NO20021931L - L-pantolacton-hydrolase og en fremgangsmåte for fremstilling av D-pantolacton - Google Patents

L-pantolacton-hydrolase og en fremgangsmåte for fremstilling av D-pantolacton

Info

Publication number
NO20021931L
NO20021931L NO20021931A NO20021931A NO20021931L NO 20021931 L NO20021931 L NO 20021931L NO 20021931 A NO20021931 A NO 20021931A NO 20021931 A NO20021931 A NO 20021931A NO 20021931 L NO20021931 L NO 20021931L
Authority
NO
Norway
Prior art keywords
pantolactone
preparation
hydrolase
proteins
relates
Prior art date
Application number
NO20021931A
Other languages
English (en)
Norwegian (no)
Other versions
NO20021931D0 (no
Inventor
Maria Kesseler
Bernhard Hauer
Thomas Friedrich
Ralf Mattes
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19952501A external-priority patent/DE19952501A1/de
Priority claimed from DE10029194A external-priority patent/DE10029194A1/de
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO20021931L publication Critical patent/NO20021931L/no
Publication of NO20021931D0 publication Critical patent/NO20021931D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
NO20021931A 1999-10-29 2002-04-24 L-pantolacton-hydrolase og en fremgangsmåte for fremstilling av D-pantolacton NO20021931D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19952501A DE19952501A1 (de) 1999-10-29 1999-10-29 L-Pantolacton-Hydrolase und ein Verfahren zur Herstellung von D-Pantolacton
DE10029194A DE10029194A1 (de) 2000-06-19 2000-06-19 L-Pantolacton-Hydrolase und ein Verfahren zur Herstellung von D-Pantolacton
PCT/EP2000/010320 WO2001032890A1 (fr) 1999-10-29 2000-10-20 Hydrolase de l-pantolactone et procede de production de d-pantolactone

Publications (2)

Publication Number Publication Date
NO20021931L true NO20021931L (no) 2002-04-24
NO20021931D0 NO20021931D0 (no) 2002-04-24

Family

ID=26006072

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20021931A NO20021931D0 (no) 1999-10-29 2002-04-24 L-pantolacton-hydrolase og en fremgangsmåte for fremstilling av D-pantolacton

Country Status (17)

Country Link
US (1) US6998258B1 (fr)
EP (1) EP1224296A1 (fr)
JP (1) JP2003530080A (fr)
KR (1) KR20020043254A (fr)
CN (1) CN1384880A (fr)
AU (1) AU782517B2 (fr)
BR (1) BR0015114A (fr)
CA (1) CA2389064A1 (fr)
CZ (1) CZ20021449A3 (fr)
EE (1) EE200200225A (fr)
HU (1) HUP0203704A3 (fr)
IL (1) IL148973A0 (fr)
MX (1) MXPA02003417A (fr)
NO (1) NO20021931D0 (fr)
PL (1) PL355487A1 (fr)
RU (1) RU2002114044A (fr)
WO (1) WO2001032890A1 (fr)

