DE60232956D1 - Verfahren zur behandlung von stressbedingten erkrankungen unter verwendung von glucocorticoid-rezepto-spezifischen antagonisten - Google Patents
Verfahren zur behandlung von stressbedingten erkrankungen unter verwendung von glucocorticoid-rezepto-spezifischen antagonistenInfo
- Publication number
- DE60232956D1 DE60232956D1 DE60232956T DE60232956T DE60232956D1 DE 60232956 D1 DE60232956 D1 DE 60232956D1 DE 60232956 T DE60232956 T DE 60232956T DE 60232956 T DE60232956 T DE 60232956T DE 60232956 D1 DE60232956 D1 DE 60232956D1
- Authority
- DE
- Germany
- Prior art keywords
- glucocorticoid
- receptor
- related diseases
- specific antagonists
- treating stress
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27852301P | 2001-03-23 | 2001-03-23 | |
| PCT/US2002/008622 WO2002076390A2 (en) | 2001-03-23 | 2002-03-19 | Methods for treating stress disorders using glucocorticoid receptor-specific antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60232956D1 true DE60232956D1 (de) | 2009-08-27 |
Family
ID=23065304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60232956T Expired - Lifetime DE60232956D1 (de) | 2001-03-23 | 2002-03-19 | Verfahren zur behandlung von stressbedingten erkrankungen unter verwendung von glucocorticoid-rezepto-spezifischen antagonisten |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6964953B2 (de) |
| EP (1) | EP1370268B1 (de) |
| JP (2) | JP2004525135A (de) |
| KR (1) | KR100895662B1 (de) |
| CN (2) | CN1556709A (de) |
| AU (1) | AU2002255845B2 (de) |
| CA (1) | CA2440605C (de) |
| DE (1) | DE60232956D1 (de) |
| DK (1) | DK1370268T3 (de) |
| ES (1) | ES2326364T3 (de) |
| IL (2) | IL157770A0 (de) |
| NO (1) | NO334745B1 (de) |
| NZ (1) | NZ528147A (de) |
| PT (1) | PT1370268E (de) |
| WO (1) | WO2002076390A2 (de) |
| ZA (1) | ZA200307066B (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7163934B2 (en) | 2001-05-04 | 2007-01-16 | Corcept Therapeutics, Inc. | Methods for treating delirium glucocorticoid receptor-specific antagonists |
| JP2005512949A (ja) * | 2001-05-04 | 2005-05-12 | コーセプト セラピューティクス， インコーポレイテッド | グルココルチコイドレセプターに特異的なアンタゴニストを使用して、せん妄を処置する方法 |
| ES2319563T3 (es) * | 2001-10-26 | 2009-05-08 | N.V. Organon | Uso de (11beta, 17beta)-11-(1.3-benzodioxol-5-il)-17-hidroxi-17-(1-propinil)estra-4,9-dien-3-ona para el tratamiento del trastorno por depresion mayor. |
| EP1453495A2 (de) | 2001-11-23 | 2004-09-08 | Akzo Nobel N.V. | Verfahren zur behandlung schwerer depression unter verwendung von glucocorticoid-rezeptor-antagonisten |
| EP1643946A2 (de) * | 2003-06-20 | 2006-04-12 | Viral Genomix, Inc. | Zusammensetzungen und verfahren zur behandlung von hiv |
| US8097606B2 (en) | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
| US20050080061A1 (en) * | 2003-07-23 | 2005-04-14 | Corcept Therapeutics, Inc. | Antiglucocorticoid therapy for the prevention of neurological damage in premature infants |
| GB0400031D0 (en) | 2004-01-03 | 2004-02-04 | Univ Sheffield | Depression treatment |
| EP2527447A1 (de) | 2004-06-03 | 2012-11-28 | Athlomics Pty Ltd | Mittel und Verfahren zur Diagnose von Stress |
| WO2008137270A1 (en) * | 2007-05-04 | 2008-11-13 | H. Lundbeck A/S | Methods of diagnosing and monitoring of npy y5 based disorders |
| US8598149B2 (en) * | 2007-08-30 | 2013-12-03 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels in plasma serum of patients suffering from mental disorders treatable with glucocorticoid receptor antagonists |
| EP2576582B1 (de) * | 2010-05-26 | 2019-09-18 | Corcept Therapeutics, Inc. | Behandlung von muskeldystrophie |
| US9314473B2 (en) * | 2011-02-03 | 2016-04-19 | Pop Test Oncology Limited Liability Company | System and method for diagnosis and treatment |
| US8658128B2 (en) | 2011-02-03 | 2014-02-25 | Pop Test Cortisol Llc | System and method for diagnosis and treatment |
| US10500216B2 (en) | 2011-11-18 | 2019-12-10 | Corcept Therapeutics, Inc. | Optimizing mifepristone absorption |
