NO20044979L - Nye biomaterialer, deres fremstilling og anvendelse - Google Patents
Nye biomaterialer, deres fremstilling og anvendelseInfo
- Publication number
- NO20044979L NO20044979L NO20044979A NO20044979A NO20044979L NO 20044979 L NO20044979 L NO 20044979L NO 20044979 A NO20044979 A NO 20044979A NO 20044979 A NO20044979 A NO 20044979A NO 20044979 L NO20044979 L NO 20044979L
- Authority
- NO
- Norway
- Prior art keywords
- precipitate
- components
- additional
- component
- amphilic
- Prior art date
Links
- 239000012620 biological material Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002244 precipitate Substances 0.000 abstract 8
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 2
- 229920006318 anionic polymer Polymers 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 239000003905 agrochemical Substances 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000575 pesticide Substances 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Foreliggende oppfinnelse angår nye materialer, særlig biomaterialer, i form av et presipitat, som innbefatter minst en anionisk polymerkomponent som sådan er løselig i vann og en amfilisk ammoniumtypekomponent, hvilket presipitat oppnås ved en fremgangsmåte som inkluderer følgende trinn: 1. bringe den anioniske polymerkomponenten og en cyklodekstrinkomponent i kontakt i et vandig medium, og 2. tilsette til blandingen oppnådd i trinn 1 nevnte amfiliske ammoniumtypekomponent, hvori nevnte komponenter er tilstede i mengder effektive til å danne nevnte presipitat, og foretrukket for de korresponderende presipitatene innbefatter de ytterligere nevnte cyklodekstrinkomponent. Begge typer presipitat kan eventuelt innbefatte en eller flere ytterligere komponenter. Presipitatene er særlig anvendelige for kontrollert frigivelses depotformuleringer egnet for langtidsvirkende levering av nevnte ytterligere komponenter. De ytterligere komponentene inkorporert i presipitatene kan være farmasøytiske forbindelser, pesticider, agrokjemikalier, fargestoffer, diagnostiske midler, enzymer, matvarer etc.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02008809 | 2002-04-19 | ||
PCT/EP2003/004076 WO2003089008A1 (en) | 2002-04-19 | 2003-04-17 | Novel biomaterials, their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20044979L true NO20044979L (no) | 2004-11-16 |
Family
ID=29225593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20044979A NO20044979L (no) | 2002-04-19 | 2004-11-16 | Nye biomaterialer, deres fremstilling og anvendelse |
Country Status (20)
Country | Link |
---|---|
US (3) | US20050163853A1 (no) |
EP (1) | EP1499361B1 (no) |
JP (1) | JP4648632B2 (no) |
KR (1) | KR101121675B1 (no) |
CN (1) | CN1646171B (no) |
AU (1) | AU2003224099B2 (no) |
BR (1) | BR0309340A (no) |
CA (1) | CA2484100C (no) |
CO (1) | CO5611168A2 (no) |
ES (1) | ES2392964T3 (no) |
HK (1) | HK1073070A1 (no) |
IL (1) | IL164627A (no) |
MX (1) | MXPA04010325A (no) |
NO (1) | NO20044979L (no) |
NZ (1) | NZ535810A (no) |
PL (1) | PL215579B1 (no) |
PT (1) | PT1499361E (no) |
RU (1) | RU2321597C2 (no) |
WO (1) | WO2003089008A1 (no) |
ZA (1) | ZA200407794B (no) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
BRPI0506983A (pt) * | 2004-01-20 | 2007-07-03 | Allergan Inc | composições para terapia localizada dos olhos, compreendendo preferencialmente acetonida de triancinolona e ácido hialurÈnico |
WO2006011044A1 (en) * | 2004-07-22 | 2006-02-02 | Pfizer Products Inc. | Amorphous cyclodextrin compositions |
US20060089590A1 (en) * | 2004-10-27 | 2006-04-27 | John Higuchi | Methods and devices for sustained in-vivo release of an active agent |
EP1787658B1 (en) | 2005-11-10 | 2012-03-14 | CHEMI S.p.A. | Sustained release formulations of somatostatin analogue inhibitors of growth hormone |
US20100155242A1 (en) * | 2006-09-04 | 2010-06-24 | Arkray, Inc. | Method of Analyzing a Sample by Capillary Electrophoresis |
CN101501484B (zh) * | 2006-09-04 | 2012-12-26 | 独立行政法人产业技术综合研究所 | 通过毛细管电泳法分析试样的方法 |
JP2009186445A (ja) * | 2008-02-08 | 2009-08-20 | Arkray Inc | キャピラリー電気泳動法によるヘモグロビンの分析方法およびそれに用いる試薬 |
EP2060913B1 (en) * | 2006-09-04 | 2016-11-02 | National Institute of Advanced Industrial Science and Technology | Method for analysis of sample by capillary electrophoresis |
CA2753641C (en) * | 2009-02-25 | 2014-09-16 | Supratek Pharma, Inc. | Bendamustine cyclopolysaccharide compositions |
US8389558B2 (en) * | 2009-07-20 | 2013-03-05 | Supratek Pharma Inc. | Bendamustine amphiphilic anionic compositions |
US20110015245A1 (en) * | 2009-07-20 | 2011-01-20 | Valery Alakhov | Bendamustine amphiphilic cationic compositions |
RU2552927C2 (ru) | 2010-03-13 | 2015-06-10 | Истпонд Лабораториз Лимитед | Жиросвязывающая композиция |
US8383663B2 (en) | 2010-07-19 | 2013-02-26 | Supratek Pharma Inc. | Bendamustine anionic-catioinic cyclopolysaccharide compositions |
BR112013016809A2 (pt) | 2010-12-31 | 2016-09-27 | Eastpond Lab Ltd | composições de hidratação celular |
US20120171184A1 (en) | 2010-12-31 | 2012-07-05 | Lajos Szente | Cellular hydration compositions |
CN103347386B (zh) * | 2011-02-10 | 2016-08-10 | 荷兰联合利华有限公司 | 抗微生物组合物 |
MX356582B (es) | 2012-01-18 | 2018-06-05 | Surmodics Inc | Recubrimiento para dispositivo medico lubrico con bajo nivel de material particulado. |
EP2928500B1 (en) * | 2012-12-04 | 2019-03-06 | Phosphorex Inc. | Microparticles and nanoparticles having negative surface charges |
JP6449249B2 (ja) * | 2013-05-17 | 2019-01-09 | マーケット ユニバーシティー | イオン性液体組成物から形成される構造多糖および大環状化合物を含有する複合材料 |
JP5673756B2 (ja) * | 2013-08-20 | 2015-02-18 | 東洋紡株式会社 | 医療用材料 |
RU2597085C2 (ru) * | 2013-11-07 | 2016-09-10 | Федеральное государственное бюджетное учреждение науки Институт биологии моря им. А.В. Жирмунского Дальневосточного отделения Российской академии наук (ИБМ ДВО РАН) | Имплантируемый матриксный материал для регенеративной медицины и способ его получения (варианты) |
WO2016206738A1 (en) | 2015-06-24 | 2016-12-29 | Kao Germany Gmbh | Hair treatment process |
US11174447B2 (en) | 2015-12-29 | 2021-11-16 | Surmodics, Inc. | Lubricious coatings with surface salt groups |
US10342898B2 (en) * | 2015-12-29 | 2019-07-09 | Surmodics, Inc. | Lubricious coatings with surface salt groups |
EP3528856B1 (en) | 2016-10-18 | 2023-07-12 | Marquette University | Composite materials containing structural polymers and photoreactive nitric oxide releasing agents and uses thereof for wound dressings |
MX2022012532A (es) | 2020-04-06 | 2023-03-15 | Eastpond Laboratories Ltd | Composiciones y métodos para promover la hidratación celular. |
CN114344557A (zh) * | 2022-01-10 | 2022-04-15 | 山东万容生物科技有限公司 | 一种含环糊精的水胶体敷料及其制备方法 |
WO2023212740A1 (en) * | 2022-04-29 | 2023-11-02 | Drexel University | Surfactant-impregnated mof-coated fabric for antimicrobial applications |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE670837A (no) * | 1964-10-14 | 1966-01-31 | ||
JPS61251616A (ja) * | 1985-04-30 | 1986-11-08 | Agency Of Ind Science & Technol | 溶質の放出量の制御方法 |
JPS6416728A (en) * | 1987-07-07 | 1989-01-20 | Santen Pharmaceutical Co Ltd | Aqueous preparation |
JPH03234770A (ja) * | 1990-02-09 | 1991-10-18 | Nippon Shokubai Kagaku Kogyo Co Ltd | 電気刺激応答性ゲルの製法 |
US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
US5464650A (en) * | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
SE9303627D0 (sv) * | 1993-11-03 | 1993-11-03 | Kabi Pharmacia Ab | Method and means for prevention of cataract |
JPH08134134A (ja) * | 1994-11-09 | 1996-05-28 | Nippon Shokubai Co Ltd | 粒子状含水ゲル重合体の乾燥方法 |
JP3297969B2 (ja) * | 1994-12-26 | 2002-07-02 | ライオン株式会社 | 点眼剤 |
TW434023B (en) * | 1995-09-18 | 2001-05-16 | Novartis Ag | Preserved ophthalmic composition |
JPH0995413A (ja) * | 1995-09-29 | 1997-04-08 | Shiseido Co Ltd | 皮膚外用剤 |
GB9718568D0 (en) * | 1997-09-03 | 1997-11-05 | Chauvin Pharmaceuticals Limite | Compositions |
WO2000004916A1 (en) * | 1998-07-23 | 2000-02-03 | Societe De Conseils De Recherches Et D'applications Scientifiques Sas | Encapsulation of water soluble peptides |
EP1144456A3 (en) * | 1999-01-12 | 2002-09-11 | Vito-Mannan Polysaccharide L.L.C. | Method of isolating mucilaginous polysaccharides and uses thereof |
JP2001318350A (ja) * | 2000-05-11 | 2001-11-16 | Lion Corp | コンタクトレンズ用溶液 |
AU2001261403B2 (en) * | 2000-05-15 | 2006-04-06 | The Procter & Gamble Company | Compositions comprising cyclodextrin |
US20020147232A1 (en) * | 2000-05-26 | 2002-10-10 | Claus Sundgreen | Pharmaceutical compositions comprising desglymidodrine as an active drug substance |
PE20020146A1 (es) * | 2000-07-13 | 2002-03-31 | Upjohn Co | Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2) |
US6541510B2 (en) * | 2000-09-28 | 2003-04-01 | Immugen Pharmaceuticals, Inc. | Antiviral methods and compounds |
-
2003
- 2003-04-17 PT PT03720497T patent/PT1499361E/pt unknown
- 2003-04-17 AU AU2003224099A patent/AU2003224099B2/en not_active Ceased
- 2003-04-17 PL PL371595A patent/PL215579B1/pl unknown
- 2003-04-17 US US10/511,075 patent/US20050163853A1/en not_active Abandoned
- 2003-04-17 NZ NZ535810A patent/NZ535810A/en not_active IP Right Cessation
- 2003-04-17 RU RU2004133887/04A patent/RU2321597C2/ru not_active IP Right Cessation
- 2003-04-17 ES ES03720497T patent/ES2392964T3/es not_active Expired - Lifetime
- 2003-04-17 CA CA2484100A patent/CA2484100C/en not_active Expired - Fee Related
- 2003-04-17 EP EP03720497A patent/EP1499361B1/en not_active Expired - Lifetime
- 2003-04-17 BR BR0309340-9A patent/BR0309340A/pt not_active IP Right Cessation
- 2003-04-17 MX MXPA04010325A patent/MXPA04010325A/es active IP Right Grant
- 2003-04-17 CN CN038088592A patent/CN1646171B/zh not_active Expired - Fee Related
- 2003-04-17 JP JP2003585759A patent/JP4648632B2/ja not_active Expired - Fee Related
- 2003-04-17 WO PCT/EP2003/004076 patent/WO2003089008A1/en active Application Filing
- 2003-04-17 KR KR1020047016698A patent/KR101121675B1/ko not_active IP Right Cessation
-
2004
- 2004-09-28 ZA ZA200407794A patent/ZA200407794B/xx unknown
- 2004-10-14 IL IL164627A patent/IL164627A/en not_active IP Right Cessation
- 2004-10-26 CO CO04107397A patent/CO5611168A2/es active IP Right Grant
- 2004-11-16 NO NO20044979A patent/NO20044979L/no not_active Application Discontinuation
-
2005
- 2005-07-07 HK HK05105740.7A patent/HK1073070A1/xx unknown
-
2008
- 2008-07-24 US US12/178,934 patent/US20080299166A1/en not_active Abandoned
-
2011
- 2011-10-25 US US13/281,033 patent/US20120040901A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2484100C (en) | 2012-01-03 |
US20080299166A1 (en) | 2008-12-04 |
ZA200407794B (en) | 2006-02-22 |
PL215579B1 (pl) | 2013-12-31 |
CO5611168A2 (es) | 2006-02-28 |
ES2392964T3 (es) | 2012-12-17 |
HK1073070A1 (en) | 2005-09-23 |
EP1499361B1 (en) | 2012-08-08 |
IL164627A (en) | 2009-11-18 |
US20050163853A1 (en) | 2005-07-28 |
US20120040901A1 (en) | 2012-02-16 |
PL371595A1 (en) | 2005-06-27 |
CN1646171B (zh) | 2010-05-26 |
KR101121675B1 (ko) | 2012-03-13 |
RU2004133887A (ru) | 2005-10-20 |
CA2484100A1 (en) | 2003-10-30 |
EP1499361A1 (en) | 2005-01-26 |
IL164627A0 (en) | 2005-12-18 |
NZ535810A (en) | 2007-11-30 |
MXPA04010325A (es) | 2005-06-08 |
CN1646171A (zh) | 2005-07-27 |
PT1499361E (pt) | 2012-11-22 |
BR0309340A (pt) | 2005-03-08 |
AU2003224099B2 (en) | 2006-11-09 |
WO2003089008A1 (en) | 2003-10-30 |
AU2003224099A1 (en) | 2003-11-03 |
KR20040103968A (ko) | 2004-12-09 |
JP4648632B2 (ja) | 2011-03-09 |
RU2321597C2 (ru) | 2008-04-10 |
JP2005529879A (ja) | 2005-10-06 |
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