NO20006507L - Propenyl kefalosporinderivater - Google Patents

Propenyl kefalosporinderivater

Info

Publication number
NO20006507L
NO20006507L NO20006507A NO20006507A NO20006507L NO 20006507 L NO20006507 L NO 20006507L NO 20006507 A NO20006507 A NO 20006507A NO 20006507 A NO20006507 A NO 20006507A NO 20006507 L NO20006507 L NO 20006507L
Authority
NO
Norway
Prior art keywords
hydrogen
carbon
sulfur
nitrogen
exceeding
Prior art date
Application number
NO20006507A
Other languages
English (en)
Other versions
NO20006507D0 (no
Inventor
Peter Angehrn
Erwin Goetschi
Ingrid Heinze-Krauss
Hans G F Richter
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20006507L publication Critical patent/NO20006507L/no
Publication of NO20006507D0 publication Critical patent/NO20006507D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/40Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Fremlagt er kefalosporinderivater med den generelle forme- len R-S-CH^ CDCH hvori R er en organisk residu med en molekylvekt som ikke overstiger 400 bundet til det tilgrensende svovelatomet via karbon og består av karbon, hydrogen, og valgfritt oksygen, svovel, nitrogen og/eller halogenatomer; R1 er hydrogen, lavere alkyl eller fenyl; og A er et sekundært, tertiært eller kvaternært nitrogen atom bundet direkte til propenylgruppen og er substituert med en organisk residu med en molekylvekt som ikke overstiger 400 og består av karbon, hydrogen, og valgfritt oksygen, svovel, nitrogen og/eller halogenatomer, i tillegg til lett hydrolyserbare estere derav, farmasøytisk akseptable salter av forbindel- sene og hydrater av forbindelsene med formel I og av deres estere og salter. Også fremlagt er en prosess for deres fremstilling, mellomprodukter anvendbare deri. Medikamen- ter inneholdende sluttproduktene og anvendelse av sist- nevnte for behandling og profylakse av infeksjonssykdommer eller for fremstillingen av medikamentene.
NO20006507A 1998-06-22 2000-12-20 Propenyl kefalosporinderivater NO20006507D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98111415 1998-06-22
EP99108149 1999-04-26
PCT/EP1999/004034 WO1999067255A1 (en) 1998-06-22 1999-06-11 Propenyl cephalosporin derivatives

Publications (2)

Publication Number Publication Date
NO20006507L true NO20006507L (no) 2000-12-20
NO20006507D0 NO20006507D0 (no) 2000-12-20

Family

ID=26149364

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006507A NO20006507D0 (no) 1998-06-22 2000-12-20 Propenyl kefalosporinderivater

Country Status (16)

Country Link
US (1) US6583133B1 (no)
EP (1) EP1090013A1 (no)
JP (1) JP4033630B2 (no)
KR (1) KR100414336B1 (no)
CN (1) CN1173979C (no)
AU (1) AU761450B2 (no)
BR (1) BR9911445A (no)
CA (1) CA2335288A1 (no)
HU (1) HUP0102350A2 (no)
ID (1) ID28433A (no)
IL (1) IL140010A0 (no)
MA (1) MA26657A1 (no)
NO (1) NO20006507D0 (no)
PL (1) PL345266A1 (no)
TR (1) TR200003807T2 (no)
WO (1) WO1999067255A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020085180A (ko) * 2001-05-07 2002-11-16 주식회사 엘지생명과학 신규 세팔로스포린계 항생제 및 이의 제조 방법
KR20020085176A (ko) * 2001-05-07 2002-11-16 주식회사 엘지생명과학 신규 세팔로스포린계 항생제 및 이의 제조 방법
ITRM20020014A1 (it) * 2002-01-15 2003-07-15 Sigma Tau Ind Farmaceuti Derivati di acidi a-feniltiocarbossilici e a-fenilossicarbossilici utili per il trattamento di patologie che rispondono all'attivazione del
KR100693298B1 (ko) * 2003-06-27 2007-03-13 영진약품공업주식회사 신규한 세팔로스포린계 화합물 및 약제학적으로 허용되는염과 그의 제조 방법
JP3928086B2 (ja) * 2005-03-29 2007-06-13 塩野義製薬株式会社 3−プロペニルセフェム誘導体

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983113A (en) * 1975-08-15 1976-09-28 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US4486586A (en) 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
US4751295A (en) 1984-04-09 1988-06-14 Bristol-Myers Company Cephalosporin derivatives
CA1276929C (en) 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
FR2622585B1 (fr) 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
EP0764648B1 (en) * 1988-03-16 2002-01-16 Eisai Co., Ltd. Cephem derivatives and process for the preparation thereof
DE69231815T2 (de) 1991-03-08 2001-09-27 Biochemie Ges.M.B.H., Kundl Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
CA2143519A1 (en) * 1994-03-11 1995-09-12 Markus Bohringer Beta-lactams
CZ251896A3 (en) * 1995-09-12 1997-04-16 Hoffmann Ka Roche Ag F Cephalosporin derivatives
DK0841339T3 (da) 1996-11-06 2007-07-02 Basilea Pharmaceutica Ag Vinylpyrrolidinon-cephalosporinderivater
US6150350A (en) * 1997-09-15 2000-11-21 Hoffman-La Roche Inc. Antimicrobial compositions

Also Published As

Publication number Publication date
WO1999067255A1 (en) 1999-12-29
CN1306536A (zh) 2001-08-01
NO20006507D0 (no) 2000-12-20
JP4033630B2 (ja) 2008-01-16
PL345266A1 (en) 2001-12-03
CA2335288A1 (en) 1999-12-29
BR9911445A (pt) 2001-03-20
KR100414336B1 (ko) 2004-01-07
ID28433A (id) 2001-05-24
EP1090013A1 (en) 2001-04-11
CN1173979C (zh) 2004-11-03
JP2002518505A (ja) 2002-06-25
IL140010A0 (en) 2002-02-10
AU4608199A (en) 2000-01-10
AU761450B2 (en) 2003-06-05
TR200003807T2 (tr) 2001-06-21
HUP0102350A2 (hu) 2001-11-28
MA26657A1 (fr) 2004-12-20
US6583133B1 (en) 2003-06-24
KR20010053092A (ko) 2001-06-25

Similar Documents

Publication Publication Date Title
ATE353870T1 (de) Dibenzylaminverbindung und deren medizinische verwendung
NO20054224L (no) Nye 2-pyridinkarboksamidderivater
NO20015447D0 (no) Kinolinderivater som inhibitorer av MEK enzymer
NO20051600L (no) 1,4-disubstituerte piperidinderivater og anvendelse derav som 11-betaHSD1 inhibitorer
DK0625977T3 (da) Piperazinderivater som 5-1A-antagonister
DE3868301D1 (de) 2-(methyl(4-piperidinyl))-1,2,3,4-tetrahydro-9h-pyrido(3,4-b)indolderivate, ihre herstellung und therapeutische verwendung.
ES2048109B1 (es) Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
DK0849269T3 (da) Vinylpyrrolidincephalosporiner med basiske substituenter
HUP0401235A2 (hu) 5-HT6 receptor affinitással rendelkező arilszulfonil-származékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyászati készítmények
DE69227088D1 (de) Verwendung von 1-(aminoalkyl)-3-Quinoxalin-2-on Derivaten zur Herstellung von neuroprotektiven Mitteln
EA200101224A1 (ru) Производные пурина, способ их получения и содержащие их фармацевтические композиции
AR003137A1 (es) Una composicion farmaceutica para tratar la leucemia
NO20006507L (no) Propenyl kefalosporinderivater
EA200000389A3 (ru) Новые замещенные пиридины или пиперидины, способ их получения и содержащие их фармацевтические композиции
HUT75647A (en) Imidazolidinone derivatives and pharmaceutical compositions containing them, which are suitable for treament of senile dementia
EP1156057A4 (en) MALTO-OLIGOSACCHARID DERIVATIVES AND THEIR APPLICATIONS
ES2016017A6 (es) Procedimiento para preparar derivados de acido 1,1-dioxocefem-4-carbotiolico.
DE3674372D1 (de) 1,2,3,4,4a,9b-hexahydro-4a-aminoalkyldibenzofurane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
NZ515278A (en) Halo derivatives of 9-deoxo-9a-aza-9a- homerythromycin A their salts and preparation process
MY133207A (en) Substituted benzolactam compaunds
NO920619L (no) Oxazinobenzazolforbindelser
DK0570850T3 (da) Benzo(b)thiophen-3-yl-piperaziner, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
ATE148699T1 (de) Herstellung von 2-(2-thienyl)äthylamin und synthese von thieno(3,2-c)pyridinderivaten daraus
NO982549L (no) 5-naftalen-1-yl-1,3-dioksan-derivater, fremstilling og terapeutisk anvendelse derav
ECSP993031A (es) Derivados de propenil cefalosporina

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application