NO20032270L - Imidazol- og benzimidazolcaspaseinhibitorer og anvendelse derav - Google Patents

Imidazol- og benzimidazolcaspaseinhibitorer og anvendelse derav

Info

Publication number
NO20032270L
NO20032270L NO20032270A NO20032270A NO20032270L NO 20032270 L NO20032270 L NO 20032270L NO 20032270 A NO20032270 A NO 20032270A NO 20032270 A NO20032270 A NO 20032270A NO 20032270 L NO20032270 L NO 20032270L
Authority
NO
Norway
Prior art keywords
benzimidazole
imidazole
caspase inhibitors
caspase
inhibitors
Prior art date
Application number
NO20032270A
Other languages
English (en)
Norwegian (no)
Other versions
NO20032270D0 (no
Inventor
David Kay
Julian M C Golec
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20032270D0 publication Critical patent/NO20032270D0/no
Publication of NO20032270L publication Critical patent/NO20032270L/no

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    • C—CHEMISTRY; METALLURGY
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    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
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    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
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    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
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    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
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    • C07K5/06—Dipeptides
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  • Medicinal Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
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NO20032270A 2000-11-21 2003-05-20 Imidazol- og benzimidazolcaspaseinhibitorer og anvendelse derav NO20032270L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25225200P 2000-11-21 2000-11-21
PCT/US2001/047688 WO2002042278A2 (en) 2000-11-21 2001-11-19 Imidazole and benzimidazole caspase inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
NO20032270D0 NO20032270D0 (no) 2003-05-20
NO20032270L true NO20032270L (no) 2003-07-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
NO20032270A NO20032270L (no) 2000-11-21 2003-05-20 Imidazol- og benzimidazolcaspaseinhibitorer og anvendelse derav

Country Status (28)

Country Link
US (1) US7205327B2 (de)
EP (1) EP1341767B1 (de)
JP (2) JP4349802B2 (de)
KR (1) KR20040020042A (de)
CN (1) CN1298707C (de)
AP (1) AP2003002811A0 (de)
AT (1) ATE359274T1 (de)
AU (1) AU2002232541A1 (de)
BG (1) BG107841A (de)
BR (1) BR0115546A (de)
CA (1) CA2429630A1 (de)
CO (1) CO7250442A2 (de)
CZ (1) CZ20031730A3 (de)
DE (1) DE60127860T2 (de)
EA (1) EA200300601A1 (de)
ES (1) ES2283456T3 (de)
HK (1) HK1058672A1 (de)
HR (1) HRP20030494A2 (de)
HU (1) HUP0301870A3 (de)
IL (1) IL155937A0 (de)
IS (1) IS6822A (de)
MX (1) MXPA03004459A (de)
NO (1) NO20032270L (de)
NZ (1) NZ526420A (de)
PL (1) PL362612A1 (de)
SK (1) SK7792003A3 (de)
WO (1) WO2002042278A2 (de)
ZA (1) ZA200303895B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
AU2003211052A1 (en) * 2002-02-11 2003-09-04 Vertex Pharmaceuticals Incorporated Phospholipids as caspase inhibitor prodrugs
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