HUP0500070A2 - (11béta,17béta)-11-(1,3-Benzodioxol-5-il)-17-hidroxi-17-(1-propinil)-ösztra-4,9-dién-3-on alkalmazása nagyfokú depresszív rendellenesség kezelésére szolgáló gyógyszerkészítmény előállítására - Google Patents

(11béta,17béta)-11-(1,3-Benzodioxol-5-il)-17-hidroxi-17-(1-propinil)-ösztra-4,9-dién-3-on alkalmazása nagyfokú depresszív rendellenesség kezelésére szolgáló gyógyszerkészítmény előállítására

Info

Publication number
HUP0500070A2
HUP0500070A2 HU0500070A HUP0500070A HUP0500070A2 HU P0500070 A2 HUP0500070 A2 HU P0500070A2 HU 0500070 A HU0500070 A HU 0500070A HU P0500070 A HUP0500070 A HU P0500070A HU P0500070 A2 HUP0500070 A2 HU P0500070A2
Authority
HU
Hungary
Prior art keywords
estra
benzodioxol
dien
propynyl
treatment
Prior art date
Application number
HU0500070A
Other languages
English (en)
Inventor
Cornelis Sennef
Bernardus Wijnand Mathys Marie Peeters
Original Assignee
Akzo Nobel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.
Publication of HUP0500070A2 publication Critical patent/HUP0500070A2/hu
Publication of HUP0500070A3 publication Critical patent/HUP0500070A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány tárgya (11<, 17<)-11-(1,3-benzodioxol-5-il)-17-hidroxi-l7-(1propinil)-ösztra-4,9-dién-3-on alkalmazása nagyfokú depresszívrendellenesség kezelésére alkalmas gyógyszerkészítmény előállítására.A találmány kiterjed a fenti hatóanyagot tartalmazógyógyszerkészítményre is. A találmány szerinti megoldás jellemzővonása, hogy a hatóanyagot legfeljebb 300 mg napi dózisbanalkalmazzák. Ó
HU0500070A 2001-10-26 2002-10-21 Use of (11betha,17betha)-11-(1,3-benzodioxol-5-yl)-17-(1-propynyl)-estra-4,9-dien-3-one for producing pharmaceutical compositions for the treatment of major depressive disorder HUP0500070A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01204072 2001-10-26
PCT/EP2002/011732 WO2003037354A1 (en) 2001-10-26 2002-10-21 USE OF (11β, 17β)-11-(1,3-BENZODIOXOL-5-YL)-17-HYDROXY-17-(1-PROPYNYL)-ESTRA-4,9-DIEN-3-ONE IN THE TREATMENT OF MAJOR DEPRESSIVE DISORDER

Publications (2)

Publication Number Publication Date
HUP0500070A2 true HUP0500070A2 (hu) 2005-04-28
HUP0500070A3 HUP0500070A3 (en) 2012-09-28

Family

ID=8181136

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0500070A HUP0500070A3 (en) 2001-10-26 2002-10-21 Use of (11betha,17betha)-11-(1,3-benzodioxol-5-yl)-17-(1-propynyl)-estra-4,9-dien-3-one for producing pharmaceutical compositions for the treatment of major depressive disorder

Country Status (27)

Country Link
US (1) US20040266863A1 (hu)
EP (2) EP1652526B1 (hu)
JP (1) JP4647909B2 (hu)
KR (1) KR20050038580A (hu)
CN (1) CN100531738C (hu)
AT (2) ATE420649T1 (hu)
AU (1) AU2002348996B2 (hu)
BR (1) BR0213466A (hu)
CA (1) CA2463446C (hu)
CY (1) CY1110173T1 (hu)
DE (2) DE60209248D1 (hu)
DK (1) DK1652526T3 (hu)
EC (1) ECSP045080A (hu)
ES (1) ES2319563T3 (hu)
HK (1) HK1087357A1 (hu)
HR (1) HRP20040370B1 (hu)
HU (1) HUP0500070A3 (hu)
IL (2) IL161248A0 (hu)
IS (1) IS2702B (hu)
MX (1) MXPA04003781A (hu)
NO (1) NO332978B1 (hu)
NZ (1) NZ532429A (hu)
PL (1) PL206687B1 (hu)
PT (1) PT1652526E (hu)
RU (1) RU2302245C2 (hu)
WO (1) WO2003037354A1 (hu)
ZA (1) ZA200403088B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050080061A1 (en) * 2003-07-23 2005-04-14 Corcept Therapeutics, Inc. Antiglucocorticoid therapy for the prevention of neurological damage in premature infants
MX2007006045A (es) * 2004-11-19 2007-06-13 Organon Nv Combinacion farmaceutica que comprende inhibidor selectivo de reabsorcion de serotonina y antagonista del receptor de glucocorticoide para tratamiento de depresion.
AU2011236053B2 (en) * 2004-11-19 2014-06-26 Merck Sharpe & Dohme B.V. Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression
JP2009535430A (ja) * 2006-05-02 2009-10-01 コーセプト セラピューティクス， インコーポレイテッド Ｉｌ−２を摂取している患者における抑うつを処置するためのグルココルチコイドレセプターｉｉアンタゴニストの使用
US8658128B2 (en) 2011-02-03 2014-02-25 Pop Test Cortisol Llc System and method for diagnosis and treatment
EP2699245A4 (en) * 2011-04-18 2014-12-10 Pop Test Cortisol Llc TREATMENT AGAINST HAIR LOSS
US8986677B2 (en) * 2012-07-30 2015-03-24 Pop Test Cortisol Llc Therapeutic compositions and methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814333A (en) * 1987-07-28 1989-03-21 The Trustees Of Dartmouth College Method for treatment of hypercortisolemic, depressed patients
IL118974A (en) * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
DE19727772A1 (de) * 1997-06-30 1999-01-28 Forschungszentrum Juelich Gmbh Magnetflußsensor mit ringförmiger Sonde
DE69835225T2 (de) * 1997-10-06 2007-07-05 The Board Of Trustees Of The Leland Stanford Junior University, Palo Alto Methode zur behandlung von durch glycocorticoidstörungen verursachten psychosen
DK1370268T3 (da) * 2001-03-23 2009-09-14 Corcept Therapeutics Inc Fremgangsmåde til behandling af stresssygdomme under anvendelse af glucocorticoid-receptor-specifikke antagonister
JP2005512949A (ja) * 2001-05-04 2005-05-12 コーセプト セラピューティクス， インコーポレイテッド グルココルチコイドレセプターに特異的なアンタゴニストを使用して、せん妄を処置する方法
IL160649A0 (en) * 2001-08-31 2004-07-25 Corcept Therapeutics Inc Methods for inhibiting cognitive deterioration in adults with down syndrome

Also Published As

Publication number Publication date
ES2319563T3 (es) 2009-05-08
CA2463446A1 (en) 2003-05-08
CA2463446C (en) 2010-02-23
ATE420649T1 (de) 2009-01-15
IL161248A0 (en) 2004-09-27
BR0213466A (pt) 2004-11-09
CN100531738C (zh) 2009-08-26
NZ532429A (en) 2004-10-29
US20040266863A1 (en) 2004-12-30
RU2004116082A (ru) 2005-05-10
NO20041651L (no) 2004-04-23
RU2302245C2 (ru) 2007-07-10
KR20050038580A (ko) 2005-04-27
CY1110173T1 (el) 2015-01-14
EP1441739B1 (en) 2006-02-15
HRP20040370B1 (en) 2012-09-30
AU2002348996B2 (en) 2008-06-05
EP1652526B1 (en) 2009-01-14
DE60230936D1 (de) 2009-03-05
IS7204A (is) 2004-03-31
PL206687B1 (pl) 2010-09-30
MXPA04003781A (es) 2004-07-30
JP2005521637A (ja) 2005-07-21
EP1441739A1 (en) 2004-08-04
NO332978B1 (no) 2013-02-11
DE60209248D1 (de) 2006-04-20
JP4647909B2 (ja) 2011-03-09
ECSP045080A (es) 2004-06-28
PT1652526E (pt) 2009-02-06
IL161248A (en) 2010-12-30
HK1087357A1 (en) 2006-10-13
DK1652526T3 (da) 2009-05-18
WO2003037354A1 (en) 2003-05-08
CN1582153A (zh) 2005-02-16
PL369261A1 (en) 2005-04-18
HUP0500070A3 (en) 2012-09-28
ATE317700T1 (de) 2006-03-15
HRP20040370A2 (en) 2004-08-31
ZA200403088B (en) 2005-01-24
IS2702B (is) 2010-11-15
EP1652526A3 (en) 2006-08-02
EP1652526A2 (en) 2006-05-03

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: N.V. ORGANON, NL

Free format text: FORMER OWNER(S): AKZO NOBEL N.V., NL

GB9A Succession in title

Owner name: POP TEST CORTISOL LLC, US

Free format text: FORMER OWNER(S): AKZO NOBEL N.V., NL; N.V. ORGANON, NL

FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished