NO20035010L - Fremgangsmåter og blandinger for analysering av proteiner - Google Patents

Fremgangsmåter og blandinger for analysering av proteiner

Info

Publication number
NO20035010L
NO20035010L NO20035010A NO20035010A NO20035010L NO 20035010 L NO20035010 L NO 20035010L NO 20035010 A NO20035010 A NO 20035010A NO 20035010 A NO20035010 A NO 20035010A NO 20035010 L NO20035010 L NO 20035010L
Authority
NO
Norway
Prior art keywords
blends
proteins
analysis
methods
Prior art date
Application number
NO20035010A
Other languages
English (en)
Norwegian (no)
Other versions
NO20035010D0 (no
Inventor
Hossein Salimi-Moosavi
Sharat Singh
Syed Hasan Tahir
Gerald J Wallweber
Hrair Kirakossian
Tracy J Matray
Vincent S Hernandez
Original Assignee
Aclara Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aclara Biosciences Inc filed Critical Aclara Biosciences Inc
Publication of NO20035010D0 publication Critical patent/NO20035010D0/no
Publication of NO20035010L publication Critical patent/NO20035010L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G01N33/561—Immunoelectrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
NO20035010A 2001-05-21 2003-11-11 Fremgangsmåter og blandinger for analysering av proteiner NO20035010L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29254801P 2001-05-21 2001-05-21
US33490101P 2001-10-24 2001-10-24
PCT/US2002/016098 WO2002095356A2 (en) 2001-05-21 2002-05-21 Methods and compositions for analyzing proteins

Publications (2)

Publication Number Publication Date
NO20035010D0 NO20035010D0 (no) 2003-11-11
NO20035010L true NO20035010L (no) 2003-11-11

Family

ID=26967405

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20035010A NO20035010L (no) 2001-05-21 2003-11-11 Fremgangsmåter og blandinger for analysering av proteiner

Country Status (11)

Country Link
US (4) US7255999B2 (de)
EP (1) EP1506399A2 (de)
JP (1) JP2005505749A (de)
KR (1) KR20040082273A (de)
CN (1) CN1559006A (de)
AU (1) AU2002310012A1 (de)
CA (1) CA2445053A1 (de)
CZ (1) CZ20033143A3 (de)
NO (1) NO20035010L (de)
PL (1) PL373962A1 (de)
WO (1) WO2002095356A2 (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL373962A1 (en) 2001-05-21 2005-09-19 Aclara Biosciences, Inc. Methods and compositions for analyzing proteins
JP2005509859A (ja) * 2001-11-09 2005-04-14 アクララ バイオサイエンシーズ， インコーポレイテッド タグ標識された微粒子組成物および方法
US20040229380A1 (en) * 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB heterodimers as biomarkers
US20040229294A1 (en) 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB surface receptor complexes as biomarkers
WO2004011128A1 (en) * 2002-07-26 2004-02-05 Aclara Biosciences, Inc. Methods and compositions for screening cell binding molecules
US20040091850A1 (en) * 2002-11-08 2004-05-13 Travis Boone Single cell analysis of membrane molecules
JP2007504482A (ja) * 2003-01-17 2007-03-01 アクララ バイオサイエンシーズ， インコーポレイテッド タグ付加分子ライブラリーを使用した受容体の脱オーファン化
US7029855B1 (en) * 2003-01-28 2006-04-18 Proteomyx Inc. Radioactive multiplexing analytical methods for biomarkers discovery
AU2004225439A1 (en) 2003-04-01 2004-10-14 Monogram Biosciences, Inc. Intracellular complexes as biomarkers
US7402398B2 (en) * 2003-07-17 2008-07-22 Monogram Biosciences, Inc. Measuring receptor homodimerization
NZ545873A (en) 2003-08-11 2009-05-31 Monogram Biosciences Inc Detecting and profiling molecular complexes
EP1689882B1 (de) * 2003-10-07 2014-11-26 TRAN, Nathaniel Tue Radioaktive multiplex-analyseverfahren
US7402399B2 (en) * 2003-10-14 2008-07-22 Monogram Biosciences, Inc. Receptor tyrosine kinase signaling pathway analysis for diagnosis and therapy
IL160869A0 (en) * 2004-03-15 2004-08-31 Dnr Imaging System Ltd Integrated system for real time gel electrophoresis running and documenting
JP4311319B2 (ja) * 2004-09-22 2009-08-12 ウシオ電機株式会社 ショートアーク型放電ランプ
WO2006042161A2 (en) 2004-10-07 2006-04-20 E.I. Dupont De Nemours And Company Polysaccharide-based polymer tissue adhesive for medical use
US20060100787A1 (en) * 2004-11-09 2006-05-11 Intel Corporation Synthesis of nanocodes, and imaging using scanning probe microscopy
US20060204999A1 (en) * 2005-03-14 2006-09-14 Stephen Macevicz Detecting molecular complexes
US20060211030A1 (en) * 2005-03-16 2006-09-21 Sydney Brenner Methods and compositions for assay readouts on multiple analytical platforms
US20060281104A1 (en) * 2005-06-13 2006-12-14 Macevicz Stephen C Leuco dye particles and uses thereof
JP4724816B2 (ja) * 2005-09-06 2011-07-13 シャープ株式会社 タンパク質の測定方法
US8357277B2 (en) 2007-11-27 2013-01-22 Laboratory Corp. of America Holdings Enhanced method for detecting and/or quantifying an analyte in a sample
WO2009110873A2 (en) * 2007-12-05 2009-09-11 The Gov. Of The Usa, As Represented By The Secretary Dept. Of Health & Human Services Improved viral protein quantification and vaccine quality control therewith
WO2009086197A1 (en) 2007-12-20 2009-07-09 Monogram Biosciences, Inc. Her-2 diagnostic methods
US20100015231A1 (en) * 2008-07-17 2010-01-21 E.I. Du Pont De Nemours And Company Low swell, long-lived hydrogel sealant
WO2010059279A2 (en) * 2008-11-19 2010-05-27 E. I. Du Pont De Nemours And Company Hydrogel tissue adhesive formed from aminated polysaccharide and aldehyde-functionalized multi-arm polyether
US8470542B2 (en) * 2008-12-01 2013-06-25 Laboratory Corporation Of America Holdings Methods and assays for measuring p95 and/or p95 complexes in a sample and antibodies specific for p95
US20100160960A1 (en) * 2008-12-19 2010-06-24 E. I. Du Pont De Nemours And Company Hydrogel tissue adhesive having increased degradation time
