NO20041651L - Anvendelse av (11 beta,17 beta)-11-(1,3-benzodioksol-5-yl)-17-hydroksy-17-(1-propynyl)-ostra-4,9-dien-3-on for behandling av alvorlig depressiv forstyrrelse - Google Patents
Anvendelse av (11 beta,17 beta)-11-(1,3-benzodioksol-5-yl)-17-hydroksy-17-(1-propynyl)-ostra-4,9-dien-3-on for behandling av alvorlig depressiv forstyrrelseInfo
- Publication number
- NO20041651L NO20041651L NO20041651A NO20041651A NO20041651L NO 20041651 L NO20041651 L NO 20041651L NO 20041651 A NO20041651 A NO 20041651A NO 20041651 A NO20041651 A NO 20041651A NO 20041651 L NO20041651 L NO 20041651L
- Authority
- NO
- Norway
- Prior art keywords
- beta
- benzodioxol
- dien
- propynyl
- hydroxy
- Prior art date
Links
- 208000020401 Depressive disease Diseases 0.000 title abstract 2
- -1 1,3-benzodioxol-5-yl Chemical group 0.000 title 1
- 125000000530 1-propynyl group Chemical group [H]C([H])([H])C#C* 0.000 title 1
- DFELGYQKEOCHOA-BZAFBGKRSA-N (8s,11r,13s,14s,17s)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one Chemical compound C1=C2OCOC2=CC([C@@H]2C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]3CC[C@@]([C@]3(C2)C)(O)C#CC)=C1 DFELGYQKEOCHOA-BZAFBGKRSA-N 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 229940126013 glucocorticoid receptor antagonist Drugs 0.000 abstract 1
- 239000003850 glucocorticoid receptor antagonist Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Foreliggende oppfinnelse angår anvendelse av glukokortikoidreseptorantagonisten (lip,17P)-ll-(l,3-benzodioksol-5-yl)-17-hydroksy-17-(lpropynyl)-østra-4,9-dien-3-on (Org 34517) for fremstilling av et medikament for behandling av depresjon så vel som farmasøytiske preparater av Org 34517 for nevnte anvendelse.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01204072 | 2001-10-26 | ||
PCT/EP2002/011732 WO2003037354A1 (en) | 2001-10-26 | 2002-10-21 | USE OF (11β, 17β)-11-(1,3-BENZODIOXOL-5-YL)-17-HYDROXY-17-(1-PROPYNYL)-ESTRA-4,9-DIEN-3-ONE IN THE TREATMENT OF MAJOR DEPRESSIVE DISORDER |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20041651L true NO20041651L (no) | 2004-04-23 |
NO332978B1 NO332978B1 (no) | 2013-02-11 |
Family
ID=8181136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20041651A NO332978B1 (no) | 2001-10-26 | 2004-04-23 | Anvendelse av (11ß,17ß)-11-(1,3-benzodioksol-5-yl)-17-hydroksy-17-(1-propynyl)-ostra-4,9-dien-3-on for behandling av alvorlig depressiv forstyrrelse |
Country Status (27)
Country | Link |
---|---|
US (1) | US20040266863A1 (no) |
EP (2) | EP1441739B1 (no) |
JP (1) | JP4647909B2 (no) |
KR (1) | KR20050038580A (no) |
CN (1) | CN100531738C (no) |
AT (2) | ATE420649T1 (no) |
AU (1) | AU2002348996B2 (no) |
BR (1) | BR0213466A (no) |
CA (1) | CA2463446C (no) |
CY (1) | CY1110173T1 (no) |
DE (2) | DE60230936D1 (no) |
DK (1) | DK1652526T3 (no) |
EC (1) | ECSP045080A (no) |
ES (1) | ES2319563T3 (no) |
HK (1) | HK1087357A1 (no) |
HR (1) | HRP20040370B1 (no) |
HU (1) | HUP0500070A3 (no) |
IL (2) | IL161248A0 (no) |
IS (1) | IS2702B (no) |
MX (1) | MXPA04003781A (no) |
NO (1) | NO332978B1 (no) |
NZ (1) | NZ532429A (no) |
PL (1) | PL206687B1 (no) |
PT (1) | PT1652526E (no) |
RU (1) | RU2302245C2 (no) |
WO (1) | WO2003037354A1 (no) |
ZA (1) | ZA200403088B (no) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050080061A1 (en) * | 2003-07-23 | 2005-04-14 | Corcept Therapeutics, Inc. | Antiglucocorticoid therapy for the prevention of neurological damage in premature infants |
MX2007006045A (es) * | 2004-11-19 | 2007-06-13 | Organon Nv | Combinacion farmaceutica que comprende inhibidor selectivo de reabsorcion de serotonina y antagonista del receptor de glucocorticoide para tratamiento de depresion. |
AU2011236053B2 (en) * | 2004-11-19 | 2014-06-26 | Merck Sharpe & Dohme B.V. | Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression |
EP2012796A4 (en) * | 2006-05-02 | 2010-08-11 | Corcept Therapeutics Inc | USE OF GLUCOCORTICOID TYPE II RECEPTOR ANTAGONISTS TO TREAT PATIENT DEPRESSION WITH IL-2 |
WO2012106514A2 (en) * | 2011-02-03 | 2012-08-09 | Pop Test Cortisol Llc | System and method for diagnosis and treatment |
US20120263660A1 (en) * | 2011-04-18 | 2012-10-18 | Pop Test Cortisol Llc | Hair Loss Treatment |
US8986677B2 (en) * | 2012-07-30 | 2015-03-24 | Pop Test Cortisol Llc | Therapeutic compositions and methods |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4814333A (en) * | 1987-07-28 | 1989-03-21 | The Trustees Of Dartmouth College | Method for treatment of hypercortisolemic, depressed patients |
IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
DE19727772A1 (de) * | 1997-06-30 | 1999-01-28 | Forschungszentrum Juelich Gmbh | Magnetflußsensor mit ringförmiger Sonde |
ATE332696T1 (de) * | 1997-10-06 | 2006-08-15 | Univ Leland Stanford Junior | Methode zur behandlung von durch glycocorticoidstörungen verursachten psychosen |
IL157770A0 (en) * | 2001-03-23 | 2004-03-28 | Corcept Therapeutics Inc | Methods for treating stress disorders using glucocorticoid receptor-specific antagonists |
WO2002096433A1 (en) * | 2001-05-04 | 2002-12-05 | Corcept Therapeutics, Inc. | Methods for treating delirium using glucocorticoid receptor-specific antagonists |
EP1432379B1 (en) * | 2001-08-31 | 2008-10-15 | Corcept Therapeutics, Inc. | Methods for inhibiting cognitive deterioration in adults with down's syndrome |
-
2002
- 2002-10-21 HU HU0500070A patent/HUP0500070A3/hu unknown
- 2002-10-21 MX MXPA04003781A patent/MXPA04003781A/es active IP Right Grant
- 2002-10-21 AU AU2002348996A patent/AU2002348996B2/en not_active Ceased
- 2002-10-21 PT PT06101005T patent/PT1652526E/pt unknown
- 2002-10-21 EP EP02781273A patent/EP1441739B1/en not_active Withdrawn - After Issue
- 2002-10-21 CA CA2463446A patent/CA2463446C/en not_active Expired - Fee Related
- 2002-10-21 DE DE60230936T patent/DE60230936D1/de not_active Expired - Lifetime
- 2002-10-21 CN CNB028210417A patent/CN100531738C/zh not_active Expired - Fee Related
- 2002-10-21 PL PL369261A patent/PL206687B1/pl not_active IP Right Cessation
- 2002-10-21 AT AT06101005T patent/ATE420649T1/de active
- 2002-10-21 DE DE60209248T patent/DE60209248D1/de not_active Expired - Lifetime
- 2002-10-21 AT AT02781273T patent/ATE317700T1/de active
- 2002-10-21 US US10/493,981 patent/US20040266863A1/en not_active Abandoned
- 2002-10-21 BR BR0213466-7A patent/BR0213466A/pt not_active IP Right Cessation
- 2002-10-21 IL IL16124802A patent/IL161248A0/xx unknown
- 2002-10-21 WO PCT/EP2002/011732 patent/WO2003037354A1/en not_active Application Discontinuation
- 2002-10-21 KR KR1020047006050A patent/KR20050038580A/ko not_active Application Discontinuation
- 2002-10-21 DK DK06101005T patent/DK1652526T3/da active
- 2002-10-21 ES ES06101005T patent/ES2319563T3/es not_active Expired - Lifetime
- 2002-10-21 EP EP06101005A patent/EP1652526B1/en not_active Expired - Lifetime
- 2002-10-21 NZ NZ532429A patent/NZ532429A/en not_active IP Right Cessation
- 2002-10-21 RU RU2004116082/15A patent/RU2302245C2/ru not_active IP Right Cessation
- 2002-10-21 JP JP2003539697A patent/JP4647909B2/ja not_active Expired - Fee Related
-
2004
- 2004-03-31 IS IS7204A patent/IS2702B/is unknown
- 2004-04-01 IL IL161248A patent/IL161248A/en not_active IP Right Cessation
- 2004-04-22 ZA ZA200403088A patent/ZA200403088B/en unknown
- 2004-04-23 EC EC2004005080A patent/ECSP045080A/es unknown
- 2004-04-23 NO NO20041651A patent/NO332978B1/no not_active IP Right Cessation
- 2004-04-26 HR HRP20040370AA patent/HRP20040370B1/xx not_active IP Right Cessation
-
2006
- 2006-08-29 HK HK06109619.6A patent/HK1087357A1/xx not_active IP Right Cessation
-
2009
- 2009-02-02 CY CY20091100116T patent/CY1110173T1/el unknown
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