20055206A 2003-04-04 2005-11-04 4-(2-fenyloksyfenyl)-piperidin eller -1,2,3,6-tetrahydropyridinderivater som serotonin-reopptaksinhibitorer NO20055206L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46026503P 2003-04-04 2003-04-04
DKPA200300519 2003-04-04
PCT/DK2004/000241 WO2004087155A1 (en) 2003-04-04 2004-04-02 4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors

Publications (1)

Publication Number Publication Date
NO20055206L true NO20055206L (no) 2005-11-04

Family

ID=33132908

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055206A NO20055206L (no) 2003-04-04 2005-11-04 4-(2-fenyloksyfenyl)-piperidin eller -1,2,3,6-tetrahydropyridinderivater som serotonin-reopptaksinhibitorer

Country Status (18)

Country Link
US (1) US20060293360A1 (pt)
EP (1) EP1635828B1 (pt)
JP (1) JP2006522027A (pt)
AT (1) ATE392896T1 (pt)
AU (1) AU2004226837A1 (pt)
BR (1) BRPI0408320A (pt)
CO (1) CO5640133A2 (pt)
DE (1) DE602004013314T2 (pt)
DK (1) DK1635828T3 (pt)
ES (1) ES2303062T3 (pt)
HR (1) HRP20080262T3 (pt)
MX (1) MXPA05010627A (pt)
NO (1) NO20055206L (pt)
NZ (1) NZ540891A (pt)
PL (1) PL1635828T3 (pt)
PT (1) PT1635828E (pt)
SI (1) SI1635828T1 (pt)
WO (1) WO2004087155A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1626720E (pt) 2003-04-04 2008-11-10 Lundbeck & Co As H Derivados de 4-(2-fenilsulfanil-fenil)-piperidina como inibidores da recaptação da serotonina
AU2007260356B2 (en) 2006-06-16 2013-01-24 H. Lundbeck A/S Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
TWI432194B (zh) * 2007-03-20 2014-04-01 Lundbeck & Co As H 4-〔2-(4-甲基苯硫基)苯基〕哌啶之新穎治療用途
TWI396689B (zh) 2008-11-14 2013-05-21 Amgen Inc 作為磷酸二酯酶10抑制劑之吡衍生物
TW201030001A (en) 2008-11-14 2010-08-16 Amgen Inc Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors
PT2358674E (pt) 2008-11-14 2013-03-05 Theravance Inc Processo de preparação de compostos de 4-[2-(2-fluorofenoximetil)fenil]piperidina
MX2011006575A (es) 2008-12-17 2011-10-06 Amgen Inc Compuestos de aminopiridina y carboxipiridina como inhibidores de la fosfodiesterasa 10.
WO2011085291A1 (en) * 2010-01-11 2011-07-14 Theravance, Inc. 1 - (2 - phenoxymethylphenyl) piperazine compounds as serotonin and norepinephrine reuptake inhibitors
EP2550252B1 (en) * 2010-03-22 2015-05-06 Theravance Biopharma R&D IP, LLC 1-(2-phenoxymethylheteroaryl)piperidine and piperazine compounds
ES2532204T3 (es) * 2010-04-22 2015-03-25 Theravance Biopharma R&D Ip, Llc Combinación de un inhibidor de la recaptación de serotonina y norepinefrina y un agonista opioide para el tratamiento de dolor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4241071A (en) * 1977-01-27 1980-12-23 American Hoechst Corporation Antidepressant (α-phenyl-2-tolyl)azacycloalkanes
US4198417A (en) * 1979-01-10 1980-04-15 American Hoechst Corporation Phenoxyphenylpiperidines
TR200102478T2 (tr) * 1999-02-23 2002-03-21 Pfizer Products Inc. CNS bozukluklarìnìn tedavisi i‡in monoamin yeniden alìm inhibit”rleri.
OA12062A (en) * 1999-10-13 2006-05-03 Pfizer Prod Inc Biaryl ether derivatives useful as monoamine reuptake inhibitors.
UA81749C2 (uk) * 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну

Also Published As

Publication number Publication date
PT1635828E (pt) 2008-07-01
PL1635828T3 (pl) 2008-10-31
CO5640133A2 (es) 2006-05-31
AU2004226837A1 (en) 2004-10-14
JP2006522027A (ja) 2006-09-28
DK1635828T3 (da) 2008-08-11
EP1635828A1 (en) 2006-03-22
ATE392896T1 (de) 2008-05-15
NZ540891A (en) 2008-07-31
SI1635828T1 (sl) 2008-08-31
US20060293360A1 (en) 2006-12-28
BRPI0408320A (pt) 2006-03-07
DE602004013314T2 (de) 2008-08-07
ES2303062T3 (es) 2008-08-01
DE602004013314D1 (de) 2008-06-05
MXPA05010627A (es) 2005-12-12
EP1635828B1 (en) 2008-04-23
HRP20080262T3 (en) 2009-04-30
WO2004087155A1 (en) 2004-10-14

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Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104