IS7204A - Notkun á (11ß, 17ß)-11-(1,3-bensódíoxól-5-ýl)-17-hýdroxý-17-(1-própýnýl)-estra-4,9-díen-3-ón við meðhöndlun á stórvægilegri geðlægðartruflun - Google Patents
Notkun á (11ß, 17ß)-11-(1,3-bensódíoxól-5-ýl)-17-hýdroxý-17-(1-própýnýl)-estra-4,9-díen-3-ón við meðhöndlun á stórvægilegri geðlægðartruflunInfo
- Publication number
- IS7204A IS7204A IS7204A IS7204A IS7204A IS 7204 A IS7204 A IS 7204A IS 7204 A IS7204 A IS 7204A IS 7204 A IS7204 A IS 7204A IS 7204 A IS7204 A IS 7204A
- Authority
- IS
- Iceland
- Prior art keywords
- benzodioxol
- propynyl
- hydroxy
- treatment
- din
- Prior art date
Links
- -1 1,3-benzodioxol-5-yl Chemical group 0.000 title 1
- 125000000530 1-propynyl group Chemical group [H]C([H])([H])C#C* 0.000 title 1
- 208000024714 major depressive disease Diseases 0.000 title 1
- DFELGYQKEOCHOA-BZAFBGKRSA-N (8s,11r,13s,14s,17s)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one Chemical compound C1=C2OCOC2=CC([C@@H]2C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]3CC[C@@]([C@]3(C2)C)(O)C#CC)=C1 DFELGYQKEOCHOA-BZAFBGKRSA-N 0.000 abstract 2
- DBLOJPKZEOYNBN-SQNIBIBYSA-N (8s,13s,14s)-13-methyl-2,6,7,8,11,12,14,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-3-one Chemical compound C1CC2=CC(=O)CCC2=C2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 DBLOJPKZEOYNBN-SQNIBIBYSA-N 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940126013 glucocorticoid receptor antagonist Drugs 0.000 abstract 1
- 239000003850 glucocorticoid receptor antagonist Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01204072 | 2001-10-26 | ||
| PCT/EP2002/011732 WO2003037354A1 (en) | 2001-10-26 | 2002-10-21 | USE OF (11β, 17β)-11-(1,3-BENZODIOXOL-5-YL)-17-HYDROXY-17-(1-PROPYNYL)-ESTRA-4,9-DIEN-3-ONE IN THE TREATMENT OF MAJOR DEPRESSIVE DISORDER |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IS7204A true IS7204A (is) | 2004-03-31 |
| IS2702B IS2702B (is) | 2010-11-15 |
Family
ID=8181136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7204A IS2702B (is) | 2001-10-26 | 2004-03-31 | Notkun á (11beta, 17beta)-11-(1,3-bensódíoxól-5-ýl)-17-hýdroxý-17-(1-própýnýl)-estra-4,9-díen-3-ón í meðhöndluninni á alvarlegri geðdeyfðartruflun |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US20040266863A1 (is) |
| EP (2) | EP1652526B1 (is) |
| JP (1) | JP4647909B2 (is) |
| KR (1) | KR20050038580A (is) |
| CN (1) | CN100531738C (is) |
| AT (2) | ATE420649T1 (is) |
| AU (1) | AU2002348996B2 (is) |
| BR (1) | BR0213466A (is) |
| CA (1) | CA2463446C (is) |
| CY (1) | CY1110173T1 (is) |
| DE (2) | DE60209248D1 (is) |
| DK (1) | DK1652526T3 (is) |
| EC (1) | ECSP045080A (is) |
| ES (1) | ES2319563T3 (is) |
| HR (1) | HRP20040370B1 (is) |
| HU (1) | HUP0500070A3 (is) |
| IL (2) | IL161248A0 (is) |
| IS (1) | IS2702B (is) |
| MX (1) | MXPA04003781A (is) |
| NO (1) | NO332978B1 (is) |
| NZ (1) | NZ532429A (is) |
| PL (1) | PL206687B1 (is) |
| PT (1) | PT1652526E (is) |
| RU (1) | RU2302245C2 (is) |
| WO (1) | WO2003037354A1 (is) |
| ZA (1) | ZA200403088B (is) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050080061A1 (en) * | 2003-07-23 | 2005-04-14 | Corcept Therapeutics, Inc. | Antiglucocorticoid therapy for the prevention of neurological damage in premature infants |
| AU2011236053B2 (en) * | 2004-11-19 | 2014-06-26 | Merck Sharpe & Dohme B.V. | Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression |
| CA2585317C (en) * | 2004-11-19 | 2015-02-24 | N.V. Organon | Drug combination for the treatment of depression and related disorders comprising a selective serotonin reuptake inhibitor |
| JP2009535430A (ja) * | 2006-05-02 | 2009-10-01 | コーセプト セラピューティクス， インコーポレイテッド | Ｉｌ−２を摂取している患者における抑うつを処置するためのグルココルチコイドレセプターｉｉアンタゴニストの使用 |
| US8658128B2 (en) * | 2011-02-03 | 2014-02-25 | Pop Test Cortisol Llc | System and method for diagnosis and treatment |
| WO2012145258A1 (en) * | 2011-04-18 | 2012-10-26 | Pop Test Cortisol Llc | Hair loss treatment |
| US8986677B2 (en) * | 2012-07-30 | 2015-03-24 | Pop Test Cortisol Llc | Therapeutic compositions and methods |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4814333A (en) * | 1987-07-28 | 1989-03-21 | The Trustees Of Dartmouth College | Method for treatment of hypercortisolemic, depressed patients |
| DE4447401A1 (de) * | 1994-12-23 | 1996-07-04 | Schering Ag | 14,17-C¶2¶-überbrückte Steroide |
| IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| DE19727772A1 (de) * | 1997-06-30 | 1999-01-28 | Forschungszentrum Juelich Gmbh | Magnetflußsensor mit ringförmiger Sonde |
| AU747956B2 (en) * | 1997-10-06 | 2002-05-30 | Board Of Trustees Of The Leland Stanford Junior University | Methods for treating psychosis associated with glucocorticoid related dysfunction |
| JP2004525135A (ja) * | 2001-03-23 | 2004-08-19 | コーセプト セラピューティクス， インコーポレイテッド | 糖質コルチコイドレセプター特異的アンタゴニストを使用するストレス障害を処置するための方法 |
| ATE492281T1 (de) * | 2001-05-04 | 2011-01-15 | Corcept Therapeutics Inc | Verwendung von glucocorticoid-rezeptor- spezifischen antagonisten zur behandlung von delirium |
| ATE411013T1 (de) * | 2001-08-31 | 2008-10-15 | Corcept Therapeutics Inc | Verfahren zur hemmung der verschlechterung der kognitiven leistungsfähigkeit bei erwachsenen mit down-syndrom |
-
2002
- 2002-10-21 CN CNB028210417A patent/CN100531738C/zh not_active Expired - Fee Related
- 2002-10-21 PT PT06101005T patent/PT1652526E/pt unknown
- 2002-10-21 WO PCT/EP2002/011732 patent/WO2003037354A1/en not_active Ceased
- 2002-10-21 NZ NZ532429A patent/NZ532429A/en not_active IP Right Cessation
- 2002-10-21 BR BR0213466-7A patent/BR0213466A/pt not_active IP Right Cessation
- 2002-10-21 DE DE60209248T patent/DE60209248D1/de not_active Expired - Lifetime
- 2002-10-21 KR KR1020047006050A patent/KR20050038580A/ko not_active Ceased
- 2002-10-21 PL PL369261A patent/PL206687B1/pl not_active IP Right Cessation
- 2002-10-21 US US10/493,981 patent/US20040266863A1/en not_active Abandoned
- 2002-10-21 HU HU0500070A patent/HUP0500070A3/hu unknown
- 2002-10-21 ES ES06101005T patent/ES2319563T3/es not_active Expired - Lifetime
- 2002-10-21 EP EP06101005A patent/EP1652526B1/en not_active Expired - Lifetime
- 2002-10-21 DK DK06101005T patent/DK1652526T3/da active
- 2002-10-21 EP EP02781273A patent/EP1441739B1/en not_active Expired - Lifetime
- 2002-10-21 JP JP2003539697A patent/JP4647909B2/ja not_active Expired - Fee Related
- 2002-10-21 AU AU2002348996A patent/AU2002348996B2/en not_active Ceased
- 2002-10-21 HR HRP20040370AA patent/HRP20040370B1/xx not_active IP Right Cessation
- 2002-10-21 AT AT06101005T patent/ATE420649T1/de active
- 2002-10-21 MX MXPA04003781A patent/MXPA04003781A/es active IP Right Grant
- 2002-10-21 AT AT02781273T patent/ATE317700T1/de active
- 2002-10-21 RU RU2004116082/15A patent/RU2302245C2/ru not_active IP Right Cessation
- 2002-10-21 IL IL16124802A patent/IL161248A0/xx unknown
- 2002-10-21 DE DE60230936T patent/DE60230936D1/de not_active Expired - Lifetime
- 2002-10-21 CA CA2463446A patent/CA2463446C/en not_active Expired - Fee Related
-
2004
- 2004-03-31 IS IS7204A patent/IS2702B/is unknown
- 2004-04-01 IL IL161248A patent/IL161248A/en not_active IP Right Cessation
- 2004-04-22 ZA ZA200403088A patent/ZA200403088B/en unknown
- 2004-04-23 NO NO20041651A patent/NO332978B1/no not_active IP Right Cessation
- 2004-04-23 EC EC2004005080A patent/ECSP045080A/es unknown
-
2009
- 2009-02-02 CY CY20091100116T patent/CY1110173T1/el unknown
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