NO20052422L - Stabiliserte, fast tilstand polypeptidpartikler. - Google Patents
Stabiliserte, fast tilstand polypeptidpartikler.Info
- Publication number
- NO20052422L NO20052422L NO20052422A NO20052422A NO20052422L NO 20052422 L NO20052422 L NO 20052422L NO 20052422 A NO20052422 A NO 20052422A NO 20052422 A NO20052422 A NO 20052422A NO 20052422 L NO20052422 L NO 20052422L
- Authority
- NO
- Norway
- Prior art keywords
- polypeptide
- polypeptide particles
- particles
- stabilizing
- solid state
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 239000002245 particle Substances 0.000 title abstract 5
- 239000007787 solid Substances 0.000 title abstract 2
- 230000000087 stabilizing effect Effects 0.000 abstract 4
- 230000015556 catabolic process Effects 0.000 abstract 2
- 238000006731 degradation reaction Methods 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 230000000996 additive effect Effects 0.000 abstract 1
- 230000004962 physiological condition Effects 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42228902P | 2002-10-29 | 2002-10-29 | |
| PCT/US2003/034229 WO2004039392A2 (en) | 2002-10-29 | 2003-10-28 | Stabilized, solid-state polypeptide particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20052422D0 NO20052422D0 (no) | 2005-05-19 |
| NO20052422L true NO20052422L (no) | 2005-07-20 |
Family
ID=32230336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20052422A NO20052422L (no) | 2002-10-29 | 2005-05-19 | Stabiliserte, fast tilstand polypeptidpartikler. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20060198894A1 (es) |
| EP (1) | EP1562626B1 (es) |
| JP (1) | JP2006504772A (es) |
| KR (1) | KR20050083841A (es) |
| CN (1) | CN1708314A (es) |
| AU (1) | AU2003285075B2 (es) |
| BR (1) | BR0315782A (es) |
| CA (1) | CA2502378A1 (es) |
| DE (1) | DE60317822D1 (es) |
| EC (1) | ECSP055822A (es) |
| IL (1) | IL168106A0 (es) |
| MX (1) | MXPA05004593A (es) |
| MY (1) | MY138608A (es) |
| NO (1) | NO20052422L (es) |
| NZ (2) | NZ562480A (es) |
| PL (1) | PL376219A1 (es) |
| RU (1) | RU2329823C2 (es) |
| TW (1) | TW200505497A (es) |
| WO (1) | WO2004039392A2 (es) |
| ZA (1) | ZA200504311B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2264065B1 (en) | 2003-08-05 | 2017-03-08 | Novo Nordisk A/S | Novel insulin derivatives |
| US20190330295A1 (en) * | 2005-05-04 | 2019-10-31 | Zealand Pharma A/S | Glucagon-like-peptide-2 (glp-2) analogues |
| CN101389650B (zh) | 2005-12-28 | 2012-10-10 | 诺沃-诺迪斯克有限公司 | 包含酰化胰岛素和锌的组合物以及制备所述组合物的方法 |
| JP4847775B2 (ja) * | 2006-03-29 | 2011-12-28 | シーシーアイ株式会社 | 安定なポリオール脱水素酵素組成物 |
| JP5552046B2 (ja) | 2007-06-13 | 2014-07-16 | ノボ・ノルデイスク・エー／エス | インスリン誘導体を含有する薬学的製剤 |
| US9603904B2 (en) | 2008-10-30 | 2017-03-28 | Novo Nordisk A/S | Treating diabetes melitus using insulin injections with less than daily injection frequency |
| RS59978B1 (sr) | 2010-08-11 | 2020-03-31 | Ironwood Pharmaceuticals Inc | Stabilne formulacije linaklotida |
| RU2013123515A (ru) | 2010-10-27 | 2014-12-10 | Ново Нордиск А/С | Лечение сахарного диабета с помощью инъекций инсулина, вводимых с различными интервалами |
| EP2991672A1 (en) | 2013-04-30 | 2016-03-09 | Novo Nordisk A/S | Novel administration regime |
| US10335464B1 (en) | 2018-06-26 | 2019-07-02 | Novo Nordisk A/S | Device for titrating basal insulin |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816440A (en) * | 1985-09-26 | 1989-03-28 | Cetus Corporation | Stable formulation of biologically active proteins for parenteral injection |
| US4806343A (en) * | 1986-03-13 | 1989-02-21 | University Of Southwestern Louisiana | Cryogenic protectant for proteins |
| JPH02218618A (ja) * | 1989-02-21 | 1990-08-31 | Green Cross Corp:The | トロンビン粉末製剤 |
| US5128242A (en) * | 1989-06-19 | 1992-07-07 | The Administrators Of The Tulane Educational Fund | Hypothalamic polypeptides with adenylate cyclase stimulating activity |
| ES2087323T3 (es) * | 1991-02-19 | 1996-07-16 | Takeda Chemical Industries Ltd | Metodo para producir peptidos exentos de cisteina. |
| JP3356816B2 (ja) * | 1992-03-24 | 2002-12-16 | セイコーインスツルメンツ株式会社 | 半導体光電気変換装置 |
| JPH083056A (ja) * | 1994-06-17 | 1996-01-09 | Nippon Kayaku Co Ltd | 末梢神経障害の軽減剤 |
| JPH08131171A (ja) * | 1994-11-11 | 1996-05-28 | Asahi Chem Ind Co Ltd | 逆転写酵素の安定化組成物 |
| US6267958B1 (en) * | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| US6156331A (en) * | 1996-02-02 | 2000-12-05 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
| PT1238659E (pt) * | 1996-02-02 | 2005-01-31 | Alza Corp | Libertacao sustentada de um agente activo utilizando um sistema implantavel |
| US6395292B2 (en) * | 1996-02-02 | 2002-05-28 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
| US5763401A (en) * | 1996-07-12 | 1998-06-09 | Bayer Corporation | Stabilized albumin-free recombinant factor VIII preparation having a low sugar content |
| EP0959873B1 (en) * | 1996-12-20 | 2006-03-01 | ALZA Corporation | Gel composition and methods |
| ID22933A (id) * | 1997-04-28 | 1999-12-16 | Lilly Co Eli | Fomulasi protien c terakivasi |
| JP4156688B2 (ja) * | 1997-07-22 | 2008-09-24 | アルフレッサファーマ株式会社 | 安定なヘモグロビン含有組成物 |
| PT1041975E (pt) * | 1997-12-22 | 2003-01-31 | Alza Corp | Membranas de controlo de taxa para dispositivos de fornecimento controlado de drogas |
| ES2378675T3 (es) * | 1997-12-30 | 2012-04-16 | Intarcia Therapeutics, Inc | Sistema de suministro de un agente beneficioso con una membrana obturadora |
| DE60034445T2 (de) * | 1999-05-31 | 2008-01-03 | Mitsubishi Chemical Corp. | Gefriergetrocknete hgf-präparationen |
| AU2003219787A1 (en) * | 2002-02-14 | 2003-09-04 | Bayer Pharmaceuticals Corporation | Formulation strategies in stabilizing peptides in organic solvents and in dried states |
| GB0207092D0 (en) * | 2002-03-26 | 2002-05-08 | Sod Conseils Rech Applic | Stable pharmaceutical composition containing factor VIII |
-
2003
- 2003-10-28 RU RU2005116250/15A patent/RU2329823C2/ru not_active IP Right Cessation
- 2003-10-28 KR KR1020057007327A patent/KR20050083841A/ko not_active Application Discontinuation
- 2003-10-28 CA CA002502378A patent/CA2502378A1/en not_active Abandoned
- 2003-10-28 AU AU2003285075A patent/AU2003285075B2/en not_active Ceased
- 2003-10-28 NZ NZ562480A patent/NZ562480A/en not_active IP Right Cessation
- 2003-10-28 BR BR0315782-2A patent/BR0315782A/pt not_active IP Right Cessation
- 2003-10-28 WO PCT/US2003/034229 patent/WO2004039392A2/en active IP Right Grant
- 2003-10-28 EP EP03779390A patent/EP1562626B1/en not_active Expired - Lifetime
- 2003-10-28 US US10/696,405 patent/US20060198894A1/en not_active Abandoned
- 2003-10-28 MX MXPA05004593A patent/MXPA05004593A/es active IP Right Grant
- 2003-10-28 NZ NZ539811A patent/NZ539811A/en unknown
- 2003-10-28 DE DE60317822T patent/DE60317822D1/de not_active Expired - Lifetime
- 2003-10-28 JP JP2004548544A patent/JP2006504772A/ja active Pending
- 2003-10-28 CN CNA2003801023848A patent/CN1708314A/zh active Pending
- 2003-10-28 PL PL03376219A patent/PL376219A1/xx not_active Application Discontinuation
- 2003-10-29 TW TW092129977A patent/TW200505497A/zh unknown
- 2003-10-29 MY MYPI20034115A patent/MY138608A/en unknown
-
2005
- 2005-04-18 IL IL168106A patent/IL168106A0/en unknown
- 2005-05-19 NO NO20052422A patent/NO20052422L/no not_active Application Discontinuation
- 2005-05-26 ZA ZA200504311A patent/ZA200504311B/en unknown
- 2005-05-30 EC EC2005005822A patent/ECSP055822A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA05004593A (es) | 2005-07-26 |
| RU2329823C2 (ru) | 2008-07-27 |
| US20060198894A1 (en) | 2006-09-07 |
| JP2006504772A (ja) | 2006-02-09 |
| NZ539811A (en) | 2008-08-29 |
| MY138608A (en) | 2009-07-31 |
| PL376219A1 (en) | 2005-12-27 |
| AU2003285075B2 (en) | 2009-10-29 |
| RU2005116250A (ru) | 2006-01-20 |
| DE60317822D1 (de) | 2008-01-10 |
| AU2003285075A1 (en) | 2004-05-25 |
| NO20052422D0 (no) | 2005-05-19 |
| TW200505497A (en) | 2005-02-16 |
| ZA200504311B (en) | 2006-07-26 |
| EP1562626A2 (en) | 2005-08-17 |
| WO2004039392A3 (en) | 2004-09-30 |
| KR20050083841A (ko) | 2005-08-26 |
| BR0315782A (pt) | 2005-09-20 |
| IL168106A0 (en) | 2009-02-11 |
| WO2004039392A2 (en) | 2004-05-13 |
| CA2502378A1 (en) | 2004-05-13 |
| NZ562480A (en) | 2009-08-28 |
| CN1708314A (zh) | 2005-12-14 |
| EP1562626B1 (en) | 2007-11-28 |
| ECSP055822A (es) | 2005-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |