IS6822A - Imidazól- og bezimidazól kaspasatálmar og notkun þeirra - Google Patents

Imidazól- og bezimidazól kaspasatálmar og notkun þeirra

Info

Publication number
IS6822A
IS6822A IS6822A IS6822A IS6822A IS 6822 A IS6822 A IS 6822A IS 6822 A IS6822 A IS 6822A IS 6822 A IS6822 A IS 6822A IS 6822 A IS6822 A IS 6822A
Authority
IS
Iceland
Prior art keywords
bezimidazole
imidazole
caspase inhibitors
caspase
inhibitors
Prior art date
Application number
IS6822A
Other languages
English (en)
Inventor
Kay David
Golec Julian
Original Assignee
Vertex Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharmaceuticals Incorporated filed Critical Vertex Pharmaceuticals Incorporated
Publication of IS6822A publication Critical patent/IS6822A/is

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    • C—CHEMISTRY; METALLURGY
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    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
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    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
IS6822A 2000-11-21 2003-05-20 Imidazól- og bezimidazól kaspasatálmar og notkun þeirra IS6822A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25225200P 2000-11-21 2000-11-21
PCT/US2001/047688 WO2002042278A2 (en) 2000-11-21 2001-11-19 Imidazole and benzimidazole caspase inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
IS6822A true IS6822A (is) 2003-05-20

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ID=22955229

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6822A IS6822A (is) 2000-11-21 2003-05-20 Imidazól- og bezimidazól kaspasatálmar og notkun þeirra

Country Status (28)

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US (1) US7205327B2 (is)
EP (1) EP1341767B1 (is)
JP (2) JP4349802B2 (is)
KR (1) KR20040020042A (is)
CN (1) CN1298707C (is)
AP (1) AP2003002811A0 (is)
AT (1) ATE359274T1 (is)
AU (1) AU2002232541A1 (is)
BG (1) BG107841A (is)
BR (1) BR0115546A (is)
CA (1) CA2429630A1 (is)
CO (1) CO7250442A2 (is)
CZ (1) CZ20031730A3 (is)
DE (1) DE60127860T2 (is)
EA (1) EA200300601A1 (is)
ES (1) ES2283456T3 (is)
HK (1) HK1058672A1 (is)
HR (1) HRP20030494A2 (is)
HU (1) HUP0301870A3 (is)
IL (1) IL155937A0 (is)
IS (1) IS6822A (is)
MX (1) MXPA03004459A (is)
NO (1) NO20032270L (is)
NZ (1) NZ526420A (is)
PL (1) PL362612A1 (is)
SK (1) SK7792003A3 (is)
WO (1) WO2002042278A2 (is)
ZA (1) ZA200303895B (is)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
WO2003068242A1 (en) * 2002-02-11 2003-08-21 Vertex Pharmaceuticals Incorporated Phospholipids as caspase inhibitor prodrugs
EP1499898A2 (en) * 2002-04-19 2005-01-26 Vertex Pharmaceuticals Incorporated Regulation of tnf-alpha
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