| US9943526B2 (en) | 2015-04-21 | 2018-04-17 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels for cushing's patients |
| EP3231421A1 (de) * | 2016-04-11 | 2017-10-18 | Greenaltech, S.L. | Verwendungen eines carotenoids bei der behandlung oder prävention von durch stress verursachten störungen |
| JP2020510011A (ja) * | 2017-03-09 | 2020-04-02 | コーセプト セラピューティクス， インコーポレイテッド | カテコールアミン分泌腫瘍の処置における糖質コルチイド受容体モジレータの使用 |
| US20220072009A1 (en) * | 2018-12-28 | 2022-03-10 | Panda Consulting Llc | Short-acting selective glucocorticoid receptor modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1261165B (it) * | 1993-01-25 | 1996-05-09 | Polifarma Spa | Agente attivo per ridurre il livello ematico di glucocorticoidi e prevenire disturbi cerebrali da stress e senilita'. |
| CN1528315A (zh) * | 1997-10-06 | 2004-09-15 | ������˹̹�������ѧ�й�ίԱ�� | 治疗糖皮质素功能失调相关性精神病的方法 |
| NZ334627A (en) * | 1999-03-12 | 2002-07-26 | Horticulture & Food Res Inst | A therapeutic composition containing a therapeutic agent such as an anthelmintic and an antistress agent such as metyrapone or a nitric oxide promoter for increasing efficacy of therapeutic agents and animal growth |
| US6620802B1 (en) | 1999-11-23 | 2003-09-16 | Corcept Therapeutics, Inc. | Methods of treating mild cognitive impairment using a glucocorticoid-specific receptor antagonist |
| EP1127882A1 (de) * | 2000-01-25 | 2001-08-29 | Pfizer Products Inc. | Tetrazolverbindungen als Thyroid-Rezeptor-Liganden |
| IL142707A0 (en) | 2000-04-27 | 2002-03-10 | Pfizer Prod Inc | Methods of treating obesity using a neurotensin receptor ligand |
-
2002
- 2002-03-19 US US10/102,448 patent/US6964953B2/en not_active Expired - Lifetime
- 2002-03-19 PT PT02725270T patent/PT1370268E/pt unknown
- 2002-03-19 NZ NZ528147A patent/NZ528147A/en not_active IP Right Cessation
- 2002-03-19 CA CA2440605A patent/CA2440605C/en not_active Expired - Lifetime
- 2002-03-19 WO PCT/US2002/008622 patent/WO2002076390A2/en active IP Right Grant
- 2002-03-19 DE DE60232956T patent/DE60232956D1/de not_active Expired - Lifetime
- 2002-03-19 EP EP02725270A patent/EP1370268B1/de not_active Expired - Lifetime
- 2002-03-19 JP JP2002574906A patent/JP2004525135A/ja active Pending
- 2002-03-19 KR KR1020037012301A patent/KR100895662B1/ko active IP Right Grant
- 2002-03-19 DK DK02725270T patent/DK1370268T3/da active
- 2002-03-19 IL IL15777002A patent/IL157770A0/xx unknown
- 2002-03-19 CN CNA028071263A patent/CN1556709A/zh active Pending
- 2002-03-19 CN CNA2005101082508A patent/CN1820756A/zh active Pending
- 2002-03-19 AU AU2002255845A patent/AU2002255845B2/en not_active Ceased
- 2002-03-19 ES ES02725270T patent/ES2326364T3/es not_active Expired - Lifetime
-
2003
- 2003-09-04 IL IL157770A patent/IL157770A/en unknown
- 2003-09-10 ZA ZA200307066A patent/ZA200307066B/en unknown
- 2003-09-23 NO NO20034232A patent/NO334745B1/no not_active IP Right Cessation
-
2009
- 2009-02-03 JP JP2009023152A patent/JP2009102412A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002255845B2 (en) | 2006-11-23 |
| IL157770A0 (en) | 2004-03-28 |
| CA2440605C (en) | 2012-01-10 |
| EP1370268A2 (de) | 2003-12-17 |
| CN1556709A (zh) | 2004-12-22 |
| KR100895662B1 (ko) | 2009-05-07 |
| EP1370268B1 (de) | 2009-07-15 |
| JP2004525135A (ja) | 2004-08-19 |
| PT1370268E (pt) | 2009-08-26 |
| ES2326364T3 (es) | 2009-10-08 |
| EP1370268A4 (de) | 2005-02-09 |
| CA2440605A1 (en) | 2002-10-03 |
| WO2002076390A2 (en) | 2002-10-03 |
| ZA200307066B (en) | 2004-09-10 |
| NO20034232D0 (no) | 2003-09-23 |
| KR20030093266A (ko) | 2003-12-06 |
| WO2002076390A3 (en) | 2003-05-22 |
| NO334745B1 (no) | 2014-05-19 |
| NZ528147A (en) | 2005-06-24 |
| IL157770A (en) | 2010-11-30 |
| JP2009102412A (ja) | 2009-05-14 |
| CN1820756A (zh) | 2006-08-23 |
| DK1370268T3 (da) | 2009-09-14 |
| NO20034232L (no) | 2003-11-21 |
| US20020169152A1 (en) | 2002-11-14 |
| US6964953B2 (en) | 2005-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |