NO20034863L - Deutererte 3-piperidinopropiofenon så vel som legemidler som inneholder disse forbindelser - Google Patents
Deutererte 3-piperidinopropiofenon så vel som legemidler som inneholder disse forbindelserInfo
- Publication number
- NO20034863L NO20034863L NO20034863A NO20034863A NO20034863L NO 20034863 L NO20034863 L NO 20034863L NO 20034863 A NO20034863 A NO 20034863A NO 20034863 A NO20034863 A NO 20034863A NO 20034863 L NO20034863 L NO 20034863L
- Authority
- NO
- Norway
- Prior art keywords
- deuterated
- well
- piperidinopropiophenone
- compounds
- piperidinopropiophenones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10123129A DE10123129A1 (de) | 2001-05-02 | 2001-05-02 | Deuterierte 3-Piperidinopropiophenone sowie diese Verbindungen enthaltende Arzneimittel |
| PCT/DE2002/001607 WO2002088100A2 (fr) | 2001-05-02 | 2002-04-29 | 3-piperidinopropiophenones dopees et produits pharmaceutiques contenant ces composes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20034863D0 NO20034863D0 (no) | 2003-10-31 |
| NO20034863L true NO20034863L (no) | 2003-12-30 |
Family
ID=7684543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20034863A NO20034863L (no) | 2001-05-02 | 2003-10-31 | Deutererte 3-piperidinopropiofenon så vel som legemidler som inneholder disse forbindelser |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7307091B2 (fr) |
| EP (1) | EP1383752B1 (fr) |
| JP (1) | JP4373097B2 (fr) |
| KR (1) | KR100894846B1 (fr) |
| CN (2) | CN1293064C (fr) |
| AT (1) | ATE298324T1 (fr) |
| AU (1) | AU2002257562B2 (fr) |
| CA (1) | CA2446890C (fr) |
| CZ (1) | CZ20033060A3 (fr) |
| DE (2) | DE10123129A1 (fr) |
| DK (1) | DK1383752T3 (fr) |
| ES (1) | ES2244768T3 (fr) |
| HU (1) | HUP0400077A2 (fr) |
| IL (1) | IL158668A0 (fr) |
| IS (1) | IS7006A (fr) |
| NO (1) | NO20034863L (fr) |
| NZ (1) | NZ529586A (fr) |
| PL (1) | PL363313A1 (fr) |
| PT (1) | PT1383752E (fr) |
| RU (1) | RU2296755C2 (fr) |
| SI (1) | SI1383752T1 (fr) |
| WO (1) | WO2002088100A2 (fr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10261807A1 (de) * | 2002-12-19 | 2004-07-01 | Turicum Drug Development Ag | Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel |
| HUP0300929A3 (en) * | 2003-04-09 | 2005-06-28 | Richter Gedeon Vegyeszet | Analgetic and/or muscle relaxant pharmaceutical composition |
| DE102005014080B4 (de) * | 2005-03-21 | 2007-11-22 | Birds Pharma Gmbh Berolina Innovative Research & Development Services | Additionssalze des Tolperison, Verfahren zu deren Herstellung, Verwendung derselben und diese enthaltende Arzneimittel |
| JP5448448B2 (ja) * | 2005-07-26 | 2014-03-19 | タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 同位体置換されたプロトンポンプインヒビター |
| US7601737B2 (en) * | 2005-07-26 | 2009-10-13 | Nycomed Gmbh | Isotopically substituted proton pump inhibitors |
| TWI410409B (zh) * | 2005-07-26 | 2013-10-01 | Takeda Gmbh | 同位素取代之潘托拉唑（ｐａｎｔｏｐｒａｚｏｌｅ） |
| AU2006299424A1 (en) * | 2005-10-06 | 2007-04-12 | Auspex Pharmaceuticals, Inc. | Deuterated inhibitors of gastric H+, K+-ATPase with enhanced therapeutic properties |
| CA2651732C (fr) | 2006-05-18 | 2014-10-14 | Mannkind Corporation | Inhibiteurs de kinases intracellulaires |
| US20080039473A1 (en) * | 2006-08-08 | 2008-02-14 | Auspex Pharmaceuticals, Inc. | Preparation and utility of substituted quinazoline compounds with alpha-adrenergic blocking effects |
| EA201390332A1 (ru) * | 2010-09-03 | 2013-08-30 | Ивакс Интернэшнл Гмбх | Дейтерированные аналоги придопидина, применимые в качестве допаминергических стабилизаторов |
| KR102495941B1 (ko) | 2013-12-03 | 2023-02-06 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 신규한 방법 |
| BR112016023162B1 (pt) | 2014-04-04 | 2022-11-29 | Intra-Cellular Therapies, Inc | Compostos orgânicos gama-carbolinas, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento ou na profilaxia de transtornos de sistema nervoso central |
| WO2017105881A1 (fr) * | 2015-12-15 | 2017-06-22 | NeuForm Pharmaceuticals, Inc. | Composés deutérés pour traiter la douleur |
| EP3888656A1 (fr) | 2016-03-25 | 2021-10-06 | Intra-Cellular Therapies, Inc. | Composés gamma-carbolines deutérés hétérocycliques et leur utilisation pour le traitement ou la prévention d'un désordre du système nerveux central |
| US11331316B2 (en) | 2016-10-12 | 2022-05-17 | Intra-Cellular Therapies, Inc. | Amorphous solid dispersions |
| CN106588817A (zh) * | 2016-12-13 | 2017-04-26 | 湖南亚大制药有限公司 | 一种盐酸乙哌立松的合成方法 |
| CA3054841A1 (fr) | 2017-03-24 | 2018-09-27 | Intra-Cellular Therapies, Inc. | Nouvelles compositions et methodes |
| EP3843738A4 (fr) | 2018-08-31 | 2022-06-01 | Intra-Cellular Therapies, Inc. | Nouvelles méthodes |
| WO2020047408A1 (fr) | 2018-08-31 | 2020-03-05 | Intra-Cellular Therapies, Inc. | Nouvelles méthodes |
| CN110845443B (zh) * | 2019-12-11 | 2023-09-05 | 嘉实（湖南）医药科技有限公司 | 一种制备高纯度盐酸托哌酮的方法 |
| JP7506039B2 (ja) | 2020-03-25 | 2024-06-25 | カシオ計算機株式会社 | 売上データ処理装置、レシート発行方法及びプログラム |
| CN117003605B (zh) * | 2023-08-07 | 2024-06-11 | 宁波萃英化学技术有限公司 | 一种氘代萘基蒽类化合物的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3995047A (en) * | 1973-12-14 | 1976-11-30 | Eisai Co., Ltd. | Propiophenone derivatives in the treatment of pathological muscular conditions |
| JPS5527914B2 (fr) * | 1973-12-14 | 1980-07-24 | ||
| HU33131A (fr) * | 1984-01-26 | 1984-10-29 |
-
2001
- 2001-05-02 DE DE10123129A patent/DE10123129A1/de not_active Withdrawn
-
2002
- 2002-04-29 JP JP2002585402A patent/JP4373097B2/ja not_active Expired - Fee Related
- 2002-04-29 EP EP02727303A patent/EP1383752B1/fr not_active Expired - Lifetime
- 2002-04-29 CN CNB028106121A patent/CN1293064C/zh not_active Expired - Fee Related
- 2002-04-29 CZ CZ20033060A patent/CZ20033060A3/cs unknown
- 2002-04-29 CN CNA2006101485698A patent/CN101002770A/zh active Pending
- 2002-04-29 ES ES02727303T patent/ES2244768T3/es not_active Expired - Lifetime
- 2002-04-29 AT AT02727303T patent/ATE298324T1/de not_active IP Right Cessation
- 2002-04-29 US US10/476,743 patent/US7307091B2/en not_active Expired - Lifetime
- 2002-04-29 DE DE50203456T patent/DE50203456D1/de not_active Expired - Lifetime
- 2002-04-29 DK DK02727303T patent/DK1383752T3/da active
- 2002-04-29 IL IL15866802A patent/IL158668A0/xx unknown
- 2002-04-29 RU RU2003133924/04A patent/RU2296755C2/ru not_active IP Right Cessation
- 2002-04-29 PT PT02727303T patent/PT1383752E/pt unknown
- 2002-04-29 SI SI200230177T patent/SI1383752T1/sl unknown
- 2002-04-29 PL PL02363313A patent/PL363313A1/xx unknown
- 2002-04-29 KR KR1020037014301A patent/KR100894846B1/ko not_active IP Right Cessation
- 2002-04-29 CA CA2446890A patent/CA2446890C/fr not_active Expired - Fee Related
- 2002-04-29 WO PCT/DE2002/001607 patent/WO2002088100A2/fr active IP Right Grant
- 2002-04-29 NZ NZ529586A patent/NZ529586A/en unknown
- 2002-04-29 AU AU2002257562A patent/AU2002257562B2/en not_active Ceased
- 2002-04-29 HU HU0400077A patent/HUP0400077A2/hu unknown
-
2003
- 2003-10-30 IS IS7006A patent/IS7006A/is unknown
- 2003-10-31 NO NO20034863A patent/NO20034863L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20040015240A (ko) | 2004-02-18 |
| DK1383752T3 (da) | 2005-10-17 |
| CA2446890A1 (fr) | 2002-11-07 |
| PT1383752E (pt) | 2005-11-30 |
| WO2002088100A2 (fr) | 2002-11-07 |
| AU2002257562B2 (en) | 2007-01-11 |
| US20040186136A1 (en) | 2004-09-23 |
| SI1383752T1 (sl) | 2005-12-31 |
| KR100894846B1 (ko) | 2009-04-24 |
| DE50203456D1 (de) | 2005-07-28 |
| IS7006A (is) | 2003-10-30 |
| RU2296755C2 (ru) | 2007-04-10 |
| ES2244768T3 (es) | 2005-12-16 |
| RU2003133924A (ru) | 2005-05-10 |
| NO20034863D0 (no) | 2003-10-31 |
| EP1383752B1 (fr) | 2005-06-22 |
| CZ20033060A3 (cs) | 2004-09-15 |
| CN1293064C (zh) | 2007-01-03 |
| CA2446890C (fr) | 2010-02-23 |
| US7307091B2 (en) | 2007-12-11 |
| NZ529586A (en) | 2005-07-29 |
| ATE298324T1 (de) | 2005-07-15 |
| PL363313A1 (en) | 2004-11-15 |
| HUP0400077A2 (hu) | 2004-04-28 |
| DE10123129A1 (de) | 2002-11-14 |
| CN101002770A (zh) | 2007-07-25 |
| EP1383752A2 (fr) | 2004-01-28 |
| WO2002088100A3 (fr) | 2003-05-30 |
| CN1527823A (zh) | 2004-09-08 |
| JP4373097B2 (ja) | 2009-11-25 |
| JP2004527558A (ja) | 2004-09-09 |
| IL158668A0 (en) | 2004-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |