NO20035486D0 - Benzodiazepinderivater og deres anvendelse som AMPA- reseptorstimulatorer - Google Patents

Benzodiazepinderivater og deres anvendelse som AMPA- reseptorstimulatorer

Info

Publication number
NO20035486D0
NO20035486D0 NO20035486A NO20035486A NO20035486D0 NO 20035486 D0 NO20035486 D0 NO 20035486D0 NO 20035486 A NO20035486 A NO 20035486A NO 20035486 A NO20035486 A NO 20035486A NO 20035486 D0 NO20035486 D0 NO 20035486D0
Authority
NO
Norway
Prior art keywords
ampa receptor
benzodiazepine derivatives
receptor stimulators
stimulators
benzodiazepine
Prior art date
Application number
NO20035486A
Other languages
English (en)
Other versions
NO328705B1 (no
Inventor
Simon James Anthony Grove
Mingqiang Zhang
Mohammad Shahid
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of NO20035486D0 publication Critical patent/NO20035486D0/no
Publication of NO328705B1 publication Critical patent/NO328705B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D515/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • A61P25/12Antiepileptics; Anticonvulsants for grand-mal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20035486A 2001-06-11 2003-12-10 Benzodiazepinderivater og deres anvendelse som AMPA-reseptorstimulatorer NO328705B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01202215 2001-06-11
PCT/EP2002/006185 WO2002100865A1 (en) 2001-06-11 2002-06-05 Benzoxazepine derivatives and their use as ampa receptor stimulators

Publications (2)

Publication Number Publication Date
NO20035486D0 true NO20035486D0 (no) 2003-12-10
NO328705B1 NO328705B1 (no) 2010-05-03

Family

ID=8180450

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20035486A NO328705B1 (no) 2001-06-11 2003-12-10 Benzodiazepinderivater og deres anvendelse som AMPA-reseptorstimulatorer

Country Status (30)

Country Link
US (2) US7307073B2 (no)
EP (1) EP1399450B1 (no)
JP (1) JP4435561B2 (no)
KR (1) KR100863255B1 (no)
CN (1) CN1257908C (no)
AR (1) AR036092A1 (no)
AT (1) ATE389659T1 (no)
AU (1) AU2002314144B2 (no)
BR (1) BR0210222A (no)
CA (1) CA2450274C (no)
CO (1) CO5550447A2 (no)
CZ (1) CZ300052B6 (no)
DE (1) DE60225689T2 (no)
EC (1) ECSP034891A (no)
ES (1) ES2301651T3 (no)
HK (1) HK1061858A1 (no)
HR (1) HRP20031007A2 (no)
HU (1) HUP0400154A3 (no)
IL (2) IL158905A0 (no)
IS (1) IS2526B (no)
MX (1) MXPA03011563A (no)
NO (1) NO328705B1 (no)
NZ (1) NZ529670A (no)
PE (1) PE20030097A1 (no)
PL (1) PL366721A1 (no)
RU (1) RU2279434C2 (no)
SK (1) SK287150B6 (no)
TW (1) TWI232863B (no)
WO (1) WO2002100865A1 (no)
ZA (1) ZA200309382B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL158928A0 (en) 2001-06-14 2004-05-12 Akzo Nobel Nv (PYRIDO/THIENO)-[f]-OXAZEPIN-5-ONE DERIVATIVES
US20110218190A1 (en) * 2008-11-10 2011-09-08 The Regents Of The University Of California Therapeutic uses of ampa receptor modulators for treatment of motor dysfunction
ES2570569T3 (es) * 2009-09-28 2016-05-19 Hoffmann La Roche Compuestos de benzoxazepina como inhibidores de la PI3K y métodos de uso
FR2964969B1 (fr) 2010-09-16 2012-08-24 Servier Lab Nouveaux derives dihydrobenzoxathiazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN105579575A (zh) 2013-06-13 2016-05-11 维罗技术有限责任公司 用于治疗代谢失调的组合物和方法
US10821103B2 (en) 2016-11-07 2020-11-03 Arbutus Biopharma Corporation Substituted pyridinone-containing trycyclic compounds, and methods using same
TWI801517B (zh) 2018-03-12 2023-05-11 加拿大商愛彼特生物製藥公司 經取代的2-吡啶酮三環化合物、其類似物及其使用方法
TW202010499A (zh) 2018-04-12 2020-03-16 加拿大商愛彼特生物製藥公司 經取代的吡啶酮之三環化合物的製備方法
EP4121072A1 (en) * 2020-03-20 2023-01-25 Amathus Therapeutics, Inc. Cyclic sulfonamide derivatives as trap1 modulators and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1238719A (no) 1968-11-01 1971-07-07
CA2450801C (en) 1992-07-24 2009-11-17 The Regent Of The University Of California Drugs that enhance synaptic responses mediated by ampa receptors
DE59607274D1 (de) 1995-01-06 2001-08-16 Hoffmann La Roche Hydroxymethyl-imidazodiazepine und deren ester
US5650409A (en) * 1995-06-02 1997-07-22 Cortex Pharmaceuticals, Inc. Benzoyl piperidines/pyrrolidines for enhancing synaptic response
US5736543A (en) * 1996-04-03 1998-04-07 The Regents Of The University Of California Benzoxazines for enhancing synaptic response
DE69831446T2 (de) 1997-06-09 2006-06-14 Pfizer Prod Inc Chinazolin-4-on AMPA Antagonisten
US5985871A (en) * 1997-12-24 1999-11-16 Cortex Pharmaceuticals, Inc. Benzoxazine compounds for enhancing synaptic response
EE200000468A (et) * 1998-02-18 2002-04-15 Neurosearch A/S Ühendid, nende kasutamine ja farmatseutiline kompositsioon
US6124278A (en) 1998-04-03 2000-09-26 The Regents Of The University Of California Acylbenzoxazines for enhancing synaptic response

Also Published As

Publication number Publication date
MXPA03011563A (es) 2004-03-18
IS2526B (is) 2009-07-15
US7307073B2 (en) 2007-12-11
CN1257908C (zh) 2006-05-31
ES2301651T3 (es) 2008-07-01
CZ20033376A3 (en) 2004-04-14
RU2279434C2 (ru) 2006-07-10
HRP20031007A2 (en) 2005-10-31
CA2450274A1 (en) 2002-12-19
DE60225689T2 (de) 2008-07-17
WO2002100865A1 (en) 2002-12-19
EP1399450B1 (en) 2008-03-19
DE60225689D1 (de) 2008-04-30
RU2004100310A (ru) 2005-06-10
CZ300052B6 (cs) 2009-01-21
JP4435561B2 (ja) 2010-03-17
HUP0400154A3 (en) 2007-05-02
NZ529670A (en) 2006-02-24
KR100863255B1 (ko) 2008-10-15
SK15182003A3 (sk) 2004-05-04
JP2004533466A (ja) 2004-11-04
IL158905A (en) 2008-12-29
CA2450274C (en) 2010-12-21
BR0210222A (pt) 2004-04-13
CN1514835A (zh) 2004-07-21
CO5550447A2 (es) 2005-08-31
HUP0400154A2 (hu) 2004-07-28
PL366721A1 (en) 2005-02-07
HK1061858A1 (en) 2004-10-08
ATE389659T1 (de) 2008-04-15
PE20030097A1 (es) 2003-02-08
ZA200309382B (en) 2005-03-02
ECSP034891A (es) 2004-01-28
TWI232863B (en) 2005-05-21
IL158905A0 (en) 2004-05-12
AU2002314144B2 (en) 2008-01-31
US20040171605A1 (en) 2004-09-02
KR20040006030A (ko) 2004-01-16
NO328705B1 (no) 2010-05-03
IS7036A (is) 2003-11-13
SK287150B6 (sk) 2010-01-07
EP1399450A1 (en) 2004-03-24
US20080139529A1 (en) 2008-06-12
US7504390B2 (en) 2009-03-17
AR036092A1 (es) 2004-08-11

Similar Documents

Publication Publication Date Title
DK1204649T3 (da) Arylmethylcarbonylaminothiazolderivater og deres anvendelse som antitumormidler
NO20032277D0 (no) Aminotiazoler og deres anvendelse som adenosinreseptorantagonister
NO20020684D0 (no) Aminopyrazolderivater, fremgangsmåte for deres fremstilling og deres anvendelse som antitumormidler
NO20021329D0 (no) Kinaseinhibitorer som terapeutiske midler
DK1419152T3 (da) HIV-hæmmende pyrimidin-derivater
DK1394150T3 (da) 4-phenylpyridinderivater og deres anvendelse som NK-1-receptorantagonister
NO20024742D0 (no) Heterocykliske forbindelser, deres fremstilling og anvendelse
DK1177178T3 (da) Heterocyclisk substituerede benzimidazoler, deres fremstilling og anvendelse
NO20034439D0 (no) Benzamidinderivater
DK1478629T3 (da) N-aryl-2-oxazolidinon-5-carboxamider og deres derivater og deres anvendelse som antibakterielle midler
NO20053569D0 (no) Substituerte 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazinderivater og deres anvendelse som nevrokininantagonister
DK1083171T3 (da) Pyrazolinderivater, deres fremstilling og anvendelse som medikamenter
DK1095025T3 (da) Benzimidazoler, deres fremstilling og deres anvendelse som lægemidler
NO20025357D0 (no) Antranylamider og deres anvendelse som legemidler
NO20041008L (no) Karbazolderivater og anvendelse derav som NPY5 reseptor antagonister
NO20025150D0 (no) 2-acylindolderivater og deres anvendelse som antitumormidler
DK1387838T3 (da) Cyanoanthranylamid-derivater og deres anvendelse som lægemidler
DK1525193T3 (da) Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse
DK1043307T3 (da) 3-amino-3-arylpropan-1-ol-derivater, deres fremstilling og anvendelse
NO20034434L (no) Indolinoner substituert i 6-stilling og deres anvendelse som kinase-inhibitorer
DE60213851D1 (de) Ringannelierte pyrazolderivate
NO20004144D0 (no) Heterocykliske forbindelser, deres fremstilling og anvendelse som takykinin reseptor antagonister
NO20035486D0 (no) Benzodiazepinderivater og deres anvendelse som AMPA- reseptorstimulatorer
NO20043799L (no) 2-oksasolaminer og deres anvendelse som 5-HT2B reseptor antagonister
NO20042684L (no) Benzotia(dia)zinderivater og deres anvendelse som ampa-modulatorer

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees