NO20050270L - Nye forbindelser, deres anvendelse og fremstilling - Google Patents
Nye forbindelser, deres anvendelse og fremstillingInfo
- Publication number
- NO20050270L NO20050270L NO20050270A NO20050270A NO20050270L NO 20050270 L NO20050270 L NO 20050270L NO 20050270 A NO20050270 A NO 20050270A NO 20050270 A NO20050270 A NO 20050270A NO 20050270 L NO20050270 L NO 20050270L
- Authority
- NO
- Norway
- Prior art keywords
- manufacture
- new compounds
- compounds
- relates
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Abstract
Foreliggende oppfinnelse angår forbindelser med generell formel (I) Forbindelsene kan fremstilles ved i og for seg kjente fremgangsmåter og kan anvendes for å behandle et menneske- eller dyresubjekt som lider av en serotoninrelatert forstyrrelse. Oppfinnelsen angår også anvendelse av slike, så vel som farmasøytiske sammensetninger som innbefatter en forbindelse med formel (I).
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0201881A SE0201881D0 (sv) | 2002-06-19 | 2002-06-19 | Novel compounds, their use, and preparation |
US40611902P | 2002-08-26 | 2002-08-26 | |
SE0202516A SE0202516D0 (sv) | 2002-08-26 | 2002-08-26 | Novel compounds, their use, and preparation |
US41670102P | 2002-10-07 | 2002-10-07 | |
PCT/SE2003/001044 WO2004000830A1 (en) | 2002-06-19 | 2003-06-18 | Novel compounds, their use and preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20050270L true NO20050270L (no) | 2005-01-17 |
Family
ID=30003921
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20050270A NO20050270L (no) | 2002-06-19 | 2005-01-17 | Nye forbindelser, deres anvendelse og fremstilling |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1513831B1 (no) |
JP (1) | JP4460450B2 (no) |
CN (1) | CN100484933C (no) |
AT (1) | ATE454383T1 (no) |
AU (1) | AU2003243089B2 (no) |
BR (1) | BR0311970A (no) |
CA (1) | CA2485537A1 (no) |
DE (1) | DE60330864D1 (no) |
EA (1) | EA008148B1 (no) |
HK (1) | HK1079526A1 (no) |
IL (1) | IL165220A0 (no) |
MX (1) | MXPA04012711A (no) |
NO (1) | NO20050270L (no) |
NZ (1) | NZ536664A (no) |
WO (1) | WO2004000830A1 (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CL2004000826A1 (es) | 2003-04-25 | 2005-03-04 | Pfizer | Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129 |
JP5173190B2 (ja) | 2004-08-25 | 2013-03-27 | 武田薬品工業株式会社 | 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法 |
EP2018863B9 (en) | 2006-05-16 | 2015-02-18 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound and use thereof |
US9820861B2 (en) | 2007-10-09 | 2017-11-21 | Richard Charles Smith | Rail-fixing implant |
US20100266504A1 (en) | 2007-11-15 | 2010-10-21 | Takahiro Matsumoto | Condensed pyridine derivative and use thereof |
MY157497A (en) | 2009-06-15 | 2016-06-15 | Takeda Pharmaceutical | Pyrazinooxazepine derivatives |
EP2510949A4 (en) | 2009-12-11 | 2013-11-13 | Astellas Pharma Inc | THERAPEUTICS FOR FIBROMYALGIA |
US20130267500A1 (en) | 2010-09-01 | 2013-10-10 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level |
US9126986B2 (en) | 2011-12-28 | 2015-09-08 | Janssen Sciences Ireland Uc | Hetero-bicyclic derivatives as HCV inhibitors |
WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
US20210052600A1 (en) | 2017-12-27 | 2021-02-25 | Takeda Pharmaceutical Company Limited | Therapeutic agents for stress urinary incontinence and incotinence of feces |
Family Cites Families (50)
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US3253989A (en) | 1963-02-11 | 1966-05-31 | American Cyanamid Co | Process for producing anorexia |
GB1457400A (en) | 1972-11-20 | 1976-12-01 | Pfizer | Pharmaceutical compositions containing 2-substituted quinoxa lines |
AR207133A1 (es) | 1973-02-20 | 1976-09-15 | Ciba Geigy Ag | Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino-propano |
FI193974A (no) | 1973-07-13 | 1975-01-14 | Merck & Co Inc | |
US4081542A (en) | 1975-04-21 | 1978-03-28 | Merck & Co., Inc. | Piperazinylpyrazines |
EP0572863A1 (de) | 1992-06-05 | 1993-12-08 | F. Hoffmann-La Roche Ag | ZNS Pyrazinoindole |
GB9313913D0 (en) | 1993-07-06 | 1993-08-18 | Smithkline Beecham Plc | Novel compounds |
TW334423B (en) | 1993-10-22 | 1998-06-21 | Hoffmann La Roche | Tricyclic 1-aminoethylpyrrole-derivatives |
TW270114B (no) | 1993-10-22 | 1996-02-11 | Hoffmann La Roche | |
FR2722788B1 (fr) | 1994-07-20 | 1996-10-04 | Pf Medicament | Nouvelles piperazides derivees d'aryl piperazine, leurs procedes de preparation, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant |
KR100232341B1 (ko) | 1994-10-13 | 2000-07-01 | 디. 제이. 우드 | 류코트리엔 b4(ltb4) 길항물질로서의 벤조피란 및 벤조-축합된 화합물 |
US5688795A (en) | 1994-11-08 | 1997-11-18 | Syntex (U.S.A.) Inc. | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists |
FR2740134B1 (fr) | 1995-10-18 | 1998-01-09 | Pf Medicament | Derives d'amines cycliques d'aryl-piperazines, leur preparation et les compositions pharmaceutiques les contenant |
AU5343298A (en) | 1997-01-13 | 1998-08-03 | Yamanouchi Pharmaceutical Co., Ltd. | 5-ht2c receptor agonists and aminoalkylindazole derivatives |
WO1998033504A1 (en) | 1997-02-03 | 1998-08-06 | Akzo Nobel N.V. | Treatment of urinary incontinence |
EP0863136B1 (en) | 1997-02-25 | 2003-09-24 | Akzo Nobel N.V. | Derivatives of azetidine and pyrrolidine |
FR2761064B1 (fr) | 1997-03-20 | 1999-06-04 | Pf Medicament | Piperazines derivees d'amines cycliques, leur preparation et leur application comme medicaments |
AU727654B2 (en) | 1997-06-13 | 2000-12-21 | Yamanouchi Pharmaceutical Co., Ltd. | Tricyclic pyrazole derivative |
AU8130298A (en) | 1997-07-15 | 1999-02-10 | Sankyo Company Limited | Piperazine derivatives |
WO1999058490A2 (en) | 1998-05-08 | 1999-11-18 | Akzo Nobel N.V. | Novel aryl-hydro naphthalenal kanamines |
GB9819019D0 (en) | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds II |
GB9819020D0 (en) | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds III |
GB9819033D0 (en) | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds VI |
GB9819035D0 (en) | 1998-09-01 | 1998-10-28 | Cerebrus Res Ltd | Chemical compounds VII |
GB9819032D0 (en) | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds IV |
GB9820767D0 (en) | 1998-09-23 | 1998-11-18 | Cerebrus Ltd | Chemical compounds VIII |
EA200100671A1 (ru) | 1998-12-17 | 2001-12-24 | Американ Хоум Продактс Корпорейшн | ПРОИЗВОДНЫЕ 2,3,4,4a-ТЕТРАГИДРО-1H-ПИРАЗИНО [1,2a]ХИНОКСАЛИН-5(6H)-ОНА, ЯВЛЯЮЩИЕСЯ АГОНИСТАМИ 5HT2C |
US6372745B1 (en) | 1999-12-06 | 2002-04-16 | American Home Products Corporation | 2,3,4,4A-tetrahydro-1H-pyrazino[1,2-A]quinoxalin-5(6H)one derivatives |
AU2619800A (en) | 1999-01-27 | 2000-08-18 | Eli Lilly And Company | Aminoalkylbenzofurans as serotonin (5-ht(2c)) agonists |
GB9902047D0 (en) | 1999-01-29 | 1999-03-17 | Cerebrus Ltd | Chemical compounds XI |
DE60024986T2 (de) * | 1999-05-21 | 2006-07-27 | Biovitrum Ab | Pyrazinyl-piperazin-verbindungen, ihre anwendung und herstellung |
US6552017B1 (en) | 1999-06-15 | 2003-04-22 | Bristol-Myers Squibb Pharma Company | Substituted heterocycle fused gamma-carbolines |
US6967201B1 (en) | 1999-07-29 | 2005-11-22 | Eli Lilly And Company | Benzofurylpiperazines and benzofurylhomopiperazines: serotonin agonists |
JP2003506369A (ja) | 1999-07-29 | 2003-02-18 | イーライ・リリー・アンド・カンパニー | セロトニン作動性のベンゾフラン |
CA2378879A1 (en) | 1999-07-29 | 2001-02-08 | Yao-Chang Xu | Serotonergic benzothiophenes |
DK1204658T3 (da) | 1999-07-29 | 2003-09-01 | Lilly Co Eli | Benzofurylpiperazin-serotoninagonister |
GB9918965D0 (en) | 1999-08-11 | 1999-10-13 | Cerebrus Ltd | Chemical compounds xxi |
GB9918962D0 (en) | 1999-08-11 | 1999-10-13 | Cerebrus Ltd | Chemical compounds xxii |
EP1132389A1 (en) | 2000-03-06 | 2001-09-12 | Vernalis Research Limited | New aza-indolyl derivatives for the treatment of obesity |
AU2001283955B2 (en) | 2000-07-31 | 2006-05-18 | F. Hoffmann-La Roche Ag | Piperazine derivatives |
WO2002019998A2 (en) | 2000-09-08 | 2002-03-14 | Eli Lilly And Company | A method of treating weight gain associated with atypical antipsychotic use |
CN100334076C (zh) | 2000-10-16 | 2007-08-29 | 霍夫曼-拉罗奇有限公司 | 二氢吲哚衍生物及其作为5-ht2受体配体的用途 |
EP1330457B1 (en) | 2000-11-03 | 2004-10-20 | Wyeth | Cyclopenta[b][1,4] diazepino[6,7,1-hi]indoles as 5ht2c antagonists |
AU2002227170A1 (en) | 2000-11-03 | 2002-05-15 | Wyeth | Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives |
PL360982A1 (en) * | 2000-11-20 | 2004-09-20 | Biovitrum Ab | Piperazinylpyrazines compounds as antagonists of serotonin 5-ht2 receptor |
NZ525700A (en) * | 2000-11-20 | 2004-12-24 | Biovitrum Ab | Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5HT-2 receptor |
GB0030710D0 (en) | 2000-12-15 | 2001-01-31 | Hoffmann La Roche | Piperazine derivatives |
CA2432085C (en) | 2000-12-27 | 2009-02-24 | F. Hoffmann-La Roche Ag | Indole derivatives and their use as 5-ht2b and 5-ht2c receptor ligands |
GB0106177D0 (en) | 2001-03-13 | 2001-05-02 | Hoffmann La Roche | Piperazine derivatives |
US6825198B2 (en) | 2001-06-21 | 2004-11-30 | Pfizer Inc | 5-HT receptor ligands and uses thereof |
-
2003
- 2003-06-18 CA CA002485537A patent/CA2485537A1/en not_active Abandoned
- 2003-06-18 JP JP2004530935A patent/JP4460450B2/ja not_active Expired - Fee Related
- 2003-06-18 AT AT03760997T patent/ATE454383T1/de not_active IP Right Cessation
- 2003-06-18 DE DE60330864T patent/DE60330864D1/de not_active Expired - Lifetime
- 2003-06-18 CN CNB038141310A patent/CN100484933C/zh not_active Expired - Fee Related
- 2003-06-18 EP EP03760997A patent/EP1513831B1/en not_active Expired - Lifetime
- 2003-06-18 MX MXPA04012711A patent/MXPA04012711A/es not_active Application Discontinuation
- 2003-06-18 WO PCT/SE2003/001044 patent/WO2004000830A1/en active Application Filing
- 2003-06-18 EA EA200500045A patent/EA008148B1/ru not_active IP Right Cessation
- 2003-06-18 IL IL16522003A patent/IL165220A0/xx unknown
- 2003-06-18 BR BR0311970-0A patent/BR0311970A/pt not_active IP Right Cessation
- 2003-06-18 NZ NZ536664A patent/NZ536664A/en not_active IP Right Cessation
- 2003-06-18 AU AU2003243089A patent/AU2003243089B2/en not_active Ceased
-
2005
- 2005-01-17 NO NO20050270A patent/NO20050270L/no not_active Application Discontinuation
- 2005-12-19 HK HK05111675.4A patent/HK1079526A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2003243089B2 (en) | 2010-01-07 |
NZ536664A (en) | 2007-07-27 |
WO2004000830A1 (en) | 2003-12-31 |
BR0311970A (pt) | 2005-03-29 |
JP4460450B2 (ja) | 2010-05-12 |
MXPA04012711A (es) | 2005-03-23 |
AU2003243089A1 (en) | 2004-01-06 |
EP1513831B1 (en) | 2010-01-06 |
CN100484933C (zh) | 2009-05-06 |
ATE454383T1 (de) | 2010-01-15 |
EA200500045A1 (ru) | 2005-06-30 |
DE60330864D1 (de) | 2010-02-25 |
CA2485537A1 (en) | 2003-12-31 |
JP2005532409A (ja) | 2005-10-27 |
IL165220A0 (en) | 2005-12-18 |
EP1513831A1 (en) | 2005-03-16 |
CN1662522A (zh) | 2005-08-31 |
EA008148B1 (ru) | 2007-04-27 |
HK1079526A1 (en) | 2006-04-07 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |