NO20013698L - Fremgangsmåte for identifisering av N-terminalt proBNP - Google Patents

Fremgangsmåte for identifisering av N-terminalt proBNP

Info

Publication number
NO20013698L
NO20013698L NO20013698A NO20013698A NO20013698L NO 20013698 L NO20013698 L NO 20013698L NO 20013698 A NO20013698 A NO 20013698A NO 20013698 A NO20013698 A NO 20013698A NO 20013698 L NO20013698 L NO 20013698L
Authority
NO
Norway
Prior art keywords
bnp
terminal pro
identifying
terminal probnp
recombinant
Prior art date
Application number
NO20013698A
Other languages
English (en)
Other versions
NO329866B1 (no
NO20013698D0 (no
Inventor
Johann Karl
Helmut Lill
Peter Stahl
Kerstin Krueger
Anneliese Borgya
Andreas Gallusser
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of NO20013698D0 publication Critical patent/NO20013698D0/no
Publication of NO20013698L publication Critical patent/NO20013698L/no
Publication of NO329866B1 publication Critical patent/NO329866B1/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of Radiation (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
NO20013698A 1999-01-29 2001-07-27 Fremgangsmate for pavisning av nativt N-terminalt proBNP i en prove som utfores i "sandwich"-format ved anvendelse av minst to antistoffer som gjenkjenner forskjellige epitoper i det native N-terminale proBNP, og som samtidig kan bindes til nativt N-terminalt proBNP, anvendelse av fremgangsmaten for differensiering mellom prover, anvendelse av rekombinant N-terminalt proBNP som standard i en fremgangsmate, antistoffer mot N-terminalt proBNP fremstilt ved immunisering av en egnet organisme med rekombinant fremstilt N-terminalt proBNP, samt cellelinje. NO329866B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19903489 1999-01-29
DE19911044 1999-03-12
PCT/EP2000/000602 WO2000045176A2 (de) 1999-01-29 2000-01-27 VERFAHREN ZUM NACHWEIS VON N-TERMINALEM proBNP

Publications (3)

Publication Number Publication Date
NO20013698D0 NO20013698D0 (no) 2001-07-27
NO20013698L true NO20013698L (no) 2001-09-28
NO329866B1 NO329866B1 (no) 2011-01-17

Family

ID=26051550

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013698A NO329866B1 (no) 1999-01-29 2001-07-27 Fremgangsmate for pavisning av nativt N-terminalt proBNP i en prove som utfores i "sandwich"-format ved anvendelse av minst to antistoffer som gjenkjenner forskjellige epitoper i det native N-terminale proBNP, og som samtidig kan bindes til nativt N-terminalt proBNP, anvendelse av fremgangsmaten for differensiering mellom prover, anvendelse av rekombinant N-terminalt proBNP som standard i en fremgangsmate, antistoffer mot N-terminalt proBNP fremstilt ved immunisering av en egnet organisme med rekombinant fremstilt N-terminalt proBNP, samt cellelinje.

Country Status (21)

Country Link
US (1) US20070059767A1 (no)
EP (2) EP1151304B9 (no)
JP (1) JP3987284B2 (no)
KR (1) KR100572542B1 (no)
CN (2) CN101046478B (no)
AT (2) ATE373826T1 (no)
AU (1) AU758562B2 (no)
CA (1) CA2359667C (no)
CY (1) CY1108450T1 (no)
DE (2) DE50014666D1 (no)
DK (2) DK1151304T3 (no)
ES (2) ES2312062T3 (no)
HU (1) HU228625B1 (no)
IL (2) IL144062A0 (no)
NO (1) NO329866B1 (no)
NZ (1) NZ512762A (no)
PL (1) PL204235B1 (no)
PT (1) PT1698901E (no)
RU (1) RU2218568C2 (no)
WO (1) WO2000045176A2 (no)
ZA (1) ZA200106193B (no)

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MXPA03004105A (es) 2002-05-14 2004-10-15 Hoffmann La Roche Elaboracion de una prognosis en casos de enfermedad cardiaca usando una combinacion de marcadores.
GB0216191D0 (en) * 2002-07-11 2002-08-21 Univ Leicester Plasma urotensin in human heart failure
FR2843396B1 (fr) 2002-08-07 2005-04-15 Bio Rad Pasteur Anticorps specifiques pour le diagnostic de l'insuffisance cardiaque
US6960472B2 (en) * 2002-11-18 2005-11-01 Ottawa Heart Institute Research Corporation Monoclonal antibodies against N-Terminus proBNP
US20050287613A1 (en) * 2002-11-18 2005-12-29 George Jackowski Polyclonal-polyclonal ELISA assay for detecting N-terminus-proBNP
US20040096919A1 (en) 2002-11-18 2004-05-20 Michelle Davey Polyclonal-monoclonal ELISA assay for detecting N-terminus proBNP
EP1562990B1 (en) 2002-11-18 2010-07-21 Syn X Pharma, Inc. Polyclonal-monoclonal elisa assay for detecting n-terminus probnp
ES2271674T3 (es) * 2002-11-20 2007-04-16 B.R.A.H.M.S Aktiengesellschaft Inmunoensayo tipo sandwich para la determinacion de peptidos parciales proanp.
US7767419B2 (en) * 2003-02-04 2010-08-03 Nexus Dx, Inc. Calibrator for NT-proBNP immunoassay
ES2372282T3 (es) * 2003-05-12 2012-01-18 F. Hoffmann-La Roche Ag Método para detectar probnp con un anticuerpo monoclonal que fija los aminoácidos 38-43.
GB2403533A (en) 2003-06-30 2005-01-05 Orion Corp Atrial natriuretic peptide and brain natriuretic peptide and assays and uses thereof
EP1522857A1 (en) * 2003-10-09 2005-04-13 Universiteit Maastricht Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2
DE10355731A1 (de) * 2003-11-28 2005-06-30 Roche Diagnostics Gmbh Analytischer Sandwichtest zur Bestimmung von NT-proBNP
GB0329288D0 (en) 2003-12-18 2004-01-21 Inverness Medical Switzerland Monitoring method and apparatus
AT500800B1 (de) * 2004-09-08 2008-07-15 Biomedica Medizinprodukte Gmbh Verfahren zur bestimmung von probnp
FR2863269B1 (fr) * 2005-01-14 2006-05-26 Bio Rad Pasteur Peptides specifiques pour le diagnostic de l'insuffisance cardiaque
DE102005003687A1 (de) * 2005-01-26 2006-07-27 Sphingo Tec Gmbh Immunoassay zur Bestimmung der Freisetzung von Neurotensin in die Zirkulation
EP1722232A1 (en) * 2005-05-09 2006-11-15 F.Hoffmann-La Roche Ag Devices and methods for diagnosing or predicting early stage cardiac dysfunctions
EP1909206A1 (de) * 2006-09-11 2008-04-09 Roche Diagnostics GmbH Messbereichserweiterung chromatografischer Schnellteste
EP1909207B1 (de) * 2006-09-11 2015-03-04 F.Hoffmann-La Roche Ag Messbereichserweiterung chromatografischer Schnellteste
DE102006060835A1 (de) * 2006-12-22 2008-06-26 Brahms Aktiengesellschaft Diagnose und Risikostratifizierung des akuten Koronarsyndroms mittels CT-proET-1 in Kombination mit NT-proBNP
DK2115477T3 (en) * 2007-01-25 2015-08-10 Hoffmann La Roche USE OF IGFBP-7 IN THE EVIDENCE OF HEART FAILURE
ES2430290T3 (es) * 2007-03-06 2013-11-19 F. Hoffmann-La Roche Ag Utilización de péptidos de tipo PNC para predecir la necesidad de diálisis
JP5081930B2 (ja) 2007-03-08 2012-11-28 エフ．ホフマン−ラ ロシュ アーゲー 心不全の評価におけるｓｌｉｍ−１の使用
JP5198565B2 (ja) * 2007-08-30 2013-05-15 エフ．ホフマン−ラ ロシュ アーゲー 心疾患に関連する又は関連しないｇｄｆ−１５の上昇の区別のための手段及び方法
ES2526928T3 (es) 2008-04-30 2015-01-16 The Governing Council Of The University Of Toronto Uso de SFRP-3 en la evaluación de la insuficiencia cardíaca
WO2011012268A1 (en) 2009-07-27 2011-02-03 Roche Diagnostics Gmbh Use of mimecan in the assessment of heart failure
BR112012005331A2 (pt) * 2009-09-14 2019-09-24 Koninl Philips Electronics Nv "imunoensaio para a detecção de um analito em uma amostra, método para a detecção dos analitos em uma amostra, dispositivo biosensor e kit de partes adequadas para detectar um analito em uma amostra"
CN101819205A (zh) * 2010-06-03 2010-09-01 中国人民解放军第三军医大学 人n端b型利钠肽原免疫分析试剂盒及其制备方法
EP2601531A1 (en) * 2010-08-04 2013-06-12 IDEXX Laboratories, Inc. Detection of degradation products of canine nt-probnp
EP2715353B1 (en) 2011-05-31 2016-08-24 IDEXX Laboratories, Inc. DETECTION OF DEGRADATION PRODUCTS OF FELINE NT-proBNP
CN102692512A (zh) * 2012-06-26 2012-09-26 南京基蛋生物科技有限公司 NT-proBNP双抗夹心快速检测试剂盒
CN109678958B (zh) * 2019-01-31 2022-03-18 重庆探生科技有限公司 一种人NT-proBNP特异性重组羊单克隆抗体及其制备方法和应用
CN114207444A (zh) 2019-08-13 2022-03-18 挪威金田有限公司 用于NT-proBNP定量的高灵敏度颗粒增强测定
IL311792A (en) 2021-10-01 2024-05-01 Gentian As A new method for determining the concentration of N-terminal prohormone BNP (NT-PROBNP) in a sample

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
US4496654A (en) * 1983-04-08 1985-01-29 Quidel Detection of HCG with solid phase support having avidin coating
US4737453A (en) * 1984-12-12 1988-04-12 Immunomedics, Inc. Sandwich immunoassay utilizing a separation specific binding substance
DE3509958A1 (de) * 1985-03-20 1986-09-25 Bayer Ag, 5090 Leverkusen Monoklonale antikoerper gegen atriale, natriuretische peptide vom menschen
CA1339210C (en) * 1988-05-31 1997-08-05 John Lewicki Recombinant techniques for production of novel natriuretic and vasodilator peptides
GB9211686D0 (en) * 1992-06-03 1992-07-15 Medisinsk Innovation A S Chemical compounds
US6117644A (en) * 1998-06-04 2000-09-12 Ottawa Heart Institute Research Corporation Predicting and detecting cardiac allograft rejection
WO2008091207A1 (en) * 2007-01-26 2008-07-31 Telefonaktiebolaget Lm Ericsson (Publ) Border region processing in images

Also Published As

Publication number Publication date
EP1151304A2 (de) 2001-11-07
HU228625B1 (en) 2013-04-29
PL364798A1 (en) 2004-12-13
EP1698901A1 (de) 2006-09-06
IL144062A (en) 2007-09-20
ES2292426T3 (es) 2008-03-16
ZA200106193B (en) 2002-05-02
AU2545100A (en) 2000-08-18
ES2312062T3 (es) 2009-02-16
ATE373826T1 (de) 2007-10-15
KR100572542B1 (ko) 2006-04-24
CN101046478A (zh) 2007-10-03
CN101046478B (zh) 2013-04-03
HUP0105195A2 (hu) 2002-04-29
CA2359667C (en) 2009-10-20
DE50014666D1 (de) 2007-10-31
WO2000045176A3 (de) 2001-07-26
EP1698901B1 (de) 2008-07-30
AU758562B2 (en) 2003-03-27
JP3987284B2 (ja) 2007-10-03
RU2218568C2 (ru) 2003-12-10
ATE403158T1 (de) 2008-08-15
CN1339107A (zh) 2002-03-06
PT1698901E (pt) 2008-10-08
KR20010101874A (ko) 2001-11-15
CY1108450T1 (el) 2014-04-09
CN1327228C (zh) 2007-07-18
DK1151304T3 (da) 2008-01-28
NO329866B1 (no) 2011-01-17
US20070059767A1 (en) 2007-03-15
IL144062A0 (en) 2002-04-21
DK1698901T3 (da) 2008-12-08
EP1151304B1 (de) 2007-09-19
DE50015291D1 (de) 2008-09-11
WO2000045176A2 (de) 2000-08-03
NZ512762A (en) 2003-02-28
EP1151304B9 (de) 2008-06-04
PL204235B1 (pl) 2009-12-31
CA2359667A1 (en) 2000-08-03
NO20013698D0 (no) 2001-07-27
JP2003508724A (ja) 2003-03-04
HUP0105195A3 (en) 2005-11-28

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