NO20052598L - Nye 2,3-dihydro-4(1H)-pyridonforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem. - Google Patents

Nye 2,3-dihydro-4(1H)-pyridonforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem.

Info

Publication number
NO20052598L
NO20052598L NO20052598A NO20052598A NO20052598L NO 20052598 L NO20052598 L NO 20052598L NO 20052598 A NO20052598 A NO 20052598A NO 20052598 A NO20052598 A NO 20052598A NO 20052598 L NO20052598 L NO 20052598L
Authority
NO
Norway
Prior art keywords
branched
linear
group
dihydro
aryl
Prior art date
Application number
NO20052598A
Other languages
English (en)
Other versions
NO20052598D0 (no
Inventor
Sylvain Rault
Pierre Renard
Patrick Dallemagne
Brian Lockhart
Pierre Lestage
Bruno Pfeiffer
Laurence Danober
Nicolas Leflemme
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of NO20052598L publication Critical patent/NO20052598L/no
Publication of NO20052598D0 publication Critical patent/NO20052598D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Forbindelser med formel (I): hvori: * R1 representerer et hydrogenatom eller en aryl(C1-C6)alkylgruppe hvor alkylenheten kan være lineær eller forgrenet, en lineær eller forgrenet (C1-C6)alkylgruppe, en lineær eller forgrenet (C1-C6)acylgruppe, en lineær eller forgrenet (C1-C6)alkoksykarbonylgruppe, en aryl(C1-C6)alkoksykarbonylgruppe hvori alkoksyenheten kan være lineær eller forgrenet, eller en trifluoracetylgruppe, * R2 representerer et hydrogenatom eller en lineær eller forgrenet (C1-C6)alkylgruppe, * X representerer et oksygenatom eller NOR3, * R3 representerer et hydrogenatom eller en lineær eller forgrenet (C1-C6)alkylgruppe eventuelt substituert med én eller flere identiske eller forskjellige grupper valgt fra hydroksy, amino (eventuelt substituert med én eller to lineære eller forgrenede (C1-C6)alkylgrupper og lineær eller forgrenet (C1-C6)alkoksy, * Ar representerer en arylgruppe eller en heteroarylgruppe, deres isomerer og addisjonssalter derav med en farmasøytisk akseptabel syre. Medikamenter.
NO20052598A 2002-11-05 2005-05-30 Nye 2,3-dihydro-4(1H)-pyridonforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem. NO20052598D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0213803A FR2846654A1 (fr) 2002-11-05 2002-11-05 Nouveaux derives de la 2,3-dihydro-4(1h)-pyridinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2003/003276 WO2004043952A1 (fr) 2002-11-05 2003-11-04 Nouveaux derives de 2,3-dihydro-4(1h)-pyridinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
NO20052598L true NO20052598L (no) 2005-05-30
NO20052598D0 NO20052598D0 (no) 2005-05-30

Family

ID=32104441

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052598A NO20052598D0 (no) 2002-11-05 2005-05-30 Nye 2,3-dihydro-4(1H)-pyridonforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem.

Country Status (16)

Country Link
US (1) US20060019995A1 (no)
EP (1) EP1560825A1 (no)
JP (1) JP2006508110A (no)
KR (1) KR20050084942A (no)
CN (1) CN1705660A (no)
AR (1) AR041758A1 (no)
AU (1) AU2003292322A1 (no)
BR (1) BR0315996A (no)
CA (1) CA2503993A1 (no)
EA (1) EA200500716A1 (no)
FR (1) FR2846654A1 (no)
MA (1) MA27407A1 (no)
MX (1) MXPA05004793A (no)
NO (1) NO20052598D0 (no)
PL (1) PL375959A1 (no)
WO (1) WO2004043952A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009330194B2 (en) 2008-12-22 2015-07-09 Chemocentryx, Inc. C5aR antagonists
PT2585064T (pt) 2010-06-24 2017-08-08 Chemocentryx Inc Antagonistas do c5ar
FR3004107A1 (fr) * 2013-04-08 2014-10-10 Univ Rennes Composes photoprotecteurs, compositions les comprenant, et leurs utilisations
CN104109113B (zh) * 2013-04-17 2016-01-27 中国科学院化学研究所 多取代二氢吡啶-4-酮类化合物及其制备方法与应用
NZ730123A (en) 2014-09-29 2023-05-26 Chemocentryx Inc Processes and intermediates in the preparation of c5ar antagonists
NZ744083A (en) 2016-01-14 2022-07-01 Chemocentryx Inc Method of treating c3 glomerulopathy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2013761A1 (en) * 1970-03-21 1971-10-07 Farbwerke Hoechst AG, vorm. Meister Lucius & Brüning, 6000 Frankfurt 4-azacycloalk-2-enone prepn
FR2793246B1 (fr) * 1999-05-03 2001-06-29 Adir Nouveaux derives de 1-aza-2-alkyl-6-aryl-cycloalcanes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
MXPA05004793A (es) 2005-07-22
FR2846654A1 (fr) 2004-05-07
AU2003292322A1 (en) 2004-06-03
EP1560825A1 (fr) 2005-08-10
JP2006508110A (ja) 2006-03-09
AR041758A1 (es) 2005-05-26
CA2503993A1 (fr) 2004-05-27
EA200500716A1 (ru) 2005-10-27
BR0315996A (pt) 2005-09-27
MA27407A1 (fr) 2005-06-01
PL375959A1 (en) 2005-12-12
WO2004043952A1 (fr) 2004-05-27
CN1705660A (zh) 2005-12-07
NO20052598D0 (no) 2005-05-30
US20060019995A1 (en) 2006-01-26
KR20050084942A (ko) 2005-08-29

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