KR890012669A - 심방 나트륨이뇨성 폴리펩티드를 인지하는 단일클론성 항체 - Google Patents

심방 나트륨이뇨성 폴리펩티드를 인지하는 단일클론성 항체 Download PDF

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Publication number
KR890012669A
KR890012669A KR1019890002521A KR890002521A KR890012669A KR 890012669 A KR890012669 A KR 890012669A KR 1019890002521 A KR1019890002521 A KR 1019890002521A KR 890002521 A KR890002521 A KR 890002521A KR 890012669 A KR890012669 A KR 890012669A
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South Korea
Prior art keywords
anp
monoclonal antibody
monoclonal antibodies
atrial natriuretic
antibodies recognizing
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KR1019890002521A
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English (en)
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KR960008672B1 (ko
Inventor
히로오 이무라
가즈와 나까오
Original Assignee
요시또시 가즈오
시오노기세이야꾸 가부시끼가이샤
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Application filed by 요시또시 가즈오, 시오노기세이야꾸 가부시끼가이샤 filed Critical 요시또시 가즈오
Publication of KR890012669A publication Critical patent/KR890012669A/ko
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Publication of KR960008672B1 publication Critical patent/KR960008672B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

내용 없음.

Description

심방 나트륨이뇨성 폴리펩티드를 인지하는 단일클론성 항체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는[125Ⅰ]α-hANP와 단일 클론성 항체 KY-ANP-Ⅱ사이의 결합의 스캐챠드 도면을 나타낸다.
제2도는 KY-ANP-Ⅱ를 이용한 RIA에서의 α-hANP표준 곡선 및 관련 팹티드의 교차 반응 곡선을 나타낸다.

Claims (9)

  1. α-ANP의 N-말단을 인지하는 단일클론성 항체.
  2. 제1항에 있어서, α-ANP의 N-말단상의 2내지 3 아미노산 잔기를 인지하는 단일클론성 항체.
  3. 제2항에 있어서, α-ANP의 고리구조도 인지하는 단일클론성 항체.
  4. 제3항에 있어서, 단일클론성 항체 KY-ANP-Ⅱ인 단일클론성 항체.
  5. 제1항의 단일클론성 항체를 생산하는 하이드리도마.
  6. 제5항에 있어서, 생쥐 하이브리도마 KY-ANP-Ⅱ인 하이브리도마.
  7. 제1항의 단일클론성 항체를 사용함을 특징으로 하는 α-ANP의 면역분석 방법.
  8. 제7항에 있어서, 분석이 경쟁법에 의해 행해지는 면역 분석 방법.
  9. 제8항에 있어서, 분석법이 방사선 면역 분석법인 면역 분석 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890002521A 1988-02-29 1989-02-28 심방 나트륨이뇨성 폴리펩티드를 인지하는 단일클론성 항체 KR960008672B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP47280/88 1988-02-29
JP63047280A JP2724315B2 (ja) 1988-02-29 1988-02-29 α−ＡＮＰを認識するモノクローナル抗体およびα−ＡＮＰの免疫学的測定法
JP63-47280 1988-02-29

Publications (2)

Publication Number Publication Date
KR890012669A true KR890012669A (ko) 1989-09-18
KR960008672B1 KR960008672B1 (ko) 1996-06-28

Family

ID=12770879

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890002521A KR960008672B1 (ko) 1988-02-29 1989-02-28 심방 나트륨이뇨성 폴리펩티드를 인지하는 단일클론성 항체

Country Status (8)

Country Link
US (1) US5124264A (ko)
EP (1) EP0331439B1 (ko)
JP (1) JP2724315B2 (ko)
KR (1) KR960008672B1 (ko)
AT (1) ATE99360T1 (ko)
CA (1) CA1334076C (ko)
DE (1) DE68911713T2 (ko)
ES (1) ES2061973T3 (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3167415B2 (ja) * 1992-04-30 2001-05-21 オリンパス光学工業株式会社 固相免疫検査における抗原細胞の保存方法
US5789183A (en) * 1992-08-14 1998-08-04 University Of Arkansas Serological detection and identification of rice blast
ATE180058T1 (de) * 1994-12-09 1999-05-15 Shionogi & Co Sandwich-immunotestverfahren für n-peptide
US8679760B2 (en) * 2011-05-03 2014-03-25 National Cheng Kung University Biomarker and method for evaluating risk of proliferation, invasion, or metastasis of cancer
JP2016079146A (ja) * 2014-10-21 2016-05-16 東ソー株式会社 β−ＡＮＰに対する特異的測定方法
JP6508996B2 (ja) * 2015-03-24 2019-05-08 東ソー株式会社 β−ＡＮＰによる心不全の検出方法
US11110725B2 (en) 2018-08-31 2021-09-07 Hewlett-Packard Development Company, L.P. Power allocation in printing devices

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3509958A1 (de) * 1985-03-20 1986-09-25 Bayer Ag, 5090 Leverkusen Monoklonale antikoerper gegen atriale, natriuretische peptide vom menschen
CA1335082C (en) * 1987-09-01 1995-04-04 Hiroo Imura Monoclonal antibody recognizing –-hanp and a reagent for immunoassay of –-hanp

Also Published As

Publication number Publication date
JPH01221399A (ja) 1989-09-04
ES2061973T3 (es) 1994-12-16
JP2724315B2 (ja) 1998-03-09
EP0331439A3 (en) 1991-01-16
US5124264A (en) 1992-06-23
KR960008672B1 (ko) 1996-06-28
EP0331439A2 (en) 1989-09-06
DE68911713T2 (de) 1994-07-14
EP0331439B1 (en) 1993-12-29
ATE99360T1 (de) 1994-01-15
DE68911713D1 (de) 1994-02-10
CA1334076C (en) 1995-01-24

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