NO20053588L - Acylaminotiazol-derivater, fremstilling og anvendelse derav som beta-amyloidpeptid-produksjonsinhibitorer. - Google Patents

Acylaminotiazol-derivater, fremstilling og anvendelse derav som beta-amyloidpeptid-produksjonsinhibitorer.

Info

Publication number
NO20053588L
NO20053588L NO20053588A NO20053588A NO20053588L NO 20053588 L NO20053588 L NO 20053588L NO 20053588 A NO20053588 A NO 20053588A NO 20053588 A NO20053588 A NO 20053588A NO 20053588 L NO20053588 L NO 20053588L
Authority
NO
Norway
Prior art keywords
beta
preparation
amyloid peptide
peptide production
production inhibitors
Prior art date
Application number
NO20053588A
Other languages
English (en)
Other versions
NO20053588D0 (no
NO330415B1 (no
Inventor
Viviane Van Dorsselaer
Pierre Despeyroux
Daniel Frehel
Bruno Schoentjes
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of NO20053588D0 publication Critical patent/NO20053588D0/no
Publication of NO20053588L publication Critical patent/NO20053588L/no
Publication of NO330415B1 publication Critical patent/NO330415B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20053588A 2003-01-23 2005-07-22 Acylaminotiazol-derivater, fremgangsmate for fremstilling derav, anvendelse derav som beta-amyloidpeptid-produksjonsinhibitorer og farmasoytisk sammemsetning inneholdende de samme NO330415B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0300703A FR2850380B1 (fr) 2003-01-23 2003-01-23 Derives d'acylaminothiazole, leur preparation et leur utilisation en therapeutique
PCT/FR2004/000140 WO2004067520A1 (fr) 2003-01-23 2004-01-22 Derives d'acylaminothiazole, leur preparation et leur utilisation en tant qu’inhibiteurs de la production du peptide beta-amyloide

Publications (3)

Publication Number Publication Date
NO20053588D0 NO20053588D0 (no) 2005-07-22
NO20053588L true NO20053588L (no) 2005-09-22
NO330415B1 NO330415B1 (no) 2011-04-11

Family

ID=32669150

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053588A NO330415B1 (no) 2003-01-23 2005-07-22 Acylaminotiazol-derivater, fremgangsmate for fremstilling derav, anvendelse derav som beta-amyloidpeptid-produksjonsinhibitorer og farmasoytisk sammemsetning inneholdende de samme

Country Status (24)

Country Link
US (2) US7563903B2 (no)
EP (1) EP1590337B1 (no)
JP (1) JP2006515888A (no)
KR (1) KR101059669B1 (no)
CN (1) CN100532370C (no)
AR (1) AR042745A1 (no)
AT (1) ATE404545T1 (no)
AU (1) AU2004207658B2 (no)
BR (1) BRPI0406893A (no)
CA (1) CA2511610A1 (no)
DE (1) DE602004015726D1 (no)
FR (1) FR2850380B1 (no)
HR (1) HRP20050637A2 (no)
IL (1) IL169428A (no)
MA (1) MA27610A1 (no)
ME (1) MEP16708A (no)
MX (1) MXPA05007847A (no)
NO (1) NO330415B1 (no)
NZ (1) NZ541147A (no)
PL (1) PL377999A1 (no)
RS (1) RS51168B (no)
RU (1) RU2360907C2 (no)
TW (1) TWI320710B (no)
WO (1) WO2004067520A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1633350B1 (en) * 2003-06-05 2012-10-03 Elan Pharmaceuticals, Inc. Acylated amino acid amidyl pyrazoles and related compounds
US7514566B2 (en) * 2006-01-18 2009-04-07 Amgen, Inc. Thiazole compounds and methods of use
CA2693473A1 (en) * 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of pkb
EP2173728A2 (en) 2007-07-17 2010-04-14 Amgen Inc. Heterocyclic modulators of pkb
US8668863B2 (en) 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
EP2371421A1 (en) * 2010-03-04 2011-10-05 Université de Lille 2 Droit et Santé Ligands of insulin degrading enzyme and their uses
EP2508511A1 (en) * 2011-04-07 2012-10-10 Laboratoire Biodim Inhibitors of viral replication, their process of preparation and their therapeutical uses
CN103145692B (zh) * 2013-03-12 2014-07-16 盐城工学院 一种4,5-二氢-6H-环戊烷并[b]噻吩-6-酮的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU729133B2 (en) 1996-11-22 2001-01-25 Elan Pharmaceuticals, Inc. N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
EA002100B1 (ru) * 1996-12-23 2001-12-24 Элан Фармасьютикалз, Инк. ЦИКЛОАЛКИЛЬНЫЕ СОЕДИНЕНИЯ, ЛАКТАМЫ, ЛАКТОНЫ И РОДСТВЕННЫЕ СОЕДИНЕНИЯ, СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ И СПОСОБЫ ИНГИБИРОВАНИЯ ВЫСВОБОЖДЕНИЯ И/ИЛИ СИНТЕЗА β-АМИЛОИДНОГО ПЕПТИДА С ПОМОЩЬЮ УКАЗАННЫХ СОЕДИНЕНИЙ
ATE288904T1 (de) * 1998-06-18 2005-02-15 Bristol Myers Squibb Co Durch kohlenstoff substituierte aminothiazole als inhibitoren von zyclin-abhägigen kinasen
AU6229699A (en) * 1998-10-26 2000-05-15 Sumitomo Pharmaceuticals Company, Limited Beta-amyloid formation inhibitors
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
AR039059A1 (es) * 2001-08-06 2005-02-09 Sanofi Aventis Compuesto derivado de acilaminotiazol, su utilizacion, procedimientos para prepararlo, composicion farmaceutica que lo comprende, y compuestos intermediarios

Also Published As

Publication number Publication date
NZ541147A (en) 2008-06-30
PL377999A1 (pl) 2006-02-20
WO2004067520A1 (fr) 2004-08-12
IL169428A (en) 2010-12-30
NO20053588D0 (no) 2005-07-22
KR20050094039A (ko) 2005-09-26
US7879889B2 (en) 2011-02-01
BRPI0406893A (pt) 2006-01-03
CN1777593A (zh) 2006-05-24
CN100532370C (zh) 2009-08-26
CA2511610A1 (en) 2004-08-12
EP1590337B1 (fr) 2008-08-13
DE602004015726D1 (de) 2008-09-25
US7563903B2 (en) 2009-07-21
HRP20050637A2 (en) 2005-10-31
US20090253753A1 (en) 2009-10-08
US20060052426A1 (en) 2006-03-09
NO330415B1 (no) 2011-04-11
AU2004207658B2 (en) 2009-10-29
KR101059669B1 (ko) 2011-08-25
ATE404545T1 (de) 2008-08-15
AR042745A1 (es) 2005-06-29
AU2004207658A1 (en) 2004-08-12
RU2005126608A (ru) 2006-04-27
JP2006515888A (ja) 2006-06-08
RU2360907C2 (ru) 2009-07-10
MXPA05007847A (es) 2006-05-17
RS51168B (sr) 2010-10-31
FR2850380A1 (fr) 2004-07-30
RS20050563A (en) 2007-06-04
TWI320710B (en) 2010-02-21
FR2850380B1 (fr) 2006-07-07
MA27610A1 (fr) 2005-11-01
MEP16708A (en) 2010-06-10
EP1590337A1 (fr) 2005-11-02
TW200503699A (en) 2005-02-01

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