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US20030194798A1 (en) * 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
DE50307835D1 (de) 2002-12-02 2007-09-13 Basf Ag L-rhamnose-induzierbare expressionssysteme
CN1768141B (zh) * 2003-03-28 2012-10-10 帝斯曼知识产权资产管理有限公司 泛酸内酯水解酶
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US8718231B2 (en) 2008-05-22 2014-05-06 Vladimir Balakin X-ray tomography method and apparatus used in conjunction with a charged particle cancer therapy system
US9177751B2 (en) 2008-05-22 2015-11-03 Vladimir Balakin Carbon ion beam injector apparatus and method of use thereof
US10092776B2 (en) 2008-05-22 2018-10-09 Susan L. Michaud Integrated translation/rotation charged particle imaging/treatment apparatus and method of use thereof
US8309941B2 (en) * 2008-05-22 2012-11-13 Vladimir Balakin Charged particle cancer therapy and patient breath monitoring method and apparatus
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US8598543B2 (en) * 2008-05-22 2013-12-03 Vladimir Balakin Multi-axis/multi-field charged particle cancer therapy method and apparatus
US9782140B2 (en) 2008-05-22 2017-10-10 Susan L. Michaud Hybrid charged particle / X-ray-imaging / treatment apparatus and method of use thereof
US8975600B2 (en) 2008-05-22 2015-03-10 Vladimir Balakin Treatment delivery control system and method of operation thereof
US9981147B2 (en) 2008-05-22 2018-05-29 W. Davis Lee Ion beam extraction apparatus and method of use thereof
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US8373143B2 (en) * 2008-05-22 2013-02-12 Vladimir Balakin Patient immobilization and repositioning method and apparatus used in conjunction with charged particle cancer therapy
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US9910166B2 (en) 2008-05-22 2018-03-06 Stephen L. Spotts Redundant charged particle state determination apparatus and method of use thereof
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US8907309B2 (en) 2009-04-17 2014-12-09 Stephen L. Spotts Treatment delivery control system and method of operation thereof
US8178859B2 (en) * 2008-05-22 2012-05-15 Vladimir Balakin Proton beam positioning verification method and apparatus used in conjunction with a charged particle cancer therapy system
US8642978B2 (en) 2008-05-22 2014-02-04 Vladimir Balakin Charged particle cancer therapy dose distribution method and apparatus
US9855444B2 (en) 2008-05-22 2018-01-02 Scott Penfold X-ray detector for proton transit detection apparatus and method of use thereof
US9744380B2 (en) 2008-05-22 2017-08-29 Susan L. Michaud Patient specific beam control assembly of a cancer therapy apparatus and method of use thereof
US9498649B2 (en) 2008-05-22 2016-11-22 Vladimir Balakin Charged particle cancer therapy patient constraint apparatus and method of use thereof
US10070831B2 (en) 2008-05-22 2018-09-11 James P. Bennett Integrated cancer therapy—imaging apparatus and method of use thereof
US10029122B2 (en) 2008-05-22 2018-07-24 Susan L. Michaud Charged particle—patient motion control system apparatus and method of use thereof
US9682254B2 (en) 2008-05-22 2017-06-20 Vladimir Balakin Cancer surface searing apparatus and method of use thereof
US8627822B2 (en) * 2008-07-14 2014-01-14 Vladimir Balakin Semi-vertical positioning method and apparatus used in conjunction with a charged particle cancer therapy system
US8625739B2 (en) 2008-07-14 2014-01-07 Vladimir Balakin Charged particle cancer therapy x-ray method and apparatus
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EP3310768B1 (fr) 2015-06-19 2020-04-15 Basf Se Préparation de la pantolactone
US9907981B2 (en) 2016-03-07 2018-03-06 Susan L. Michaud Charged particle translation slide control apparatus and method of use thereof
US10037863B2 (en) 2016-05-27 2018-07-31 Mark R. Amato Continuous ion beam kinetic energy dissipater apparatus and method of use thereof
CN113195727A (zh) 2018-10-18 2021-07-30 巴斯夫欧洲公司 用于产生丙烯酸或其盐的方法
EP3748009A1 (fr) * 2019-06-07 2020-12-09 DSM IP Assets B.V. Synthèse de l'acétate de (r)-pantolactone
CN110452861B (zh) * 2019-07-10 2021-02-09 杭州师范大学 一种基因重组工程菌及其在催化合成d-泛酰内酯中的应用

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
JPS5572182A (en) * 1978-11-28 1980-05-30 Sagami Chem Res Center Optical resolution of pantolactone
JPH0667320B2 (ja) * 1986-06-13 1994-08-31 三菱化成株式会社 Ｄ−パントラクトンの製造法
JPH0655156B2 (ja) * 1986-06-13 1994-07-27 三菱化成株式会社 Ｄｌ−パントラクトンの光学分割法
JP2844354B2 (ja) 1989-08-03 1999-01-06 富士薬品工業株式会社 Ｄ―パントラクトンの製造法
DE4005150A1 (de) 1990-02-17 1991-08-22 Hoechst Ag Verfahren zur enzymatischen racematspaltung von pantolacton
JP3011449B2 (ja) 1990-10-05 2000-02-21 富士薬品工業株式会社 Ｄ―パントラクトン加水分解酵素およびその製造法
CA2064676A1 (fr) 1991-04-02 1992-10-03 Manfred Schneider Biocatalyseur immobilise, sa preparation et on utilisation pour realiser une synthese d'ester dans un reacteur a colonne
DE4126580A1 (de) 1991-08-12 1993-02-18 Degussa D-2,4-dihydroxy-3,3-dimethylbutansaeurenitril, seine herstellung und verwendung
KR100266037B1 (ko) 1992-10-15 2000-09-15 에모토 간지 금속대의 연속침탄방법
AU1810197A (en) * 1995-09-13 1997-04-01 Fuji Yakuhin Kogyo Kabushiki Kaisha D-pantolactone hydrolase and gene encoding the same
US6395529B1 (en) * 1998-11-10 2002-05-28 Novozymes Biotech, Inc. Polypeptides having lactonohydrolase activity and nucleic acids encoding same
WO2000028043A2 (fr) * 1998-11-10 2000-05-18 Novozymes Biotech, Inc. Polypeptides presentant une activite lactonohydrolase et acides nucleiques codant ces polypeptides

Also Published As

Publication number Publication date
HUP0203704A3 (en) 2006-03-28
PL355487A1 (en) 2004-05-04
CN1384880A (zh) 2002-12-11
BR0015114A (pt) 2002-07-16
HUP0203704A2 (hu) 2003-03-28
RU2002114044A (ru) 2004-03-27
AU1141601A (en) 2001-05-14
CZ20021449A3 (cs) 2002-10-16
EP1224296A1 (fr) 2002-07-24
US6998258B1 (en) 2006-02-14
NO20021931D0 (no) 2002-04-24
EE200200225A (et) 2003-06-16
JP2003530080A (ja) 2003-10-14
MXPA02003417A (es) 2002-08-20
IL148973A0 (en) 2002-11-10
WO2001032890A1 (fr) 2001-05-10
CA2389064A1 (fr) 2001-05-10
AU782517B2 (en) 2005-08-04
KR20020043254A (ko) 2002-06-08

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