CA2749817A1 (en) * 2009-01-15 2010-07-22 Laboratory Corporation Of America Holdings Methods of determining patient response by measurement of her-2 expression
CA2749846C (en) 2009-01-15 2018-08-07 Laboratory Corporation Of America Holdings Methods of determining patient response by measurement of her-3
US20120094955A1 (en) * 2009-04-09 2012-04-19 Actamax Surgical Materials Llc Method of dissolving an oxidized polysaccharide in an aqueous solution
CN102438666A (zh) 2009-04-09 2012-05-02 阿克塔马克斯手术器材有限责任公司 降解时间缩短的水凝胶组织粘合剂
JP5872463B2 (ja) 2009-07-02 2016-03-01 アクタマックス サージカル マテリアルズ リミテッド ライアビリティカンパニー 医療用ヒドロゲル組織接着剤
US8796242B2 (en) 2009-07-02 2014-08-05 Actamax Surgical Materials, Llc Hydrogel tissue adhesive for medical use
CN103068853B (zh) * 2010-08-19 2016-08-10 Peg生物制药公司 协同性生物分子-聚合物轭合物
TW201302793A (zh) 2010-09-03 2013-01-16 Glaxo Group Ltd 新穎之抗原結合蛋白
WO2012168803A2 (en) 2011-06-07 2012-12-13 Koninklijke Philips Electronics N.V. Providing nucleotide sequence data
DE102011109063B3 (de) * 2011-07-28 2012-12-20 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Verfahren zum Nachweis von Biomolekülen
US10370409B2 (en) 2011-10-25 2019-08-06 The Scripps Research Institute Synthesis of libraries of peptide tertiary amides
JP5468056B2 (ja) * 2011-12-15 2014-04-09 富士フイルム株式会社 電気泳動組成物、マイクロカプセル、及び、電気泳動表示素子
US8921277B2 (en) * 2012-09-26 2014-12-30 Palo Alto Research Center Incorporated Multiplexed flow assay based on absorption-encoded micro beads
WO2014053479A1 (en) 2012-10-02 2014-04-10 Roche Diagnostics Gmbh Methods of specifically releasing a sub-group of objects
EP2981828A1 (de) 2013-04-05 2016-02-10 Laboratory Corporation of America Holdings Systeme und verfahren zur erleichterung der diagnose, prognose und behandlung von krebs auf basis der erkennung einer her3-aktivierung
EP3027659B1 (de) 2013-07-29 2020-12-09 Actamax Surgical Materials LLC Gewebeklebstoff mit niedriger schwellung und dichtungsmittelzusammensetzungen
EP3183243B1 (de) * 2014-08-20 2025-07-23 The Governing Council of the University of Toronto Organotellurverbindungen, zusammensetzungen und verfahren zur verwendung davon
EP3050886A1 (de) * 2015-02-02 2016-08-03 Bürkert Werke GmbH Fluoreszenzfarbstoffe und Farbstoffvorläufer
SG10202107055SA (en) 2015-07-17 2021-08-30 Nanostring Technologies Inc Simultaneous quantification of a plurality of proteins in a user-defined region of a cross-sectioned tissue
ES2975362T3 (es) 2015-07-17 2024-07-04 Nanostring Technologies Inc Cuantificación simultánea de la expresión génica en una región definida por el usuario de un tejido seccionado transversalmente
CA3016914C (en) 2016-03-15 2019-08-27 Laboratory Corporation Of America Holdings Methods of assessing protein interactions between cells
US9994713B2 (en) * 2016-03-28 2018-06-12 King Fahd University Of Petroleum And Minerals Fluorescent schiff base conjugate Cu(II) chemosensors and methods thereof
CN107462618B (zh) * 2016-06-03 2019-05-21 中国科学院生态环境研究中心 一种蛋白质O-GlcNAc糖基转移酶活性电化学传感检测方法
KR102406008B1 (ko) 2016-10-14 2022-06-07 창원대학교 산학협력단 전자전달해리(etd) 질량분석을 이용한 단백질의 정량분석법
KR102476709B1 (ko) 2016-11-21 2022-12-09 나노스트링 테크놀로지스, 인크. 화학적 조성물 및 이것을 사용하는 방법
CN109917120B (zh) * 2017-12-12 2022-10-28 清华大学 检测翻译后修饰蛋白质与其配体间相互作用的成套试剂
CN108387435B (zh) * 2018-01-30 2020-09-15 中国计量大学 一种痕量丝素蛋白富集方法
EP3752635B1 (de) 2018-02-12 2026-02-11 Bruker Spatial Biology, Inc. Verfahren zur detektion von gen- expression
MY202358A (en) * 2018-03-19 2024-04-24 Regeneron Pharma Microchip capillary electrophoresis assays and reagents
KR102893736B1 (ko) 2018-05-14 2025-11-28 브루커 스페이셜 바이올로지, 인크. 화학 조성물 및 이의 사용 방법
AU2021350473A1 (en) 2020-09-28 2023-04-27 Merus B.V. Method for detecting expression or clustering of cell surface moieties
CN113567520B (zh) * 2021-07-08 2024-06-07 西北农林科技大学 一种用于痕量蛋白分子精准检测的电化学传感方法
CN115144348B (zh) * 2022-07-06 2025-02-14 浙江伊利康生物技术有限公司 糖化白蛋白检测试剂盒、制备方法及其应用方法

Family Cites Families (138)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2153059A (en) * 1936-02-26 1939-04-04 Gen Aniline Works Inc Chromable dyestuffs of the triarylmethane series and process of preparing them
US2242572A (en) * 1939-06-21 1941-05-20 Gen Aniline & Film Corp Chromable dyestuffs of the triarylmethane series and a process of preparing them
US3932415A (en) * 1972-04-17 1976-01-13 Eastman Kodak Company Pyrylium dyes having a fused rigidized nitrogen-containing ring
US4331590A (en) 1978-03-13 1982-05-25 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled protein and polypeptide conjugates
FR2431581A1 (fr) 1978-07-18 1980-02-15 Soum Rene Systeme d'assemblage de planchers
US4230558A (en) 1978-10-02 1980-10-28 Coulter Electronics, Inc. Single drop separator
US4318846A (en) * 1979-09-07 1982-03-09 Syva Company Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers
US4458066A (en) * 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4973679A (en) * 1981-03-27 1990-11-27 University Patents, Inc. Process for oligonucleo tide synthesis using phosphormidite intermediates
US4415732A (en) * 1981-03-27 1983-11-15 University Patents, Inc. Phosphoramidite compounds and processes
US4650750A (en) 1982-02-01 1987-03-17 Giese Roger W Method of chemical analysis employing molecular release tag compounds
US5650270A (en) 1982-02-01 1997-07-22 Northeastern University Molecular analytical release tags and their use in chemical analysis
US4709016A (en) 1982-02-01 1987-11-24 Northeastern University Molecular analytical release tags and their use in chemical analysis
US5516931A (en) 1982-02-01 1996-05-14 Northeastern University Release tag compounds producing ketone signal groups
DE3329892A1 (de) * 1983-08-18 1985-03-07 Köster, Hubert, Prof. Dr., 2000 Hamburg Verfahren zur herstellung von oligonucleotiden
US4562248A (en) 1983-11-25 1985-12-31 Eastman Kodak Company Azo dyes from unsubstituted or substituted 3-amino-pyridine and aryl or heterocyclic couplers
GB8407736D0 (en) 1984-03-26 1984-05-02 Univ London Detecting specific polynucleotide sequences
US4675300A (en) 1985-09-18 1987-06-23 The Board Of Trustees Of The Leland Stanford Junior University Laser-excitation fluorescence detection electrokinetic separation
US4780421A (en) 1986-04-03 1988-10-25 Sclavo Inc. Cleavable labels for use in binding assays
FR2596761B1 (fr) 1986-04-08 1988-05-20 Commissariat Energie Atomique Derives de nucleosides et leur utilisation pour la synthese d'oligonucleotides
US4811218A (en) * 1986-06-02 1989-03-07 Applied Biosystems, Inc. Real time scanning electrophoresis apparatus for DNA sequencing
US5494793A (en) 1986-12-15 1996-02-27 British Technology Group Usa Inc. Monomeric phthalocyanine reagents
DE3821454A1 (de) * 1987-06-24 1989-02-09 Hitachi Ltd Verfahren zur aufbereitung gebrauchter elektrophorese-gele fuer die wiederverwendung
US4894348A (en) * 1987-07-01 1990-01-16 Ronald Robert C Fluorescein-conjugated proteins with enhanced fluorescence
US5057301A (en) * 1988-04-06 1991-10-15 Neorx Corporation Modified cellular substrates used as linkers for increased cell retention of diagnostic and therapeutic agents
JP2681061B2 (ja) 1988-06-08 1997-11-19 ロンドン・ダイアグノスティック・インコーポレーテッド 検出可能なシグナルのセンシタイザー誘導発生を利用したアッセイ
NL8801826A (nl) * 1988-07-19 1990-02-16 Tno Werkwijze voor het detecteren van mutaties in markergenen.
US4997928A (en) * 1988-09-15 1991-03-05 E. I. Du Pont De Nemours And Company Fluorescent reagents for the preparation of 5'-tagged oligonucleotides
US5571666A (en) 1988-10-28 1996-11-05 Oklahoma Medical Research Foundation Thiazine dyes used to inactivate HIV in biological fluids
US5064104A (en) * 1988-10-28 1991-11-12 Milancolimited, Inc. Apparatus for vending a product
US5254469A (en) 1989-09-12 1993-10-19 Eastman Kodak Company Oligonucleotide-enzyme conjugate that can be used as a probe in hybridization assays and polymerase chain reaction procedures
US5654442A (en) * 1989-11-14 1997-08-05 The Perkin-Elmer Corporation 4,7-dichlorofluorescein dyes as molecular probes
US5091652A (en) * 1990-01-12 1992-02-25 The Regents Of The University Of California Laser excited confocal microscope fluorescence scanner and method
US5274240A (en) 1990-01-12 1993-12-28 The Regents Of The University Of California Capillary array confocal fluorescence scanner and method
AU7302891A (en) * 1990-01-26 1991-08-21 La Jolla Cancer Research Foundation Polypeptides encoding transcriptional activators and uses thereof
IE66205B1 (en) 1990-06-14 1995-12-13 Paul A Bartlett Polypeptide analogs
US5650489A (en) 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
EP0484027B1 (de) 1990-11-02 1996-12-18 Zeneca Limited Polysubstituierte Phthalocyanine
US5578498A (en) 1991-05-22 1996-11-26 Behringwerke Ag Metal chelate containing compositions for use in chemiluminescent assays
US5340716A (en) 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5846717A (en) 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
ATE148889T1 (de) 1991-09-18 1997-02-15 Affymax Tech Nv Verfahren zur synthese der verschiedenen sammlungen von oligomeren
US5254468A (en) * 1991-10-31 1993-10-19 The University Of Toledo Bilayer pellet containing immobilized xylose isomerase and urease for the simultaneous isomerization and fermentation of xylose to ethanol
US5137609A (en) 1992-01-31 1992-08-11 Biometric Imaging Inc. Differential separation assay
US5843680A (en) 1992-01-31 1998-12-01 Biometric Imaging, Inc. Differential separation assay methods and test kits
JP3130629B2 (ja) 1992-03-13 2001-01-31 オリンパス光学工業株式会社 電気泳動における分画処理方法
EP0566751B1 (de) 1992-03-23 1996-01-10 F. Hoffmann-La Roche Ag Verfahren zum DNS-Nachweis
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
WO1993020236A1 (en) 1992-04-03 1993-10-14 Applied Biosystems, Inc. Probe composition and method
US5470705A (en) 1992-04-03 1995-11-28 Applied Biosystems, Inc. Probe composition containing a binding domain and polymer chain and methods of use
ATE162892T1 (de) 1992-07-31 1998-02-15 Behringwerke Ag Photoaktivierbare chemiluminizierende matrices
JP3207933B2 (ja) * 1992-09-09 2001-09-10 株式会社ヤトロン アクリジニウム誘導体の発光方法及びそれを用いた検査対象物質の検出方法
US5288514A (en) * 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US5958202A (en) 1992-09-14 1999-09-28 Perseptive Biosystems, Inc. Capillary electrophoresis enzyme immunoassay
US5565324A (en) 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US5721099A (en) 1992-10-01 1998-02-24 Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US5719028A (en) 1992-12-07 1998-02-17 Third Wave Technologies Inc. Cleavase fragment length polymorphism
US5374527A (en) 1993-01-21 1994-12-20 Applied Biosystems, Inc. High resolution DNA sequencing method using low viscosity medium
US5324401A (en) 1993-02-05 1994-06-28 Iowa State University Research Foundation, Inc. Multiplexed fluorescence detector system for capillary electrophoresis
US6087186A (en) 1993-07-16 2000-07-11 Irori Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
US5635602A (en) 1993-08-13 1997-06-03 The Regents Of The University Of California Design and synthesis of bispecific DNA-antibody conjugates
CA2170873A1 (en) 1993-09-03 1995-03-09 Dariush Davalian Fluorescent oxygen channeling immunoassays
CN1154640C (zh) 1993-10-01 2004-06-23 纽约市哥伦比亚大学理事 用标示物编码的多元组合化学库
US5503994A (en) * 1993-10-08 1996-04-02 The Board Of Trustees Of The Leland Stanford Junior University System for sample detection with compensation for difference in sensitivity to detection of components moving at different velocities
US5538848A (en) 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
AU1254295A (en) 1993-12-17 1995-07-03 Perkin-Elmer Corporation, The Uncharged polymers for separation of biomolecules by capillary electrophoresis
US5571680A (en) 1994-01-21 1996-11-05 Beckman Instruments, Inc. Homogeneous immunoassays and enzyme based assays of analytes using capillary electrophoresis
US5623055A (en) * 1994-01-28 1997-04-22 Prolinx, Inc. Phenylboronic acid complexes derived from aminosalicylic acid for bioconjugate preparation
US5543026A (en) * 1994-02-07 1996-08-06 The Perkin-Elmer Corporation Real-time scanning fluorescence electrophoresis apparatus for the analysis of polynucleotide fragments
US5851770A (en) 1994-04-25 1998-12-22 Variagenics, Inc. Detection of mismatches by resolvase cleavage using a magnetic bead support
US5986076A (en) 1994-05-11 1999-11-16 Trustees Of Boston University Photocleavable agents and conjugates for the detection and isolation of biomolecules
US6045995A (en) 1994-08-24 2000-04-04 Isis Pharmaceuticals, Inc. Capillary electrophoretic detection of nucleic acids
US5843666A (en) 1994-09-02 1998-12-01 Lumigen, Inc. Chemiluminescent detection methods using dual enzyer-labeled binding partners
US5691151A (en) 1994-10-07 1997-11-25 Regents Of University Of California Methods of screening for ulcerative colitis and crohn's disease by detecting VH3-15 autoantibody and panca
US5560811A (en) 1995-03-21 1996-10-01 Seurat Analytical Systems Incorporated Capillary electrophoresis apparatus and method
AU5438796A (en) 1995-04-06 1996-10-23 Arqule, Inc. Method for rapid purification, analysis and characterization of collections of chemical compounds
US5756726A (en) 1995-06-02 1998-05-26 Pharmacyclics, Inc. Methods of producing singlet oxygen using compounds having improved functionalization
US5843655A (en) 1995-09-18 1998-12-01 Affymetrix, Inc. Methods for testing oligonucleotide arrays
SE9503991D0 (sv) 1995-11-10 1995-11-10 Pharmacia Biotech Ab Method and apparatus for determining the existence of a mutation
US5846839A (en) 1995-12-22 1998-12-08 Glaxo Group Limited Methods for hard-tagging an encoded synthetic library
PT840804E (pt) 1996-01-23 2000-10-31 Qiagen Genomics Inc Metodos e composicoes para a analise de moleculas de acidos nocleicos usando tecnicas de separacao por dimensoes
US6312893B1 (en) 1996-01-23 2001-11-06 Qiagen Genomics, Inc. Methods and compositions for determining the sequence of nucleic acid molecules
BR9707060A (pt) 1996-01-23 1999-12-28 Rapigene Inc Métodos e composições para detectar o ligamento de par ligante usando indicador não-fluorescente.
US6027890A (en) 1996-01-23 2000-02-22 Rapigene, Inc. Methods and compositions for enhancing sensitivity in the analysis of biological-based assays
US5804400A (en) 1996-02-05 1998-09-08 Igen International, Inc. Electrochemiluminescent assay
US6090947A (en) 1996-02-26 2000-07-18 California Institute Of Technology Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
US5863727A (en) 1996-05-03 1999-01-26 The Perkin-Elmer Corporation Energy transfer dyes with enhanced fluorescence
US5945526A (en) * 1996-05-03 1999-08-31 Perkin-Elmer Corporation Energy transfer dyes with enhanced fluorescence
US5800996A (en) * 1996-05-03 1998-09-01 The Perkin Elmer Corporation Energy transfer dyes with enchanced fluorescence
US5811239A (en) 1996-05-13 1998-09-22 Frayne Consultants Method for single base-pair DNA sequence variation detection
EP0918845A4 (de) 1996-07-08 2000-08-30 Burstein Lab Inc Spaltbare signalelementvorrichtung und verfahren
US6780982B2 (en) 1996-07-12 2004-08-24 Third Wave Technologies, Inc. Charge tags and the separation of nucleic acid molecules
US5998140A (en) 1996-07-31 1999-12-07 The Scripps Research Institute Complex formation between dsDNA and oligomer of cyclic heterocycles
US5831046A (en) * 1996-08-05 1998-11-03 Prolinx, Incorporated Boronic acid-contaning nucleic acid monomers
US6045676A (en) 1996-08-26 2000-04-04 The Board Of Regents Of The University Of California Electrochemical detector integrated on microfabricated capilliary electrophoresis chips
US5763602A (en) 1996-10-01 1998-06-09 Li; Ying-Syi Methods of syntheses of phthalocyanine compounds
FI963989L (fi) 1996-10-04 1998-04-05 Wallac Oy Homogeenisiä määritysmenetelmiä, jotka perustuvat luminesenssienergiasiirtoon
US5894878A (en) 1996-10-04 1999-04-20 Morgan; Spencer T. Protective and decorative computer cover
US6245937B1 (en) * 1996-11-29 2001-06-12 Dupont Pharmaceuticals Research Laboratories, Inc. Liquid phase parallel synthesis of chemical libraries
US5856107A (en) 1997-02-04 1999-01-05 Trega Biosciences, Inc. Combinatorial libraries of imidazol-pyrido-indole and imidazol-pyrido-benzothiophene derivatives, methods of making the libraries and compounds therein
AU738237B2 (en) 1997-07-22 2001-09-13 Qiagen Genomics, Inc. Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
EP1012342A4 (de) 1997-09-10 2004-07-21 Univ Maryland Verfahren zur amplifizierung von dna- sowie rna-produkten, ausgehend von spaltstücken aufgrund von fehlbasenpaarungen
US6008379A (en) 1997-10-01 1999-12-28 The Perkin-Elmer Corporation Aromatic-substituted xanthene dyes
US5952654A (en) 1997-10-29 1999-09-14 Northeastern University Field-release mass spectrometry
US6562567B2 (en) * 1998-01-27 2003-05-13 California Institute Of Technology Method of detecting a nucleic acid
AU2679899A (en) 1998-02-18 1999-09-06 Dade Behring Inc. Chemiluminescent compositions for use in detection of multiple analytes
US6740497B2 (en) 1998-03-06 2004-05-25 The Regents Of The University Of California Method and apparatus for detecting cancerous cells using molecules that change electrophoretic mobility
US6335201B1 (en) 1998-03-06 2002-01-01 The Regents Of The University Of California Method and apparatus for detecting enzymatic activity using molecules that change electrophoretic mobility
WO1999046574A2 (en) * 1998-03-11 1999-09-16 The Wistar Institute Antibodies for assessing protein post-translational modification status and methods of making and using the same
DE69940970D1 (de) 1998-03-25 2009-07-23 Olink Ab Rolling circle replikation von padlock-sonden
GB9812596D0 (en) 1998-06-11 1998-08-12 Amersham Pharm Biotech Uk Ltd Energy transfer assay method
US6017769A (en) * 1998-06-17 2000-01-25 Lumigen, Inc. Non-enzymatic methods of generating chemiluminescence from acridan alkenes
US6821402B1 (en) 1998-09-16 2004-11-23 Applera Corporation Spectral calibration of fluorescent polynucleotide separation apparatus
US6013783A (en) * 1999-03-19 2000-01-11 Prolinx Incorporated Boronic acid containing oligonucleotides and polynucleotides
AU3519900A (en) 1999-03-19 2000-10-09 Aclara Biosciences, Inc. Methods for single nucleotide polymorphism detection
US6627400B1 (en) * 1999-04-30 2003-09-30 Aclara Biosciences, Inc. Multiplexed measurement of membrane protein populations
US6322980B1 (en) 1999-04-30 2001-11-27 Aclara Biosciences, Inc. Single nucleotide detection using degradation of a fluorescent sequence
US6649351B2 (en) * 1999-04-30 2003-11-18 Aclara Biosciences, Inc. Methods for detecting a plurality of analytes by mass spectrometry
US20020142329A1 (en) * 1999-04-30 2002-10-03 Aclara Biosciences, Inc. Compositions and methods employing cleavable electrophoretic tag reagents
US6673550B2 (en) * 1999-04-30 2004-01-06 Aclara Biosciences, Inc. Electrophoretic tag reagents comprising fluorescent compounds
US6142162A (en) 1999-06-18 2000-11-07 Odoreyes Technology, Inc. System and method for odorizing natural gas
US6331530B1 (en) 1999-07-13 2001-12-18 The Trustees Of Columbia University In The City Of New York Hydrophilic carrier for photosensitizers that cleaves when they catalyze the formation of singlet oxygen
US6191278B1 (en) * 1999-11-03 2001-02-20 Pe Corporation Water-soluble rhodamine dyes and conjugates thereof
US6372907B1 (en) * 1999-11-03 2002-04-16 Apptera Corporation Water-soluble rhodamine dye peptide conjugates
US7306904B2 (en) 2000-02-18 2007-12-11 Olink Ab Methods and kits for proximity probing
US6660229B2 (en) * 2000-06-13 2003-12-09 The Trustees Of Boston University Use of nucleotide analogs in the analysis of oligonucleotide mixtures and in highly multiplexed nucleic acid sequencing
WO2002029109A2 (en) 2000-10-05 2002-04-11 Aclara Biosciences, Inc. Multiplexed differential displacement for nucleic acid determinations
EP1317464B1 (de) 2000-10-11 2009-05-13 Applera Corporation Fluoreszierende nukleobasekonjugate mit anionische linker
US6468338B1 (en) * 2000-10-12 2002-10-22 Eastman Kodak Company Dye for ink jet ink
US6743905B2 (en) 2001-04-16 2004-06-01 Applera Corporation Mobility-modified nucleobase polymers and methods of using same
AU2002305658A1 (en) * 2001-05-21 2002-12-03 Aclara Biosciences, Inc. Analyzing phosphorylated proteins
PL373962A1 (en) * 2001-05-21 2005-09-19 Aclara Biosciences, Inc. Methods and compositions for analyzing proteins
WO2002097112A2 (en) 2001-05-26 2002-12-05 Aclara Biosciences, Inc. Catalytic amplification of multiplexed assay signals
US6949347B2 (en) 2002-03-05 2005-09-27 Aclara Biosciences, Inc. Multiplex analysis using membrane-bound sensitizers
US20040229380A1 (en) 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB heterodimers as biomarkers
PL374875A1 (en) 2002-07-25 2005-11-14 Aclara Biosciences, Inc. Detecting receptor oligomerization
AU2003249050A1 (en) * 2002-07-26 2004-02-16 Monogram Biosciences, Inc. Lipophilic electrophoretic probes

Also Published As

Publication number Publication date
AU2002310012A1 (en) 2002-12-03
PL373962A1 (en) 2005-09-19
US20030013126A1 (en) 2003-01-16
WO2002095356A2 (en) 2002-11-28
JP2005505749A (ja) 2005-02-24
US9110075B2 (en) 2015-08-18
US9939447B2 (en) 2018-04-10
US20080311674A1 (en) 2008-12-18
NO20035010D0 (no) 2003-11-11
US7255999B2 (en) 2007-08-14
CA2445053A1 (en) 2002-11-28
EP1506399A2 (de) 2005-02-16
CZ20033143A3 (en) 2004-04-14
US20160069893A1 (en) 2016-03-10
WO2002095356A3 (en) 2004-12-23
CN1559006A (zh) 2004-12-29
US20120088307A1 (en) 2012-04-12
KR20040082273A (ko) 2004-09-24

Similar Documents

Publication Publication Date Title
NO20035010D0 (no) Fremgangsmåter og blandinger for analysering av proteiner
NO20033387D0 (no) Modifiserte antistoffer og fremgangsmåter for anvendelse
NO20025488L (no) Stabiliserte tetrasoliumreagenssammensetninger og fremgangsmater for deres anvendelse
NO20025489D0 (no) Stabiliserte tetrasolium-fenasin-reagens-sammensetninger og fremgangsmÕter for deres anvendelse
IL228034A0 (en) Formulations with a high concentration of antibodies and proteins
DK1390389T3 (da) Cripto-blokerende antistoffer og anvendelser deraf
FR14C0007I2 (fr) Remodelage et glycoconjugaison de peptides
HUP0501021A3 (en) Methods and compositions for analyzing proteins
NO20033854L (no) N-but-3-enyl-norbuprenorfin og fremgangsmåter for anvendelse
DK1523243T3 (da) Mælkeproteinisolat og metode til fremstilling af samme
EP1578917A4 (de) Multimere proteine und verfahren zu deren herstellung und verwendung
NO20011026D0 (no) Matvare og fremgangsmÕte for fremstilling derav
NO20033506D0 (no) Parasittdrepende preparater og fremgangsmåter for anvendelse
NO20030843D0 (no) Anordning og fremgangsmåte for kultivering
NO20010824D0 (no) Diagnostisk analytisk metode og kit
NO20010823D0 (no) Diagnostisk analytisk metode og kit
NO20010706D0 (no) Diagnostisk analytisk metode og kit
NO20010707D0 (no) Diagnostisk analytisk metode og kit
NO20010822D0 (no) Diagnostisk analytisk metode og kit
NO20031847L (no) Sammensetninger og fremgangsmåter for oppdagelse og seleksjon av biologiskinformasjon
GB0223607D0 (en) Testing of samples
NO20030363D0 (no) Triggerpunktbehandler og fremgangsmåte for bruk av samme
FI20030654A0 (fi) Näytteenotin ja menetelmä näytteen ottamiseksi
SI1610820T1 (sl) Visokokoncentrirane formulacije protitelesa in proteinov
SE0001979D0 (sv) Protein and method using said protein

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application